LOUK VANDERSCHUREN

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Seeking-taking chain schedules of cocaine and sucrose self-administration: effects of reward size, reward omission, and α-flupenthixol
    M M J Veeneman
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 220:771-85. 2012
  2. pmc Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats
    Petra J J Baarendse
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 219:313-26. 2012
  3. pmc Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine
    M M J Veeneman
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 214:863-76. 2011
  4. pmc Methylphenidate disrupts social play behavior in adolescent rats
    Louk J M J Vanderschuren
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 33:2946-56. 2008
  5. doi request reprint Sensitization processes in drug addiction
    Louk J M J Vanderschuren
    Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Curr Top Behav Neurosci 3:179-95. 2010
  6. doi request reprint Anti-obesity drugs and neural circuits of feeding
    Roger A H Adan
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, UMC Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Trends Pharmacol Sci 29:208-17. 2008
  7. doi request reprint Cannabis and the developing brain: insights from behavior
    Viviana Trezza
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Pharmacol 585:441-52. 2008
  8. doi request reprint Inflexible and indifferent alcohol drinking in male mice
    Heidi M B Lesscher
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, The Netherlands
    Alcohol Clin Exp Res 34:1219-25. 2010
  9. doi request reprint A grandparent-influenced locus for alcohol preference on mouse chromosome 2
    Heidi M B Lesscher
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Pharmacogenet Genomics 19:719-29. 2009
  10. pmc Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms
    Viviana Trezza
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 34:2560-73. 2009

Research Grants

Collaborators

Detail Information

Publications16

  1. pmc Seeking-taking chain schedules of cocaine and sucrose self-administration: effects of reward size, reward omission, and α-flupenthixol
    M M J Veeneman
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 220:771-85. 2012
    ..However, the neurobehavioral characteristics of ST chain schedules are relatively unexplored...
  2. pmc Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats
    Petra J J Baarendse
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 219:313-26. 2012
    ..However, impulsive behavior is behaviorally and neurally heterogeneous, and several caveats remain in our understanding of the role of monoamines in impulse control...
  3. pmc Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine
    M M J Veeneman
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands
    Psychopharmacology (Berl) 214:863-76. 2011
    ..Stimulation of dopamine receptors plays an important role in drug reward, but not in the sensitizing properties of cocaine and morphine...
  4. pmc Methylphenidate disrupts social play behavior in adolescent rats
    Louk J M J Vanderschuren
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 33:2946-56. 2008
    ..However, given the importance of social play for development, these findings may also indicate an adverse side effect of methylphenidate...
  5. doi request reprint Sensitization processes in drug addiction
    Louk J M J Vanderschuren
    Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Curr Top Behav Neurosci 3:179-95. 2010
    ..However, detoxification and the gradual disappearance of tolerance and withdrawal symptoms may unmask sensitization, which could then play an important role in the high risk of relapse...
  6. doi request reprint Anti-obesity drugs and neural circuits of feeding
    Roger A H Adan
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, UMC Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Trends Pharmacol Sci 29:208-17. 2008
    ..Several potential drug targets are expressed in different neural circuits, implying that current and future obesity drugs act on partially overlapping systems that control food intake...
  7. doi request reprint Cannabis and the developing brain: insights from behavior
    Viviana Trezza
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Pharmacol 585:441-52. 2008
    ....
  8. doi request reprint Inflexible and indifferent alcohol drinking in male mice
    Heidi M B Lesscher
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, The Netherlands
    Alcohol Clin Exp Res 34:1219-25. 2010
    ....
  9. doi request reprint A grandparent-influenced locus for alcohol preference on mouse chromosome 2
    Heidi M B Lesscher
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Pharmacogenet Genomics 19:719-29. 2009
    ..In addition, mouse chromosome substitution strains were used to further evaluate the contribution of chromosome 2 to ethanol consumption...
  10. pmc Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms
    Viviana Trezza
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 34:2560-73. 2009
    ..Furthermore, the stimulating effects of nicotine and ethanol on social play behavior are independent of their anxiolytic-like properties...
  11. pmc Conditioned place preference induced by social play behavior: parametrics, extinction, reinstatement and disruption by methylphenidate
    Viviana Trezza
    Rudolf Magnus Institute of Neuroscience, Dept of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 19:659-69. 2009
    ..social play is likely to be the most rewarding aspect of social interaction in adolescent rats; 5. social context influences the subjective effects of methylphenidate...
  12. pmc Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats
    Viviana Trezza
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    J Pharmacol Exp Ther 328:343-50. 2009
    ..Furthermore, these results suggest that off-target effects may be responsible for some of the conflicting effects of anandamide transporter inhibitors on behavior...
  13. pmc Cannabinoid and opioid modulation of social play behavior in adolescent rats: differential behavioral mechanisms
    Viviana Trezza
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 18:519-30. 2008
    ....
  14. ncbi request reprint Bidirectional cannabinoid modulation of social behavior in adolescent rats
    Viviana Trezza
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Psychopharmacology (Berl) 197:217-27. 2008
    ..Marijuana use in adolescents is a highly social activity, and interacting endocannabinoid and opioid systems may modulate social reward. However, cannabinoid exposure has been reported to reduce social behavior...
  15. pmc Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats
    Judith R Homberg
    Hubrecht Institute, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
    Psychopharmacology (Berl) 195:175-82. 2007
    ....
  16. doi request reprint Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats
    Judith R Homberg
    Hubrecht Institute, Uppsalalaan 8, 3584, CT, Utrecht, The Netherlands
    Psychopharmacology (Berl) 200:367-80. 2008
    ..While individual differences in vulnerability to psychostimulants have been largely attributed to dopaminergic neurotransmission, the role of serotonin is not fully understood...

Research Grants3