Ronald P Stolk

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi request reprint Gender differences in predictors of the decline of renal function in the general population
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Kidney Int 74:505-12. 2008
  2. pmc Population ageing research: a family of disciplines
    Ronald P Stolk
    Healthy Ageing Population and Society HAPS, University of Groningen, Groningen, The Netherlands
    Eur J Epidemiol 24:715-8. 2009
  3. doi request reprint Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, P O Box 30 001, 9700RB Groningen, The Netherlands
    Diabetes Care 31:708-13. 2008
  4. ncbi request reprint Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Epidemiol 23:67-74. 2008
  5. ncbi request reprint Rationale and design of the AdRem study: evaluating the effects of blood pressure lowering and intensive glucose control on vascular retinal disorders in patients with type 2 diabetes mellitus
    Ronald P Stolk
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Contemp Clin Trials 28:6-17. 2007
  6. doi request reprint Development and validation of a general population renal risk score
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, University Hospital Groningen, Groningen, The Netherlands
    Clin J Am Soc Nephrol 6:1731-8. 2011
  7. doi request reprint External validation of the KORA S4/F4 prediction models for the risk of developing type 2 diabetes in older adults: the PREVEND study
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Eur J Epidemiol 27:47-52. 2012
  8. ncbi request reprint Patient characteristics do not predict poor glycaemic control in type 2 diabetes patients treated in primary care
    Alex N Goudswaard
    Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
    Eur J Epidemiol 19:541-5. 2004
  9. pmc Liver function tests and risk prediction of incident type 2 diabetes: evaluation in two independent cohorts
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    PLoS ONE 7:e51496. 2012
  10. ncbi request reprint Changes in renal risk factors versus renal function outcome during follow-up in a population-based cohort study
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen UMCG, University of Groningen, Groningen, The Netherlands
    Nephrol Dial Transplant 25:1846-53. 2010

Detail Information

Publications87

  1. ncbi request reprint Gender differences in predictors of the decline of renal function in the general population
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Kidney Int 74:505-12. 2008
    ..These studies show that there are gender differences in the standard predictors of the decline in renal function...
  2. pmc Population ageing research: a family of disciplines
    Ronald P Stolk
    Healthy Ageing Population and Society HAPS, University of Groningen, Groningen, The Netherlands
    Eur J Epidemiol 24:715-8. 2009
    ....
  3. doi request reprint Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, P O Box 30 001, 9700RB Groningen, The Netherlands
    Diabetes Care 31:708-13. 2008
    ....
  4. ncbi request reprint Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Epidemiol 23:67-74. 2008
    ..LifeLines will contribute to the understanding of how universal risk factors are modified to influence the individual susceptibility to multifactorial diseases, not only at one stage of life but cumulatively over time: the lifeline...
  5. ncbi request reprint Rationale and design of the AdRem study: evaluating the effects of blood pressure lowering and intensive glucose control on vascular retinal disorders in patients with type 2 diabetes mellitus
    Ronald P Stolk
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Contemp Clin Trials 28:6-17. 2007
    ....
  6. doi request reprint Development and validation of a general population renal risk score
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, University Hospital Groningen, Groningen, The Netherlands
    Clin J Am Soc Nephrol 6:1731-8. 2011
    ..73 m² during follow-up were defined as having progressive CKD. Possible predictors for progressive CKD were selected on the basis of univariable logistic regression analyses...
  7. doi request reprint External validation of the KORA S4/F4 prediction models for the risk of developing type 2 diabetes in older adults: the PREVEND study
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Eur J Epidemiol 27:47-52. 2012
    ..However, the models need to be corrected for intercept and slope to acquire good calibration for application in a different setting...
  8. ncbi request reprint Patient characteristics do not predict poor glycaemic control in type 2 diabetes patients treated in primary care
    Alex N Goudswaard
    Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
    Eur J Epidemiol 19:541-5. 2004
    ..Providers of diabetes care should be attentive to patients with lower educational level...
