Gerard H A Visser

..In this clinical opinion, the pros and cons will be discussed...

..However, in both trials FBS was still performed in the ST-analysis arm, and it is therefore still unknown if the observed results were indeed due to the ST-analysis or to the use of FBS in combination with ST-analysis...

..In this study, we investigated information sources used by general practitioners (GPs) and pharmacists and their common practices...

..To construct new Dutch reference curves for birthweight by parity, sex and ethnic background...

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..To compare long-term effects of neonatal treatment with dexamethasone or hydrocortisone for chronic lung disease of prematurity on the hypothalamus-pituitary-adrenal axis and the immune response in children at school age...

..Mortality did not differ in deliveries after 31 weeks of gestation, which is in contrast to recent data. Apparently, modern obstetrics is more effective in reducing mortality in DC twins...

..2%), and we related their outcome to perinatal factors, including macrosomia (birth weight >90th percentile)...

..To evaluate whether correct adherence to clinical guidelines might have led to prevention of cases with adverse neonatal outcome...

..To evaluate umbilical cord coiling in pregnancies with adverse outcome...

..Therefore monitoring during the morning could circumvent the suppressive effects of betamethasone...

..The oxytocin receptor antagonist atosiban and the calcium antagonist nifedipine appear to be effective in postponing delivery. However, information is lacking on their possible effects on the fetal biophysical profile...

..We confirmed associations between fetal death and both a maturation defect and hypercoiling and found an association between histological indication of fetal hypoxia/ischemia and a placental maturation defect...

..To evaluate the added value of the baseline T/QRS ratio to other known risk factors in predicting adverse outcome and interventions for suspected fetal distress...

..We reviewed our experience with this condition to determine the neurodevelopmental outcome of prenatally diagnosed cases with isolated HB complicated by hydrops fetalis...

..To determine mode of delivery and occurrence of uterine rupture in women with a previous caesarean section (CS) in the Netherlands...

..To estimate the relation between undercoiling and overcoiling of the umbilical cord and adverse pregnancy outcome...

..To determine maternal and perinatal morbidity and mortality after uterine rupture in the Netherlands...

..RDS and HELLP syndrome have been associated with oxidative stress and inflammatory processes...

..To study respiratory outcome in preterm small for gestational age (SGA) fetuses with or without signs of intrauterine growth restriction due to placental insufficiency, and with or without maternal hypertension...

..We describe the natural history and outcome of 24 infants with isolated CAVB diagnosed in utero, review the literature, and assess the risk factors that could predict outcome...

..A randomized controlled trial should be performed to confirm prior results and answer further questions regarding antenatal steroid treatment of these fetuses...

..No associations were found between prenatal maternal cortisol and the offspring's learning and memory...

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..However, the benefits of this policy as compared to single-course administration have not been proven...

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..Furthermore, the relation between SAF levels and adverse pregnancy outcomes was investigated...

..To compare the effects of ST-waveform analysis in combination with cardiotocography with conventional cardiotocography for intrapartum fetal monitoring...

..A first-choice SSRI type was not apparent. Bodily activity at high rate during non-REM sleep in SSRI-exposed fetuses is an abnormal phenomenon, but its significance for postnatal development is unclear...

..To evaluate the influence of intrapartum epidural analgesia on the occurrence of ST events of the fetal ECG...

..A disadvantage of application of the STAN method is that it is based on visual interpretation of the CTG, with large inter- and intraobserver variability. In spite of this shortcoming the method may be promising...

..We determined the presence of traditional and novel risk factors for cardiovascular disease in these women...

..To determine the frequency of ST-changes in the fetal electrocardiogram (ECG) both during normal and abnormal fetal heart (FHR) traces and to study relations with characteristics of pregnancy and delivery...

..This study was aimed at evaluating the accuracy of the CGMS in pregnant women with type 1 diabetes...

..Mechanisms underlying RSV bronchiolitis in healthy term infants are largely unknown. Sterile intraamniotic inflammation and chorioamnionitis have been associated with increased lung volume and compliance...

..To investigate if antenatal glucocorticoid treatment has an effect on hippocampal histology of the human preterm newborn...

..To determine if presence of the Roach muscle, a small muscle bundle lying just beside the umbilical artery, contributes to umbilical cord coiling...

..To determine the incidence, indication, association with caesarean section (CS) and outcome of emergency peripartum hysterectomy (EPH) in The Netherlands...

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..This is the first report of 4 cases with a transient fetal heart block in structurally normal hearts without maternal autoantibodies...

..Our objective was to compare the prognostic capacity of the L/S ratio and the LBC in the prediction of RDS from amniotic fluid that was obtained either transabdominally or vaginally...

