Eric Vermetten

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Hippocampal and amygdalar volumes in dissociative identity disorder
    Eric Vermetten
    Department of Psychiatry, Rudolf Magnus Institute of Neurosciences, University Medical Center, Int mailbox B01206, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Am J Psychiatry 163:630-6. 2006
  2. pmc Positron tomographic emission study of olfactory induced emotional recall in veterans with and without combat-related posttraumatic stress disorder
    Eric Vermetten
    University Medical Center, Utrecht, The Netherlands
    Psychopharmacol Bull 40:8-30. 2007
  3. pmc Alterations in stress reactivity after long-term treatment with paroxetine in women with posttraumatic stress disorder
    Eric Vermetten
    Rudolf Magnus Institute of Neurosciences, Department Psychiatry, University Medical Center, Int mailbox B01206, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:184-202. 2006
  4. ncbi request reprint Altered pain processing in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Arch Gen Psychiatry 64:76-85. 2007
  5. doi request reprint Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: a study assessing polysomnography with simultaneous blood sampling
    Saskia van Liempt
    Research Center Military Mental Health Care, Utrecht, The Netherlands
    Psychoneuroendocrinology 38:155-65. 2013
  6. doi request reprint Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1822-36. 2012
  7. doi request reprint A prospective study on personality and the cortisol awakening response to predict posttraumatic stress symptoms in response to military deployment
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    J Psychiatr Res 45:713-9. 2011
  8. doi request reprint Impact of impaired sleep on the development of PTSD symptoms in combat veterans: a prospective longitudinal cohort study
    Saskia van Liempt
    Research Center Military Mental Health Care, Utrecht, The Netherlands
    Depress Anxiety 30:469-74. 2013
  9. pmc IL-1β reactivity and the development of severe fatigue after military deployment: a longitudinal study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands
    J Neuroinflammation 9:205. 2012
  10. doi request reprint Glucocorticoid receptor number predicts increase in amygdala activity after severe stress
    Elbert Geuze
    Research Centre, Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1837-44. 2012

Collaborators

Detail Information

Publications56

  1. pmc Hippocampal and amygdalar volumes in dissociative identity disorder
    Eric Vermetten
    Department of Psychiatry, Rudolf Magnus Institute of Neurosciences, University Medical Center, Int mailbox B01206, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Am J Psychiatry 163:630-6. 2006
    ..The authors examined hippocampal and amygdalar volumes in patients with dissociative identity disorder, a disorder that has been associated with a history of severe childhood trauma...
  2. pmc Positron tomographic emission study of olfactory induced emotional recall in veterans with and without combat-related posttraumatic stress disorder
    Eric Vermetten
    University Medical Center, Utrecht, The Netherlands
    Psychopharmacol Bull 40:8-30. 2007
    ..Primitive brain systems involved in fear responsivity and survival also mediate smell, including the olfactory cortex and amygdala. The purpose of this study was to measure neural correlates of olfaction in PTSD...
  3. pmc Alterations in stress reactivity after long-term treatment with paroxetine in women with posttraumatic stress disorder
    Eric Vermetten
    Rudolf Magnus Institute of Neurosciences, Department Psychiatry, University Medical Center, Int mailbox B01206, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:184-202. 2006
    ..These results suggest that successful treatment with SSRI in chronic PTSD is associated with a trend for a decrease in baseline diurnal cortisol and with reduced cortisol reactivity to stress...
  4. ncbi request reprint Altered pain processing in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Arch Gen Psychiatry 64:76-85. 2007
    ..Several brain areas related to pain processing are implicated in PTSD. To our knowledge, no functional imaging study has discussed whether patients with PTSD experience and process pain in a different way than control subjects...
  5. doi request reprint Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: a study assessing polysomnography with simultaneous blood sampling
    Saskia van Liempt
    Research Center Military Mental Health Care, Utrecht, The Netherlands
    Psychoneuroendocrinology 38:155-65. 2013
    ..According to polysomnography (PSG), only minor changes in sleep architecture were described. This warrants alternative methods for assessing sleep regulation in PTSD...
  6. doi request reprint Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1822-36. 2012
    ..e. dexamethasone: DEX) assessed before military deployment predicts high levels of PTSD, depressive, and/or fatigue symptoms 6 months after return from deployment...