  9. pmc Liver function tests and risk prediction of incident type 2 diabetes: evaluation in two independent cohorts
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    PLoS ONE 7:e51496. 2012
    ..Liver function tests might predict the risk of type 2 diabetes. An independent study evaluating utility of these markers compared with an existing prediction model is yet lacking...
  10. ncbi request reprint Changes in renal risk factors versus renal function outcome during follow-up in a population-based cohort study
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen UMCG, University of Groningen, Groningen, The Netherlands
    Nephrol Dial Transplant 25:1846-53. 2010
    ..Therefore, the aim of this study was to investigate whether besides the baseline values of these risk factors, changes in risk factors are associated with subsequent rate of renal function loss...
  11. pmc Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands
    BMJ 345:e5900. 2012
    ..To identify existing prediction models for the risk of development of type 2 diabetes and to externally validate them in a large independent cohort...
  12. ncbi request reprint Refill adherence and polypharmacy among patients with type 2 diabetes in general practice
    Rykel van Bruggen
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 18:983-91. 2009
    ..This study aims to investigate the occurrence of polypharmacy and non-adherence in general practice, their mutual relationship and the association between adherence and the intermediate outcomes of diabetes care...
  13. pmc MRI-determined fat content of human liver, pancreas and kidney
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    World J Gastroenterol 16:1993-8. 2010
    ..To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight...
  14. doi request reprint Parental history of type 2 diabetes and cardiometabolic biomarkers in offspring
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Eur J Clin Invest 42:974-82. 2012
    ..We aimed to investigate the associations of parental history of T2D with cardiometabolic biomarkers and to subsequently investigate to what extent these putative associations were explained by modifiable factors...
  15. pmc Differential effects of comorbidity on antihypertensive and glucose-regulating treatment in diabetes mellitus--a cohort study
    Jaco Voorham
    Department of Clinical Pharmacology, Faculty of Medical Science, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 7:e38707. 2012
    ..We hypothesized that these effects differ according to expected priority of the conditions...
  16. pmc Three years follow-up of screen-detected diabetic and non-diabetic subjects: who is better off? The ADDITION Netherlands study
    Paul G H Janssen
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    BMC Fam Pract 9:67. 2008
    ..Our aim was to determine the extent of health care utilization and provision in primary care and to evaluate the risk of cardiovascular disease in persons with an elevated risk score in a stepwise diabetes screening programme...
  17. doi request reprint Escherichia coli bacteriuria in female adults is associated with the development of hypertension
    Ruby Meiland
    Department of Infectious Diseases and AIDS, UMC Utrecht, Utrecht, The Netherlands
    Int J Infect Dis 14:e304-7. 2010
    ..To investigate whether Escherichia coli bacteriuria is associated with the development of hypertension during a long-term follow-up...
  18. pmc Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    J Am Heart Assoc 1:e002956. 2012
    ..We subsequently examined the incremental value of Prx4 for the risk prediction of CVD compared with the Framingham risk score (FRS)...
  19. doi request reprint Screen detected subjects with type 2 diabetes and impaired glucose tolerance have more adverse cardiovascular risk than subjects with impaired fasting glucose especially when they are obese: the ADDITION Netherlands study
    Paul G H Janssen
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Prim Care Diabetes 1:69-74. 2007
    ..To examine whether BMI is an effect modifier regarding the relation between level of glucose regulation and cardiovascular risk factors...
  20. ncbi request reprint High dietary glycemic load and glycemic index increase risk of cardiovascular disease among middle-aged women: a population-based follow-up study
    Joline W J Beulens
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Am Coll Cardiol 50:14-21. 2007
    ..The goal of this work was to assess whether high dietary glycemic load and glycemic index are associated with an increased risk of cardiovascular disease (CVD)...
  21. pmc Differences in the pattern of antibiotic prescription profile and recurrence rate for possible urinary tract infections in women with and without diabetes
    Caroline Schneeberger
    Department of Epidemiology, University Medical Center Groningen, Amsterdam, The Netherlands
    Diabetes Care 31:1380-5. 2008
    ..Women with diabetes have a high incidence and complication rate of urinary tract infections (UTIs). Our aims were to compare current treatment strategies with respect to recurrence rates in women with diabetes with those without diabetes...
