Jan van Gijn

Summary

Affiliation: University Medical Center
Country: The Netherlands

Publications

  1. ncbi The PROGRESS Trial: preventing strokes by lowering blood pressure in patients with cerebral ischemia. Emerging therapies: critique of an important advance
    Jan van Gijn
    Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Stroke 33:319-20. 2002
  2. ncbi René Descartes (1596-1650)
    J van Gijn
    Department of Neurology, room G03 228, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neurol 252:241-2. 2005
  3. pmc PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial [ISCRTN 74418480]
    Eric J van Breda
    Erasmus Medical Center Rotterdam, The Netherlands
    BMC Cardiovasc Disord 5:24. 2005
  4. ncbi Hermann Oppenheim (1858-1919)
    J van Gijn
    Department of Neurology, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neurol 251:1028-9. 2004
  5. ncbi From randomised trials to rational practice
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Cerebrovasc Dis 19:69-76. 2005
  6. ncbi The future of stroke neurology
    Jan van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    J Neurol 251:235-9. 2004
  7. ncbi Subarachnoid haemorrhage: diagnosis, causes and management
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Brain 124:249-78. 2001
  8. ncbi [The treatment of carpal tunnel syndrome]
    J van Gijn
    Universitair Medisch Centrum Utrecht, afd Neurologie, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 146:981-5. 2002
  9. ncbi [Diagnosis: not more than an agreement on disease entity]
    J van Gijn
    Ned Tijdschr Geneeskd 146:1672-4. 2002
  10. ncbi Aspirin and stroke prevention
    J van Gijn
    Department of Neurology, University Medical Centre, room G03 228, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Thromb Res 110:349-53. 2003

Detail Information

Publications99

  1. ncbi The PROGRESS Trial: preventing strokes by lowering blood pressure in patients with cerebral ischemia. Emerging therapies: critique of an important advance
    Jan van Gijn
    Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Stroke 33:319-20. 2002
  2. ncbi René Descartes (1596-1650)
    J van Gijn
    Department of Neurology, room G03 228, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neurol 252:241-2. 2005
  3. pmc PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial [ISCRTN 74418480]
    Eric J van Breda
    Erasmus Medical Center Rotterdam, The Netherlands
    BMC Cardiovasc Disord 5:24. 2005
    ..3 degrees C (95% CI: 0.1-0.5) in body temperature. We set out to test the hypothesis that early antipyretic therapy reduces the risk of death or dependency in patients with acute stroke, even if they are normothermic...
  4. ncbi Hermann Oppenheim (1858-1919)
    J van Gijn
    Department of Neurology, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neurol 251:1028-9. 2004
  5. ncbi From randomised trials to rational practice
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Cerebrovasc Dis 19:69-76. 2005
    ..Compassion, curiosity and doubt are the essential forces that keep the cycle moving. Conversely, the progress is slowed down by present-day legalism, which distorts investigator accountability and patient autonomy...
  6. ncbi The future of stroke neurology
    Jan van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    J Neurol 251:235-9. 2004
  7. ncbi Subarachnoid haemorrhage: diagnosis, causes and management
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Brain 124:249-78. 2001
    ..Once ischaemia has occurred, treatment regimens such as a combination of induced hypertension and hypervolaemia, or transluminal angioplasty, are plausible, but of unproven benefit...
  8. ncbi [The treatment of carpal tunnel syndrome]
    J van Gijn
    Universitair Medisch Centrum Utrecht, afd Neurologie, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 146:981-5. 2002
    ..The injection of corticosteroids near the carpal tunnel is reasonably safe and also effective, albeit mostly just in the short term; in most patients the symptoms recur within a few months...
  9. ncbi [Diagnosis: not more than an agreement on disease entity]
    J van Gijn
    Ned Tijdschr Geneeskd 146:1672-4. 2002
    ..The growth of biomedical knowledge often leads to diseases being redefined. Diseases are not independent entities but human constructions...
  10. ncbi Aspirin and stroke prevention
    J van Gijn
    Department of Neurology, University Medical Centre, room G03 228, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Thromb Res 110:349-53. 2003
    ..Platelet aggregation can probably still occur despite complete acetylation of platelets, via pathways other than COX-1 inhibition, but in vitro aggregation tests are an unreliable measure...
