Maroeska M Rovers

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. doi request reprint Empirical comparison of subgroup effects in conventional and individual patient data meta-analyses
    Laura Koopman
    University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Technol Assess Health Care 24:358-61. 2008
  2. ncbi request reprint Persistence of upper respiratory tract infections in a cohort followed from childhood to adulthood
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Fam Pract 23:286-90. 2006
  3. ncbi request reprint Antibiotics for acute otitis media: a meta-analysis with individual patient data
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Lancet 368:1429-35. 2006
  4. doi request reprint The burden of otitis media
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Vaccine 26:G2-4. 2008
  5. doi request reprint Is pacifier use a risk factor for acute otitis media? A dynamic cohort study
    Maroeska M Rovers
    Julius Center for Health Science and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Fam Pract 25:233-6. 2008
  6. ncbi request reprint Risk factors for otitis media: an international perspective
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 139, P O Box 85060, 3508 AB Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 70:1251-6. 2006
  7. doi request reprint Translating research evidence into action in daily practice
    Maroeska M Rovers
    Julius Centrum for Health Sciences and Primary Care, Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 142:29-30. 2010
  8. doi request reprint Influence of single-trial results on clinical practice: example of adenotonsillectomy in children
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 135:970-5. 2009
  9. ncbi request reprint Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient data
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Pediatrics 119:579-85. 2007
  10. doi request reprint Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient data
    Laura Koopman
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 134:128-32. 2008

Detail Information

Publications91

  1. doi request reprint Empirical comparison of subgroup effects in conventional and individual patient data meta-analyses
    Laura Koopman
    University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Technol Assess Health Care 24:358-61. 2008
    ..Our objective is to compare such subgroup effects using the data of six trials (n = 1,643) on the effectiveness of antibiotics in children with acute otitis media (AOM)...
  2. ncbi request reprint Persistence of upper respiratory tract infections in a cohort followed from childhood to adulthood
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Fam Pract 23:286-90. 2006
    ....
  3. ncbi request reprint Antibiotics for acute otitis media: a meta-analysis with individual patient data
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Lancet 368:1429-35. 2006
    ..We aimed to identify subgroups of children who would and would not benefit more than others from treatment with antibiotics...
  4. doi request reprint The burden of otitis media
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Vaccine 26:G2-4. 2008
    ..Conclusive evidence is, however, lacking. More insight into the individual risk factors is required in order to answer the question of why some children recover from OM spontaneously while others need specific intervention...
  5. doi request reprint Is pacifier use a risk factor for acute otitis media? A dynamic cohort study
    Maroeska M Rovers
    Julius Center for Health Science and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Fam Pract 25:233-6. 2008
    ..Recently, the use of a pacifier has been identified as a risk factor for acute otitis media (AOM). The studies performed so far, however, suffer from methodological limitations...
  6. ncbi request reprint Risk factors for otitis media: an international perspective
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 139, P O Box 85060, 3508 AB Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 70:1251-6. 2006
    ..It is not known how this is to be explained, whether by cultural differences or by other factors, such as variation in environmental risk factors for OM...
  7. doi request reprint Translating research evidence into action in daily practice
    Maroeska M Rovers
    Julius Centrum for Health Sciences and Primary Care, Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 142:29-30. 2010
    ..These efforts may also prove to be very helpful to identify evidence gaps and provide recommendations for research priorities in otolaryngology...
  8. doi request reprint Influence of single-trial results on clinical practice: example of adenotonsillectomy in children
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 135:970-5. 2009
    ....
  9. ncbi request reprint Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient data
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Pediatrics 119:579-85. 2007
    ..The goal was to determine the predictors of a prolonged course for children with acute otitis media...
  10. doi request reprint Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient data
    Laura Koopman
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 134:128-32. 2008
    ..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children...
