P E Sijens

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. pmc MRI-determined fat content of human liver, pancreas and kidney
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    World J Gastroenterol 16:1993-8. 2010
  2. ncbi request reprint (1)H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, 9713, GZ Groningen, The Netherlands
    Eur Radiol 16:489-95. 2006
  3. ncbi request reprint Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, The Netherlands
    Eur Radiol 16:898-904. 2006
  4. ncbi request reprint Cerebral 1H MR spectroscopy showing elevation of brain guanidinoacetate in argininosuccinate lyase deficiency
    P E Sijens
    Department of Radiology, University Medical Centre Groningen and University of Groningen, Groningen, 9713 GZ, The Netherlands
    Mol Genet Metab 88:100-2. 2006
  5. ncbi request reprint Cerebral 1H MR spectroscopy revealing white matter NAA decreases in glutaric aciduria type I
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Mol Genet Metab 88:285-9. 2006
  6. ncbi request reprint Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging
    Paul E Sijens
    Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, The Netherlands
    J Hepatol 45:851-5. 2006
  7. ncbi request reprint Diffusion tensor imaging and magnetic resonance spectroscopy of the brain in a patient with Sturge-Weber syndrome
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Acta Radiol 47:972-6. 2006
  8. ncbi request reprint MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Brain Dev 29:317-21. 2007
  9. ncbi request reprint Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cancer Invest 25:706-10. 2007
  10. doi request reprint 1H magnetic resonance spectroscopy in monocarboxylate transporter 8 gene deficiency
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    J Clin Endocrinol Metab 93:1854-9. 2008

Detail Information

Publications58

  1. pmc MRI-determined fat content of human liver, pancreas and kidney
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    World J Gastroenterol 16:1993-8. 2010
    ..To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight...
  2. ncbi request reprint (1)H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, 9713, GZ Groningen, The Netherlands
    Eur Radiol 16:489-95. 2006
    ..In conclusion, the concentrations of Cho, Cr and NAA are reduced in PPMS/SPMS patients, especially in GM and in WML. Despite contrary observations in previous studies, increases in the concentrations of Cr and/or Cho were not observed...
  3. ncbi request reprint Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, The Netherlands
    Eur Radiol 16:898-904. 2006
    ..88; P<0.00001) than in GM (r=-0.69, P<0.01). The demonstrated relationship between DTI parameters and water content in multiple sclerosis patients suggests a potential for therapy monitoring in normal-appearing brain tissue...
  4. ncbi request reprint Cerebral 1H MR spectroscopy showing elevation of brain guanidinoacetate in argininosuccinate lyase deficiency
    P E Sijens
    Department of Radiology, University Medical Centre Groningen and University of Groningen, Groningen, 9713 GZ, The Netherlands
    Mol Genet Metab 88:100-2. 2006
    ....
  5. ncbi request reprint Cerebral 1H MR spectroscopy revealing white matter NAA decreases in glutaric aciduria type I
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Mol Genet Metab 88:285-9. 2006
    ..MR spectroscopy in two patients with glutaric aciduria type I revealed reductions in the white matter N-acetylaspartate signal, in the more severe case accompanied by a loss of glutamate and the appearance of lactate signals...
  6. ncbi request reprint Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging
    Paul E Sijens
    Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, The Netherlands
    J Hepatol 45:851-5. 2006
    ..This pathology has not yet been documented by (1)H MR spectroscopy (MRS) investigation...
  7. ncbi request reprint Diffusion tensor imaging and magnetic resonance spectroscopy of the brain in a patient with Sturge-Weber syndrome
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Acta Radiol 47:972-6. 2006
    ..The N-acetylaspartate decreases and/or choline increases observed here and in eight previously described Sturge-Weber patients probably reflect neuronal loss or dysfunction and demyelination as a result of recurrent seizures...
  8. ncbi request reprint MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Brain Dev 29:317-21. 2007
    ..This observation, combined with the DTI observed ADC increases and FA decrease, indicated a presence of vasogenic edema in the white matter...
  9. ncbi request reprint Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cancer Invest 25:706-10. 2007
    ..001), indicating that these parameters reflect (remaining) axonal structure. Tumor lactate level, also found to decrease under therapy, did not correlate with any other parameter...
  10. doi request reprint 1H magnetic resonance spectroscopy in monocarboxylate transporter 8 gene deficiency
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    J Clin Endocrinol Metab 93:1854-9. 2008
    ..In monocarboxylate transporter 8 (MCT8) gene deficiency, a syndrome combining thyroid and neurological abnormalities, the central nervous system has not yet been characterized by magnetic resonance (MR) spectroscopy...