  11. ncbi The Vogts: Cécile (1875-1962) and Oskar (1870-1959)
    J van Gijn
    Dept of Neurology, room G03 228, University Medical Centre, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    J Neurol 250:1261-2. 2003
  12. ncbi Large subcortical infarcts: clinical features, risk factors, and long-term prognosis compared with cortical and small deep infarcts
    Patricia H A Halkes
    Department of Neurology, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht, Netherlands
    Stroke 37:1828-32. 2006
    ..In this study we compared risk factors, clinical features, and stroke recurrence in a large series of patients with large subcortical, cortical, or small deep infarcts...
  13. pmc An early rise in body temperature is related to unfavorable outcome after stroke: data from the PAIS study
    Heleen M den Hertog
    Department of Neurology, Erasmus MC University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    J Neurol 258:302-7. 2011
    ..30; 95% CI 1.05-1.63) and death (aOR 1.51; 95% CI 1.15-1.98). An early rise in body temperature rather than high body temperature on admission is a risk factor for unfavorable outcome in patients with acute stroke...
  14. doi Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin
    P H A Halkes
    Department of Neurology, Rudolf Magnus Institute of Neuroscience and Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 80:437-9. 2009
    ..63 (95% CI 0.58 to 0.68)) and in ESPS 2 with female sex and absence of ischaemic lesions on imaging (area under the ROC curve 0.64 (95% CI 0.59 to 0.69))...
  15. ncbi Risk of rebleeding after treatment of acute hydrocephalus in patients with aneurysmal subarachnoid hemorrhage
    Catharine A Hellingman
    Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Stroke 38:96-9. 2007
    ..We studied the risk of rebleeding in patients with subarachnoid hemorrhage during treatment for acute hydrocephalus...
  16. ncbi Subarachnoid haemorrhage
    Jan van Gijn
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, 3584CX Utrecht, Netherlands
    Lancet 369:306-18. 2007
    ..Hydrocephalus might cause gradual obtundation in the first few hours or days; it can be treated by lumbar puncture or ventricular drainage, dependent on the site of obstruction...
  17. ncbi Clinical practice. Acute ischemic stroke
    H Bart van der Worp
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    N Engl J Med 357:572-9. 2007
  18. ncbi Long-term occurrence of death and cardiovascular events in patients with transient ischaemic attack or minor ischaemic stroke: comparison between arterial and cardiac source of the index event
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 79:895-9. 2008
    ..Data on long term risks are scarce. We compared the long term risks of death and vascular events (VE) between these groups...
  19. ncbi Antiplatelet therapy in aneurysmal subarachnoid hemorrhage: a systematic review
    Sanne M Dorhout Mees
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    Stroke 34:2285-9. 2003
    ..Robust evidence, however, is lacking. We performed a systematic meta-analysis to determine whether antiplatelet therapy has a beneficial effect after SAH...
  20. ncbi Is the long-term prognosis of transient ischemic attack or minor ischemic stroke affected by the occurrence of nonfocal symptoms?
    Annette Compter
    From the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands A C, H B v d W, J V G, L J K, A A Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands P J K and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands A A
    Stroke 45:1318-23. 2014
    ..We assessed the relationship between nonfocal symptoms and the long-term risk of vascular events or death in patients with a transient ischemic attack or minor ischemic stroke...
  21. ncbi Study design and outcome measures in studies on aneurysmal subarachnoid hemorrhage
    Irene C van der Schaaf
    Department of Neurology, University Medical Center Utrecht, Utrecht, Netherlands
    Stroke 33:2043-6. 2002
    ..We assessed quality of study design and outcome measures and presence and precision of definitions concerning major complications of SAH in studies evaluating treatment strategies in patients with aneurysmal SAH...
  22. ncbi Classification of cause of death after stroke in clinical research
    Patricia H A Halkes
    Department of Neurology, Rudolf Magnus Institute, University Medical Center Utrecht, The Netherlands
    Stroke 37:1521-4. 2006
    ..We aimed to develop guidelines for classifying such events...
  23. ncbi Repeated screening for intracranial aneurysms in familial subarachnoid hemorrhage
    Marieke J H Wermer
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Stroke 34:2788-91. 2003
    ..The benefit of repeated screening and the interval at which screening should be performed are unknown. We studied patient compliance and the yield of repeated screening for familial intracranial aneurysms...
