Research Topics
Species | Maroeska M RoversSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Empirical comparison of subgroup effects in conventional and individual patient data meta-analysesLaura Koopman
University Medical Center Utrecht, Utrecht, The Netherlands
Int J Technol Assess Health Care 24:358-61. 2008..Our objective is to compare such subgroup effects using the data of six trials (n = 1,643) on the effectiveness of antibiotics in children with acute otitis media (AOM)...
Is pacifier use a risk factor for acute otitis media? A dynamic cohort studyMaroeska M Rovers
Julius Center for Health Science and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Fam Pract 25:233-6. 2008..Recently, the use of a pacifier has been identified as a risk factor for acute otitis media (AOM). The studies performed so far, however, suffer from methodological limitations...
Translating research evidence into action in daily practiceMaroeska M Rovers
Julius Centrum for Health Sciences and Primary Care, Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:29-30. 2010..These efforts may also prove to be very helpful to identify evidence gaps and provide recommendations for research priorities in otolaryngology...
Risk factors for otitis media: an international perspectiveMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 139, P O Box 85060, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 70:1251-6. 2006..It is not known how this is to be explained, whether by cultural differences or by other factors, such as variation in environmental risk factors for OM...
Antibiotics for acute otitis media: a meta-analysis with individual patient dataMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
Lancet 368:1429-35. 2006..We aimed to identify subgroups of children who would and would not benefit more than others from treatment with antibiotics...
Persistence of upper respiratory tract infections in a cohort followed from childhood to adulthoodMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
Fam Pract 23:286-90. 2006....
Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient dataMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Pediatrics 119:579-85. 2007..The goal was to determine the predictors of a prolonged course for children with acute otitis media...
Influence of single-trial results on clinical practice: example of adenotonsillectomy in childrenMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 135:970-5. 2009....
The burden of otitis mediaMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Vaccine 26:G2-4. 2008..Conclusive evidence is, however, lacking. More insight into the individual risk factors is required in order to answer the question of why some children recover from OM spontaneously while others need specific intervention...
Alterations of the oropharyngeal microbial flora after adenotonsillectomy in children: a randomized controlled trialThuy My Le
Julius Center for Health Sciences and Primary Care, Department of Otorhinolaryngology, E 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, PO Box 85090, 3590 AB Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 133:969-72. 2007....
Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient dataLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 134:128-32. 2008..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children...
Long-term prognosis of acute otitis media in infancy: determinants of recurrent acute otitis media and persistent middle ear effusionRoger A M J Damoiseaux
Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Fam Pract 23:40-5. 2006..No sufficiently discriminatory prognostic model could be constructed for either outcome measure. CONCLUSION: Prediction of recurrent acute otitis media or persistent middle ear effusion in individual young children remains poor...
Systemic corticosteroid monotherapy for clinically diagnosed acute rhinosinusitis: a randomized controlled trialRoderick P Venekamp
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
CMAJ 184:E751-7. 2012..We conducted a randomized controlled trial to examine the effectiveness of systemic corticosteroid monotherapy for clinically diagnosed, uncomplicated acute rhinosinusitis...
Effect of adenotonsillectomy on middle ear status in childrenKarin P Q Oomen
Department of Otorhinolaryngology, Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands
Laryngoscope 115:731-4. 2005....
Treatment of acute rhinosinusitis: discrepancy between guideline recommendations and clinical practiceRoderick P Venekamp
Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
Fam Pract 29:706-12. 2012..A revised primary care guideline on acute rhinosinusitis (ARS) has been introduced in the Netherlands in 2005, which advocates a more judicious use of antibiotics...
Differences in mortality on the basis of complete blood count in an unselected population at the emergency departmentKaren Vroonhof
Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Lab Hematol 12:134-8. 2006..7 g/dL, p < .01), for men no difference was observed.In conclusion, our study shows clinically relevant differences in mortality in hematological parameters in an unselected population at the ED, irrespective of underlying pathology...
Predictors of chronic suppurative otitis media in childrenErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:1115-8. 2006..To determine which factors predict development of chronic suppurative otitis media (CSOM) in children...
