D Roos

Summary

Affiliation: University of Amsterdam
Country: The Netherlands

Publications

  1. ncbi Genetic analysis of patients with leukocyte adhesion deficiency: genomic sequencing reveals otherwise undetectable mutations
    Dirk Roos
    Central Laboratory Netherlands Blood Transfusion Service CLB and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Exp Hematol 30:252-61. 2002
  2. ncbi Hematologically important mutations: leukocyte adhesion deficiency
    D Roos
    Department of Experimental Immunohematology, CLB, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Blood Cells Mol Dis 27:1000-4. 2001
  3. ncbi Molecular basis and enzymatic properties of glucose 6-phosphate dehydrogenase volendam, leading to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections
    D Roos
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam, The Netherlands
    Blood 94:2955-62. 1999
  4. pmc Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils
    A T Tool
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
    Biochem J 340:95-101. 1999
  5. ncbi A three-dimensional model system to study the interactions between human leukocytes and endothelial cells
    B C Hakkert
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Eur J Immunol 20:2775-81. 1990
  6. ncbi Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4
    B C Hakkert
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Blood 78:2721-6. 1991
  7. ncbi Monitoring human basophil activation via CD63 monoclonal antibody 435
    E F Knol
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    J Allergy Clin Immunol 88:328-38. 1991
  8. ncbi Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype
    H R Koene
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, and Academic Medical Centre
    Blood 90:1109-14. 1997
  9. pmc 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
    J H Leusen
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    J Exp Med 180:2329-34. 1994
  10. ncbi Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease
    B G Bolscher
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Blood 77:2482-7. 1991