  11. ncbi request reprint Alterations of the oropharyngeal microbial flora after adenotonsillectomy in children: a randomized controlled trial
    Thuy My Le
    Julius Center for Health Sciences and Primary Care, Department of Otorhinolaryngology, E 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, PO Box 85090, 3590 AB Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 133:969-72. 2007
    ....
  12. ncbi request reprint Long-term prognosis of acute otitis media in infancy: determinants of recurrent acute otitis media and persistent middle ear effusion
    Roger A M J Damoiseaux
    Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Fam Pract 23:40-5. 2006
    ..The objective of this study was to assess whether known determinants for recurrent acute otitis media and persistent middle ear effusion after an episode of acute otitis media during childhood also apply to children under 2 years...
  13. pmc Systemic corticosteroid monotherapy for clinically diagnosed acute rhinosinusitis: a randomized controlled trial
    Roderick P Venekamp
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    CMAJ 184:E751-7. 2012
    ..We conducted a randomized controlled trial to examine the effectiveness of systemic corticosteroid monotherapy for clinically diagnosed, uncomplicated acute rhinosinusitis...
  14. ncbi request reprint Effect of adenotonsillectomy on middle ear status in children
    Karin P Q Oomen
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
    Laryngoscope 115:731-4. 2005
    ..To determine the effects of adenotonsillectomy as compared with watchful waiting on the middle ear status of children...
  15. doi request reprint Respiratory syncytial virus and recurrent wheeze in healthy preterm infants
    Maarten O Blanken
    Division of Pediatric Immunology and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
    N Engl J Med 368:1791-9. 2013
    ..The monoclonal antibody palivizumab has shown efficacy in preventing severe RSV infection in high-risk infants...
  16. doi request reprint Immediate adenoidectomy vs initial watchful waiting strategy in children with recurrent upper respiratory tract infections: an economic evaluation
    Chantal W B Boonacker
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    JAMA Otolaryngol Head Neck Surg 139:129-33. 2013
    ..To compare the costs associated with 2 clinical strategies in children with recurrent upper respiratory tract infections (URTIs): immediate adenoidectomy vs an initial watchful waiting strategy...
  17. doi request reprint Treatment of acute rhinosinusitis: discrepancy between guideline recommendations and clinical practice
    Roderick P Venekamp
    Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Fam Pract 29:706-12. 2012
    ..A revised primary care guideline on acute rhinosinusitis (ARS) has been introduced in the Netherlands in 2005, which advocates a more judicious use of antibiotics...
  18. ncbi request reprint Predictors of chronic suppurative otitis media in children
    Erwin L van der Veen
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 132:1115-8. 2006
    ..To determine which factors predict development of chronic suppurative otitis media (CSOM) in children...
  19. doi request reprint Trimethoprim-sulfamethoxazole in children with chronic otitis media: a randomized comparison of costs and effects
    Chantal W B Boonacker
    Julius Center for Health Sciences and Primary Care, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
    Otol Neurotol 29:961-4. 2008
    ..To study the cost-effectiveness of a 6- to 12-week course of high-dose oral trimethoprim-sulfamethoxazole in children with chronic active otitis media (COM)...
  20. ncbi request reprint Differences in mortality on the basis of complete blood count in an unselected population at the emergency department
    Karen Vroonhof
    Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Lab Hematol 12:134-8. 2006
    ..7 g/dL, p < .01), for men no difference was observed. In conclusion, our study shows clinically relevant differences in mortality in hematological parameters in an unselected population at the ED, irrespective of underlying pathology...
  21. doi request reprint Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies
    Wilhelmina G Melsen
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet Infect Dis 13:665-71. 2013
    ..We estimated the attributable mortality using the individual original patient data of published randomised trials of ventilator-associated pneumonia prevention...
  22. doi request reprint IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis
    Marieke J J Ermers
    Department of Paediatric Infectious Diseases, University Medical Centre Utrecht, 3508 AB Utrecht, The Netherlands
    Pediatr Res 70:518-23. 2011
    ....