  11. doi request reprint MR spectroscopy of the brain in Leigh syndrome
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Brain Dev 30:579-83. 2008
    ....
  12. doi request reprint Quantitative multivoxel 1H MR spectroscopy of the brain in children with acute liver failure
    Paul E Sijens
    Department of Radiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur Radiol 18:2601-9. 2008
    ....
  13. doi request reprint Impact of fluoxetine on the human brain in multiple sclerosis as quantified by proton magnetic resonance spectroscopy and diffusion tensor imaging
    Paul E Sijens
    Department of Radiology, University Hospital Groningen, and University of Groningen, The Netherlands
    Psychiatry Res 164:274-82. 2008
    ..These preliminary results provide evidence of a neuroprotective effect of fluoxetine in MS by the observed partial normalization of the structure-related MRS parameter N-acetylaspartate in white matter lesions...
  14. pmc Parametric exploration of the liver by magnetic resonance methods
    Paul E Sijens
    Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Eur Radiol 19:2594-607. 2009
    ....
  15. pmc Liver magnetic resonance imaging: State of the art
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    World J Gastroenterol 16:1558-9. 2010
    ..This topic highlight series thus provides an update of current knowledge in the field of liver MRI...
  16. ncbi request reprint 1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter
    P E Sijens
    Department of Radiology, University Medical Center Groningen, Groningen, The Netherlands
    Eur Radiol 15:1923-6. 2005
    ....
  17. doi request reprint MR spectroscopy and diffusion tensor imaging of the brain in Sjögren-Larsson syndrome
    P E Sijens
    Department of Radiology, University Medical Center Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Mol Genet Metab 98:367-71. 2009
    ..The overall loss of FA in the white matter may reflect a loss of brain tissue water content in SLS patients compared with controls and precede the formation of atrophy...
  18. ncbi request reprint 1H chemical shift imaging of the human brain at age 60-90 years reveals metabolic differences between women and men
    P E Sijens
    Dr Daniel den Hoed Cancer Center, Department of Radiology, University Hospital Rotterdam, The Netherlands
    Magn Reson Med 42:24-31. 1999
    ..These findings are consistent with a sex-related reduction of glucose metabolism in the same brain lobe revealed by positron emission tomography...
  19. ncbi request reprint MR spectroscopy detection of lactate and lipid signals in the brains of healthy elderly people
    P E Sijens
    Department of Radiology, University Hospital Groningen, The Netherlands
    Eur Radiol 11:1495-501. 2001
    ....
  20. ncbi request reprint 1H Magnetic resonance spectroscopy of the internal capsule in human brain: a feasibility study to detect lactate following contralateral motor activity
    Jop P Mostert
    Department of Neurology, University Hospital Groningen, The Netherlands
    Eur Radiol 15:1349-52. 2005
    ....
  21. ncbi request reprint Human brain chemical shift imaging at age 60 to 90: analysis of the causes of the observed sex differences in brain metabolites
    P E Sijens
    Department of Radiology, State University and Academic Hospital Groningen, The Netherlands
    Invest Radiol 36:597-603. 2001
    ....
  22. ncbi request reprint 1H MR spectroscopy monitoring of changes in choline peak area and line shape after Gd-contrast administration
    P E Sijens
    Department of Radiology, Dr Daniel den Hoed Cancer Center, University Hospital Rotterdam, The Netherlands
    Magn Reson Imaging 16:1273-80. 1998
    ..It is concluded that the Gd-induced loss of tumor Cho signal measured after 5 min, typically required for post contrast-MRI and the positioning of the CSI volume on tumor, shows little further change with time, if any...
  23. ncbi request reprint High cerebral guanidinoacetate and variable creatine concentrations in argininosuccinate synthetase and lyase deficiency: implications for treatment?
    F J van Spronsen
    Department of Metabolic Diseases, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Mol Genet Metab 89:274-6. 2006
    ..Because high cerebral guanidinoacetate might be toxic, lowering the arginine supplementation with additional creatine supplementation might be important...
  24. ncbi request reprint Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men
    Paul E Sijens
    Department of Radiology, Univ Hosp Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Radiology 226:889-96. 2003
    ..To assess the effect of aging on the proportions of choline (Cho), creatine, and N-acetylaspartate (NAA) in the brains of elderly women and men...