  24. pmc Acute headache as a presenting symptom of tacrolimus encephalopathy
    I M Kiemeneij
    Department of Neurology, University Medical Centre Utrecht, St Elisabeth Medical Centre Tilburg, Netherlands
    J Neurol Neurosurg Psychiatry 74:1126-7. 2003
    ..Both her clinical condition improved and the lesions disappeared completely after withdrawal of tacrolimus, suggesting that her condition could be explained by a tacrolimus encephalopathy...
  25. pmc Correction: PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN74418480]
    Heleen M den Hertog
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    BMC Cardiovasc Disord 8:29. 2008
    ..Therefore, the planned primary analysis of the PAIS study has been changed from fixed dichotomization of the mRS to a sliding dichotomy analysis...
  26. ncbi Excimer laser-assisted high-flow extracranial/intracranial bypass in patients with symptomatic carotid artery occlusion at high risk of recurrent cerebral ischemia: safety and long-term outcome
    Catharina J M Klijn
    University Department of Neurology, University Medical Center Utrecht, and the Rudolf Magnus Institute of Neurosciences, Utrecht, The Netherlands
    Stroke 33:2451-8. 2002
    ....
  27. ncbi Venous stasis retinopathy in symptomatic carotid artery occlusion: prevalence, cause, and outcome
    Catharina J M Klijn
    University Department of Neurology, University Medical Center Utrecht and the Rudolf Magnus Institute for Neurosciences, Utrecht, The Netherlands
    Stroke 33:695-701. 2002
    ..The aim of this study was to gain insight into the prevalence, cause, and outcome of VSR in patients with symptomatic CAO...
  28. ncbi Effectiveness of neurosurgical clip application in patients with aneurysmal subarachnoid hemorrhage
    Eva H Brilstra
    University Department of Neurology and Neurosurgery, University of Utrecht, The Netherlands
    J Neurosurg 97:1036-41. 2002
    ..The authors assessed the magnitude of the reduction in poor outcomes that accompanies a strategy aimed at surgery...
  29. pmc Anticipation and phenotype in familial intracranial aneurysms
    Y M Ruigrok
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, PO Box 85500, 3500 GA Utrecht, Netherlands
    J Neurol Neurosurg Psychiatry 75:1436-42. 2004
    ..In familial intracranial aneurysms there is evidence for genetic heterogeneity, probably from mutations at separate loci...
  30. pmc Functional status and use of healthcare facilities in long-term survivors of transient ischaemic attack or minor ischaemic stroke
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 77:1238-43. 2006
    ..Stroke may have a major effect on survivors and on the healthcare system...
  31. ncbi Severity of cerebral white matter lesions and infarcts in patients with transient or moderately disabling cerebral ischaemia: reproducibility of grading by neurologists
    E L L M De Schryver
    Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Eur J Neurol 13:901-3. 2006
    ..Such assessment may prevent unnecessary risk with oral anticoagulation in secondary prevention after cerebral ischaemia of arterial origin, of which the efficacy is currently being assessed in ESPRIT...
  32. ncbi [The history of epilepsy in the Dutch Journal of Medicine]
    D J Nieuwkamp
    Universitair Medisch Centrum, afd Neurologie, Utrecht
    Ned Tijdschr Geneeskd 147:2522-6. 2003
    ..Types of treatment varied according to the current opinion on its causes. In most patients the best results are obtained through drug treatment; for a few, surgery is necessary...
  33. pmc Type of stroke after transient monocular blindness or retinal infarction of presumed arterial origin
    E L L M De Schryver
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, H 02 128, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 77:734-8. 2006
    ..Little information is available on the type of subsequent ischaemic strokes that may occur (anterior or posterior circulation and small vessel or large vessel)...
  34. pmc Early circulating levels of endothelial cell activation markers in aneurysmal subarachnoid haemorrhage: associations with cerebral ischaemic events and outcome
    C J M Frijns
    Department of Neurology, University Medical Centre Utrecht, Utrecht, Netherlands
    J Neurol Neurosurg Psychiatry 77:77-83. 2006
    ..To investigate the relation of endothelial cell activation with delayed cerebral ischaemia (DCI) and outcome after subarachnoid haemorrhage (SAH)...