  23. doi request reprint Intranasal corticosteroid monotherapy in acute rhinosinusitis: an evidence-based case report
    Roderick P Venekamp
    Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 142:783-8. 2010
    ....
  24. ncbi request reprint Prediction of asthma in young adults using childhood characteristics: Development of a prediction rule
    Walter A F Balemans
    Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre Utrecht, KH 01 419 0, PO Box 85090, Lundlaan 6, 3508 AB Utrecht, The Netherlands
    J Clin Epidemiol 59:1207-12. 2006
    ..To develop an easily applicable prediction rule for asthma in young adulthood using childhood characteristics...
  25. ncbi request reprint Otitis media
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre, PO Box 85060, 3508 AB, Utrecht, Netherlands
    Lancet 363:465-73. 2004
    ..The ideal intervention for OM, however, does not yet exist, and an urgent need remains to explore new and creative options based on modern insights into the pathophysiology of OM...
  26. doi request reprint Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children
    Erwin L van der Veen
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
    J Antimicrob Chemother 63:1011-6. 2009
    ..The aim of this study was to test the hypothesis that trimethoprim/sulfamethoxazole selects for integron-positive and multidrug-resistant Enterobacteriaceae in the intestinal flora...
  27. doi request reprint Antibiotics for acute otitis media in children
    Roderick P Venekamp
    Department of Otorhinolaryngology and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
    Cochrane Database Syst Rev 1:CD000219. 2013
    ..Acute otitis media (AOM) is one of the most common diseases in early infancy and childhood. Antibiotic use for AOM varies from 56% in the Netherlands to 95% in the USA, Canada and Australia...
  28. ncbi request reprint Trends in doctor consultations, antibiotic prescription, and specialist referrals for otitis media in children: 1995-2003
    Astrid I O Plasschaert
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Pediatrics 117:1879-86. 2006
    ..Reported trends regarding the incidence of otitis media and antibiotic prescription rates are inconsistent...
  29. ncbi request reprint International perspectives on management of acute otitis media: a qualitative review
    Anne G M Schilder
    Department of Otorhinolaryngology KE 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, P O Box 85090, 3508 AB, Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 68:29-36. 2004
    ..With antibiotic resistance rising and more evidence regarding the limited clinical efficacy of antibiotics becoming available, interest in managing AOM other than with antibiotics is renewed...
  30. pmc Recurrence up to 3.5 years after antibiotic treatment of acute otitis media in very young Dutch children: survey of trial participants
    Natália Bezáková
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
    BMJ 338:b2525. 2009
    ..To determine the long term effects of antibiotic treatment for acute otitis media in young children...
  31. ncbi request reprint Is asthma in 2-12 year-old children associated with physician-attended recurrent upper respiratory tract infections?
    Eelko Hak
    Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
    Eur J Epidemiol 18:899-902. 2003
    ..5, 95% confidence interval: 1.1-6.1). As a consequence, antibiotic prescriptions and referrals to hospitals occurred more frequently among asthmatics than controls...
  32. doi request reprint Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis media
    Laura Koopman
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Epidemiol 167:540-5. 2008
    ..In the authors' empirical example, imputation within trials appears to be the most appropriate approach of handling missing data in individual patient data meta-analyses...
  33. ncbi request reprint Mannose-binding lectin and upper respiratory tract infections in children and adolescents: a review
    Jopje M Ruskamp
    Department of Pediatric Immunology, Wilhelmina Children s Hospital, University Medical Center, Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 132:482-6. 2006
    ..To review the literature on mannose-binding lectin (MBL) polymorphisms and susceptibility for upper respiratory tract infection (URI) in children and adolescents...
  34. pmc Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trial
    Birgit K van Staaij
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
    BMJ 329:651. 2004
    ..To assess the effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy...