  25. pmc The added value of quantitative multi-voxel MR spectroscopy in breast magnetic resonance imaging
    M D Dorrius
    Department of Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Eur Radiol 22:915-22. 2012
    ..To determine whether quantitative multivoxel MRS improves the accuracy of MRI in the assessment of breast lesions...
  26. ncbi request reprint Gd-enhanced MR imaging of brain metastases: contrast as a function of dose and lesion size
    P van Dijk
    Department of Radiology, Dr Daniel den Hoed Cancer Center University Hospital Rotterdam, The Netherlands
    Magn Reson Imaging 15:535-41. 1997
    ..It is indicated that the number of detected metastases will increase further at Gd doses beyond 0.3 mmol/kg. Post-Gd MRI contrast increases with lesion size, to an extent that can not be attributed to partial volume attenuation...
  27. doi request reprint Non-invasive liver iron concentration measurement by MRI: comparison of two validated protocols
    Allard W Olthof
    Department of Radiology, Bethesda Hospital, Dr G H Amshoffweg 1, Hoogeveen 7909 AA, The Netherlands
    Eur J Radiol 71:116-21. 2009
    ..In the Kreeftenberg method combining the results of three suboptimal sequences, leads to underestimation of the liver iron concentration...
  28. ncbi request reprint Rapid ELISA assay for plasma D-dimer in the diagnosis of segmental and subsegmental pulmonary embolism. A comparison with pulmonary angiography
    P E Sijens
    Department of Radiology, University Hospital Rotterdam, Daniel den Hoed Cancer Center, The Netherlands
    Thromb Haemost 84:156-9. 2000
    ....
  29. ncbi request reprint Understanding the discrepancies between 31P MR spectroscopy assessed liver metabolite concentrations from different institutions
    P E Sijens
    Department of Radiology, Dr Daniel den Hoed Cancer Center, University Hospital Rotterdam, The Netherlands
    Magn Reson Imaging 16:205-11. 1998
    ..Large reproducible differences were found in liver metabolite peak areas but not in pH, indicating that processing and peak integration methods can only explain part of the discrepancies between the results from different institutions...
  30. doi request reprint Ultrasonography to quantify hepatic fat content: validation by 1H magnetic resonance spectroscopy
    Mireille A Edens
    Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Obesity (Silver Spring) 17:2239-44. 2009
    ..001). This validation study shows that a combination of computer-assessed ultrasound measures from routine ultrasound images can be used to quantitatively assess hepatic fat content...
  31. ncbi request reprint Correlation of proton MR spectroscopy and diffusion tensor imaging
    Roy Irwan
    Department of Radiology, University Medical Center Groningen, 9700 RB Groningen, The Netherlands
    Magn Reson Imaging 23:851-8. 2005
    ..70, P<.00001; correlation across four subjects, 144 data pairs). This is the first association of neuron metabolite contents in volunteers with structure as indicated by DTI...
  32. doi request reprint Long-term reproducibility of phantom signal intensities in nonuniformity corrected STIR-MRI examinations of skeletal muscle
    Alain R Viddeleer
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    MAGMA 22:201-9. 2009
    ..In this study long-term reproducibility of STIR image intensity was assessed under clinical conditions and the required image intensity nonuniformity correction was improved by using phantom scans obtained at multiple positions...
  33. doi request reprint Quantitative multivoxel proton spectroscopy of the brain in developmental delay
    Krijn T Verbruggen
    Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
    J Magn Reson Imaging 30:716-21. 2009
    ..To assess whether proton MR spectroscopy of the brain in children with developmental delay reveals a consistent pattern of abnormalities...
  34. ncbi request reprint Correlation between serum ferritin levels and liver iron concentration determined by MR imaging: impact of hematologic disease and inflammation
    Allard W Olthof
    Department of Radiology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands
    Magn Reson Imaging 25:228-31. 2007
    ..79; n=13; P=.001). It is concluded that in patients without inflammation and in patients with hematologic disease, the content of ferritin in blood is a better predictor of liver iron content than in other patient categories...
  35. doi request reprint Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic evaluation of developmental delay
    Krijn T Verbruggen
    Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Paediatr Neurol 13:181-90. 2009
    ....
  36. ncbi request reprint Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging
    Roy Irwan
    Radiology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Eur Radiol 18:806-13. 2008
    ..001). Even after correction of the algorithm, the problem remaining with the Dixon-based MRI method for the assessment of liver fat content,is that, at the lower end range, liver fat content is systematically overestimated by 4%...
