Willianne I M Vonk

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, The Netherlands
    J Biol Chem 285:28991-9000. 2010
  2. pmc The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expression
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, Netherlands Metabolomics Center, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    Cell Mol Life Sci 69:149-63. 2012
  3. pmc Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, and Netherlands Metabolomics Center, Utrecht, The Netherlands
    PLoS ONE 6:e29183. 2011
  4. pmc The Copper Metabolism MURR1 Domain Protein 1 (COMMD1) Modulates the Aggregation of Misfolded Protein Species in a Client-Specific Manner
    Willianne I M Vonk
    University Medical Center Utrecht, Department of Metabolic and Endocrine Diseases, and Netherlands Metabolomics Center, Utrecht, the Netherlands University Medical Center Utrecht, Complex Genetics Section, Utrecht, The Netherlands
    PLoS ONE 9:e92408. 2014
  5. doi Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity
    Patricia A J Muller
    Department of Metabolic and Endocrine Diseases, UMC Utrecht, Utrecht, The Netherlands
    Traffic 10:514-27. 2009
  6. doi Role of transition metals in the pathogenesis of amyotrophic lateral sclerosis
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, Netherlands Metabolomics Center, Utrecht, The Netherlands
    Biochem Soc Trans 36:1322-8. 2008

Collaborators

Detail Information

Publications6

  1. pmc Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, The Netherlands
    J Biol Chem 285:28991-9000. 2010
    ..Here, we identify COMMD1 as a novel protein regulating SOD1 activation and associate COMMD1 function with the production of free radicals...
  2. pmc The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expression
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, Netherlands Metabolomics Center, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands
    Cell Mol Life Sci 69:149-63. 2012
    ..Together, the presented data might provide a new direction for developing therapies to improve the residual exporting activity of unstable ATP7A mutant proteins, and suggests a potential role for COMMD1 in this process...
  3. pmc Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, and Netherlands Metabolomics Center, Utrecht, The Netherlands
    PLoS ONE 6:e29183. 2011
    ....
  4. pmc The Copper Metabolism MURR1 Domain Protein 1 (COMMD1) Modulates the Aggregation of Misfolded Protein Species in a Client-Specific Manner
    Willianne I M Vonk
    University Medical Center Utrecht, Department of Metabolic and Endocrine Diseases, and Netherlands Metabolomics Center, Utrecht, the Netherlands University Medical Center Utrecht, Complex Genetics Section, Utrecht, The Netherlands
    PLoS ONE 9:e92408. 2014
    ..Altogether, this study offers new research directions to expand our current knowledge on the mechanisms underlying aggregation disease pathologies. ..
  5. doi Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity
    Patricia A J Muller
    Department of Metabolic and Endocrine Diseases, UMC Utrecht, Utrecht, The Netherlands
    Traffic 10:514-27. 2009
    ..In conclusion, these data indicate that COMMD1 undergoes constitutive nucleocytoplasmic transport as a novel mechanism to regulate NF-kappaB and HIF-1 signaling...
  6. doi Role of transition metals in the pathogenesis of amyotrophic lateral sclerosis
    Willianne I M Vonk
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, Netherlands Metabolomics Center, Utrecht, The Netherlands
    Biochem Soc Trans 36:1322-8. 2008
    ..Recent data strengthen the hypothesis that these transition metals are excellent potential targets to develop an effective therapy for ALS...