  35. doi request reprint A trial of treatment for acute otorrhea in children with tympanostomy tubes
    Thijs M A Van Dongen
    From the Department of Epidemiology, Julius Center for Health Sciences and Primary Care T M A D, G J M G H, R P V, M M R, A G M S, and the Department of Otorhinolaryngology, Division of Surgical Specialties G J M G H, R P V, A G M S, University Medical Center Utrecht, Utrecht, the Department of Social Dentistry, Academic Center for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam G J M G H, and the Departments of Operating Rooms and Health Evidence, Radboud University Medical Center, Nijmegen M M R all in the Netherlands and the Ear Institute, University College London, London A G M S
    N Engl J Med 370:723-33. 2014
    ..Recent guidance for the management of acute otorrhea in children with tympanostomy tubes is based on limited evidence from trials comparing oral antibiotic agents with topical antibiotics...
  36. pmc Prospective validation of a prognostic model for respiratory syncytial virus bronchiolitis in late preterm infants: a multicenter birth cohort study
    Maarten O Blanken
    Department Pediatric Immunology and Infectious Diseases, University Medical Center, Utrecht, Utrecht, The Netherlands
    PLoS ONE 8:e59161. 2013
    ..This study aimed to update and validate a prediction rule for respiratory syncytial virus (RSV) hospitalization in preterm infants 33-35 weeks gestational age (WGA)...
  37. doi request reprint A nonrandomized comparison of stapes surgery with and without a vein graft in patients with otosclerosis
    Arnold J N Bittermann
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Utrecht, The Netherlands
    Otol Neurotol 34:827-31. 2013
    ..To evaluate the effectiveness of primary stapes surgery with and without a vein graft in patients with otosclerosis and to determine the differences in the postoperative gain in air-bone gap (ABG) and air-conduction (AC)...
  38. doi request reprint High concentrations of amniotic fluid proinflammatory cytokines in healthy neonates are associated with low risk of respiratory syncytial virus bronchiolitis
    Michiel L Houben
    Department of Pediatrics, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Pediatr Infect Dis J 31:931-4. 2012
    ..Mechanisms underlying RSV bronchiolitis in healthy term infants are largely unknown. Sterile intraamniotic inflammation and chorioamnionitis have been associated with increased lung volume and compliance...
  39. doi request reprint Is a positive family history predictive for recurrent acute otitis media in children? An evidence-based case report
    Monique Albersen
    Julius Centre for Health Sciences and Primary Care, Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 142:31-5. 2010
    ..Family history increases the absolute risk, but not in a way that it will help to predict rAOM accurately...
  40. doi request reprint Atopic disease and exhaled nitric oxide in an unselected population of young adults
    Charlotte J J van Asch
    Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre, Utrecht, The Netherlands
    Ann Allergy Asthma Immunol 100:59-65. 2008
    ..However, the independent influence of different atopic entities (eczema, allergic rhinitis, and asthma) on FeNO has never been studied in the general population...
  41. doi request reprint Alterations in the nasopharyngeal bacterial flora after adenoidectomy in children: a systematic review
    Johanna W M Aarts
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 142:15-20.e1. 2010
    ..To review the current literature on alterations in the nasopharyngeal bacterial flora in relation to adenoidectomy in children with recurrent upper respiratory tract infections (rURTIs)...
  42. doi request reprint Cost effectiveness of pneumococcal conjugate vaccination against acute otitis media in children: a review
    Chantal W B Boonacker
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Pharmacoeconomics 29:199-211. 2011
    ..Uniform methods for estimating direct and indirect costs of AOM should be agreed upon to reliably compare the cost effectiveness of available and future pneumococcal vaccines against AOM...
  43. doi request reprint Differences in interaction and subgroup-specific effects were observed between randomized and nonrandomized studies in three empirical examples
    Amand F Schmidt
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Clin Epidemiol 66:599-607. 2013
    ..To determine the comparability of subgroup-specific and interaction effects (differences between subgroups) between different study designs...