  37. ncbi request reprint 1H magnetic resonance spectroscopy in preclinical Huntington disease
    Joost C H van Oostrom
    Department of Neurology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Brain Res 1168:67-71. 2007
    ..Since other brain imaging methods have shown changes in these study subjects, MRS is not a very sensitive detector of early HD brain pathology...
  38. ncbi request reprint 1H MR chemical shift imaging detection of phenylalanine in patients suffering from phenylketonuria (PKU)
    Paul E Sijens
    Department of Radiology, University Hospital Groningen, Hanzeplein 1, P O Box 30001, Groningen, The Netherlands
    Eur Radiol 14:1895-900. 2004
    ..Best results were obtained at TE=135 ms, relating to the fact that at that particular TE, the visibility of a compound with a T2 of 215 ms still is good, while interfering signals from short-TE compounds are negligible...
  39. ncbi request reprint Fast 3D coronary artery contrast-enhanced magnetic resonance angiography with magnetization transfer contrast, fat suppression and parallel imaging as applied on an anthropomorphic moving heart phantom
    Roy Irwan
    University Medical Center Groningen, State University Groningen, Department of Radiology, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Magn Reson Imaging 24:895-902. 2006
    ..Another advantage of parallel imaging for visualizing the coronary arteries is that the entire heart can be imaged within a few breath-holds...
  40. ncbi request reprint Plantar lipomatosis, unusual facies, and developmental delay: confirmation of Pierpont syndrome
    Gretel G Oudesluijs
    Department of Clinical Genetics, University Medical Center Groningen, The Netherlands
    Am J Med Genet A 137:77-80. 2005
    ..The cause of the entity remains uncertain, the most likely etiologies being X-linked recessive or autosomal dominant genes...
  41. ncbi request reprint Global developmental delay in guanidionacetate methyltransferase deficiency: differences in formal testing and clinical observation
    Krijn T Verbruggen
    University Medical Center Groningen, Beatrix Children s Hospital, University of Groningen, Groningen, The Netherlands
    Eur J Pediatr 166:921-5. 2007
    ....
  42. ncbi request reprint Successful treatment of a guanidinoacetate methyltransferase deficient patient: findings with relevance to treatment strategy and pathophysiology
    Krijn T Verbruggen
    Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, The Netherlands
    Mol Genet Metab 91:294-6. 2007
    ..Addition of high dose ornithine to the treatment led to further normalization of plasma GAA, while cerebral Cr and GAA did not improve further...
  43. ncbi request reprint Fluoxetine increases cerebral white matter NAA/Cr ratio in patients with multiple sclerosis
    Jop P Mostert
    Department of Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands
    Neurosci Lett 402:22-4. 2006
    ..84 at the end of the second week (p=0.007). These findings show evidence for a reversible axonal dysfunction in patients with MS and provide a rationale for investigating whether fluoxetine has neuroprotective effects in MS...
  44. ncbi request reprint Parallel imaging for first-pass myocardial perfusion
    Roy Irwan
    Department of Radiology, University Medical Center Groningen, State University Groningen, 9700 RB Groningen, The Netherlands
    Magn Reson Imaging 25:678-83. 2007
    ..Compared to TSENSE, GRAPPA produced significantly better CNR on the first bolus. More consistent SNR and CNR were obtained from TSENSE images than from GRAPPA images, indicating that the diagnostic value of TSENSE may be better...
  45. ncbi request reprint Phosphorus-31 chemical shift imaging of metastatic tumors located in the spine region
    P E Sijens
    Department of Radiology, Dr Daniel den Hoed Cancer Center, University Hospital Rotterdam, The Netherlands
    Invest Radiol 32:344-50. 1997
    ..Phosphorus-31 magnetic resonance spectroscopy was used in 14 cases to examine metastases of known malignant tumors located in the spine region. The purpose was to test the hypothesis that tumor phosphomonoester (PME) is elevated...
  46. ncbi request reprint Visual stimulation, 1H MR spectroscopy and fMRI of the human visual pathways
    Christine C Boucard
    Laboratory for Experimental Ophthalmology, University of Groningen, Postbus 30001, Groningen, 9700 RB, The Netherlands
    Eur Radiol 15:47-52. 2005
    ..Previous claims about changes in lactate levels in the visual cortex upon visual stimulation may have been based on such erroneous observations...