  7. doi request reprint A prospective study on personality and the cortisol awakening response to predict posttraumatic stress symptoms in response to military deployment
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    J Psychiatr Res 45:713-9. 2011
    ..However, the number of previous deployments was not related to development of PTSD symptoms. The total model explained 24% of variance in PTSD symptoms after military deployment...
  8. doi request reprint Impact of impaired sleep on the development of PTSD symptoms in combat veterans: a prospective longitudinal cohort study
    Saskia van Liempt
    Research Center Military Mental Health Care, Utrecht, The Netherlands
    Depress Anxiety 30:469-74. 2013
    ..This study investigates the impact of impaired sleep and nightmares before deployment on the development of PTSD symptoms...
  9. pmc IL-1β reactivity and the development of severe fatigue after military deployment: a longitudinal study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands
    J Neuroinflammation 9:205. 2012
    ..Based on this concept, we assessed the reactivity of peripheral blood cells to IL-1β in vitro as a novel approach to investigate whether severe fatigue is associated with increased pro-inflammatory signaling...
  10. doi request reprint Glucocorticoid receptor number predicts increase in amygdala activity after severe stress
    Elbert Geuze
    Research Centre, Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1837-44. 2012
    ..However, to the best of our knowledge, no previous study has investigated GR number in PBMCs and amygdala function in humans...
  11. pmc Cytokine production by leukocytes of military personnel with depressive symptoms after deployment to a combat-zone: a prospective, longitudinal study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center, Utrecht, Utrecht, The Netherlands
    PLoS ONE 6:e29142. 2011
    ..In addition, deployment to a combat-zone affects the capacity of T-cells and monocytes to produce cytokines and chemokines until at least 6 months after return...
  12. doi request reprint Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 71:309-16. 2012
    ..We investigated whether glucocorticoid receptor (GR) pathway components assessed in leukocytes before military deployment represent preexisting vulnerability factors for development of PTSD symptoms...
  13. ncbi request reprint Pharmacotherapeutic treatment of nightmares and insomnia in posttraumatic stress disorder: an overview of the literature
    Saskia van Liempt
    Rudolf Magnus Institute of Neurosciences and Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:502-7. 2006
    ..Objective parameters for insomnia and nightmares need to be identified for understanding underlying mechanisms of disturbed sleep in PTSD, and for evaluating therapy...
  14. doi request reprint Neuropsychological performance is related to current social and occupational functioning in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Depress Anxiety 26:7-15. 2009
    ..However, most of these studies had several methodological disadvantages. None of these studies assessed parameters related to social or occupational functioning...
  15. doi request reprint Differences in the response to the combined DEX-CRH test between PTSD patients with and without co-morbid depressive disorder
    Carien DE Kloet
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Psychoneuroendocrinology 33:313-20. 2008
    ....
  16. doi request reprint Thinner prefrontal cortex in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre, Military Mental Healthcare, Ministry of Defence, Utrecht, The Netherlands
    Neuroimage 41:675-81. 2008
    ..Cortical thickness correlated with memory measures in the veterans without PTSD, but not in the veterans with PTSD. Cortical thinning in these regions may thus correspond to functional abnormalities observed in patients with PTSD...
  17. doi request reprint Decreased nocturnal growth hormone secretion and sleep fragmentation in combat-related posttraumatic stress disorder; potential predictors of impaired memory consolidation
    Saskia van Liempt
    Research Centre Military Mental Healthcare, Utrecht, The Netherlands
    Psychoneuroendocrinology 36:1361-9. 2011
    ..We conducted a controlled study in which we assessed sleep fragmentation, nocturnal secretion of GH, and memory consolidation in patients with PTSD...
  18. doi request reprint Investigating the MMPI-2 trauma profile in treatment-seeking peacekeepers
    Arthur R Rademaker
    Department of Clinical and Health Psychology, Utrecht University, Utrecht, The Netherlands
    J Pers Assess 91:593-600. 2009
    ..The MMPI-2 proved to be useful in assessing the broad range of symptoms typically present in trauma populations as well as the severity of posttraumatic morbidity...