  44. doi request reprint Awareness of, opinions about, and adherence to evidence-based guidelines in otorhinolaryngology
    Mark C J Aarts
    Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 138:148-52. 2012
    ..Guidelines may assist physicians and patients in decisions about effective and safe care. Little is known about the awareness of, opinions about, and adherence to evidence-based guidelines in otolaryngology...
  45. ncbi request reprint Systemic corticosteroids for acute sinusitis
    Roderick P Venekamp
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, Utrecht, Netherlands, 3508 GA
    Cochrane Database Syst Rev 12:CD008115. 2011
    ..Acute sinusitis is a common reason for patients to seek primary care consultations. The related impairment of daily functioning and quality of life is attributable to symptoms such as facial pain and nasal congestion...
  46. ncbi request reprint Effect of pneumococcal vaccination on otitis media with effusion in children older than 1 year
    Thuy My Le
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Pediatr 166:1049-52. 2007
    ..Therefore, these vaccinations are not indicated in the prevention of OME in these children...
  47. ncbi request reprint Effectiveness of trimethoprim/sulfamethoxazole for children with chronic active otitis media: a randomized, placebo-controlled trial
    Erwin L van der Veen
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, Netherlands
    Pediatrics 119:897-904. 2007
    ..The goal was to determine the clinical effectiveness of prolonged outpatient treatment with trimethoprim/sulfamethoxazole for children with chronic active otitis media...
  48. doi request reprint Polymorphisms in the mannan-binding lectin gene are not associated with questionnaire-reported respiratory tract infections in children
    Jopje M Ruskamp
    Department of Pediatrics, Wilhelmina Children s Hospital, University Medical Center Utrecht, University of Utrecht, Lundlaan 6, Utrecht, The Netherlands
    J Infect Dis 198:1707-13. 2008
    ..Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children...
  49. doi request reprint A systematic review of diagnostic criteria for acute mastoiditis in children
    Maaike T A van den Aardweg
    Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Otol Neurotol 29:751-7. 2008
    ..To review systematically the literature for the current criteria and strategies used to diagnose acute mastoiditis in children...
  50. ncbi request reprint Influence of sampling technique on detection of potential pathogens in the nasopharynx
    Erwin L van der Veen
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 132:752-5. 2006
    ..To determine the optimal approach for nasopharyngeal culture and to establish which approach children tolerate best...
  51. doi request reprint Increased risk of wheeze and decreased lung function after respiratory syncytial virus infection
    Kim Zomer-Kooijker
    Department of Paediatric Pulmonology and Allergology, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 9:e87162. 2014
    ..A relationship between hospitalization for respiratory syncytial virus (RSV) bronchiolitis and asthma development has been suggested in case-control studies...
  52. ncbi request reprint [Oral glucocorticoids for acute rhinosinusitis: an RCT]
    Roderick P Venekamp
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A5808. 2013
    ..To determine the efficacy of a short course of oral glucocorticoids in adult patients with acute rhinosinusitis...
  53. pmc Subgroup effects despite homogeneous heterogeneity test results
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Med Res Methodol 10:43. 2010
    ..Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects...
  54. doi request reprint A small effect of adding antiviral agents in treating patients with severe Bell palsy
    Erwin L van der Veen
    Department of Otorhinolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 146:353-7. 2012
    ....
  55. ncbi request reprint [Effectiveness of adenoidectomy or watchful waiting in children with recurrent upper respiratory tract infections: no differences found in randomised trial]
    Chantal W B Boonacker
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 156:A4380. 2012
    ..To assess the effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections...
  56. doi request reprint The cost-utility of bilateral cochlear implantation: a systematic review
    Marc J W Lammers
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Laryngoscope 121:2604-9. 2011
    ..Given this debate, this study's objective was to review the literature on the cost-utility of bilateral cochlear implantation in both children and adults, and study the impact of the used cost and quality-of-life estimates...