Collaborators

Detail Information

Publications41

  1. ncbi Genetic analysis of patients with leukocyte adhesion deficiency: genomic sequencing reveals otherwise undetectable mutations
    Dirk Roos
    Central Laboratory Netherlands Blood Transfusion Service CLB and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Exp Hematol 30:252-61. 2002
    ....
  2. ncbi Hematologically important mutations: leukocyte adhesion deficiency
    D Roos
    Department of Experimental Immunohematology, CLB, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Blood Cells Mol Dis 27:1000-4. 2001
    ..This article summarizes all known patient mutations and polymorphisms in these genes...
  3. ncbi Molecular basis and enzymatic properties of glucose 6-phosphate dehydrogenase volendam, leading to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections
    D Roos
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam, The Netherlands
    Blood 94:2955-62. 1999
    ....
  4. pmc Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils
    A T Tool
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
    Biochem J 340:95-101. 1999
    ..However, under these latter conditions upregulation of CD11b/CD18 was observed. Taken together, these results suggest that phospholipase D-derived PA is involved in changing the affinity of the CD11b/CD18 integrin for its ligands...
  5. ncbi A three-dimensional model system to study the interactions between human leukocytes and endothelial cells
    B C Hakkert
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Eur J Immunol 20:2775-81. 1990
    ..In summary, we describe a novel leukocyte adhesion/migration method and demonstrate that the contribution of the LeuCAM complex in leukocyte-endothelium interaction varies depending on cell type and stimulus used...
  6. ncbi Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4
    B C Hakkert
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Blood 78:2721-6. 1991
    ....
  7. ncbi Monitoring human basophil activation via CD63 monoclonal antibody 435
    E F Knol
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    J Allergy Clin Immunol 88:328-38. 1991
    ..Thus, MAb 435 is an interesting new tool for investigating the activation of human basophils, in addition to the measurement of mediator release. This MAb may be useful for the detection of basophil activation in vivo...
  8. ncbi Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype
    H R Koene
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, and Academic Medical Centre
    Blood 90:1109-14. 1997
    ..In conclusion, the previously reported differences in IgG binding among the three Fc gammaRIIIa-48L/R/H isoforms are a consequence of the linked, biallelic Fc gammaRIIIa-158V/F polymorphism at amino-acid position 158...
  9. pmc 156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
    J H Leusen
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    J Exp Med 180:2329-34. 1994
    ....
  10. ncbi Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease
    B G Bolscher
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Blood 77:2482-7. 1991
    ..Two histidyl residues were found that might be ligands of the heme iron...
  11. ncbi Gene-scan method for the recognition of carriers and patients with p47(phox)-deficient autosomal recessive chronic granulomatous disease
    J Dekker
    Central Laboratory of the Netherlands Blood Transfusion Service (CLB, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
    Exp Hematol 29:1319-25. 2001
    ..CONCLUSIONS: Our method distinguishes individuals with one NCF1 gene (carriers) from controls and from NCF1-deficient patients...
  12. ncbi Adherence of human neutrophils changes Ca2+ signaling during activation with opsonized particles
    L Koenderman
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam, The Netherlands
    FEBS Lett 270:49-52. 1990
    ..These observations might be of importance for neutrophil function in vivo, since adherence is a prerequisite for diapedesis and chemotaxis...
  13. pmc The impact of platelet-activating factor (PAF)-like mediators on the functional activity of neutrophils: anti-inflammatory effects of human PAF-acetylhydrolase
    T W Kuijpers
    Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Clin Exp Immunol 123:412-20. 2001
    ....
  14. pmc Different proteolytic mechanisms involved in Fc gamma RIIIb shedding from human neutrophils
    P J Middelhoven
    Central Laboratory of the Netherlands Blood Transfusion Service (CLB, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Clin Exp Immunol 125:169-75. 2001
    ....
  15. ncbi Vascular-endothelial-cadherin modulates endothelial monolayer permeability
    P L Hordijk
    Dept of Experimental Immunohematology, CLB and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Amsterdam
    J Cell Sci 112:1915-23. 1999
    ..Together, these data show that monolayer permeability and neutrophil transendothelial migration are modulated by VE-cadherin-mediated cell-cell adhesion, which is in turn controlled by the dynamics of the actin cytoskeleton...
  16. ncbi A rapid turbidimetric assay of phagocytosis and serum opsonizing capacity
    T W Kuypers
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam
    J Immunol Methods 124:85-94. 1989
    ..This assay is applicable to a variety of opsonizing fluids and micro-organisms, and can be used for assessing the phagocytic capacity of patients' neutrophils as well as for assessing the opsonizing capacity of patients' sera...
  17. ncbi Hyper-reactive PMNs in FcgammaRIIa 131 H/H genotype periodontitis patients
    E A Nicu
    Department of Periodontology, Academic Center for Dentistry Amsterdam, Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands
    J Clin Periodontol 34:938-45. 2007
    ..Previous results show that one of the genetic variants of the FcgammaRIIa, the 131 H/H, is associated with more periodontal breakdown than the R/R. This may be due to hyper-reactivity of the H/H-PMNs upon interaction with bacteria...
  18. ncbi Apoptosis of neutrophils
    N A Maianski
    Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Acta Haematol 111:56-66. 2004
    ....
  19. ncbi Influence of tyrosine phosphorylation on protein interaction with FcgammaRIIa
    I Ibarrola
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, University of Amsterdam
    Biochim Biophys Acta 1357:348-58. 1997
    ..We hypothesize that, upon activation, the membrane-associated Lyn is responsible for the initial tyrosine phosphorylation of Fc(gamma)RIIa, thus creating a docking site for Syk and PI 3-kinase...
  20. pmc Molecular diagnosis of chronic granulomatous disease
    D Roos
    Deptartment of Blood Cell Research, Sanquin Blood Supply Organization, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Clin Exp Immunol 175:139-49. 2014
    ....