  19. ncbi request reprint Precuneal activity during encoding in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Ministry of Defense, Utrecht, The Netherlands
    Prog Brain Res 167:293-7. 2008
    ..The precuneus was less activated in veterans with PTSD, which correlated significantly with the severity of PTSD. Like fronto-temporal regions the precuneus is differentially activated during memory formation in veterans with PTSD...
  20. doi request reprint Deployment-related severe fatigue with depressive symptoms is associated with increased glucocorticoid binding to peripheral blood mononuclear cells
    Mirjam van Zuiden
    Laboratory of Psychoneuroimmunology, University Medical Center Utrecht, Utrecht, The Netherlands
    Brain Behav Immun 23:1132-9. 2009
    ..These results indicate that high glucocorticoid binding to PBMCs might represent a vulnerability factor for the development of severe fatigue with depressive symptoms after a sustained period of stress, such as deployment...
  21. ncbi request reprint Neuroimaging of pain perception in Dutch veterans with and without posttraumatic stress disorder: preliminary results
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan, 100 3584, CX, Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:401-4. 2006
    ..Fixed affects analysis demonstrated that stimuli subjectively perceived as more painful resulted in increased activation of the caudal ACC, whereas less painful stimuli resulted in increased activation of the rostral ACC in both groups...
  22. ncbi request reprint Functional brain imaging and the induction of traumatic recall: a cross-correlational review between neuroimaging and hypnosis
    Eric Vermetten
    University Medical Center, Central Military Hospital, Utrecht, The Netherlands
    Int J Clin Exp Hypn 52:280-312. 2004
    ....
  23. ncbi request reprint Neural correlates of associative learning and memory in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, PO Box 90 000, 3509AA Utrecht, The Netherlands
    J Psychiatr Res 42:659-69. 2008
    ..Deficits in memory performance in PTSD appear to be related to altered activity in fronto-temporal areas during both the encoding and retrieval phase of memory processing...
  24. doi request reprint Self-reported early trauma as a predictor of adult personality: a study in a military sample
    Arthur R Rademaker
    Utrecht University, and Research Institute for Psychology and Health and Research Centre Military Mental Healthcare, Utrecht, The Netherlands
    J Clin Psychol 64:863-75. 2008
    ..They show that early trauma may become ingrained in personality and hamper the potential to effectively engage in social interactions, increasing the risk of emotional and cognitive problems...
  25. ncbi request reprint Pharmacotherapy for disordered sleep in post-traumatic stress disorder: a systematic review
    Saskia van Liempt
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Int Clin Psychopharmacol 21:193-202. 2006
    ..Some recent studies show promising results, especially for alpha1-adrenoceptor and 5-HT2 receptor antagonists. However, randomized controlled trials with larger populations need to be conducted...
  26. ncbi request reprint Neuroanatomical changes associated with pharmacotherapy in posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, GA 30322, USA
    Ann N Y Acad Sci 1032:154-7. 2004
    ..Patients subjectively reported an improvement in cognition and work performance. These studies are consistent with the idea that antidepressants have a beneficial effect on hippocampal function in PTSD patients...
  27. ncbi request reprint Assessment of the hypothalamic-pituitary-adrenal axis over a 24-hour diurnal period and in response to neuroendocrine challenges in women with and without childhood sexual abuse and posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry, Emory University School of Medicine, Atlanta, Georgia, USA
    Biol Psychiatry 54:710-8. 2003
    ..We performed a comprehensive assessment of the HPA axis in women with and without a history of early childhood sexual abuse and posttraumatic stress disorder (PTSD)...
  28. pmc Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder
    Eric Vermetten
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA
    Biol Psychiatry 54:693-702. 2003
    ..This study assessed the effects of long-term treatment with paroxetine on hippocampal volume and declarative memory performance in PTSD...
  29. ncbi request reprint Neural correlates of memories of abandonment in women with and without borderline personality disorder
    Christian G Schmahl
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    Biol Psychiatry 54:142-51. 2003
    ..One particularly salient feature of the disorder is fear of abandonment. This pilot study was conducted to measure neural correlates of memories of abandonment in women with and without BPD...
  30. ncbi request reprint Higher cortisol levels following exposure to traumatic reminders in abuse-related PTSD
    Bernet M Elzinga
    Section of Clinical and Health Psychology, Leiden University, The Netherlands
    Neuropsychopharmacology 28:1656-65. 2003
    ..There was no association between memory performance and cortisol levels. These results are consistent with higher cortisol levels following exposure to traumatic stressors in PTSD...
