Research Topics
Genomes and GenesSpecies | I E SommerSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
The genetics of symptom dimensions of schizophrenia: review and meta-analysisT Rietkerk
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, B01 206, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
Schizophr Res 102:197-205. 2008..However, the genetic background of symptom dimensions is not clear...
The influence of amphetamine on language activation: an fMRI studyIris E C Sommer
Rudolf Magnus Institute of Neuroscience Psychiatry Department, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
Psychopharmacology (Berl) 183:387-93. 2006..In humans, cerebral dopamine neurotransmission is also correlated to motor dominance. Since language dominance is related to motor dominance, amphetamine might also affect cerebral dominance for language...
Language lateralization in schizophrenia, an fMRI studyI E Sommer
Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
Schizophr Res 52:57-67. 2001..54, p<0.05). We postulate that decreased language lateralization in schizophrenia may result from failure to inhibit the right hemisphere...
Language lateralization in monozygotic twin pairs concordant and discordant for handednessI E C Sommer
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, Neuroscience Division, University Medical Centre Utrecht, The Netherlands
Brain 125:2710-8. 2002..Discordant language dominance may be caused by a relatively late time of splitting of the original embryo, which disrupts the normal development of left-right asymmetry...
Language lateralization in female patients with schizophrenia: an fMRI studyI E C Sommer
Department of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
Schizophr Res 60:183-90. 2003..These findings indicate that lower language lateralization in women is not likely to underlie gender differences in schizophrenia...
Language activation in monozygotic twins discordant for schizophreniaIris E C Sommer
Rudolf Magnus Institute of Neuroscience Psychiatry Department, University Medical Center, Utrecht, The Netherlands
Br J Psychiatry 184:128-35. 2004..In previous functional magnetic resonance imaging (fMRI) studies, participants with schizophrenia showed decreased language lateralisation, resulting from increased activation of the right hemisphere compared with controls...
Do women really have more bilateral language representation than men? A meta-analysis of functional imaging studiesIris E C Sommer
Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Brain 127:1845-52. 2004..It is therefore not likely that differences in language lateralization underlie the general sex differences in cognitive performance, and the neuronal basis for these cognitive sex differences remains elusive...
[Bizarre somatic complaints as a manifestation of schizophrenia]I E C Sommer
Afd Stemmingsstoornissen, Universitair Medisch Centrum Utrecht, divisie Hersenen, B01 206, Heidelberglaan 100, 3584 CX Utrecht
Ned Tijdschr Geneeskd 149:217-20. 2005..The patient's visit to a somatic or general physician is a good opportunity to refer him or her for adequate psychiatric treatment...
Combined analysis of language tasks in fMRI improves assessment of hemispheric dominance for language functions in individual subjectsN F Ramsey
Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, Netherlands
Neuroimage 13:719-33. 2001..Also, the CTA results are very similar to those obtained with conjunction analysis of the same data...
Investigating gene environment interaction in complex diseases: increasing power by selective sampling for environmental exposureM P M Boks
The Rudolf Magnus Institute of Neuroscience, Department of Psychiatry University Medical Centre Utrecht, Utrecht, The Netherlands
Int J Epidemiol 36:1363-9. 2007..However, gene environmental interactions (GEIs) are not easily studied, since high numbers of subjects are required to detect GEI...
Hand-preference and population schizotypy: a meta-analysisM Somers
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, B01 206, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
Schizophr Res 108:25-32. 2009..Bilateral language organisation may underlie loosening of association, possibly leading to higher schizotypy scores...
Reviewing the role of the genes G72 and DAAO in glutamate neurotransmission in schizophreniaM P M Boks
Department of Psychiatry, B01 206, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
Eur Neuropsychopharmacol 17:567-72. 2007..The involvement of this gene is therefore indirect support for the glutamate dysfunction hypothesis in schizophrenia...
A vanishing lesion in the temporal lobe associated with schizophrenialike psychosis and catatoniaKuan H Kho
Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Cogn Behav Neurol 20:232-4. 2007..To present the case of a patient with hallucinations and psychotic symptoms that co-occurs with a temporary lesion in the left posterior temporal lobe...
Deactivation of the parahippocampal gyrus preceding auditory hallucinations in schizophreniaKelly M J Diederen
Department of Psychiatry, Neuroscience Division, University Medical Center, Utrecht, The Netherlands
Am J Psychiatry 167:427-35. 2010..It remains unclear, however, how this activation is triggered. Identifying brain regions that show significant signal changes preceding auditory hallucinations might reveal the origin of these hallucinations...
Schizophrenia risk factors constitute general risk factors for psychiatric symptoms in the populationElemi J Breetvelt
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
Schizophr Res 120:184-90. 2010..However, to our knowledge no large-scale studies have been conducted which examine the specificity of these risk factors in the general population...
Left with the voices or hearing right? Lateralization of auditory verbal hallucinations in schizophreniaIris E C Sommer
J Psychiatry Neurosci 28:217-8; author reply 218-9. 2003