Trimethoprim-sulfamethoxazole in children with chronic otitis media: a randomized comparison of costs and effectsChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
Otol Neurotol 29:961-4. 2008..To study the cost-effectiveness of a 6- to 12-week course of high-dose oral trimethoprim-sulfamethoxazole in children with chronic active otitis media (COM)...
IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitisMarieke J J Ermers
Department of Paediatric Infectious Diseases, University Medical Centre Utrecht, 3508 AB Utrecht, The Netherlands
Pediatr Res 70:518-23. 2011....
Prediction of asthma in young adults using childhood characteristics: Development of a prediction ruleWalter A F Balemans
Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre Utrecht, KH 01 419 0, PO Box 85090, Lundlaan 6, 3508 AB Utrecht, The Netherlands
J Clin Epidemiol 59:1207-12. 2006..To develop an easily applicable prediction rule for asthma in young adulthood using childhood characteristics...
Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in childrenErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
J Antimicrob Chemother 63:1011-6. 2009..The aim of this study was to test the hypothesis that trimethoprim/sulfamethoxazole selects for integron-positive and multidrug-resistant Enterobacteriaceae in the intestinal flora...
Otitis mediaMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre, PO Box 85060, 3508 AB, Utrecht, Netherlands
Lancet 363:465-73. 2004..The ideal intervention for OM, however, does not yet exist, and an urgent need remains to explore new and creative options based on modern insights into the pathophysiology of OM...
Intranasal corticosteroid monotherapy in acute rhinosinusitis: an evidence-based case reportRoderick P Venekamp
Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:783-8. 2010....
Antibiotics for acute otitis media in childrenRoderick P Venekamp
Department of Otorhinolaryngology and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
Cochrane Database Syst Rev 1:CD000219. 2013..Acute otitis media (AOM) is one of the most common diseases in early infancy and childhood. Antibiotic use for AOM varies from 56% in the Netherlands to 95% in the USA, Canada and Australia...
Recurrence up to 3.5 years after antibiotic treatment of acute otitis media in very young Dutch children: survey of trial participantsNatália Bezáková
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 338:b2525. 2009..To determine the long term effects of antibiotic treatment for acute otitis media in young children...
International perspectives on management of acute otitis media: a qualitative reviewAnne G M Schilder
Department of Otorhinolaryngology KE 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, P O Box 85090, 3508 AB, Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 68:29-36. 2004..With antibiotic resistance rising and more evidence regarding the limited clinical efficacy of antibiotics becoming available, interest in managing AOM other than with antibiotics is renewed...
Is asthma in 2-12 year-old children associated with physician-attended recurrent upper respiratory tract infections?Eelko Hak
Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
Eur J Epidemiol 18:899-902. 2003..5, 95% confidence interval: 1.1-6.1). As a consequence, antibiotic prescriptions and referrals to hospitals occurred more frequently among asthmatics than controls...
Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis mediaLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Epidemiol 167:540-5. 2008..In the authors' empirical example, imputation within trials appears to be the most appropriate approach of handling missing data in individual patient data meta-analyses...
Trends in doctor consultations, antibiotic prescription, and specialist referrals for otitis media in children: 1995-2003Astrid I O Plasschaert
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Pediatrics 117:1879-86. 2006..The rising antibiotic prescription rate for otitis media causes concern, because this may induce increasing medical costs and antibiotic resistance...
Mannose-binding lectin and upper respiratory tract infections in children and adolescents: a reviewJopje M Ruskamp
Department of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:482-6. 2006..Large prospective cohort studies with regular documentation of URI and possible confounders such as atopy and environmental factors are required to establish the role of MBL polymorphisms in susceptibility for URI...
Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trialBirgit K van Staaij
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 329:651. 2004..12 children had complications related to surgery. CONCLUSION: Adenotonsillectomy has no major clinical benefits over watchful waiting in children with mild symptoms of throat infections or adenotonsillar hypertrophy...
