Research Topics
Genomes and Genes | Dirk J van VeldhuisenSummaryAffiliation: University Hospital Groningen Country: The Netherlands Publications
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Publications
High- versus low-dose ACE inhibition in chronic heart failure: a double-blind, placebo-controlled study of imidaprilD J van Veldhuisen
Department of Cardiology Thoraxcenter, University Hospital Groningen, The Netherlands
J Am Coll Cardiol 32:1811-8. 1998..5 mg, 5 mg and 10 mg) of the long-acting ACE inhibitor imidapril...
The electrocardiogram in traumatic right atrial ruptureD J van Veldhuisen
Department of Cardiology Thoraxcentre, University Hospital Groningen, The Netherlands
Int J Cardiol 71:179-80. 1999..On admission an electrocardiogram (ECG) was recorded which is highly remarkable and, retrospectively, suggestive for the diagnosis. The patient died soon after the ECG, and the diagnosis was made at autopsy...
The underreporting of results and possible mechanisms of 'negative' drug trials in patients with chronic heart failureD J van Veldhuisen
Department of Cardiology Thoraxcentre, University Hospital Groningen, P O Box 30001, 9700 RB, Groningen, The Netherlands
Int J Cardiol 80:19-27. 2001..In this article we will discuss some of these trials that were conducted in the last 10 years, since we believe they may provide insight into the pathophysiology and treatment options in CHF...
Renal dysfunction is associated with shorter telomere length in heart failureLiza S M Wong
Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
Clin Res Cardiol 98:629-34. 2009..We explored the association between leukocyte telomere length, a marker for biological age, and renal function in patients with CHF...
Differential associations between renal function and "modifiable" risk factors in patients with chronic heart failureTom D J Smilde
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Clin Res Cardiol 98:121-9. 2009..Our aim was to determine different pathophysiologic markers that are associated with reduced renal function in CHF...
Effects of rosuvastatin on coronary flow reserve and metabolic mismatch in patients with heart failure (from the CORONA Study)Pim van der Harst
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 105:517-21. 2010....
Myocardial perfusion reserve after a PET-driven revascularization procedure: a strong prognostic factorRiemer H J A Slart
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
J Nucl Med 52:873-9. 2011..In the present study, we investigated whether MPR is related to survival in ischemic heart disease (IHD) patients after a PET-driven intervention...
Inflammation and anaemia in a broad spectrum of patients with heart failureLennaert Kleijn
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Heart 98:1237-41. 2012..Although inflammation is assumed to be an important cause of anaemia, the association between anaemia and inflammatory markers in patients with HF has not been well established...
Renal function dependent association of AGTR1 polymorphism (A1166C) and electrocardiographic left-ventricular hypertrophyTom D J Smilde
Thorax Center, Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am J Hypertens 20:1097-103. 2007..We studied whether renal function modulates the association between RAS polymorphisms and LVH in a cross-sectional study of 8592 inhabitants of Groningen...
Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemiaB Daan Westenbrink
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
Cardiovasc Drugs Ther 22:265-74. 2008..We aimed to evaluate whether ischemia is required for erythropoietin (EPO) induced stimulation of endothelial progenitor cells (EPCs) and their related effects on endothelial and cardiac function...
Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27Rudolf A de Boer
Thoraxcenter, Department of Cardiology, University Hospital Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands
J Mol Med (Berl) 82:678-87. 2004..This process is prevented by both AT1 receptor blockade and TYR, and therefore inhibition of either pathway is equally efficacious in restoring LV function and architecture...
Persistent atrial fibrillation is associated with appropriate shocks and heart failure in patients with left ventricular dysfunction treated with an implantable cardioverter defibrillatorMichiel Rienstra
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am Heart J 153:120-6. 2007....
Anaemia is associated with shorter leucocyte telomere length in patients with chronic heart failureLiza S M Wong
Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
Eur J Heart Fail 12:348-53. 2010..We hypothesize that short telomere length contributes to the susceptibility to develop anaemia in patients with CHF...
Prediction of functional recovery after revascularization in patients with coronary artery disease and left ventricular dysfunction by gated FDG-PETRiemer H J A Slart
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
J Nucl Cardiol 13:210-9. 2006....
