Guido W M Swart

Summary

Affiliation: University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Activated leukocyte cell adhesion molecule (CD166/ALCAM): developmental and mechanistic aspects of cell clustering and cell migration
    Guido W M Swart
    Department of Biochemistry, University of Nijmegen, The Netherlands
    Eur J Cell Biol 81:313-21. 2002
  2. ncbi request reprint International Melanoma Research Congress--Foundation for Melanoma Research. 21-24 June 2003, Philadelphia, PA, USA
    Guido W M Swart
    161 Department of Biochemistry, Nijmegen Center for Molecular Life Sciences, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    IDrugs 6:752-4. 2003
  3. ncbi request reprint Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis
    Leon C L T van Kempen
    Department of Biochemistry NCMLS, University of Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 122:1293-301. 2004
  4. ncbi request reprint Multiple complementary transcripts of pCMa1, a novel gene located at chromosome 11p15.1-2, and melanocytic cell transformation
    Clifton B Meije
    Department of Biochemistry, University of Nijmegen, The Netherlands
    J Pathol 197:668-76. 2002
  5. ncbi request reprint Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?
    Guido W M Swart
    Department of Biochemistry, Science Faculty, Radboud University Nijmegen, Nijmegen, Netherlands
    Cancer Metastasis Rev 24:223-36. 2005
  6. ncbi request reprint Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity
    Pim C Lunter
    Department of Biochemistry 161, Nijmegen Center of Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
    Cancer Res 65:8801-8. 2005
  7. doi request reprint Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry 271, Institute for Molecules and Materials and Nijmegen Centre for Molecular Life Sciences, Faculty of Science, Radboud University Nijmegen
    Cancer Res 68:3671-9. 2008
  8. ncbi request reprint Gene expression patterns in melanocytic cells: candidate markers for early stage and malignant transformation
    Clifton B Meije
    Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    J Pathol 196:51-8. 2002

Collaborators

  • Claus Garbe
  • MEENHARD I HERLYN
  • F Meier
  • Jeroen W J van Kilsdonk
  • Clifton B Meije
  • Goos N P Van Muijen
  • Leon C L T van Kempen
  • Mieke Bergers
  • Pim C Lunter
  • Ulrich H Weidle
  • Wouter H Lamers
  • Theodorus B M Hakvoort
  • Pranab K Das
  • Roel H Wilting
  • Joost Schalkwijk
  • Hanneke van Beek
  • Ine M H A Cornelissen
  • Peter H G M Willems
  • Monique J F Kersten-Niessen
  • Mikala Egeblad
  • Henri P J Bloemers
  • Allard C van der Wal
  • Chi Hau
  • Wiete Westerhof
  • Miranda M E Jans
  • Marielle Alders

Detail Information

Publications8

  1. ncbi request reprint Activated leukocyte cell adhesion molecule (CD166/ALCAM): developmental and mechanistic aspects of cell clustering and cell migration
    Guido W M Swart
    Department of Biochemistry, University of Nijmegen, The Netherlands
    Eur J Cell Biol 81:313-21. 2002
    ..Accumulating evidence suggests that ALCAM expression may reflect the onset of a cellular program for homeostatic control of growth saturation, which induces either growth arrest or cell migration when the upper limits are exceeded...
  2. ncbi request reprint International Melanoma Research Congress--Foundation for Melanoma Research. 21-24 June 2003, Philadelphia, PA, USA
    Guido W M Swart
    161 Department of Biochemistry, Nijmegen Center for Molecular Life Sciences, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    IDrugs 6:752-4. 2003
  3. ncbi request reprint Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis
    Leon C L T van Kempen
    Department of Biochemistry NCMLS, University of Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 122:1293-301. 2004
    ..ALCAM induction could, thus, provide an attractive target for proteolysis as a part of a more complex cellular program that couples growth and migration and facilitates dissemination...
  4. ncbi request reprint Multiple complementary transcripts of pCMa1, a novel gene located at chromosome 11p15.1-2, and melanocytic cell transformation
    Clifton B Meije
    Department of Biochemistry, University of Nijmegen, The Netherlands
    J Pathol 197:668-76. 2002
    ....
  5. ncbi request reprint Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?
    Guido W M Swart
    Department of Biochemistry, Science Faculty, Radboud University Nijmegen, Nijmegen, Netherlands
    Cancer Metastasis Rev 24:223-36. 2005
    ..It is hypothesized that ALCAM may function as a cell surface sensor to register local growth saturation and to regulate cellular signaling and dynamic responses...
  6. ncbi request reprint Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity
    Pim C Lunter
    Department of Biochemistry 161, Nijmegen Center of Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
    Cancer Res 65:8801-8. 2005
    ..These data attribute a novel signaling role to ALCAM in regulation of proteolysis and support its previously postulated sensor function in invasive growth...
  7. doi request reprint Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry 271, Institute for Molecules and Materials and Nijmegen Centre for Molecular Life Sciences, Faculty of Science, Radboud University Nijmegen
    Cancer Res 68:3671-9. 2008
    ....
  8. ncbi request reprint Gene expression patterns in melanocytic cells: candidate markers for early stage and malignant transformation
    Clifton B Meije
    Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    J Pathol 196:51-8. 2002
    ..The Ras-related protein Rab5b showed lower levels of expression in highly metastatic than in other melanoma cells. These three cDNAs may therefore be involved in the early stage and malignant transformation of melanocytes...