Ruzena Stranska

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi request reprint Routine use of a highly automated and internally controlled real-time PCR assay for the diagnosis of herpes simplex and varicella-zoster virus infections
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Clin Virol 30:39-44. 2004
  2. pmc ELVIRA HSV, a yield reduction assay for rapid herpes simplex virus susceptibility testing
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Antimicrob Agents Chemother 48:2331-3. 2004
  3. ncbi request reprint Genotypic and phenotypic characterization of acyclovir-resistant herpes simplex viruses isolated from haematopoietic stem cell transplant recipients
    Ruzena Stranska
    Department of Virology, University Medical Centre Utrecht, The Netherlands
    Antivir Ther 9:565-75. 2004
  4. ncbi request reprint Survey of acyclovir-resistant herpes simplex virus in the Netherlands: prevalence and characterization
    Ruzena Stranska
    Department of Virology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    J Clin Virol 32:7-18. 2005
  5. pmc Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, The Netherlands
    Antimicrob Agents Chemother 46:2943-7. 2002
  6. ncbi request reprint Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    Int J Antimicrob Agents 25:419-26. 2005
  7. ncbi request reprint Sequential switching of DNA polymerase and thymidine kinase-mediated HSV-1 drug resistance in an immunocompromised child
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, The Netherlands
    Antivir Ther 9:97-104. 2004

Detail Information

Publications7

  1. ncbi request reprint Routine use of a highly automated and internally controlled real-time PCR assay for the diagnosis of herpes simplex and varicella-zoster virus infections
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Clin Virol 30:39-44. 2004
    ..The development of real-time PCR, which has overcome several limitations of conventional PCR, improved the prospects for implementation of PCR-based assays in diagnostic laboratory...
  2. pmc ELVIRA HSV, a yield reduction assay for rapid herpes simplex virus susceptibility testing
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Antimicrob Agents Chemother 48:2331-3. 2004
    ..It uses an HSV-inducible reporter cell line. This simple and rapid assay has an objective readout, low inoculum size, and good reproducibility. The results correlate well with those of the plaque reduction assay...
  3. ncbi request reprint Genotypic and phenotypic characterization of acyclovir-resistant herpes simplex viruses isolated from haematopoietic stem cell transplant recipients
    Ruzena Stranska
    Department of Virology, University Medical Centre Utrecht, The Netherlands
    Antivir Ther 9:565-75. 2004
    ..Our study confirms and expands previous data on genotypic changes associated with ACV resistance of HSV-1 clinical isolates...
  4. ncbi request reprint Survey of acyclovir-resistant herpes simplex virus in the Netherlands: prevalence and characterization
    Ruzena Stranska
    Department of Virology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    J Clin Virol 32:7-18. 2005
    ..Widespread and frequent use of acyclovir (ACV) for treatment, suppressive therapy and prophylaxis of herpes simplex virus (HSV) infections and its over the counter availability may be associated with emergence of HSV resistance...
  5. pmc Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, The Netherlands
    Antimicrob Agents Chemother 46:2943-7. 2002
    ..In conclusion, the real-time PCR assay described here is a suitable quantitative method for determination of antiviral susceptibility of HSV-1, amenable for use in the routine diagnostic virology laboratory...
  6. ncbi request reprint Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    Int J Antimicrob Agents 25:419-26. 2005
    ..These results suggest that APHS is a NNRTI of HIV-1 replication, but not HIV-2 replication, and that APHS is an inhibitor of both HSV-1 and HSV-2 replication...
  7. ncbi request reprint Sequential switching of DNA polymerase and thymidine kinase-mediated HSV-1 drug resistance in an immunocompromised child
    Ruzena Stranska
    Department of Virology, Eijkman Winkler Center, University Medical Center Utrecht, The Netherlands
    Antivir Ther 9:97-104. 2004
    ....