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunctionJasper W L Hartog
Department of Cardiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
Eur J Heart Fail 12:397-403. 2010..To investigate the relationship between advanced glycation end-products (AGEs) and diastolic function and the response to blood pressure treatment in patients with hypertension and diastolic dysfunction...
The effect of rate control on quality of life in patients with permanent atrial fibrillation: data from the RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation II) studyHessel F Groenveld
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Am Coll Cardiol 58:1795-803. 2011..The aim of this study was to investigate the influence of rate control on quality of life (QOL)...
Caregiver burden in partners of Heart Failure patients; limited influence of disease severityMarie Louise Luttik
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Eur J Heart Fail 9:695-701. 2007..However providing care may cause burden and affect the health of these partners. The aim of this study was to investigate determinants of caregiver burden in order to identify caregivers who are at risk...
Verapamil versus digoxin and acute versus routine serial cardioversion for the improvement of rhythm control for persistent atrial fibrillationMartin E W Hemels
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Am Coll Cardiol 48:1001-9. 2006..CONCLUSIONS: An acute serial cardioversion strategy does not improve long-term rhythm control in comparison with a routine serial cardioversion strategy. Furthermore, verapamil has no beneficial effect in a serial cardioversion strategy...
Pregnancy after biventricular repair for pulmonary atresia with ventricular septal defectWillem Drenthen
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am J Cardiol 98:262-6. 2006..Infertility and menstrual cycle disorders do not appear to be more prevalent, except for a high incidence of primary amenorrhea...
Urinary neutrophil gelatinase associated lipocalin (NGAL), a marker of tubular damage, is increased in patients with chronic heart failureKevin Damman
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Eur J Heart Fail 10:997-1000. 2008..In conclusion, renal impairment in CHF patients is not only characterised by decreased eGFR and increased UAE, but also by the presence of tubular damage, as measured by increased urinary NGAL concentrations...
Ischemic patterns assessed by positron emission tomography predict adverse outcome in patients with idiopathic dilated cardiomyopathyRichard M de Jong
Thoraxcenter, Department of Cardiology, University Medical Centre Groningen, Hanzeplein 1, P O Box 30 001, 9700 RB, Groningen, The Netherlands
J Nucl Cardiol 16:769-74. 2009..Our aim was to assess the prognostic relevance of PET-mismatch between stress myocardial perfusion and glucose uptake on clinical outcome in DCM...
Effect of rate and rhythm control on left ventricular function and cardiac dimensions in patients with persistent atrial fibrillation: results from the RAte Control versus Electrical Cardioversion for Persistent Atrial Fibrillation (RACE) studyVincent E Hagens
Department of Cardiology, University Hospital, Groningen, The Netherlands
Heart Rhythm 2:19-24. 2005..CONCLUSIONS: Routine rate control prevents deterioration of left ventricular function. Maintenance of sinus rhythm is associated with improvement of left ventricular function and reduction of atrial sizes...
Importance of heart rate during exercise for response to cardiac resynchronization therapyAlexander H Maass
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Cardiovasc Electrophysiol 20:773-80. 2009..Cardiac resynchronization therapy (CRT) is an established therapy for patients with severe heart failure and mechanical dyssynchrony. Response is only achieved in 60-70% of patients...
Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rateKevin Damman
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Heart 96:1297-302. 2010..The prognostic impact of reduced glomerular filtration rate (GFR) in chronic heart failure (CHF) is increasingly recognised, but little is known about tubular damage in these patients...
Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuriaPim van der Harst
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 102:223-5. 2008..Male gender was associated with a significantly larger reduction in CRP compared to female gender. In conclusion, contrary to previous observational studies, no effect of angiotensin-converting enzyme inhibition on CRP levels was found...
Rate control versus rhythm control for patients with persistent atrial fibrillation with mild to moderate heart failure: results from the RAte Control versus Electrical cardioversion (RACE) studyVincent E Hagens
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am Heart J 149:1106-11. 2005..However, if sinus rhythm can be maintained, outcome may be improved. A prospective randomized trial is necessary to confirm these results...
Comparison between the prognostic value of left ventricular function and myocardial perfusion reserve in patients with ischemic heart diseaseRene A Tio
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
J Nucl Med 50:214-9. 2009..In addition, MPR determines survival in patients with hypertrophic and dilated cardiomyopathies. In the present study, we evaluated whether MPR also determines survival in patients with IHD...