..Their FRAP values were lower and the incidence of oxidative stress-related diseases was significantly higher in these infants...

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..Therefore we compared SAF at diagnosis in GDM patients with normal pregnancy. If SAF is elevated in GDM, future research could focus on the possible use of the AGE-Reader as a screening method for GDM...

..In case of suspected intra-uterine hypoxia, both animal and human studies suggest that maternal administration of allopurinol immediately prior to delivery reduces hypoxic-ischaemic encephalopathy...

..In the future ultrasonographic evaluation of the umbilical cord and the UCI may become an integral part of fetal assessment in high-risk pregnancies...

..39) and more attention regulation problems in toddlers (OR=1.46). CONCLUSIONS: Increased levels of maternal prenatal stress appear to be associated with temperamental and behavioral problems in toddlers...

..Tachysystole, with a pseudo-sinusoidal FHR pattern, may be a sign of a critical perinatal condition and recognition may be of vital importance...

..The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor...

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..To study whether antenatal or neonatal glucocorticoid therapy to reduce the incidence and severity of chronic lung disease in preterm infants is associated with long-term adverse cardiac effects and hypertension...

..To estimate the effectiveness of intrapartum fetal monitoring by cardiotocography plus ST analysis using a strict protocol for performance of fetal blood sampling...

..We compared the different techniques and investigated factors that influence visualization of the cervix. The data in this overview may be used to establish guidelines in clinical practice...

..4, 98.9, and 100%, respectively. BMI has no clinically significant influence on recording quality of FHR monitored with fECG. It can therefore be considered a good method for monitoring the fetal condition in pregnancies of obese women...

..After delivery, glycaemic control must be relaxed to prevent hypoglycaemia, especially in women who breastfeed...

..To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations...

..Fetal hypoxia is an important determinant of neonatal encephalopathy caused by birth asphyxia, in which hypoxia-induced free radical formation plays an important role...

..To investigate maternal, perinatal, and neonatal outcomes of pregnancies in women with type 1 diabetes in the Netherlands...

..It was the aim of this study to determine whether the CGMS accurately reflects glucose levels in pregnant women with type 1 diabetes mellitus...

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..Neuromotor development was poorer in DEX than the BMETH and REF groups. The HC group did not differ from REF and BMETH groups. We suggest that neonatal HC may be a "safer" alternative for DEX for the treatment of CLD...

..The purpose of this study was to visualize and quantify dynamic changes in the cervix and to study factors influencing cervical length...

..Validation of electrohysterography (EHG) as a method for uterine activity monitoring during labour by comparing with intra-uterine pressure catheter (IUPC) recordings...

..The aim of this study was to investigate the pharmacokinetics and pharmacodynamics of sotalol in the treatment of fetal tachycardia...

..CONCLUSIONS: Acidemia at birth increased the occurrence of severe IVH in preterm neonates and seizures in both preterm and full-term neonates. However, no significant effect of acidemia on long-term outcome could be demonstrated...

..g. accelerated fetal growth or hydramnios) (diagnosis-group)...

..This study explores decisional processes regarding termination of pregnancy because of Down syndrome and aims to identify possibilities for improving counseling...

..The possible effects are the product of placental transfer efficiency, time of administration and dose of the respective SSRI...

..Thrombotic thrombocytopenic purpura is a rare disease. However, in pregnant women it occurs more frequently. Thrombotic thrombocytopenic purpura may be a severe condition for both mother and fetus...

..Conclusion. HFUPR falls before and in relation to the time of onset of labor rather than in relation to gestational age...

..In control cases, this shortening does not occur. The intrapartum fetal QT interval may therefore provide additional information on the condition of the fetus...

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..Efforts must be made to avoid low BG, i.e. <3.9 mmol/l, when tightening glycemic control...

..To determine the opinion of Dutch gynaecologists and registrars on caesarean section (CS) on request...

..We examined the changes of maternal paroxetine concentrations during pregnancy in relation to cytochrome P450 (CYP) 2D6 genotype...

..This provides evidence that the achieved betamethasone levels are high enough to reach the compartment of either twin member...

..The pathophysiologic changes associated with cardiovascular disease may also be responsible for the increased incidence of pre-eclampsia in these women...

..5 to 1 mg/day IV, or flecainide 200 to 400 mg/day orally is proposed. Initiating direct fetal therapy may follow failure of transplacental therapy...

..We conclude that S-100 a and b and NSE are not suitable markers for neonatal brain damage. Brain-restricted proteins such as glial fibrillary acidic protein and B-50 seem more promising...