Morris A Swertz

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. ncbi Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases
    Morris A Swertz
    Groningen Bioinformatics Center, Faculty of Medical Sciences and Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, The Netherlands
    Bioinformatics 20:2075-83. 2004
  2. ncbi xQTL workbench: a scalable web environment for multi-level QTL analysis
    Danny Arends
    Groningen Bioinformatics Centre, University of Groningen, Groningen, The Netherlands
    Bioinformatics 28:1042-4. 2012
  3. ncbi Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans
    Yang Li
    Groningen Bioinformatics Centre, University of Groningen, 9751 NN, Haren, The Netherlands
    Genetics 186:405-10. 2010
  4. ncbi MetaNetwork: a computational protocol for the genetic study of metabolic networks
    Jingyuan Fu
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Protoc 2:685-94. 2007
  5. ncbi The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button
    Morris A Swertz
    Genomics Coordination Center, Groningen Bioinformatics Center, University of Groningen and Department of Genetics, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands
    BMC Bioinformatics 11:S12. 2010
  6. ncbi XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
    Morris A Swertz
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Genome Biol 11:R27. 2010
  7. ncbi designGG: an R-package and web tool for the optimal design of genetical genomics experiments
    Yang Li
    Groningen Bioinformatics Center, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    BMC Bioinformatics 10:188. 2009
  8. ncbi PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis
    Richard A Scheltema
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands
    Anal Chem 83:2786-93. 2011
  9. ncbi A high-throughput processing service for retention time alignment of complex proteomics and metabolomics LC-MS data
    Isthiaq Ahmad
    Analytical Biochemistry, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Bioinformatics 27:1176-8. 2011
  10. ncbi The international dystrophic epidermolysis bullosa patient registry: an online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations
    Peter C van den Akker
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hum Mutat 32:1100-7. 2011

Collaborators

Detail Information

Publications13

  1. ncbi Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases
    Morris A Swertz
    Groningen Bioinformatics Center, Faculty of Medical Sciences and Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, The Netherlands
    Bioinformatics 20:2075-83. 2004
    ..Here, we report on the decision process for the case of a molecular genetics group establishing a microarray laboratory...
  2. ncbi xQTL workbench: a scalable web environment for multi-level QTL analysis
    Danny Arends
    Groningen Bioinformatics Centre, University of Groningen, Groningen, The Netherlands
    Bioinformatics 28:1042-4. 2012
    ..All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator...
  3. ncbi Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans
    Yang Li
    Groningen Bioinformatics Centre, University of Groningen, 9751 NN, Haren, The Netherlands
    Genetics 186:405-10. 2010
    ..Our findings suggest that the regulatory mechanism of alternative splicing in C. elegans is robust toward genetic variation at the genome-wide scale, which is in striking contrast to earlier observations in humans...
  4. ncbi MetaNetwork: a computational protocol for the genetic study of metabolic networks
    Jingyuan Fu
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Protoc 2:685-94. 2007
    ..This way MetaNetwork will contribute to a better integration of such data into systems biology...
  5. ncbi The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button
    Morris A Swertz
    Genomics Coordination Center, Groningen Bioinformatics Center, University of Groningen and Department of Genetics, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands
    BMC Bioinformatics 11:S12. 2010
    ..We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed...
  6. ncbi XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
    Morris A Swertz
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Genome Biol 11:R27. 2010
    ..Current functionality includes tools ranging from eQTL analysis in mouse to genome-wide association studies in humans...
  7. ncbi designGG: an R-package and web tool for the optimal design of genetical genomics experiments
    Yang Li
    Groningen Bioinformatics Center, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    BMC Bioinformatics 10:188. 2009
    ..The optimal design of such genetical genomics experiments in a cost-efficient and effective way is not trivial...
  8. ncbi PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis
    Richard A Scheltema
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands
    Anal Chem 83:2786-93. 2011
    ..The PeakML/mzMatch software is freely available at http://mzmatch.sourceforge.net, with documentation, tutorials, and a community forum...
  9. ncbi A high-throughput processing service for retention time alignment of complex proteomics and metabolomics LC-MS data
    Isthiaq Ahmad
    Analytical Biochemistry, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Bioinformatics 27:1176-8. 2011
    ..myexperiment.org/workflows/1283.html. Command line tool is available at http://www.nbpp.nl/Warp2D_commandline.zip. CONTACT: p.l.horvatovich@rug.nl SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online...
  10. ncbi The international dystrophic epidermolysis bullosa patient registry: an online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations
    Peter C van den Akker
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hum Mutat 32:1100-7. 2011
    ..Altogether, this registry will greatly benefit the DEB patients...
  11. ncbi Beyond standardization: dynamic software infrastructures for systems biology
    Morris A Swertz
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Rev Genet 8:235-43. 2007
    ..We argue that a minimal computer language, and a software tool called a generator, can be used to quickly produce customized software infrastructures that 'systems biologists really want to have'...
  12. ncbi Combining microarrays and genetic analysis
    Rudi Alberts
    Groningen Bioinformatics Centre, University of Groningen, Kerklaan 30, 9751 NN, Haren, The Netherlands
    Brief Bioinform 6:135-45. 2005
    ..It is shown how to fully exploit the power of genetics through optimal experimental design and analysis for two major microarray technologies, cDNA two-colour arrays and Affymetrix short oligonucleotide arrays...
  13. ncbi Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms
    Tjakko J van Ham
    Department of Genetics, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    EMBO Mol Med 1:360-70. 2009
    ....