Levels of hematopoiesis inhibitor N-acetyl-seryl-aspartyl-lysyl-proline partially explain the occurrence of anemia in heart failurePeter van der Meer
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Circulation 112:1743-7. 2005..The aim of the present study was to determine possible mechanisms linking anemia to renin-angiotensin system activity in CHF patients...
Mild renal dysfunction is associated with electrocardiographic left ventricular hypertrophyTom D J Smilde
Department of Cardiology, Thoraxcenter, University Hospital Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Gronigen, The Netherlands
Am J Hypertens 18:342-7. 2005..We studied the relation between renal dysfunction and LVH in a cross-sectional study in 8592 inhabitants from Groningen, The Netherlands...
Right ventricular pacing and the risk of heart failure in implantable cardioverter-defibrillator patientsMarcelle D Smit
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Heart Rhythm 3:1397-403. 2006..50; 95% CI 1.02-2.20; P = .04). CONCLUSION: RV pacing was associated with an increased risk of HF in asymptomatic ICD patients, particularly in those with preexistent left ventricular dysfunction...
Effect of lenient versus strict rate control on cardiac remodeling in patients with atrial fibrillation data of the RACE II (RAte Control Efficacy in permanent atrial fibrillation II) studyMarcelle D Smit
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Am Coll Cardiol 58:942-9. 2011..The aim of this study was to evaluate echocardiographic remodeling in permanent atrial fibrillation (AF) patients treated with either lenient or strict rate control...
Pretreatment with ACE inhibitors improves acute outcome of electrical cardioversion in patients with persistent atrial fibrillationTrudeke Van Noord
Department of Cardiology, Thoraxcenter, University Hospital Groningen, P O Box 30, 001, 9700RB Groningen, The Netherlands
BMC Cardiovasc Disord 5:3. 2005..The renin-angiotensin system may play a important role in this. The aim of this study was to investigate the role of angiotensin-converting enzyme (ACE) inhibitor use on efficacy of ECV, and occurrence of subacute recurrences...
Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarctionPeter van der Meer
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
J Am Coll Cardiol 46:125-33. 2005..We assessed the effects of erythropoietin (EPO) treatment in a rat model of post-myocardial infarction (MI) heart failure...
Pregnancy in women with corrected tetralogy of Fallot: occurrence and predictors of adverse eventsAli Balci
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am Heart J 161:307-13. 2011..Our aim is to investigate the magnitude and determinants of pregnancy outcome in women with corrected ToF...
A single dose of erythropoietin in ST-elevation myocardial infarctionAdriaan A Voors
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Eur Heart J 31:2593-600. 2010..Clinical Trial Registration Information: NCT00449488; http://www.clinicaltrials.gov/ct2/show/NCT00449488?term=voors&rank=2...
Lenient versus strict rate control in patients with atrial fibrillationIsabelle C Van Gelder
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
N Engl J Med 362:1363-73. 2010..We hypothesized that lenient rate control is not inferior to strict rate control for preventing cardiovascular morbidity and mortality in patients with permanent atrial fibrillation...
Usefulness of preoperative C-reactive protein and soluble intercellular adhesion molecule-1 level for predicting future cardiovascular events after coronary artery bypass graftingPim van der Harst
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 97:1697-701. 2006....
Prediction of functional recovery after revascularization in patients with chronic ischaemic left ventricular dysfunction: head-to-head comparison between 99mTc-sestamibi/18F-FDG DISA SPECT and 13N-ammonia/ 18F-FDG PETRiemer H J A Slart
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, P O Box 30001, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
Eur J Nucl Med Mol Imaging 33:716-23. 2006..The aim of this study was to compare the diagnostic performance of PET and DISA SPECT for the prediction of improvement in regional and global LV function as well as LV reverse remodelling after revascularization...
Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) studyVincent E Hagens
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 98:929-32. 2006..In conclusion, the treatment of underlying disease, rather than the heart rhythm, seems essential to prevent mortality...