  22. pmc Randomised controlled trial of intensive multifactorial treatment for cardiovascular risk in patients with screen-detected type 2 diabetes: 1-year data from the ADDITION Netherlands study
    Paul Gh Janssen
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Br J Gen Pract 59:43-8. 2009
    ..A growing body of evidence suggests that earlier diagnosis and treatment of diabetes may be beneficial; however, definitive evidence is lacking...
  23. ncbi request reprint Determinants of daily insulin use in Type 1 diabetes
    Marian J Muis
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Department of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
    J Diabetes Complications 20:356-60. 2006
    ..Insulin need for a given degree of glucose control varies markedly among individuals. We examined which factors determine daily insulin use in patients with Type 1 diabetes...
  24. doi request reprint Medication adherence affects treatment modifications in patients with type 2 diabetes
    Jaco Voorham
    Department of Clinical Pharmacology, Faculty of Medical Science, University Medical Center Groningen, University of Groningen, The Netherlands
    Clin Ther 33:121-34. 2011
    ..Although adherence problems are often mentioned in surveys as a reason for not intensifying treatment, observational studies have shown inconclusive results...
  25. pmc Low physical activity and risk of cardiovascular and all-cause mortality in renal transplant recipients
    Dorien M Zelle
    Department of Nephrology, University Medical Center Groningen, Sector A, PO Box 30001, 9700 RB, Groningen, The Netherlands
    Clin J Am Soc Nephrol 6:898-905. 2011
    ..This is largely unexplored in renal transplant recipients (RTRs). We studied whether PA is associated with cardiovascular and all-cause mortality in a prospective cohort of RTR...
  26. ncbi request reprint Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents' Individual Lives Survey) Study
    Eryn T Liem
    Department of Pediatrics Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
    Am J Clin Nutr 91:321-8. 2010
    ..Overweight is a complex trait in which both environmental and genetic factors play a role...
  27. ncbi request reprint Influence of elevated cardiometabolic risk factor levels on treatment changes in type 2 diabetes
    Jaco Voorham
    Clinical Pharmacology, University of Groningen, Groningen, The Netherlands
    Diabetes Care 31:501-3. 2008
    ..The low overall action rates observed for blood pressure and especially lipid management cannot sufficiently be explained by the use of treatment thresholds higher than those indicated by guidelines...
  28. pmc Circulating peroxiredoxin 4 and type 2 diabetes risk: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study
    Ali Abbasi
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Diabetologia 57:1842-9. 2014
    ..We previously showed that the circulating antioxidant peroxiredoxin 4 (Prx4) is associated with cardiometabolic risk factors. We aimed to evaluate the association of Prx4 with type 2 diabetes risk in the general population...
  29. doi request reprint Insulin resistance and cardiovascular risk factors in 3- to 5-year-old overweight or obese children
    Gianni Bocca
    Department of Pediatrics, Beatrix Children s Hospital, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands
    Horm Res Paediatr 80:201-6. 2013
    ..The complications of overweight and obesity at a young age are largely unknown. We aimed to assess the prevalence of insulin resistance (IR) and cardiovascular risk factors among overweight and obese children aged 3-5 years...
  30. ncbi request reprint Common cholesteryl ester transfer protein gene polymorphisms and the effect of atorvastatin therapy in type 2 diabetes
    Francine V van Venrooij
    Department of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
    Diabetes Care 26:1216-23. 2003
    ..The cholesteryl ester transfer protein (CETP) plays a key role in the remodeling of triglyceride (TG)-rich and HDL particles. Sequence variations in the CETP gene may interfere with the effect of lipid-lowering treatment in type 2 diabetes...
  31. pmc Pancreatic β-cell dysfunction and risk of new-onset diabetes after kidney transplantation
    Dorien M Zelle
    Department of Nephrology, University Medical Center Groningen, Groningen, The Netherlands
    Diabetes Care 36:1926-32. 2013
    ..Therefore, we prospectively investigated whether proinsulin, as a marker of pancreatic β-cell dysfunction, is associated with future development of NODAT and improves prediction of it...
