Morris A Swertz

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. ncbi request reprint Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases
    Morris A Swertz
    Groningen Bioinformatics Center, Faculty of Medical Sciences and Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, The Netherlands
    Bioinformatics 20:2075-83. 2004
  2. pmc WormQTLHD--a web database for linking human disease to natural variation data in C. elegans
    K Joeri van der Velde
    Genomics Coordination Center, University of Groningen, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands, Groningen Bioinformatics Center, University of Groningen, P O Box 11103, 9700 CC Groningen, The Netherlands, Department of Genetics, University of Groningen, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands, Department of Bioinformatics, Hanze University of Applied Sciences, Groningen, Zernikeplein 11, 9747 AS, The Netherlands and Laboratory of Nematology, Wageningen University, 6708 PB Wageningen, The Netherlands
    Nucleic Acids Res 42:D794-801. 2014
  3. pmc xQTL workbench: a scalable web environment for multi-level QTL analysis
    Danny Arends
    Groningen Bioinformatics Centre, University of Groningen, Groningen, The Netherlands
    Bioinformatics 28:1042-4. 2012
  4. pmc designGG: an R-package and web tool for the optimal design of genetical genomics experiments
    Yang Li
    Groningen Bioinformatics Center, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    BMC Bioinformatics 10:188. 2009
  5. pmc Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans
    Yang Li
    Groningen Bioinformatics Centre, University of Groningen, 9751 NN, Haren, The Netherlands
    Genetics 186:405-10. 2010
  6. ncbi request reprint MetaNetwork: a computational protocol for the genetic study of metabolic networks
    Jingyuan Fu
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Protoc 2:685-94. 2007
  7. pmc The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button
    Morris A Swertz
    Genomics Coordination Center, Groningen Bioinformatics Center, University of Groningen and Department of Genetics, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands
    BMC Bioinformatics 11:S12. 2010
  8. pmc XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
    Morris A Swertz
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Genome Biol 11:R27. 2010
  9. doi request reprint PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis
    Richard A Scheltema
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands
    Anal Chem 83:2786-93. 2011
  10. ncbi request reprint An overview and online registry of microvillus inclusion disease patients and their MYO5B mutations
    K Joeri van der Velde
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen, University of Groningen, The Netherlands
    Hum Mutat 34:1597-605. 2013

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases
    Morris A Swertz
    Groningen Bioinformatics Center, Faculty of Medical Sciences and Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, The Netherlands
    Bioinformatics 20:2075-83. 2004
    ..Here, we report on the decision process for the case of a molecular genetics group establishing a microarray laboratory...
  2. pmc WormQTLHD--a web database for linking human disease to natural variation data in C. elegans
    K Joeri van der Velde
    Genomics Coordination Center, University of Groningen, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands, Groningen Bioinformatics Center, University of Groningen, P O Box 11103, 9700 CC Groningen, The Netherlands, Department of Genetics, University of Groningen, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands, Department of Bioinformatics, Hanze University of Applied Sciences, Groningen, Zernikeplein 11, 9747 AS, The Netherlands and Laboratory of Nematology, Wageningen University, 6708 PB Wageningen, The Netherlands
    Nucleic Acids Res 42:D794-801. 2014
    ..All software is available as open source, built on MOLGENIS and xQTL workbench. ..
  3. pmc xQTL workbench: a scalable web environment for multi-level QTL analysis
    Danny Arends
    Groningen Bioinformatics Centre, University of Groningen, Groningen, The Netherlands
    Bioinformatics 28:1042-4. 2012
    ..All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator...
  4. pmc designGG: an R-package and web tool for the optimal design of genetical genomics experiments
    Yang Li
    Groningen Bioinformatics Center, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    BMC Bioinformatics 10:188. 2009
    ..The optimal design of such genetical genomics experiments in a cost-efficient and effective way is not trivial...
  5. pmc Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans
    Yang Li
    Groningen Bioinformatics Centre, University of Groningen, 9751 NN, Haren, The Netherlands
    Genetics 186:405-10. 2010
    ..Our findings suggest that the regulatory mechanism of alternative splicing in C. elegans is robust toward genetic variation at the genome-wide scale, which is in striking contrast to earlier observations in humans...
  6. ncbi request reprint MetaNetwork: a computational protocol for the genetic study of metabolic networks
    Jingyuan Fu
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Protoc 2:685-94. 2007
    ..This way MetaNetwork will contribute to a better integration of such data into systems biology...
  7. pmc The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button
    Morris A Swertz
    Genomics Coordination Center, Groningen Bioinformatics Center, University of Groningen and Department of Genetics, University Medical Center Groningen, P O Box 30001, 9700 RB Groningen, The Netherlands
    BMC Bioinformatics 11:S12. 2010
    ..We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed...
  8. pmc XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
    Morris A Swertz
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Genome Biol 11:R27. 2010
    ..Current functionality includes tools ranging from eQTL analysis in mouse to genome-wide association studies in humans...
  9. doi request reprint PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis
    Richard A Scheltema
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands
    Anal Chem 83:2786-93. 2011
    ..The PeakML/mzMatch software is freely available at http://mzmatch.sourceforge.net, with documentation, tutorials, and a community forum...
  10. ncbi request reprint An overview and online registry of microvillus inclusion disease patients and their MYO5B mutations
    K Joeri van der Velde
    Genomics Coordination Center, Department of Genetics, University Medical Center Groningen, University of Groningen, The Netherlands
    Hum Mutat 34:1597-605. 2013
    ..The future expansion and prospective nature of this registry is expected to improve disease diagnosis, prognosis, and genetic counseling. ..
  11. doi request reprint A high-throughput processing service for retention time alignment of complex proteomics and metabolomics LC-MS data
    Isthiaq Ahmad
    Analytical Biochemistry, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Bioinformatics 27:1176-8. 2011
    ..Taverna workflow and command line tool are provided for remote processing of local user data...
  12. doi request reprint The international dystrophic epidermolysis bullosa patient registry: an online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations
    Peter C van den Akker
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hum Mutat 32:1100-7. 2011
    ..Altogether, this registry will greatly benefit the DEB patients...
  13. ncbi request reprint Beyond standardization: dynamic software infrastructures for systems biology
    Morris A Swertz
    Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
    Nat Rev Genet 8:235-43. 2007
    ..We argue that a minimal computer language, and a software tool called a generator, can be used to quickly produce customized software infrastructures that 'systems biologists really want to have'...
  14. ncbi request reprint Combining microarrays and genetic analysis
    Rudi Alberts
    Groningen Bioinformatics Centre, University of Groningen, Kerklaan 30, 9751 NN, Haren, The Netherlands
    Brief Bioinform 6:135-45. 2005
    ..It is shown how to fully exploit the power of genetics through optimal experimental design and analysis for two major microarray technologies, cDNA two-colour arrays and Affymetrix short oligonucleotide arrays...
  15. pmc Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms
    Tjakko J van Ham
    Department of Genetics, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    EMBO Mol Med 1:360-70. 2009
    ....