Worsening renal function and prognosis in heart failure: systematic review and meta-analysisKevin Damman
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Card Fail 13:599-608. 2007..The present study was designed to establish the proportion of patients with HF that exhibits (WRF) and the associated risk for mortality and hospitalization by conducting a systematic review and meta-analysis...
Endogenous erythropoietin and outcome in heart failureAnne M S Belonje
Departments of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Circulation 121:245-51. 2010..This study aims to analyze the clinical and prognostic value of erythropoietin levels in relation to hemoglobin in a large cohort of HF patients...
Effect of intensive versus moderate lipid lowering on endothelial function and vascular responsiveness to angiotensin II in stable coronary artery diseasePim van der Harst
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 96:1361-4. 2005..05). Endothelium improvement was accompanied by decreased vascular response to angiotensin II (p = 0.039). These findings suggest a mechanism for the clinical benefit of intensive lipid-lowering treatment in coronary heart disease...
Imaging techniques in nuclear cardiology for the assessment of myocardial viabilityRiemer H J A Slart
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
Int J Cardiovasc Imaging 22:63-80. 2006..Evaluation of the clinical role of these creative new possibilities warrants investigation...
Effects of C-reactive protein and cholesterol on responsiveness in vitro of the internal thoracic artery to angiotensin II in patients having coronary artery bypass graftingPim van der Harst
Department of Cardiology, Thoraxcenter, University of Groningen, Groningen, The Netherlands
Am J Cardiol 98:751-3. 2006..In conclusion, our results suggest that CRP and cholesterol act synergistically on vascular responsiveness to angiotensin II...
Quality of life and depressive symptoms in the elderly: a comparison between patients with heart failure and age- and gender-matched community controlsIvonne Lesman-Leegte
Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
J Card Fail 15:17-23. 2009..We compared QoL and depressive symptoms of a HF population with an age- and gender-matched sample of community dwelling elderly...
Erythropoietin in cardiac disease: new features of an old drugWillem Peter T Ruifrok
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Eur J Pharmacol 585:270-7. 2008....
C-reactive protein and microalbuminuria are associated with atrial fibrillationFolkert W Asselbergs
Department of Clinical Pharmacology, University of Groningen, Groningen, The Netherlands
Int J Cardiol 98:73-7. 2005..We hypothesized that microalbuminuria and C-reactive protein (CRP), a marker of generalized vascular damage and inflammation, respectively, are associated with AF...
Outcome of pregnancy in women with congenital heart disease: a literature reviewWillem Drenthen
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
J Am Coll Cardiol 49:2303-11. 2007..The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD...
Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patientsJasper W L Hartog
Department of Cardiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
J Card Fail 14:596-602. 2008..The aim of our study was to assess whether AGE accumulation in dialysis patients is related to the presence of diastolic dysfunction...
Difference in long-term prognostic value of renal function between ischemic and non-ischemic mild heart failureTom D J Smilde
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
Int J Cardiol 107:73-7. 2006..e. renal) vascular atherosclerosis. The aim of the present study is to evaluate the prognostic value of renal function in both ischemic and non-ischemic mild chronic heart failure...
Possible association between telomere length and renal dysfunction in patients with chronic heart failurePim van der Harst
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Cardiol 102:207-10. 2008..Further studies will be needed to determine whether shorter leukocyte telomere length is the cause or consequence in this population and whether it plays a role in the prognosis of renal dysfunction in HF...
Acute administration of angiotensin converting enzyme inhibitors in thrombolysed myocardial infarction patients is associated with a decreased incidence of heart failure, but an increased re-infarction riskAdriaan A Voors
Department of Cardiology, University Hospital Groningen, The Netherlands
Cardiovasc Drugs Ther 19:119-24. 2005..The aim of the present study was to evaluate the effects of acute ACE-inhibitor treatment...
Congestion in chronic systolic heart failure is related to renal dysfunction and increased mortalityKevin Damman
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Eur J Heart Fail 12:974-82. 2010..To investigate the relationship between signs and symptoms of congestion, renal impairment and outcome in chronic heart failure (CHF) patients...
Fertility, pregnancy and delivery in women after biventricular repair for double outlet right ventricleWillem Drenthen
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Cardiology 109:105-9. 2008..To investigate outcome of pregnancy and fertility in women with double outlet right ventricle (DORV)...