  35. pmc Visual inspection versus spectrophotometry in detecting bilirubin in cerebrospinal fluid
    F H H Linn
    Department of Neurology, University Medical Centre Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    J Neurol Neurosurg Psychiatry 76:1452-4. 2005
    ..To compare the diagnostic accuracy of visual inspection and spectrophotometry for identifying the presence of bilirubin in the cerebrospinal fluid (CSF)...
  36. ncbi Non-adherence to aspirin or oral anticoagulants in secondary prevention after ischaemic stroke
    E L L M De Schryver
    Dept of Neurology, University Medical Centre, Utrecht, The Netherlands
    J Neurol 252:1316-21. 2005
    ..We investigated determinants of non-adherence in patients who used aspirin or oral anticoagulation after cerebral ischaemia of arterial origin...
  37. ncbi Magnesium sulfate in aneurysmal subarachnoid hemorrhage: a randomized controlled trial
    Walter M van den Bergh
    Department of Neurology, Room G03 124 University Medical Center Utrecht, PO Box 85500 3508 GA Utrecht, The Netherlands
    Stroke 36:1011-5. 2005
    ..We aimed to assess whether magnesium reduces the frequency of delayed cerebral ischemia (DCI) in patients with aneurysmal SAH...
  38. ncbi Acute confusional state as presenting feature in aneurysmal subarachnoid hemorrhage: frequency and characteristics
    J C Reijneveld
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    J Neurol 247:112-6. 2000
    ..In our series, one per 70 patients with SAH presents with ACS. Keys to early diagnosis of SAH in patients presenting with ACS are a preceding period of loss of consciousness and severe headache on neurological assessment...
  39. ncbi [Treatment of optic neuritis]
    H B van der Worp
    Universitair Medisch Centrum Utrecht, afd Neurologie, HP G 03 228, Heidelberglaan 100, 3584 CX Utrecht
    Ned Tijdschr Geneeskd 148:61-5. 2004
    ..Treatment with interferon beta-Ia in high-risk patients also slows down the progression to clinically definite MS, but the long-term benefits are uncertain. MR imaging of the brain has implications for prognosis but not for treatment...
  40. ncbi Characteristics of intracranial aneurysms in patients with familial subarachnoid hemorrhage
    Y M Ruigrok
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, 3500 GA Utrecht, The Netherlands
    Neurology 62:891-4. 2004
    ..The authors compared the size of ruptured aneurysms and the number of aneurysms between patients with familial subarachnoid hemorrhage (SAH) and those with sporadic SAH...
  41. ncbi [Surgical decompression in space-occupying cerebral infarct; notification of a randomized trial]
    J Hofmeijer
    Universitair Medisch Centrum Utrecht, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 147:2594-6. 2003
    ....
  42. ncbi Oral anticoagulants versus antiplatelet therapy for preventing further vascular events after transient ischemic attack or minor stroke of presumed arterial origin
    A Algra
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Stroke 34:234-5. 2003
  43. ncbi [Cerebral white matter lesions in the elderly: vascular risk factors and cognitive consequences]
    F E de Leeuw
    Universitair Medisch Centrum Utrecht, afd Neurologie, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 145:2067-71. 2001
    ..Prospective studies are needed to confirm causality and to study the efficacy of treatment of vascular risk factors...
  44. ncbi Outcome in patients with symptomatic occlusion of the internal carotid artery or intracranial arterial lesions: a meta-analysis of the role of baseline characteristics and type of antithrombotic treatment
    C J Klijn
    University Department of Neurology, University Medical Centre Utrecht and the Rudolf Magnus Institute for Neurosciences, Utrecht, The Netherlands
    Cerebrovasc Dis 12:228-34. 2001
    ..In addition, we investigated the effect of treatment with aspirin or oral anticoagulation on recurrent stroke rate and assessed whether the incidence of recurrent stroke has decreased over the years...
  45. ncbi Lack of evidence for a poor haemodynamic or metabolic state of the brain in patients with haemodynamic clinical features associated with carotid artery occlusion
    C J Klijn
    University Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands
    Cerebrovasc Dis 12:99-107. 2001
    ..To assess whether patients with carotid artery occlusion (CAO) who have clinical features suggesting a haemodynamic origin have a poor haemodynamic or metabolic state of the brain...