  47. ncbi request reprint 1H chemical shift imaging characterization of human brain tumor and edema
    Paul E Sijens
    Department of Radiology, University Hospital Groningen, Hanzeplein 1, P O Box 30001, 9700 RB Groningen, The Netherlands
    Eur Radiol 12:2056-61. 2002
    ..The short T2 of choline in tumor and edema implies that short-echo-time 1H chemical shift imaging is most suited in the use of choline elevation as tumor marker...
  48. ncbi request reprint Analysis of the human brain in primary progressive multiple sclerosis with mapping of the spatial distributions using 1H MR spectroscopy and diffusion tensor imaging
    Paul E Sijens
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands
    Eur Radiol 15:1686-93. 2005
    ..This is of interest in view of previous reports in which Cho increases were associated with demyelination and the subsequent breakdown of neurons...
  49. doi request reprint Quantitative multivoxel proton chemical shift imaging of the breast
    Paul E Sijens
    Radiology, University Medical Center Groningen and University of Groningen, The Netherlands
    Magn Reson Imaging 28:314-9. 2010
    ..This opens excellent perspectives to quantitative diagnostic and follow-up studies of focal pathology such as lesions suspected of breast cancer...
  50. ncbi request reprint Exclusion of pulmonary embolism using quantitative plasma D-dimer assays
    P E Sijens
    Department of Radiology, University Hospital Groningen, The Netherlands
    Clin Lab 47:321-6. 2001
    ..In diagnostic algorithms D-dimer can reliably exclude acute segmental and/or massive PE. Further work-up within 48 hours is still necessary in negative D-dimer outcomes to exclude subsegmental PE...
  51. doi request reprint Assessment of image quality of 64-row Dual Source versus Single Source CT coronary angiography on heart rate: a phantom study
    R Dikkers
    Department of Radiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The Netherlands
    Eur J Radiol 70:61-8. 2009
    ..To assess the influence of temporal resolution on image quality of computed tomographic (CT) coronary angiography by comparing 64-row Dual Source CT (DSCT) and Single Source CT (SSCT) at different heart rates...
  52. doi request reprint MR intensity measurements of nondenervated muscle in patients following severe forearm trauma
    A R Viddeleer
    Department of Radiology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    NMR Biomed 24:895-901. 2011
    ..After 6 months, the ipsilateral side can be used for muscle signal intensity comparisons...
  53. ncbi request reprint Phosphorus MR spectroscopy in the treatment of human extremity sarcomas
    P E Sijens
    Department of Radiology, Dr Daniel den Hoed Cancer Center, University Hospital Rotterdam, The Netherlands
    NMR Biomed 11:341-53. 1998
    ..Larger clinical studies are needed to confirm whether correlations of, for instance, pretreatment tumor pH with necrosis at resection and Pi decrease with tumor regression, can be used as a predictive test for clinical response...
  54. doi request reprint The negative predictive value of breast Magnetic Resonance Imaging in noncalcified BIRADS 3 lesions
    M D Dorrius
    Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Radiol 81:209-13. 2012
    ..The purpose of this study is to determine whether breast MRI can provide a sufficient NPV to safely rule out malignancy in mammographic BIRADS 3 lesions...
  55. ncbi request reprint Adenosine triphosphate infusion increases liver energy status in advanced lung cancer patients: an in vivo 31P magnetic resonance spectroscopy study
    Susanne Leij-Halfwerk
    Institute of Internal Medicine II, Erasmus University Medical Center Rotterdam, The Netherlands
    Hepatology 35:421-4. 2002
    ..These changes may contribute to the previously reported beneficial effects of ATP infusion on the nutritional status of lung cancer patients...
  56. doi request reprint Letter to the editor re: Richard J. Maddock et al. "Brain lactate responses during visual stimulation in fasting and hyperglycemic subjects: a proton magnetic resonance study at 1.5 T" [Psychiatry Research 2006; 148:47-54]
    Paul E Sijens
    Psychiatry Res 162:173-4; author reply 175-9. 2008
  57. ncbi request reprint 1H chemical shift imaging, MRI, and diffusion-weighted imaging in vanishing white matter disease
    Paul E Sijens
    Eur Radiol 15:2377-9. 2005
  58. doi request reprint Inverse association between liver fat content and hepatic glucose uptake in patients with type 2 diabetes mellitus
    Ronald Borra
    Medical Imaging Centre of Southwest Finland, Turku University Hospital, FIN 20521 Turku, Finland
    Metabolism 57:1445-51. 2008
    ..This suggests that the beneficial effects of rosiglitazone on liver metabolism are indirect and can be partly explained by increased suppression of nonesterified fatty acid levels, leading to reduced liver fat...