  32. doi request reprint Role of HDL cholesterol and estimates of HDL particle composition in future development of type 2 diabetes in the general population: the PREVEND study
    Ali Abbasi
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, The Netherlands
    J Clin Endocrinol Metab 98:E1352-9. 2013
    ....
  33. ncbi request reprint Antipsychotic drugs may worsen metabolic control in type 2 diabetes mellitus
    José A Spoelstra
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Clin Psychiatry 65:674-8. 2004
    ..In this study, we investigated whether the use of antipsychotic drugs in patients with diabetes leads to worsening of glycemic control...
  34. ncbi request reprint Plasma procalcitonin is associated with obesity, insulin resistance, and the metabolic syndrome
    Ali Abbasi
    Department of Epidemiology, University Medical Center Groningen, Hanzeplein 1, PO Box 30 001, 9700 RB Groningen, The Netherlands
    J Clin Endocrinol Metab 95:E26-31. 2010
    ..Procalcitonin, a well-known biomarker of sepsis and bacterial infections, is produced by adipose tissue and has potential as a marker for chronic low-grade inflammation...
  35. ncbi request reprint Comparison of methods to assess body fat in non-obese six to seven-year-old children
    Carianne L'Abée
    Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands
    Clin Nutr 29:317-22. 2010
    ..No data are available on the estimation of total body fat in non-obese children. The aim of this study is to compare total body fat, assessed by different methods in non-obese children...
  36. ncbi request reprint Asymptomatic bacteriuria in women with diabetes mellitus: effect on renal function after 6 years of follow-up
    Ruby Meiland
    Department of Internal Medicine and Infectious Diseases, Eijman Winkler Center for Microbiology and Infectious Diseases, Utrecht, The Netherlands
    Arch Intern Med 166:2222-7. 2006
    ..The long-term consequences of asymptomatic bacteriuria (ASB) on renal function in women with diabetes mellitus (DM) are unknown...
  37. ncbi request reprint Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns
    Mariken de Krom
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Diabetes 56:276-80. 2007
    ..In conclusion, we identified common allelic variants specifically associated with distinctly different eating patterns, namely extreme snacking behavior or excessive portion size...
  38. ncbi request reprint The bioelectrical impedance vector migration in healthy infants
    Carianne L'Abée
    Department of Pediatrics, University Medical Center Groningen, University of Groningen, The Netherlands
    Clin Nutr 29:222-6. 2010
    ..Detecting young children with high amount of body fat is important to intervene in the development of obesity. The aim of this study is to gain inside in the bioelectrical impedance vector analysis in healthy infants...
  39. doi request reprint Motorized transportation, social status, and adiposity: the China Health and Nutrition Survey
    Li Qin
    Department of Epidemiology, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands
    Am J Prev Med 43:1-10. 2012
    ..Increased dependence on motorized transportation may contribute to obesity. Countries in rapid socioeconomic transitions, such as China, provide an opportunity to investigate such an association...
  40. doi request reprint Predictors for starting depot administration of risperidone in chronic users of antipsychotics
    Jelle Vehof
    Department of Epidemiology, University Medical Center Groningen, The Netherlands
    J Clin Psychopharmacol 28:625-30. 2008
    ..Thereafter, questions about the type of patients actually treated with RLAI in daily practice remain to be answered for making valid antipsychotic treatment comparisons involving RLAI in observational studies...
  41. pmc High protein intake associates with cardiovascular events but not with loss of renal function
    Nynke Halbesma
    Division of Nephrology, Department of Medicine, University Medical Center Groningen, University Hospital Groningen, Groningen, Netherlands
    J Am Soc Nephrol 20:1797-804. 2009
    ..In summary, in the general population, high protein intake does not promote accelerated decline of renal function but does associate with an increased risk for cardiovascular events...
  42. ncbi request reprint Alcohol consumption and risk of type 2 diabetes among older women
    Joline W J Beulens
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    Diabetes Care 28:2933-8. 2005
    ..This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women...
