Peter J M Van Haastert
Affiliation: University of Groningen
Country: The Netherlands
- Van Haastert P, Keizer Gunnink I, Kortholt A. Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement. Mol Biol Cell. 2017;28:922-934 pubmed publisher....
- Van Haastert P, Keizer Gunnink I, Kortholt A. The cytoskeleton regulates symmetry transitions in moving amoeboid cells. J Cell Sci. 2018;: pubmed publisher....
- Plak K, Veltman D, Fusetti F, Beeksma J, Rivero F, Van Haastert P, et al. GxcC connects Rap and Rac signaling during Dictyostelium development. BMC Cell Biol. 2013;14:6 pubmed publisher..GxcC provides a novel link between Rap and Rac signalling and is one of the Rap effectors regulating the progression of multicellular development. ..
- Van Haastert P, Veltman D. Chemotaxis: navigating by multiple signaling pathways. Sci STKE. 2007;2007:pe40 pubmed..In addition, selective pseudopod growth and retraction are more important in directing cell movement than is the place where new pseudopodia are formed. ..
- Van Haastert P. Chemotaxis: insights from the extending pseudopod. J Cell Sci. 2010;123:3031-7 pubmed publisher..In this Commentary, I review the findings of these recent experiments, which together provide a new view of cell movement and chemotaxis. ..
- Van Haastert P. Amoeboid cells use protrusions for walking, gliding and swimming. PLoS ONE. 2011;6:e27532 pubmed publisher..Calculations suggest that these bumps provide sufficient drag force to mediate the observed forward swimming of the cell. ..
- Plak K, Pots H, Van Haastert P, Kortholt A. Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells. BMC Cell Biol. 2016;17:1 pubmed publisher..In mammalian cells the established Rap1-talin interaction is indirect and acts through the scaffold protein - RIAM. Interestingly, direct binding of mouse Rap1 to the RA domain of Talin1 has recently been demonstrated. ..
- Postma M, Van Haastert P. Mathematics of Experimentally Generated Chemoattractant Gradients. Methods Mol Biol. 2016;1407:381-96 pubmed publisher....
- Van Haastert P, Keizer Gunnink I, Kortholt A. Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis. J Cell Biol. 2007;177:809-16 pubmed....