High concentrations of amniotic fluid proinflammatory cytokines in healthy neonates are associated with low risk of respiratory syncytial virus bronchiolitisMichiel L Houben
Department of Pediatrics, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Pediatr Infect Dis J 31:931-4. 2012..Mechanisms underlying RSV bronchiolitis in healthy term infants are largely unknown. Sterile intraamniotic inflammation and chorioamnionitis have been associated with increased lung volume and compliance...
Atopic disease and exhaled nitric oxide in an unselected population of young adultsCharlotte J J van Asch
Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre, Utrecht, The Netherlands
Ann Allergy Asthma Immunol 100:59-65. 2008..However, the independent influence of different atopic entities (eczema, allergic rhinitis, and asthma) on FeNO has never been studied in the general population...
Alterations in the nasopharyngeal bacterial flora after adenoidectomy in children: a systematic reviewJohanna W M Aarts
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:15-20.e1. 2010..To review the current literature on alterations in the nasopharyngeal bacterial flora in relation to adenoidectomy in children with recurrent upper respiratory tract infections (rURTIs)...
Cost effectiveness of pneumococcal conjugate vaccination against acute otitis media in children: a reviewChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Pharmacoeconomics 29:199-211. 2011..Uniform methods for estimating direct and indirect costs of AOM should be agreed upon to reliably compare the cost effectiveness of available and future pneumococcal vaccines against AOM...
Is a positive family history predictive for recurrent acute otitis media in children? An evidence-based case reportMonique Albersen
Julius Centre for Health Sciences and Primary Care, Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:31-5. 2010..Family history increases the absolute risk, but not in a way that it will help to predict rAOM accurately...
Immediate adenoidectomy vs initial watchful waiting strategy in children with recurrent upper respiratory tract infections: an economic evaluationChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
JAMA Otolaryngol Head Neck Surg 139:129-33. 2013..To compare the costs associated with 2 clinical strategies in children with recurrent upper respiratory tract infections (URTIs): immediate adenoidectomy vs an initial watchful waiting strategy...
Awareness of, opinions about, and adherence to evidence-based guidelines in otorhinolaryngologyMark C J Aarts
Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 138:148-52. 2012..Guidelines may assist physicians and patients in decisions about effective and safe care. Little is known about the awareness of, opinions about, and adherence to evidence-based guidelines in otolaryngology...
Systemic corticosteroids for acute sinusitisRoderick P Venekamp
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, Utrecht, Netherlands, 3508 GA
Cochrane Database Syst Rev 12:CD008115. 2011..Acute sinusitis is a common reason for patients to seek primary care consultations. The related impairment of daily functioning and quality of life is attributable to symptoms such as facial pain and nasal congestion...
Influence of sampling technique on detection of potential pathogens in the nasopharynxErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:752-5. 2006..To determine the optimal approach for nasopharyngeal culture and to establish which approach children tolerate best...
A systematic review of diagnostic criteria for acute mastoiditis in childrenMaaike T A van den Aardweg
Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otol Neurotol 29:751-7. 2008..To review systematically the literature for the current criteria and strategies used to diagnose acute mastoiditis in children...
Effectiveness of trimethoprim/sulfamethoxazole for children with chronic active otitis media: a randomized, placebo-controlled trialErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, Netherlands
Pediatrics 119:897-904. 2007..The goal was to determine the clinical effectiveness of prolonged outpatient treatment with trimethoprim/sulfamethoxazole for children with chronic active otitis media...
Effect of pneumococcal vaccination on otitis media with effusion in children older than 1 yearThuy My Le
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Eur J Pediatr 166:1049-52. 2007..Therefore, these vaccinations are not indicated in the prevention of OME in these children...
Polymorphisms in the mannan-binding lectin gene are not associated with questionnaire-reported respiratory tract infections in childrenJopje M Ruskamp
Department of Pediatrics, Wilhelmina Children s Hospital, University Medical Center Utrecht, University of Utrecht, Lundlaan 6, Utrecht, The Netherlands
J Infect Dis 198:1707-13. 2008..Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children...