  43. pmc Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci
    Vinicius Tragante
    Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands Department of Medical Genetics, Biomedical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Am J Hum Genet 94:349-60. 2014
    ..In summary, we identified previously unknown loci associated with BP. Our findings extend our understanding of genes involved in BP regulation, which may provide new targets for therapeutic intervention or drug response stratification...
  44. doi request reprint The role of fitness in the association between fatness and cardiometabolic risk from childhood to adolescence
    Silvia I Brouwer
    Hanze University of Applied Sciences Groningen, School of Sport studies, Groningen, 9747, The Netherlands
    Pediatr Diabetes 14:57-65. 2013
    ..Fatness and fitness both influence cardiometabolic risk...
  45. doi request reprint Is directly measured physical activity related to adiposity in preschool children?
    Anna Sijtsma
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
    Int J Pediatr Obes 6:389-400. 2011
    ..Further studies using directly measured physical activity and percentage body fat to define adiposity are needed to draw more firm conclusions...
  46. pmc Physical activity, adiposity, and diabetes risk in middle-aged and older Chinese population: the Guangzhou Biobank Cohort Study
    Li Qin
    Department of Epidemiology, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands
    Diabetes Care 33:2342-8. 2010
    ..We investigated the independent and joint association of adiposity and physical activity with fasting plasma glucose, impaired fasting glucose, and type 2 diabetes in a Chinese population...
  47. pmc Do characteristics of practices and general practitioners influence the yield of diabetes screening in primary care? The ADDITION Netherlands study
    Paul G H Janssen
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Scand J Prim Health Care 26:160-5. 2008
    ..To investigate whether the yield of population-based diabetes screening is influenced by characteristics of the general practitioner (GP) and the practice...
  48. ncbi request reprint Association between Escherichia coli bacteriuria and renal function in women: long-term follow-up
    Ruby Meiland
    Department of Internal Medicine and Infectious Diseases, University Medical Center, Utrecht, The Netherlands
    Arch Intern Med 167:253-7. 2007
    ..We sought to investigate whether Escherichia coli bacteriuria is associated with a decline in renal function or with the development of end-stage renal failure after long-term follow-up...
  49. doi request reprint Association between depressive symptoms in childhood and adolescence and overweight in later life: review of the recent literature
    Eryn T Liem
    Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Arch Pediatr Adolesc Med 162:981-8. 2008
    ..To present an overview of the association between depressive symptoms in childhood and adolescence and subsequent overweight in later life...
  50. pmc HbA1c in nondiabetic Dutch infants aged 8-12 months: the GECKO-Drenthe birth cohort study
    Hanneke Jansen
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Diabetes Care 34:403-5. 2011
    ..Little is known about normal values of HbA(1c) in infants. The aim of this study is to describe the distribution of HbA(1c) in 8- to 12-month-old nondiabetic infants...
  51. pmc Does physical activity modify the risk of obesity for type 2 diabetes: a review of epidemiological data
    Li Qin
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, P O Box 30 001, 9700, RB, Groningen, The Netherlands
    Eur J Epidemiol 25:5-12. 2010
    ..Furthermore, this review clearly showed that results can differ depending on what method is used to assess interaction...
  52. doi request reprint Obesity and impaired renal function: potential for lifestyle intervention?
    Eva Corpeleijn
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Epidemiol 24:275-80. 2009
    ..After the recent success of lifestyle intervention to prevent diabetes, further research is needed to show the effects of lifestyle changes to prevent and reduce obesity-related morbidity, including chronic kidney disease...
  53. doi request reprint Causal inference algorithms can be useful in life course epidemiology
    Sacha La Bastide-Van Gemert
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, PO Box 30 001, 9700 RB Groningen, The Netherlands Electronic address
    J Clin Epidemiol 67:190-8. 2014
    ..This article explains the theoretical concepts of the search algorithms used for finding such representations, discusses various types of such algorithms, and exemplifies their use in the context of obesity and insulin resistance...