  46. ncbi Reproducibility of measurements of cerebral infarct volume on CT scans
    H B van der Worp
    Department of Neurology, University Medical Center, Utrecht, Netherlands
    Stroke 32:424-30. 2001
    ..Infarct volume is increasingly used as an outcome measure in clinical trials of therapies for acute ischemic stroke. We tested which of 5 different methods to measure infarct size or volume on CT scans has the highest reproducibility...
  47. ncbi Recurrent ischemia in symptomatic carotid occlusion: prognostic value of hemodynamic factors
    C J Klijn
    University Department of Neurology, Clinical Neurophysiology and Neurosurgery, the Julius Center for Patient Oriented Research, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurology 55:1806-12. 2000
    ..To identify hemodynamic factors that predict recurrence of ipsilateral cerebral ischemic events in patients with symptomatic carotid artery occlusion (CAO)...
  48. ncbi A new type of extracranial/intracranial bypass for recurrent haemodynamic transient ischaemic attacks
    C J Klijn
    University Department of Neurology, University Hospital Utrecht, The Netherlands
    Cerebrovasc Dis 8:184-7. 1998
    ....
  49. ncbi Diagnostic value of myotactic reflexes in axonal and demyelinating polyneuropathy
    G W van Dijk
    Department of Clinical Neurophysiology, University Hospital Utrecht, The Netherlands
    Neurology 53:1573-6. 1999
    ..Myotatic reflexes may therefore be useful for the distinction between axonal and demyelinating polyneuropathy...
  50. ncbi Initial loss of consciousness and risk of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
    J W Hop
    University Department of Neurology, Utrecht, The Netherlands
    Stroke 30:2268-71. 1999
    ..We studied the prognostic value for DCI of 2 factors: the duration of unconsciousness after the hemorrhage and the presence of risk factors for atherosclerosis...
  51. ncbi Rebleeding, secondary ischemia, and timing of operation in patients with subarachnoid hemorrhage
    E H Brilstra
    University Department of Neurology, Utrecht, The Netherlands
    Neurology 55:1656-60. 2000
    ....
  52. ncbi Magnetic resonance techniques for the identification of patients with symptomatic carotid artery occlusion at high risk of cerebral ischemic events
    C J Klijn
    Department of Neurology, University Medical Center Utrecht and the Rudolf Magnus Institute for Neurosciences, Utrecht, Netherlands
    Stroke 31:3001-7. 2000
    ..We sought to assess whether MRI, MR angiography, or (1)H MR spectroscopy can be used to identify patients with symptomatic carotid artery occlusion (CAO) who are at high risk of recurrent ipsilateral cerebral ischemic events...
  53. ncbi Follow-up of idiopathic thunderclap headache in general practice
    F H Linn
    University Department of Neurology, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Neurol 246:946-8. 1999
    ..Thus, although no episodes of SAH occurred after ITH during long-term follow-up, one-half of patients with ITH had a lower level of daily functioning, and one-eighth had reduced working capacity, specifically because of headache...
  54. ncbi How do general practitioners diagnose and manage patients with transient monocular loss of vision of sudden onset?
    R C Donders
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    J Neurol 246:1145-50. 1999
    ..They refer only three-quarters of patients with probable ITMB to a specialist and start antithrombotic medication in only one-third of these patients. Therefore further education with regard to transient monocular blindness is needed...
  55. ncbi Perimesencephalic hemorrhage and CT angiography: A decision analysis
    Y M Ruigrok
    Department of Neurology, University Medical Center Utrecht, Netherlands
    Stroke 31:2976-83. 2000
    ..We used decision analysis to compare possible diagnostic strategies in these patients...
  56. ncbi Quality of life in patients with axonal polyneuropathy
    L L Teunissen
    University Medical Centre Utrecht, Department of Neurology, The Netherlands
    J Neurol 247:195-9. 2000
    ....
  57. ncbi Quality of life in patients and partners after aneurysmal subarachnoid hemorrhage
    J W Hop
    University Department of Neurology, Utrecht, The Netherlands
    Stroke 29:798-804. 1998
    ..We assessed functional outcome and quality of life (QoL) in patients with SAH and their partners...