Differences in interaction and subgroup-specific effects were observed between randomized and nonrandomized studies in three empirical examplesAmand F Schmidt
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, PO Box 80082, 3508 TB Utrecht, The Netherlands Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands Electronic address
J Clin Epidemiol 66:599-607. 2013..To determine the comparability of subgroup-specific and interaction effects (differences between subgroups) between different study designs...
[Oral glucocorticoids for acute rhinosinusitis: an RCT]Roderick P Venekamp
Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
Ned Tijdschr Geneeskd 157:A5808. 2013..To determine the efficacy of a short course of oral glucocorticoids in adult patients with acute rhinosinusitis...
Subgroup effects despite homogeneous heterogeneity test resultsRolf H H Groenwold
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
BMC Med Res Methodol 10:43. 2010..Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects...
A small effect of adding antiviral agents in treating patients with severe Bell palsyErwin L van der Veen
Department of Otorhinolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 146:353-7. 2012....
[Effectiveness of adenoidectomy or watchful waiting in children with recurrent upper respiratory tract infections: no differences found in randomised trial]Chantal W B Boonacker
Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
Ned Tijdschr Geneeskd 156:A4380. 2012..To assess the effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections...
The cost-utility of bilateral cochlear implantation: a systematic reviewMarc J W Lammers
Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
Laryngoscope 121:2604-9. 2011..Given this debate, this study's objective was to review the literature on the cost-utility of bilateral cochlear implantation in both children and adults, and study the impact of the used cost and quality-of-life estimates...
Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysisIrene P Jongerden
Department of Medicine, Division of Internal Medicine and Infectious Diseases, Eijkman Winkler Centre for Medical Microbiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
Crit Care Med 35:260-70. 2007..Yet effectiveness regarding patient safety and costs of these systems has not been carefully analyzed...
The diagnostic value of diffusion-weighted magnetic resonance imaging in detecting a residual cholesteatomaMark C J Aarts
Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 143:12-6. 2010....
Interventions in health care professionals to improve treatment in children with upper respiratory tract infectionsChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 74:1113-21. 2010..To assess the effectiveness of these interventions, and when more are effective--which works best. And to analyse the costs associated with these interventions...
A comparison of subgroup analyses in grant applications and publicationsChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Am J Epidemiol 174:219-25. 2011..Both nonreporting prespecified subgroup analyses and reporting post-hoc subgroup analyses are common. More guidance is clearly needed...
Primary stapes surgery in patients with otosclerosis: prediction of postoperative outcomeArnold J N Bittermann
Department of Otorhinolaryngology Head and Neck Surgery, University Medical Center, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 137:780-4. 2011..To evaluate the audiometric results of primary stapes surgery in patients with otosclerosis and to determine predictors of a postoperative air-bone gap (ABG) of 10 dB or less and a postoperative gain in air conduction (AC) exceeding 20 dB...
No evidence for diagnostic value of Mallampati score in patients suspected of having obstructive sleep apnea syndromeSander Bins
Julius Centre for Health Sciences and Primary Care, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 145:199-203. 2011..To analyze whether the Mallampati score is reliable as a simple diagnostic test for predicting obstructive sleep apnea syndrome (OSAS)...
Salvage laryngectomy after primary radiotherapy: what are prognostic factors for the development of pharyngocutaneous fistulae?Mark C J Aarts
Department of Otorhinolaryngology, University Medical Centre Utrecht, The Netherlands
Otolaryngol Head Neck Surg 144:5-9. 2011..g. diabetes mellitus, alcohol consumption, smoking, suture materials and surgical technique used...
Bayes' theorem: a negative example of a RCT on grommets in children with glue earMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, The Netherlands
Eur J Epidemiol 20:23-8. 2005..The results showed that our trial had little or no impact on the beliefs of the ENT-surgeons, i.e. they did not adjust their belief to the extent that was expected according to Bayes' theorem...