  54. doi request reprint Infant movement opportunities are related to early growth--GECKO Drenthe cohort
    Anna Sijtsma
    Department of Epidemiology of the University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Early Hum Dev 89:457-61. 2013
    ..Movement by an infant during the first year of life might influence its activity level and thereby influence growth in early childhood...
  55. doi request reprint Growth during infancy and childhood, and adiposity at age 16 years: ages 2 to 7 years are pivotal
    Eryn T Liem
    Department of Pediatrics, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Pediatr 162:287-92.e2. 2013
    ..To assess the period during infancy and childhood in which growth is most associated with adolescent adiposity and the metabolic syndrome (MS) and whether this differs depending on maternal smoking during pregnancy...
  56. doi request reprint Results of a multidisciplinary treatment program in 3-year-old to 5-year-old overweight or obese children: a randomized controlled clinical trial
    Gianni Bocca
    Department of Pediatrics, Beatrix Children s Hospital, Groningen, The Netherlands
    Arch Pediatr Adolesc Med 166:1109-15. 2012
    ..To assess the effects of a multidisciplinary intervention program for 3-year-old to 5-year-old overweight and obese children compared with a usual-care program...
  57. pmc The LIFESTYLE study: costs and effects of a structured lifestyle program in overweight and obese subfertile women to reduce the need for fertility treatment and improve reproductive outcome. A randomised controlled trial
    Meike A Q Mutsaerts
    Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    BMC Womens Health 10:22. 2010
    ..We hypothesize that the intervention will decrease the need for fertility treatment, diminish overweight-related pregnancy complications, and will improve perinatal outcome...
  58. pmc PRegnancy Outcomes after a Maternity Intervention for Stressful EmotionS (PROMISES): study protocol for a randomised controlled trial
    Judith L Meijer
    Department of Epidemiology, University Medical Centre Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands
    Trials 12:157. 2011
    ..In addition, we aim to study its effects on the child's development, maternal mental health, and neonatal outcomes, as well as the cost-effectiveness of cognitive behavioural therapy relative to usual care...
  59. doi request reprint Ultrasonography to quantify hepatic fat content: validation by 1H magnetic resonance spectroscopy
    Mireille A Edens
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Obesity (Silver Spring) 17:2239-44. 2009
    ..001). This validation study shows that a combination of computer-assessed ultrasound measures from routine ultrasound images can be used to quantitatively assess hepatic fat content...
  60. ncbi request reprint Starting insulin in type 2 diabetes: continue oral hypoglycemic agents? A randomized trial in primary care
    Alex N Goudswaard
    University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Koperslagersgilde 5, 3994 CH Houten, The Netherlands
    J Fam Pract 53:393-9. 2004
    ..To evaluate the effects of insulin 30/70 twice daily or bedtime isophane (NPH) insulin plus continued sulfonylurea and metformin in patients with type 2 diabetes in primary care...
  61. ncbi request reprint Associations of life events during pregnancy with longitudinal change in symptoms of antenatal anxiety and depression
    Judith L Meijer
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Midwifery 30:526-31. 2014
    ..In addition, we investigated whether the associations were affected by personality or childhood adversities...
  62. pmc Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci
    Folkert W Asselbergs
    Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Hum Genet 91:823-38. 2012
    ..The explained phenotypic variance from this approach was comparable to that from a meta-analysis of GWAS data, suggesting that a focused genotyping approach can further increase the understanding of heritability of plasma lipids...
  63. doi request reprint Cohort Profile: the GECKO Drenthe study, overweight programming during early childhood
    Carianne L'Abée
    Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Int J Epidemiol 37:486-9. 2008
  64. ncbi request reprint Vitamin D deficiency: universal risk factor for multifactorial diseases?
    Martin H de Borst
    Departments of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Curr Drug Targets 12:97-106. 2011
    ..Further exploration of the multifaceted actions of vitamin D may pave the way for disease-overriding intervention strategies...
  65. ncbi request reprint Antihypertensive drug therapy and the risk of lower extremity amputations in pharmacologically treated type 2 diabetes patients
    Joelle A Erkens
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 13:139-46. 2004
    ..The objective of this study was to determine the association between different antihypertensive drug therapies and lower extremity amputations (LEAs) in type 2 diabetes patients...