  58. ncbi The effect of tirilazad mesylate on infarct volume of patients with acute ischemic stroke
    H B van der Worp
    Department of Neurology, University Medical Center, Utrecht, The Netherlands
    Neurology 58:133-5. 2002
    ..These effects were reduced to nonsignificant trends after adjustment for imbalances in baseline characteristics. In conclusion, early treatment of patients with tirilazad has no effect on infarct volume...
  59. ncbi Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review
    J W Hop
    University Department of Neurology, Utrecht, Netherlands
    Stroke 28:660-4. 1997
    ..To assess whether the case-fatality rate has improved after the introduction of new management strategies, we studied outcome in all population-based studies from 1960 onward...
  60. ncbi Endothelial cell activation is associated with cerebral white matter lesions in patients with cerebrovascular disease
    F E de Leeuw
    Departments of Neurology, University Medical Center Utrecht, C03 236, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Ann N Y Acad Sci 977:306-14. 2002
    ..Possibly, this activation represents the influence of vascular factors on the cerebral endothelium as a prelude to increasingly severe small vessel disease...
  61. ncbi CT patterns and long-term outcome in patients with an aneurysmal type of subarachnoid hemorrhage and repeatedly negative angiograms
    Ynte M Ruigrok
    Department of Neurology, University Medical Center, Utrecht, The Netherlands
    Cerebrovasc Dis 14:221-7. 2002
    ..Subdivisions according to the center of hemorrhage once the anterior cisterns are involved is not helpful in identifying patients with good or poor outcome...
  62. ncbi Collateral circulation via the ophthalmic artery or leptomeningeal vessels is associated with impaired cerebral vasoreactivity in patients with symptomatic carotid artery occlusion
    J Hofmeijer
    University Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands
    Cerebrovasc Dis 14:22-6. 2002
    ....
  63. ncbi Soluble adhesion molecules reflect endothelial cell activation in ischemic stroke and in carotid atherosclerosis
    C J Frijns
    Department of Neurology, University Hospital Utrecht, Netherlands
    Stroke 28:2214-8. 1997
    ....
  64. ncbi Quality of life, anxiety, and depression in patients with an untreated intracranial aneurysm or arteriovenous malformation
    Irene C van der Schaaf
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Stroke 33:440-3. 2002
    ..The objective of this study was to assess the health-related quality of life and symptoms of anxiety and depression in patients who are aware of the presence of a patent aneurysm or arteriovenous malformation...
  65. pmc The notion of "warning leaks" in subarachnoid haemorrhage: are such patients in fact admitted with a rebleed?
    F H Linn
    University Department of Neurology, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 68:332-6. 2000
    ..An alternative explanation is recall bias. The clinical and radiological features of patients with SAH were studied in relation to previous headaches or later rebleeding...
  66. ncbi Symptomatic carotid artery occlusion. A reappraisal of hemodynamic factors
    C J Klijn
    University Department of Neurology, University Hospital Utrecht, Netherlands
    Stroke 28:2084-93. 1997
    ..This evidence is found in both clinical features and ancillary investigations, particularly measurements of cerebral blood flow...
  67. ncbi [Totally paralyzed or brain dead?]
    G W van Dijk
    Universitair Medisch Centrum Utrecht, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 145:2513-6. 2001
    ..If the cause is insufficiently, the presence of brain death should be seriously doubted, unless an isoelectric EEG is observed...
  68. ncbi Prevalence and risk of rupture of intracranial aneurysms: a systematic review
    G J Rinkel
    University Department of Neurology Utrecht, The Netherlands
    Stroke 29:251-6. 1998
    ..We conducted a systematic review on prevalence and risk of rupture of intracranial aneurysms and classified the data according to study design, study population, and aneurysm characteristics...
  69. ncbi Psychogenic pseudoptosis
    J W Hop
    University Department of Neurology, Utrecht, The Netherlands
    J Neurol 244:623-4. 1997
    ..All showed depression of the eyebrow on the affected side. The clinical course varied: in two patients the symptom resolved spontaneously after positive reassurance; in the third patient it remained unchanged for 2 years...
  70. doi Facts versus theories: an everlasting struggle. The Johann Jakob Wepfer Award 2010
    Jan van Gijn
    Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Cerebrovasc Dis 30:330-9. 2010
    ..Physicians still speculate more often than they care to admit...