  57. ncbi request reprint Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysis
    Irene P Jongerden
    Department of Medicine, Division of Internal Medicine and Infectious Diseases, Eijkman Winkler Centre for Medical Microbiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
    Crit Care Med 35:260-70. 2007
    ..Yet effectiveness regarding patient safety and costs of these systems has not been carefully analyzed...
  58. ncbi request reprint Chronic suppurative otitis media: a review
    Monique Verhoeff
    Department of Otorhinolaryngology KE04 140 5, Wilhelmina Children s Hospital, University Medical Centre Utrecht, P O Box 85090, 3508 AB Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 70:1-12. 2006
    ..Optimal treatment strategy has not been established yet. The objective of this review is to present and evaluate the current state of knowledge of CSOM...
  59. ncbi request reprint Bayes' theorem: a negative example of a RCT on grommets in children with glue ear
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, The Netherlands
    Eur J Epidemiol 20:23-8. 2005
    ..The results showed that our trial had little or no impact on the beliefs of the ENT-surgeons, i.e. they did not adjust their belief to the extent that was expected according to Bayes' theorem...
  60. doi request reprint Primary stapes surgery in patients with otosclerosis: prediction of postoperative outcome
    Arnold J N Bittermann
    Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center, Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 137:780-4. 2011
    ..To evaluate the audiometric results of primary stapes surgery in patients with otosclerosis and to determine predictors of a postoperative air-bone gap (ABG) of 10 dB or less and a postoperative gain in air conduction (AC) exceeding 20 dB...
  61. doi request reprint A comparison of subgroup analyses in grant applications and publications
    Chantal W B Boonacker
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 174:219-25. 2011
    ..Both nonreporting prespecified subgroup analyses and reporting post-hoc subgroup analyses are common. More guidance is clearly needed...
  62. doi request reprint No evidence for diagnostic value of Mallampati score in patients suspected of having obstructive sleep apnea syndrome
    Sander Bins
    Julius Centre for Health Sciences and Primary Care, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 145:199-203. 2011
    ..To analyze whether the Mallampati score is reliable as a simple diagnostic test for predicting obstructive sleep apnea syndrome (OSAS)...
  63. doi request reprint The value of a mandibular repositioning appliance for the treatment of nonapneic snoring
    Mark C J Aarts
    Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 144:170-3. 2011
    ..No effect on quality of life and daytime sleepiness of partners was found. Furthermore, evidence for sustained long-term effects and complete recovery is lacking...
  64. doi request reprint Salvage laryngectomy after primary radiotherapy: what are prognostic factors for the development of pharyngocutaneous fistulae?
    Mark C J Aarts
    Department of Otorhinolaryngology, University Medical Centre Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 144:5-9. 2011
    ..g. diabetes mellitus, alcohol consumption, smoking, suture materials and surgical technique used...
  65. doi request reprint Interventions in health care professionals to improve treatment in children with upper respiratory tract infections
    Chantal W B Boonacker
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 74:1113-21. 2010
    ..To assess the effectiveness of these interventions, and when more are effective--which works best. And to analyse the costs associated with these interventions...
  66. doi request reprint The diagnostic value of diffusion-weighted magnetic resonance imaging in detecting a residual cholesteatoma
    Mark C J Aarts
    Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 143:12-6. 2010
    ....
  67. doi request reprint Remarkable differences between three evidence-based guidelines on management of obstructive sleep apnea-hypopnea syndrome
    Mark C J Aarts
    Department of Otorhinolaryngology, University Medical Centre, Utrecht, The Netherlands
    Laryngoscope 123:283-91. 2013
    ....
  68. pmc Estimating measures of interaction on an additive scale for preventive exposures
    Mirjam J Knol
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, GA, Utrecht, The Netherlands
    Eur J Epidemiol 26:433-8. 2011
    ..23; 0.49], AP = -0.29 [95%CI: -0.98; 0.40], S = 0.43 [95%CI: 0.07; 2.60]), all indicating negative interaction. Preventive factors should not be used to calculate measures of interaction on an additive scale without recoding...