  66. pmc Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial
    Janna M Munster
    University of Groningen, University Centre for Pharmacy, Pharmacoepidemiology and Pharmacoeconomics, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    BMC Womens Health 10:32. 2010
    ..We designed a trial to assess the (cost-)effectiveness of a screening program for Q fever in pregnant women living in risks areas in The Netherlands...
  67. ncbi request reprint Abdominal fat and risk of coronary heart disease in patients with peripheral arterial disease
    Beate G Brouwer
    University Medical Center Utrecht, Room strat 6 131, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Obesity (Silver Spring) 15:1623-30. 2007
    ....
  68. ncbi request reprint Accident proneness, does it exist? A review and meta-analysis
    Ellen Visser
    Department of Psychiatry, University Medical Center Groningen, Department of Psychiatry, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Accid Anal Prev 39:556-64. 2007
    ..In an effort to reach professional consensus on the concept, we end this paper with recommendations for further research...
  69. doi request reprint Parental factors affecting the weights of the placenta and the offspring
    Carianne L'Abée
    Department of Pediatrics, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
    J Perinat Med 39:27-34. 2011
    ..To determine parental, especially paternal factors associated with the weight of the placenta and offspring...
  70. ncbi request reprint Ultrasound measurements of intraabdominal fat estimate the metabolic syndrome better than do measurements of waist circumference
    Ronald P Stolk
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Netherlands
    Am J Clin Nutr 77:857-60. 2003
    ..This method is more accurate than measurement of waist and hip circumferences and is simpler and less expensive than computed tomography or magnetic resonance imaging...
  71. ncbi request reprint History taking and leukocyturia predict the presence of asymptomatic bacteriuria in women with diabetes mellitus
    Ruby Meiland
    Department of Medicine, Division Acute Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Epidemiol 19:1021-7. 2004
    ..To investigate the accuracy of history taking to diagnose asymptomatic bacteriuria (ASB) in diabetic women, and the added value of leukocyturia...
  72. doi request reprint Comparison of frequency of periprocedural myocardial infarction in patients with and without diabetes mellitus to those with previously unknown but elevated glycated hemoglobin levels (from the TWENTE Trial)
    Kenneth Tandjung
    Department of Cardiology, Thoraxcentrum, Twente, The Netherlands, and Medisch Spectrum Twente, Enschede, The Netherlands
    Am J Cardiol 110:1561-7. 2012
    ..6% vs 8.0%, p = 0.25). In conclusion, undetected diabetics were shown to have an increased risk of PMI...
  73. pmc The analysis of longitudinal quality of life measures with informative drop-out: a pattern mixture approach
    Wendy J Post
    Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands
    Qual Life Res 19:137-48. 2010
    ..Random effects models assume Missing At Random and do not take into account informative drop-out. We therefore aim to correct the bias due to informative drop-out...
  74. ncbi request reprint Quality of recording of data from patients with type 2 diabetes is not a valid indicator of quality of care. A cross-sectional study
    Alex N Goudswaard
    Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
    Fam Pract 20:173-7. 2003
    ..The quality of recording of clinical data in diabetes care in general practices is very variable. It has been suggested that better recording leads to improved glycaemic control...
  75. ncbi request reprint Aggressive lipid lowering does not improve endothelial function in type 2 diabetes: the Diabetes Atorvastatin Lipid Intervention (DALI) Study: a randomized, double-blind, placebo-controlled trial
    Francine V van Venrooij
    Julius Center for General Practice and Patient Oriented Research and Department of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
    Diabetes Care 25:1211-6. 2002
    ..Type 2 diabetic patients show a characteristic dyslipidemia. Aggressive lipid lowering might be an effective method to improve endothelial function in these patients...
  76. ncbi request reprint Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes
    W Ken Redekop
    Institute for Medical Technology Assessment iMTA, Erasmus University, Rotterdam, The Netherlands
    Diabetes Care 25:458-63. 2002
    ....