  71. doi Intracranial aneurysms treated with coil placement: test characteristics of follow-up MR angiography--multicenter study
    Joanna D Schaafsma
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Radiology 256:209-18. 2010
    ..To determine the test characteristics of magnetic resonance (MR) angiography in the assessment of occlusion of aneurysms treated with coil placement...
  72. doi Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group
    Mervyn D I Vergouwen
    Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
    Stroke 41:2391-5. 2010
    ..The second issue is the variability and overlap of terms used to describe each phenomenon. This makes comparisons among studies difficult...
  73. pmc Mental status and health-related quality of life in an elderly population 15 years after limited cerebral ischaemia
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol 254:1018-25. 2007
    ..Our study was designed to describe the mental status and health-related quality of life (HRQoL) in long-term survivors of TIA or minor ischaemic stroke (MIS) and evaluate associations of mental and physical factors with HR-QoL...
  74. ncbi Magnesium in aneurysmal subarachnoid hemorrhage (MASH II) phase III clinical trial MASH-II study group
    Sanne M Dorhout Mees
    University Medical Center Utrecht, room G03 228, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Int J Stroke 3:63-5. 2008
    ..In a phase II randomized clinical trial of 283 patients, magnesium treatment reduced the risk of DCI by 34% and of poor outcome by 23%...
  75. ncbi Anticoagulation in ischemic stroke: opportunities in arterial disease
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Cerebrovasc Dis 20:101-8. 2005
    ....
  76. ncbi [Chronic low back pain: the failure of organic medicine]
    J van Gijn
    Universitair Medisch Centrum Utrecht, afd Neurologie, Heidelberglaan 100, 3584 CX Utrecht
    Ned Tijdschr Geneeskd 151:1553-6. 2007
    ..Patients will continue to seek magic cures from 'quacks with a knife' as long as medical specialists are insufficiently trained to deal with unexplained somatic symptoms...
  77. ncbi Herman Boerhaave (1668-1738)
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    J Neurol 249:231-2. 2002
  78. ncbi Long-term survival and vascular event risk after transient ischaemic attack or minor ischaemic stroke: a cohort study
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, Netherlands
    Lancet 365:2098-104. 2005
    ..We aimed to restudy these risks in a prospective cohort of patients after TIA or minor ischaemic stroke (Rankin grade< or =3), after 10 years or more...
  79. ncbi Timing of aneurysm surgery in subarachnoid haemorrhage--an observational study in The Netherlands
    D J Nieuwkamp
    Department of Neurology, University Medical Centre, Utrecht, Utrecht, The Netherlands
    Acta Neurochir (Wien) 147:815-21. 2005
    ..We performed a retrospective observational study on the timing of aneurysm surgery in The Netherlands over a two-year period...
  80. ncbi Endothelial cell activation after subarachnoid hemorrhage
    Catharina J M Frijns
    Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurosurgery 50:1223-9; discussion 1229-30. 2002
    ..We analyzed the relationships of concentrations to initial clinical conditions, treatment modalities, and the occurrence of delayed cerebral ischemia...
  81. ncbi Prevalence and predictors of unexplained neurological symptoms in an academic neurology outpatient clinic--an observational study
    Tom J Snijders
    University Medical Centre Utrecht, Department of Neurology, Rom C03 236, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Neurol 251:66-71. 2004
    ....
  82. ncbi Classification of outcomes events in the Dutch TIA trial: prognostic value of accepted and rejected events
    Dejana R Jovanović
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Curr Med Res Opin 20:255-8. 2004
    ....
  83. ncbi Spinal dural arteriovenous fistulas: a congestive myelopathy that initially mimics a peripheral nerve disorder
    K Jellema
    Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands
    Brain 129:3150-64. 2006
    ..In any middle aged male patient with ascending motor or sensory deficits in the legs, SDAVF should be considered in order to prevent irreversible handicap...
  84. doi Accuracy and inter-observer variation in the classification of dysarthria from speech recordings
    S Fonville
    Department of Neurology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    J Neurol 255:1545-8. 2008
    ..We therefore studied the accuracy and the inter- observer agreement in the classification of dysarthrias on the basis of perceptual analysis alone...