  31. ncbi request reprint Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    Biol Psychiatry 53:879-89. 2003
    ..The purpose of this study was to assess neural correlates of emotionally valenced declarative memory in women with early childhood sexual abuse and PTSD...
  32. ncbi request reprint MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory Clinical Neuroscience Research Unit, Emory University School of Medicine, 1256 Briarcliff Road, Atlanta, GA 30306, USA
    Am J Psychiatry 160:924-32. 2003
    ..The purpose of this study was to measure both hippocampal structure and function in women with and without early childhood sexual abuse and the diagnosis of posttraumatic stress disorder (PTSD)...
  33. ncbi request reprint Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder
    Christian G Schmahl
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstrasse 5, D 79104 Freiburg, Germany
    Psychiatry Res 122:193-8. 2003
    ..9% smaller mean amygdala volume and a 13.1% smaller hippocampal volume, compared to controls. These findings are consistent with the hypothesis that alterations in the hippocampus and amygdala are associated with BPD...
  34. ncbi request reprint Olfaction as a traumatic reminder in posttraumatic stress disorder: case reports and review
    Eric Vermetten
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
    J Clin Psychiatry 64:202-7. 2003
    ..Though trauma-related smells have long been noted by clinicians to be precipitants of traumatic memories in patients with posttraumatic stress disorder (PTSD), very few reports have been published that document this...
  35. pmc Childhood trauma associated with smaller hippocampal volume in women with major depression
    Meena Vythilingam
    Mood and Anxiety Disorders Program, National Institute of Mental Health, 15K North Drive, Room 111, MSC 2670, Bethesda, MD 20892 2670, USA
    Am J Psychiatry 159:2072-80. 2002
    ..In this study, the volumes of the hippocampus and of control brain regions were measured in depressed women with and without childhood abuse and in healthy nonabused comparison subjects...
  36. ncbi request reprint Circuits and systems in stress. I. Preclinical studies
    Eric Vermetten
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Depress Anxiety 15:126-47. 2002
    ..Intensity and duration of the stressor, and timing of the stressor in life, have strong impact in this respect...
  37. ncbi request reprint Neural correlates of the classic color and emotional stroop in women with abuse-related posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, Georgia, USA
    Biol Psychiatry 55:612-20. 2004
    ..Dysfunction of the anterior cingulate/medial prefrontal cortex has been implicated in posttraumatic stress disorder (PTSD). The purpose of this study was to use the Stroop task as a probe of anterior cingulate function in PTSD...
  38. ncbi request reprint Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder
    Douglas Bremner
    Departments of Psychiatry and Behavioral Sciences and Radiology, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, Georgia, USA
    J Nerv Ment Dis 195:919-27. 2007
    ..These findings suggest that a resting hypocortisolemia in the afternoon hours with increased cortisol pulsatility is associated with childhood abuse-related PTSD in women...
  39. pmc Effects of antidepressant treatment on neural correlates of emotional and neutral declarative verbal memory in depression
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States
    J Affect Disord 101:99-111. 2007
    ..The purpose of this study was to examine the effects of treatment with antidepressants on verbal declarative memory in patients with depression...
  40. ncbi request reprint Psychophysiological reactivity to traumatic and abandonment scripts in borderline personality and posttraumatic stress disorders: a preliminary report
    Christian G Schmahl
    Department of Psychosomatic Medicine, Central Institute of Mental Health, J 5, D 68159 Mannheim, Germany
    Psychiatry Res 126:33-42. 2004
    ..A divergence in pathophysiology in these two disorders is suggested that may be linked to childhood trauma. However, this interpretation must be tested in a larger population...
  41. ncbi request reprint Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment
    Meena Vythilingam
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland 20892 2670, USA
    Biol Psychiatry 56:101-12. 2004
    ..However, the relationships between depression, hippocampal structure and function, and cortisol levels are unclear and the effects of antidepressant treatment on the measures are not well studied...
  42. ncbi request reprint Effects of glucocorticoids on declarative memory function in major depression
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 126 Briarcliff Road, Atlanta, GA 30306, USA
    Biol Psychiatry 55:811-5. 2004
    ..The purpose of this study was to assess the effects of the glucocorticoid, dexamethasone, on verbal declarative memory function in patients with untreated unipolar major depressive disorder (MDD)...