  77. ncbi request reprint The prevalence and management of diabetes in Thai adults: the international collaborative study of cardiovascular disease in Asia
    Wichai Aekplakorn
    Community Medicine Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Diabetes Care 26:2758-63. 2003
    ..The aim of this study was to determine in Thai adults aged >or=35 years the prevalence and management of diabetes and the associations of diabetes with cardiovascular risk factors...
  78. ncbi request reprint Are retinal microvascular abnormalities associated with large artery endothelial dysfunction and intima-media thickness? The Hoorn Study
    Manon V Van Hecke
    Department of Ophthalmology, VU University Medical Center, Amsterdam, The Netherlands
    Clin Sci (Lond) 110:597-604. 2006
    ..Therefore our data provide evidence that retinal microvascular disease is of limited value in risk stratification for future cardiovascular events...
  79. ncbi request reprint Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study
    Manon V Van Hecke
    Department of Ophthalmology, VU University Medical Center, 1007 MB Amsterdam, The Netherlands
    Clin Sci (Lond) 114:479-87. 2008
    ....
  80. ncbi request reprint Hyperglycemia and diabetes in patients with schizophrenia or schizoaffective disorders
    Dan Cohen
    Centre for Mental Health Care Rijngeestgroep, Noordwijkerhout, The Netherlands
    Diabetes Care 29:786-91. 2006
    ..To address this issue, we decided to assess glucose metabolism in a population of patients with schizophrenia or schizoaffective disorder...
  81. ncbi request reprint Refill compliance in type 2 diabetes mellitus: a predictor of switching to insulin therapy?
    José A Spoelstra
    Julius Center for General Practice and Patient Oriented Research, University Medical Center Utrecht, HP D01 335, PO Box 85500, 3508 GA Utrecht, Netherlands
    Pharmacoepidemiol Drug Saf 12:121-7. 2003
    ..To assess whether switching to insulin therapy in patients with type 2 diabetes mellitus is associated with medication refill compliance of oral hypoglycemic agents...
  82. ncbi request reprint High cumulative insulin exposure: a risk factor of atherosclerosis in type 1 diabetes?
    Marian J Muis
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Atherosclerosis 181:185-92. 2005
    ..We have focused on patients with type 1 diabetes instead of type 2 diabetes to minimise the effect of insulin resistance as a potential confounder...
  83. ncbi request reprint Cardiovascular risk factors and diseases precede oral hypoglycaemic therapy in patients with type 2 diabetes mellitus
    Joelle A Erkens
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, Netherlands
    J Clin Epidemiol 55:345-9. 2002
    ....
  84. ncbi request reprint Atorvastatin dose-dependently decreases hepatic lipase activity in type 2 diabetes: effect of sex and the LIPC promoter variant
    Ingrid I L Berk-Planken
    Department of Internal Medicine, Erasmus MC, Erasmus University Rotterdam, The Netherlands
    Diabetes Care 26:427-32. 2003
    ..Therefore, we studied the effect of atorvastatin 10 mg (A10) and 80 mg (A80) on HL activity in 198 patients with type 2 diabetes...
  85. ncbi request reprint Tissue factor pathway inhibitor and other endothelium-dependent hemostatic factors in elderly individuals with normal or impaired glucose tolerance and type 2 diabetes
    Paul B Leurs
    Department of Endocrinology, University Hospital, Maastricht, The Netherlands
    Diabetes Care 25:1340-5. 2002
    ..Endothelial damage precedes atherosclerotic changes of the vascular wall. Therefore, several markers of endothelial dysfunction were examined in elderly subjects with IGT and elderly patients with type 2 diabetes...
  86. ncbi request reprint Thyroid dysfunction during pregnancy and in the first postpartum year in women with diabetes mellitus type 1
    P Robert J Gallas
    Department of Endocrinology and Metabolism, Academic Medical Centre, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    Eur J Endocrinol 147:443-51. 2002
    ..To assess prevalence, incidence and risk factors in The Netherlands we performed a prospective cohort study...
  87. ncbi request reprint Serial echocardiographic assessment of left ventricular mass
    Ronald P Stolk
    J Hypertens 23:460-1; author reply 461-2. 2005