  85. pmc Spinal dural arteriovenous fistulas: clinical features in 80 patients
    K Jellema
    Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands
    J Neurol Neurosurg Psychiatry 74:1438-40. 2003
    ....
  86. ncbi [Collaboration in the first-line setting in medically unexplained symptoms: from powerlessness to coordination]
    Nikki C Makkes
    Stichting Overvecht Gezond, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A5393. 2013
    ..Together with the nurse practitioner, he initiated a multidisciplinary collaboration and coordinated all the other professionals involved. The patient, now more trusting, visits her GP regularly. Her symptoms still exist...
  87. ncbi The spectrum of presentations of venous infarction caused by deep cerebral vein thrombosis
    Walter M van den Bergh
    Department of Neurology, University Medical Center Utrecht, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 65:192-6. 2005
    ..The diagnosis should be strongly suspected if the patient is a young woman, if the lesion is within the basal ganglia or thalamus, and especially if it is bilateral...
  88. ncbi [An expert should be a teacher rather than a process supervisor]
    Jan van Gijn
    Universitair Medisch Centrum Utrecht, afd Neurologie, Utrecht
    Ned Tijdschr Geneeskd 153:949. 2009
    ..Oddly enough some regard this as an advantage. In general it is a shoddy substitute because teaching is an art, because students cherish proper explanations and because the students are deprived of...
  89. ncbi Blood supply of the posterior cerebral artery by the carotid system on angiograms
    Jaqueline C F Jongen
    Department of Neurology, Atrium Medical Centre, PO Box 4446, 6401 CX Heerlen, The Netherlands
    J Neurol 249:455-60. 2002
    ..However, anatomical studies indicate that in some people the supply of the posterior cerebral artery is via the carotid system. We investigated how often such a developmental variant in the cerebral blood supply was present during life...
  90. ncbi Antifibrinolytic therapy for aneurysmal subarachnoid hemorrhage: a major update of a cochrane review
    Yvo Roos
    The Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
    Stroke 34:2308-9. 2003
  91. ncbi Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies
    Valery L Feigin
    Clinical Trials Research Unit, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand
    Stroke 36:2773-80. 2005
    ..After a 1996 review from our group on risk factors for subarachnoid hemorrhage (SAH), much new information has become available. This article provides an updated overview of risk factors for SAH...
  92. ncbi Interaction between hypertension, apoE, and cerebral white matter lesions
    Frank Erik de Leeuw
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Stroke 35:1057-60. 2004
    ..The epsilon4 allele of the apolipoprotein E gene (apoE) may be a candidate because this allele is associated with both the vascular risk factors and the consequences (cognitive impairment, dementia) of WMLs...
  93. ncbi Direction of flow in posterior communicating artery on magnetic resonance angiography in patients with occipital lobe infarcts
    Jacqueline C F Jongen
    Department of Neurology, Hospital Zevenaar, PO Box 9000, 6900 GA Zevenaar, Netherlands
    Stroke 35:104-8. 2004
    ..We studied the presence and direction of flow in the posterior communicating artery (PCoA) in patients with an occipital lobe infarct and in healthy controls...
  94. ncbi ['the Journal keeps physicians well informed' Interview by Hans van Maanen]
    Jan van Gijn
    Ned Tijdschr Geneeskd 151:18-20. 2007
  95. ncbi Lumbar spinal stenosis
    Jan van Gijn
    N Engl J Med 358:2647; author reply 2647-8. 2008
  96. ncbi Reduction of body temperature with paracetamol in patients with acute stroke: randomised clinical trials are needed
    Eric J van Breda
    Cerebrovasc Dis 18:350; author reply 351. 2004
  97. ncbi The pathology of sensory aphasia, with an analysis of fifty cases in which Broca's centre was not diseased. By M. Allen Starr, MD. Brain 1889: 12; 82-99; with A remarkable case of aphasia. Acute and complete destruction by embolic softening of the left mo
    Jan van Gijn
    Brain 130:1175-7. 2007
  98. ncbi Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke
    Peter M Rothwell
    Stroke Prevention Research Unit, University of Oxford, UK
    Stroke 35:2300-5. 2004
    ..Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention...
  99. doi Interpretation of ESPRIT in the FASTER trial
    Ale Algra
    Lancet Neurol 7:198-9; author reply 199. 2008