  43. ncbi request reprint A positron emission tomography study of memories of childhood abuse in borderline personality disorder
    Christian G Schmahl
    Department of Psychosomatic Medicine, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 55:759-65. 2004
    ..This pilot study was conducted to measure the neural correlates of recall of traumatic memories in women with and without BPD...
  44. ncbi request reprint Effects of dexamethasone on declarative memory function in posttraumatic stress disorder
    J Douglas Bremner
    Departments of Psychiatry and Behavioral Sciences and Radiology, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta 30306 GA, USA
    Psychiatry Res 129:1-10. 2004
    ....
  45. ncbi request reprint Deficits in verbal declarative memory function in women with childhood sexual abuse-related posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, Georgia, USA
    J Nerv Ment Dis 192:643-9. 2004
    ..These findings suggest that early abuse with PTSD is associated with deficits in verbal declarative memory, and that these effects are not related to the nonspecific effects of childhood abuse...
  46. pmc Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30306, USA
    Psychol Med 35:791-806. 2005
    ..No studies have examined neural correlates of fear conditioning and extinction in patients with post-traumatic stress disorder (PTSD)...
  47. ncbi request reprint Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, and Atlanta VA Medical Center, Decatur, GA, USA
    Am J Psychiatry 161:637-45. 2004
    ..The purpose of the present study was to assess hippocampal and prefrontal functioning during performance of a verbal declarative memory task in subjects with midlife major depression...
  48. ncbi request reprint Comorbidity of obsessive-compulsive disorder and depression: prevalence, symptom severity, and treatment effect
    Thea Overbeek
    Department of Psychiatry and Neuropsychology, Maastricht University, and the Academic Anxiety Center, Psychiatric Hospital Vijverdal, Maastricht, The Netherlands
    J Clin Psychiatry 63:1106-12. 2002
    ..The goal of this study was to investigate the co-occurrence of depressive disorders in obsessive-compulsive disorder (OCD) and the effect of these disorders on combined pharmacologic and behavioral treatment for OCD...
  49. ncbi request reprint Circuits and systems in stress. II. Applications to neurobiology and treatment in posttraumatic stress disorder
    Eric Vermetten
    Department of Psychiatry, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    Depress Anxiety 16:14-38. 2002
    ..Current and new targets for systems that play a role in the neural circuitry of PTSD are discussed. This material provides a basis for understanding the psychopathology of stress-related disorders, in particular PTSD...
  50. pmc Structural and functional plasticity of the human brain in posttraumatic stress disorder
    J Douglas Bremner
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
    Prog Brain Res 167:171-86. 2008
    ..Antidepressant treatments and changes in environment can reverse the effects of stress on hippocampal neurogenesis, and humans with PTSD showed increased hippocampal volume with both paroxetine and phenytoin...
  51. pmc Regional brain metabolic correlates of alpha-methylparatyrosine-induced depressive symptoms: implications for the neural circuitry of depression
    J Douglas Bremner
    Department of Psychiatry, Emory Center for Positron Emission Tomography, Emory University School of Medicine, Atlanta, GA, USA
    JAMA 289:3125-34. 2003
    ....
  52. ncbi request reprint PTSD and Vietnam Veterans
    Eric Vermetten
    Science 315:184-7; author reply 184-7. 2007
  53. ncbi request reprint Post-traumatic stress disorder: medicine or politics (not both)
    David Spiegel
    Lancet 369:992. 2007
  54. ncbi request reprint Epilogue: neuroendocrinology of PTSD
    Eric Vermetten
    Prog Brain Res 167:311-3. 2008
  55. ncbi request reprint Scientific study of the dissociative disorders
    Constance Dalenberg
    Psychother Psychosom 76:400-1; author reply 401-3. 2007
  56. ncbi request reprint Reduced volume of orbitofrontal cortex in major depression
    J Douglas Bremner
    Atlanta VA Medical Center, Decatur, Georgia, USA
    Biol Psychiatry 51:273-9. 2002
    ..The purpose of this study was to measure volume of orbitofrontal cortex and other frontal cortical subregions in patients with major depression...