Use of cystatin C levels in estimating renal function and prognosis in patients with chronic systolic heart failureKevin Damman
Department of Cardiology, University Medical Center Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
Heart 98:319-24. 2012..Estimates of glomerular filtration rate (GFR), including creatinine and creatinine based formulae, are inaccurate in extremes of GFR and substantially biased in patients with chronic heart failure (CHF)...
Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarctionYoulan L Gu
Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB, Groningen, The Netherlands
Clin Res Cardiol 100:1069-76. 2011....
Low prevalence of B-type natriuretic peptide levels < 100 pg/mL in patients with heart failure at hospital dischargeJochem Hogenhuis
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am Heart J 151:1012.e1-5. 2006..Therefore, we aimed to investigate the prevalence and characteristics of stabilized patients with BNP levels < 100 pg/mL before discharge after admission for decompensated heart failure HF...
Influence of age on natriuretic peptides in patients with chronic heart failure: a comparison between ANP/NT-ANP and BNP/NT-proBNPJochem Hogenhuis
Thoraxcenter, Department of Cardiology, University Hospital Groningen, P.O. Box 30.001, Groningen 9700 RB, The Netherlands
Eur J Heart Fail 7:81-6. 2005..However, in these CHF patients the influence of age on the levels of all natriuretic peptides was modest, and comparable to several other factors...
Sertraline causes strong coronary vasodilation: possible relevance for cardioprotection by selective serotonin reuptake inhibitorsJoost P van Melle
Thorax Center, Departments of Cardiology, University Hospital Groningen, POB 30 001 Groningen, The Netherlands
Cardiovasc Drugs Ther 18:441-7. 2004..Vaso active effects of the SSRI sertraline were studied in rings of rat aorta, human Internal Mammary Arteries (IMAs) and in Langendorff perfused rat hearts...
Prognostic importance of renal function in patients with early heart failure and mild left ventricular dysfunctionTom D J Smilde
Department of Cardiology, Thoraxcenter, University Hospital Groningen, Groningen, The Netherlands
Am J Cardiol 94:240-3. 2004..16/10 ml/min/1.73 m(2), p = 0.003) was the only additional independent predictor of cardiovascular mortality in patients with early heart failure...
Gender-related differences in rhythm control treatment in persistent atrial fibrillation: data of the Rate Control Versus Electrical Cardioversion (RACE) studyMichiel Rienstra
Department of Cardiology, University Medical Center, University of Groningen, Groningen, The Netherlands
J Am Coll Cardiol 46:1298-306. 2005..Because treatment strategy did not influence QoL in female patients, a rate control approach may be considered in these patients...
Clinical characteristics of persistent lone atrial fibrillation in the RACE studyMichiel Rienstra
Department of Cardiology, Northern Center of Healthcare Research, University Hospital, Groningen, The Netherlands
Am J Cardiol 94:1486-90. 2004..Despite the absence of demonstrable cardiovascular and cerebrovascular disease, lone AF is associated with bleeding and thromboembolism...
Clustering of RR intervals predicts effective electrical cardioversion for atrial fibrillationMaarten P van den Berg
Department of Cardiology, Thoraxcenter, University Hospital Groningen, Groningen, The Netherlands
J Cardiovasc Electrophysiol 15:1027-33. 2004..It was hypothesized that electrical cardioversion (ECV) would be more effective in AF patients with clustering, because clustering might reflect a higher degree of organization of atrial fibrillatory activity...
Hemoglobin levels and 30-day mortality in patients after myocardial infarctionErik Lipsic
Department of Cardiology/Thorax Center, University Hospital Groningen, The Netherlands
Int J Cardiol 100:289-92. 2005..76, CI 1.08-2.85; p=0.02). CONCLUSIONS: Lower levels of hemoglobin are associated with higher short-term mortality in patients with acute MI. Specific therapeutic strategies in anemic patients with MI should be further considered...
Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injuryPeter van der Meer
Department of Cardiology, University Hospital Groningen, Groningen, The Netherlands
Eur J Heart Fail 6:853-9. 2004..02) and coronary flow (P=0.01). CONCLUSION: The present data suggest that a functional EPO-R is present in rat adult cardiac tissue and that exogenous EPO administration improves cardiac function after ischemia/reperfusion injury...
