Peter J M Van Haastert

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. Van Haastert P, Keizer Gunnink I, Kortholt A. Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement. Mol Biol Cell. 2017;28:922-934 pubmed publisher
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  2. Van Haastert P, Keizer Gunnink I, Kortholt A. The cytoskeleton regulates symmetry transitions in moving amoeboid cells. J Cell Sci. 2018;: pubmed publisher
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  3. Plak K, Veltman D, Fusetti F, Beeksma J, Rivero F, Van Haastert P, et al. GxcC connects Rap and Rac signaling during Dictyostelium development. BMC Cell Biol. 2013;14:6 pubmed publisher
    ..GxcC provides a novel link between Rap and Rac signalling and is one of the Rap effectors regulating the progression of multicellular development. ..
  4. request reprint
    Van Haastert P, Veltman D. Chemotaxis: navigating by multiple signaling pathways. Sci STKE. 2007;2007:pe40 pubmed
    ..In addition, selective pseudopod growth and retraction are more important in directing cell movement than is the place where new pseudopodia are formed. ..
  5. Van Haastert P. Chemotaxis: insights from the extending pseudopod. J Cell Sci. 2010;123:3031-7 pubmed publisher
    ..In this Commentary, I review the findings of these recent experiments, which together provide a new view of cell movement and chemotaxis. ..
  6. Van Haastert P. Amoeboid cells use protrusions for walking, gliding and swimming. PLoS ONE. 2011;6:e27532 pubmed publisher
    ..Calculations suggest that these bumps provide sufficient drag force to mediate the observed forward swimming of the cell. ..
  7. Plak K, Pots H, Van Haastert P, Kortholt A. Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells. BMC Cell Biol. 2016;17:1 pubmed publisher
    ..In mammalian cells the established Rap1-talin interaction is indirect and acts through the scaffold protein - RIAM. Interestingly, direct binding of mouse Rap1 to the RA domain of Talin1 has recently been demonstrated. ..
  8. Postma M, Van Haastert P. Mathematics of Experimentally Generated Chemoattractant Gradients. Methods Mol Biol. 2016;1407:381-96 pubmed publisher
    ....
  9. Van Haastert P, Keizer Gunnink I, Kortholt A. Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis. J Cell Biol. 2007;177:809-16 pubmed
    ....

Detail Information

Publications9

  1. Van Haastert P, Keizer Gunnink I, Kortholt A. Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement. Mol Biol Cell. 2017;28:922-934 pubmed publisher
    ....
  2. Van Haastert P, Keizer Gunnink I, Kortholt A. The cytoskeleton regulates symmetry transitions in moving amoeboid cells. J Cell Sci. 2018;: pubmed publisher
    ....
  3. Plak K, Veltman D, Fusetti F, Beeksma J, Rivero F, Van Haastert P, et al. GxcC connects Rap and Rac signaling during Dictyostelium development. BMC Cell Biol. 2013;14:6 pubmed publisher
    ..GxcC provides a novel link between Rap and Rac signalling and is one of the Rap effectors regulating the progression of multicellular development. ..
  4. request reprint
    Van Haastert P, Veltman D. Chemotaxis: navigating by multiple signaling pathways. Sci STKE. 2007;2007:pe40 pubmed
    ..In addition, selective pseudopod growth and retraction are more important in directing cell movement than is the place where new pseudopodia are formed. ..
  5. Van Haastert P. Chemotaxis: insights from the extending pseudopod. J Cell Sci. 2010;123:3031-7 pubmed publisher
    ..In this Commentary, I review the findings of these recent experiments, which together provide a new view of cell movement and chemotaxis. ..
  6. Van Haastert P. Amoeboid cells use protrusions for walking, gliding and swimming. PLoS ONE. 2011;6:e27532 pubmed publisher
    ..Calculations suggest that these bumps provide sufficient drag force to mediate the observed forward swimming of the cell. ..
  7. Plak K, Pots H, Van Haastert P, Kortholt A. Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells. BMC Cell Biol. 2016;17:1 pubmed publisher
    ..In mammalian cells the established Rap1-talin interaction is indirect and acts through the scaffold protein - RIAM. Interestingly, direct binding of mouse Rap1 to the RA domain of Talin1 has recently been demonstrated. ..
  8. Postma M, Van Haastert P. Mathematics of Experimentally Generated Chemoattractant Gradients. Methods Mol Biol. 2016;1407:381-96 pubmed publisher
    ....
  9. Van Haastert P, Keizer Gunnink I, Kortholt A. Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis. J Cell Biol. 2007;177:809-16 pubmed
    ....