Research Topics
| Peter R SeevinckSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
| Collaborators
|
Detail Information
Publications
Highly localized positive contrast of small paramagnetic objects using 3D center-out radial sampling with off-resonance receptionPeter R Seevinck
Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Magn Reson Med 65:146-56. 2011..In all cases, center-out RAdial Sampling with Off-Resonance reception was shown to generate high positive contrast exactly at the location of the paramagnetic object, as was confirmed by X-ray computed tomography...
Magnetic resonance imaging-based radiation-absorbed dose estimation of 166Ho microspheres in liver radioembolizationPeter R Seevinck
Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Int J Radiat Oncol Biol Phys 83:e437-44. 2012....
FID sampling superior to spin-echo sampling for T2*-based quantification of holmium-loaded microspheres: theory and experimentPeter R Seevinck
Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, The Netherlands
Magn Reson Med 60:1466-76. 2008..HoMS were shown to satisfy the static dephasing regime when investigated with MGEFID and to violate the static dephasing conditions for MGESE at longer echo times typically used in SE...
Magnetic resonance imaging of brain angiogenesis after strokePeter R Seevinck
Biomedical MR Imaging and Spectroscopy Group, Image Sciences Institute, University Medical Center Utrecht, Yalelaan 2, 3584 CM, Utrecht, The Netherlands
Angiogenesis 13:101-11. 2010..Finally, we discuss some pitfalls and limitations that may critically affect the accuracy and interpretation of MRI-based measures of (neo)vascularization after stroke...
Quantification of holmium-166 loaded microspheres: estimating high local concentrations using a conventional multiple gradient echo sequence with S₀-fittingGerrit H van de Maat
Image Sciences Institute, University Medical Center Utrecht, The Netherlands
J Magn Reson Imaging 35:1453-61. 2012....
MRI-based biodistribution assessment of holmium-166 poly(L-lactic acid) microspheres after radioembolisationGerrit H van de Maat
Image Sciences Institute, University Medical Center Utrecht, Q S 459, PO Box 85500, 3508 GA Utrecht, The Netherlands
Eur Radiol 23:827-35. 2013..To demonstrate the feasibility of MRI-based assessment of the intrahepatic Ho-PLLA-MS biodistribution after radioembolisation in order to estimate the absorbed radiation dose...
Factors affecting the sensitivity and detection limits of MRI, CT, and SPECT for multimodal diagnostic and therapeutic agentsPeter R Seevinck
Image Sciences Institute, Dept of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
Anticancer Agents Med Chem 7:317-34. 2007..In this, emphasis was put on the factors that must be taken into account when extrapolating the findings for HoMS to other diagnostic tasks, other contrast agents, other experimental conditions, and other scan protocols...
Holmium nanoparticles: preparation and in vitro characterization of a new device for radioablation of solid malignanciesWouter Bult
Department of Radiology and Nuclear Medicine, Imaging Division, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Pharm Res 27:2205-12. 2010..The present study introduces the preparation and in vitro characterization of a nanoparticle device comprising holmium acetylacetonate for radioablation of unresectable solid malignancies...
Microbrachytherapy using holmium-166 acetylacetonate microspheres: a pilot study in a spontaneous cancer animal modelWouter Bult
Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
Brachytherapy 12:171-7. 2013..This article presents a pilot study in housecats with unresectable liver cancer. Feasibility and tolerability of intratumoral administrations of (166)Ho-AcAc-MS was investigated...
Alginate-lanthanide microspheres for MRI-guided embolotherapyChris Oerlemans
Department of Radiology and Nuclear Medicine, University Medical Center, Utrecht, The Netherlands
Acta Biomater 9:4681-7. 2013..Therefore, the different alginate-lanthanide microsphere formulations developed in this study show great potential for utilization as image-guided embolotherapy agents...
Intratumoral administration of holmium-166 acetylacetonate microspheres: antitumor efficacy and feasibility of multimodality imaging in renal cancerWouter Bult
Imaging Division, Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
PLoS ONE 8:e52178. 2013..This new technique locally ablates renal tumors through high-energy beta particles, while the gamma rays allow for nuclear imaging and the paramagnetism of holmium allows for MRI...
Selective depiction of susceptibility transitions using Laplace-filtered phase mapsChris J G Bakker
Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
Magn Reson Imaging 30:601-9. 2012..Finally, the potential of the Laplace derivative analysis is illustrated by simulations with a Shepp-Logan digital brain phantom and experiments with a gel phantom containing positive and negative focal susceptibility deviations...
On the utility of spectroscopic imaging as a tool for generating geometrically accurate MR images and parameter maps in the presence of field inhomogeneities and chemical shift effectsChris J G Bakker
Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
Magn Reson Imaging 31:86-95. 2013..This perspective is backed up by a demonstration of the significant scan time reduction that may be achieved by the use of compressed sensing for a simple phantom...