  69. doi request reprint No evidence for the diagnostic value of Borrelia serology in patients with sudden hearing loss
    Renée Bakker
    Department of Otolaryngology, University Medical Centre, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 146:539-43. 2012
    ..Neuroborreliosis seems to be a rare cause of sudden SHL, and routine screening of patients for borrelia antibodies in serum should therefore not be recommended...
  70. pmc The effect of high dose inhaled corticosteroids on wheeze in infants after respiratory syncytial virus infection: randomised double blind placebo controlled trial
    Marieke J J Ermers
    Department of Paediatric Infectious Diseases, Wilhelmina Children s Hospital, University Medical Centre Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands
    BMJ 338:b897. 2009
    ....
  71. doi request reprint Estimating the attributable mortality of ventilator-associated pneumonia from randomized prevention studies
    Wilhelmina G Melsen
    Julius Center for Health Sciences and Primary Care, the Department of Emergency Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
    Crit Care Med 39:2736-42. 2011
    ..To assess the attributable mortality of ventilator-associated pneumonia using results from randomized controlled trials on ventilator-associated pneumonia prevention...
  72. doi request reprint Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: a systematic review
    Digna M Kamalski
    Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Otolaryngol Head Neck Surg 143:181-5. 2010
    ..To identify all disease-specific health-related quality-of-life (HR-QoL) instruments used to assess tinnitus in clinical trials and detail their psychometric properties...
  73. ncbi request reprint Ventilator-associated pneumonia and mortality: a systematic review of observational studies
    Wilhelmina G Melsen
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Crit Care Med 37:2709-18. 2009
    ..Ventilator-associated pneumonia is generally believed to increase the mortality of patients. This notion is predominantly based on the results of observational studies...
  74. pmc Penicillin for acute sore throat in children: randomised, double blind trial
    Sjoerd Zwart
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, Netherlands
    BMJ 327:1324. 2003
    ..To assess the effectiveness of penicillin for three days and treatment for seven days compared with placebo in resolving symptoms in children with sore throat...
  75. ncbi request reprint A systematic review of analytical methods used to study subgroups in (individual patient data) meta-analyses
    Laura Koopman
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Clin Epidemiol 60:1002-9. 2007
    ..To determine whether individual patient data meta-analyses (IPDMA) are used to perform subgroup analyses and to study whether the analytical methods regarding subgroup analyses differ between IPDMA and conventional meta-analyses (CMA)...
  76. pmc The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional study
    Michiel L Houben
    Department of Pediatrics, Wilhelmina Children s Hospital, Utrecht University Medical Center, Utrecht, The Netherlands
    PLoS ONE 4:e6572. 2009
    ..The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor...
  77. ncbi request reprint Differences in mortality on the basis of laboratory parameters in an unselected population at the Emergency Department
    Karen Vroonhof
    Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht, The Netherlands
    Clin Chem Lab Med 43:536-41. 2005
    ..Therefore, glucose and lactate should be routinely added to a blood gas request. Our study shows differences in mortality for laboratory parameters in patients visiting the emergency department, irrespective of the underlying pathology...
  78. doi request reprint alpha-Blockers to assist stone clearance after extracorporeal shock wave lithotripsy: a meta-analysis
    Yefang Zhu
    Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands
    BJU Int 106:256-61. 2010
    ..To review the evidence for the use of alpha-blockers after extracorporeal shock wave lithotripsy (ESWL) in enhancing the effectiveness of renal and ureteric stone clearance...
  79. ncbi request reprint Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in children
    Birgit K van Staaij
    Julius Center for Health Sciences and Primary Care, University Medical Center stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Int J Pediatr Otorhinolaryngol 67:1091-7. 2003
    ..The infrared tympanic membrane thermometer (ITT) seems ideal for measuring central body temperature. Its accuracy, however, is still debated, and the feasibility of daily temperature measurements with an ITT has not been described...