The value of a mandibular repositioning appliance for the treatment of nonapneic snoringMark C J Aarts
Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 144:170-3. 2011..No effect on quality of life and daytime sleepiness of partners was found. Furthermore, evidence for sustained long-term effects and complete recovery is lacking...
Chronic suppurative otitis media: a reviewMonique Verhoeff
Department of Otorhinolaryngology (KE04.140.5, Wilhelmina Children's Hospital, University Medical Centre Utrecht, P.O. Box 85090, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 70:1-12. 2006..There is also a need for further well-designed studies on the effectiveness of various management strategies for CSOM...
Remarkable differences between three evidence-based guidelines on management of obstructive sleep apnea-hypopnea syndromeMark C J Aarts
Department of Otorhinolaryngology, University Medical Centre, Utrecht, The Netherlands
Laryngoscope 123:283-91. 2013....
Estimating measures of interaction on an additive scale for preventive exposuresMirjam J Knol
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, GA, Utrecht, The Netherlands
Eur J Epidemiol 26:433-8. 2011..23; 0.49], AP = -0.29 [95%CI: -0.98; 0.40], S = 0.43 [95%CI: 0.07; 2.60]), all indicating negative interaction. Preventive factors should not be used to calculate measures of interaction on an additive scale without recoding...
No evidence for the diagnostic value of Borrelia serology in patients with sudden hearing lossRenée Bakker
Department of Otolaryngology, University Medical Centre, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 146:539-43. 2012..Neuroborreliosis seems to be a rare cause of sudden SHL, and routine screening of patients for borrelia antibodies in serum should therefore not be recommended...
The effect of high dose inhaled corticosteroids on wheeze in infants after respiratory syncytial virus infection: randomised double blind placebo controlled trialMarieke J J Ermers
Department of Paediatric Infectious Diseases, Wilhelmina Children s Hospital, University Medical Centre Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands
BMJ 338:b897. 2009....
A systematic review of analytical methods used to study subgroups in (individual patient data) meta-analysesLaura Koopman
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
J Clin Epidemiol 60:1002-9. 2007..To determine whether individual patient data meta-analyses (IPDMA) are used to perform subgroup analyses and to study whether the analytical methods regarding subgroup analyses differ between IPDMA and conventional meta-analyses (CMA)...
Estimating the attributable mortality of ventilator-associated pneumonia from randomized prevention studiesWilhelmina G Melsen
Julius Center for Health Sciences and Primary Care, the Department of Emergency Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 39:2736-42. 2011..To assess the attributable mortality of ventilator-associated pneumonia using results from randomized controlled trials on ventilator-associated pneumonia prevention...
The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional studyMichiel L Houben
Department of Pediatrics, Wilhelmina Children s Hospital, Utrecht University Medical Center, Utrecht, The Netherlands
PLoS ONE 4:e6572. 2009..The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor...
Penicillin for acute sore throat in children: randomised, double blind trialSjoerd Zwart
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 327:1324. 2003..To assess the effectiveness of penicillin for three days and treatment for seven days compared with placebo in resolving symptoms in children with sore throat...
Ventilator-associated pneumonia and mortality: a systematic review of observational studiesWilhelmina G Melsen
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 37:2709-18. 2009..Ventilator-associated pneumonia is generally believed to increase the mortality of patients. This notion is predominantly based on the results of observational studies...
Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: a systematic reviewDigna M Kamalski
Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 143:181-5. 2010..To identify all disease-specific health-related quality-of-life (HR-QoL) instruments used to assess tinnitus in clinical trials and detail their psychometric properties...
What is the effect of time between sequential cochlear implantations on hearing in adults and children? A systematic review of the literatureYvette E Smulders
Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Laryngoscope 121:1942-9. 2011..This review article investigates the effect of time between sequential cochlear implantations on hearing results in both adults and children...
Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in childrenBirgit K van Staaij
Julius Center for Health Sciences and Primary Care, University Medical Center stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 67:1091-7. 2003..The infrared tympanic membrane thermometer (ITT) seems ideal for measuring central body temperature. Its accuracy, however, is still debated, and the feasibility of daily temperature measurements with an ITT has not been described...
alpha-Blockers to assist stone clearance after extracorporeal shock wave lithotripsy: a meta-analysisYefang Zhu
Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands
BJU Int 106:256-61. 2010..To review the evidence for the use of alpha-blockers after extracorporeal shock wave lithotripsy (ESWL) in enhancing the effectiveness of renal and ureteric stone clearance...
Differences in mortality on the basis of laboratory parameters in an unselected population at the Emergency DepartmentKaren Vroonhof
Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht, The Netherlands
Clin Chem Lab Med 43:536-41. 2005..Therefore, glucose and lactate should be routinely added to a blood gas request. Our study shows differences in mortality for laboratory parameters in patients visiting the emergency department, irrespective of the underlying pathology...
Representativeness of trial populations: an example from a trial of adenotonsillectomy in childrenEmma H van den Akker
Department of Otorhinolaryngology, Wilhelmina Children's Hospital Utrecht, The Netherlands
Acta Otolaryngol 123:297-301. 2003..The trial population appears to be representative of the relevant patient domain, i.e. children currently undergoing adenotonsillectomy in The Netherlands...
Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis mediaCarole N M Brouwer
Department of Paediatrics, Spaarne Hospital, Postbus 770, 2130 AT Hoofddorp, The Netherlands
Qual Life Res 16:1357-73. 2007..Apart from the generic TAIQOL subscales, both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM...
Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trialBirgit K van Staaji
Clin Otolaryngol 30:60-3. 2005..12 children had surgery related complications. CONCLUSION: Adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy has no major clinical benefits over watchful waiting...
Excessive body weight is associated with additional loss of quality of life in children with asthmaRene van Gent
Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
J Allergy Clin Immunol 119:591-6. 2007..Asthma and excessive body weight frequently coexist, whereas the exact relationship between the 2 diseases is unknown...
Long-term effects of pediatric adenotonsillectomy on serum immunoglobulin levels: results of a randomized controlled trialEmma H van den Akker
Department of Otorhinolaryngology, Wilhelmina Children's Hospital/University Medical Center Utrecht, The Netherlands
Ann Allergy Asthma Immunol 97:251-6. 2006..This finding indicates that the remaining mucosa-associated lymphoid tissue can compensate for the loss of tonsil and adenoid tissue...
Health-related quality of life in children with otitis mediaCarole N M Brouwer
Department of Paediatrics, Spaarne Hospital Hoofddorp, Postbus 770, 2130 AT Hoofddorp, The Netherlands
Int J Pediatr Otorhinolaryngol 69:1031-41. 2005....
No differences in physical activity in (un)diagnosed asthma and healthy controlsRene van Gent
Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
Pediatr Pulmonol 42:1018-23. 2007..Childhood asthma does not appear to be associated with a decreased level of daily physical activity in our study population...
Recent advances in otitis media. 1. Epidemiology, natural history, and risk factorsKathleen A Daly
Department of Otolaryngology, University of Minnesota, Minneapolis, USA
Ann Otol Rhinol Laryngol Suppl 194:8-15. 2005
Effect of pneumococcal vaccination on quality of life in children with recurrent acute otitis media: a randomized, controlled trialCarole N M Brouwer
Department of Pediatrics, Spaarne Hospital Haarlem, Haarlem, Netherlands
Pediatrics 115:273-9. 2005..CONCLUSION: Pneumococcal vaccination has no beneficial effect compared with control vaccination on either HRQoL or FHS in children 1 to 7 years old with RAOM...
Otitis media meta-analysisMaroeska M Rovers
Pediatrics 114:508-9; author reply 508-9. 2004
Quality of life in children with undiagnosed and diagnosed asthmaRene van Gent
Department of Pediatrics, Maxima Medical Centre, P O Box 7777, 5500 MB Veldhoven, The Netherlands
Eur J Pediatr 166:843-8. 2007..05), with highest absence rate in those with diagnosed asthma. In conclusion, both undiagnosed and diagnosed asthma have a significant impact on the quality of life of both children and their caregivers...