  80. doi request reprint What is the effect of time between sequential cochlear implantations on hearing in adults and children? A systematic review of the literature
    Yvette E Smulders
    Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
    Laryngoscope 121:1942-9. 2011
    ..This review article investigates the effect of time between sequential cochlear implantations on hearing results in both adults and children...
  81. ncbi request reprint Representativeness of trial populations: an example from a trial of adenotonsillectomy in children
    Emma H van den Akker
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital Utrecht, The Netherlands
    Acta Otolaryngol 123:297-301. 2003
    ..To compare demographic and disease-specific characteristics of children included in a trial of the effectiveness of adenotonsillectomy with those of children who, although eligible, were not randomized...
  82. pmc Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
    Carole N M Brouwer
    Department of Paediatrics, Spaarne Hospital, Postbus 770, 2130 AT Hoofddorp, The Netherlands
    Qual Life Res 16:1357-73. 2007
    ..Apart from the generic TAIQOL subscales, both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM...
  83. ncbi request reprint Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trial
    Birgit K van Staaji
    Clin Otolaryngol 30:60-3. 2005
    ..To assess the effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy...
  84. ncbi request reprint Otitis media meta-analysis
    Maroeska M Rovers
    Pediatrics 114:508-9; author reply 508-9. 2004
  85. ncbi request reprint Effect of pneumococcal vaccination on quality of life in children with recurrent acute otitis media: a randomized, controlled trial
    Carole N M Brouwer
    Department of Pediatrics, Spaarne Hospital Haarlem, Haarlem, Netherlands
    Pediatrics 115:273-9. 2005
    ..Pneumococcal vaccination for AOM seems to have only modest clinical efficacy. Thus far, the effects on health-related quality of life (HRQoL) or functional health status (FHS) have not been studied...
  86. ncbi request reprint Recent advances in otitis media. 1. Epidemiology, natural history, and risk factors
    Kathleen A Daly
    Department of Otolaryngology, University of Minnesota, Minneapolis, USA
    Ann Otol Rhinol Laryngol Suppl 194:8-15. 2005
  87. ncbi request reprint Health-related quality of life in children with otitis media
    Carole N M Brouwer
    Department of Paediatrics, Spaarne Hospital Hoofddorp, Postbus 770, 2130 AT Hoofddorp, The Netherlands
    Int J Pediatr Otorhinolaryngol 69:1031-41. 2005
    ....
  88. ncbi request reprint No differences in physical activity in (un)diagnosed asthma and healthy controls
    Rene van Gent
    Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
    Pediatr Pulmonol 42:1018-23. 2007
    ..Childhood asthma does not appear to be associated with a decreased level of daily physical activity in our study population...
  89. ncbi request reprint Long-term effects of pediatric adenotonsillectomy on serum immunoglobulin levels: results of a randomized controlled trial
    Emma H van den Akker
    Department of Otorhinolaryngology, Wilhelmina Children s Hospital University Medical Center Utrecht, The Netherlands
    Ann Allergy Asthma Immunol 97:251-6. 2006
    ....
  90. ncbi request reprint Excessive body weight is associated with additional loss of quality of life in children with asthma
    Rene van Gent
    Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
    J Allergy Clin Immunol 119:591-6. 2007
    ..Asthma and excessive body weight frequently coexist, whereas the exact relationship between the 2 diseases is unknown...
  91. ncbi request reprint Quality of life in children with undiagnosed and diagnosed asthma
    Rene van Gent
    Department of Pediatrics, Maxima Medical Centre, P O Box 7777, 5500 MB Veldhoven, The Netherlands
    Eur J Pediatr 166:843-8. 2007
    ..05), with highest absence rate in those with diagnosed asthma. In conclusion, both undiagnosed and diagnosed asthma have a significant impact on the quality of life of both children and their caregivers...