  21. ncbi Neutrophils enhance eosinophil migration across monolayers of lung epithelial cells
    A E Zuurbier
    Central Laboratory of the Netherlands Blood Transfusion Service, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
    Clin Exp Allergy 31:444-52. 2001
    ..The neutrophils presumably maintain a proper C5a chemotactic gradient in the transmigration model, which results in enhanced eosinophil chemotaxis...
  22. ncbi Beta1 integrin activation on human neutrophils promotes beta2 integrin-mediated adhesion to fibronectin
    J M van den Berg
    CLB, Sanquin Blood Supply Foundation and Laboratory for Experimental and Clinical Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Eur J Immunol 31:276-84. 2001
    ..As transmigrated neutrophils are surrounded by both beta1 and beta2 ligands in the ECM, this integrin cross-talk could play a role in modifying migration and cellular activation in inflamed tissues...
  23. ncbi Clinical and laboratory work-up of patients with neutrophil shortage or dysfunction
    T W Kuijpers
    Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    J Immunol Methods 232:211-29. 1999
    ..A few of the most common causes of neutropenia and neutrophil dysfunctions are described in detail, including recent genetic information regarding the cause of these diseases...
  24. ncbi Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis
    N A Maianski
    Emma Childrens Hospital, Academic Medical Center, University of Amsterdam, The Netherlands
    Cell Death Differ 11:143-53. 2004
    ..We suggest that other proapoptotic factors such as Smac/DIABLO and HtrA2/Omi, which are massively released from the mitochondria, have an important role in neutrophil apoptosis...
  25. ncbi A triallelic Fc gamma receptor type IIIA polymorphism influences the binding of human IgG by NK cell Fc gamma RIIIa
    M de Haas
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    J Immunol 156:2948-55. 1996
    ..Finally, the CD16 mAbs 1D3 and MEM154 bound more strongly and Leu11c (B73.1) bound less to the newly identified Fc gamma RIIIa isoforms...
  26. pmc Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox)
    M de Boer
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Am J Hum Genet 51:1127-35. 1992
    ..In this patient, a G-->A substitution was found at position 1 of intron 4 in the genomic DNA. Therefore, the absence of exon 4 in the cDNA of this patient is due to a splicing error.(ABSTRACT TRUNCATED AT 250 WORDS)..
  27. pmc NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?
    L Van Heerebeek
    Institute of Cardiovascular Research, Free University Medical Center, Amsterdam, The Netherlands
    J Clin Pathol 55:561-8. 2002
    ....
  28. ncbi Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis
    C Meischl
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Apoptosis 11:913-21. 2006
    ..To the best of our knowledge, this is the first demonstration of nuclear NOX2 expression and its involvement in cardiomyocyte apoptosis...
  29. pmc Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans
    M E Stegenga
    Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Diabet Med 25:157-64. 2008
    ..We determined the selective effects of hyperglycaemia and hyperinsulinaemia on lipopolysaccharide (LPS)-induced proinflammatory gene expression and cytokine production in leucocytes and on neutrophil functions...
  30. ncbi Pyrimidine 5'-nucleotidase deficiency: improved detection of carriers
    D de Korte
    Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Clin Chim Acta 184:175-80. 1989
    ..We conclude that analysis of the ribonucleotide patterns, in combination with determination of P5N activity, allows a more accurate diagnosis of heterozygosity for P5N...
  31. ncbi Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils
    W J Lie
    Sanquin Research at CLB, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam
    Clin Exp Allergy 33:1125-34. 2003
    ..LTC4 synthesis by human basophils has been studied quite extensively. However, not much is known about the synthesis of PAF by human basophils...
  32. pmc Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 integrins LFA-1, Mac-1 and p150,95
    J M Shaw
    MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, UK
    Clin Exp Immunol 126:311-8. 2001
    ....
  33. ncbi Mutations of chronic granulomatous disease in Turkish families
    M Y Köker
    Immunology Division, Hacettepe University Children s Hospital, Ankara, Turkey
    Eur J Clin Invest 37:589-95. 2007
    ..The aim of this study was to identify the CGD mutations in a group of Turkish CGD patients and to evaluate the predominance of CGD mutations as X-linked or autosomal recessive (AR) within the Turkish CGD families with known mutations...
  34. ncbi A missense mutation in the heavy subunit of gamma-glutamylcysteine synthetase gene causes hemolytic anemia
    E Ristoff
    Department of Pediatrics, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden
    Blood 95:2193-6. 2000
    ..Several family members with half-normal GCS activity in their erythrocytes were heterozygous for the mutation...
  35. pmc Involvement of Fcgamma receptors and beta2 integrins in neutrophil activation by anti-proteinase-3 or anti-myeloperoxidase antibodies
    D Reumaux
    Département d Hématologie Immunologie Cytogénétique, Centre Hospitalier de Valenciennes, Valenciennes, France
    Clin Exp Immunol 134:344-50. 2003
    ..We therefore conclude that ligation of beta2 integrins rather than adherence per se is essential for this activation, and that TNF-alpha or GM-CSF is needed for priming but not for adherence...
  36. ncbi G-->T transition at cDNA nt 110 (K37Q) in the PKLR (pyruvate kinase) gene is the molecular basis of a case of hereditary increase of red blood cell ATP
    E Beutler
    Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, California 92037, USA
    Hum Mutat 9:282-5. 1997
  37. ncbi Familial deficiency of glutathione reductase in human blood cells
    H Loos
    Blood 48:53-62. 1976
    ..Finally, we found an abnormal oxygen consumption of the propositus' PMNs after phagocytosis of zymosan particles, suggesting that the glutathione reductase reaction was involved in the bactericidal capacity of these cells...
  38. ncbi Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers
    M de Boer
    Central Laboratory, Netherlands Red Cross Blood Transfusion Service, Amsterdam
    Blood 83:531-6. 1994
    ..The carrier state was also manifested by intermediate superoxide production by their intact granulocytes and in the cell-free system...
  39. ncbi Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox
    A Yamauchi
    Department of Host-Defense Biochemistry, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
    Microbiol Immunol 45:249-57. 2001
    ....
  40. ncbi Divergent effects of tumor necrosis factor alpha on apoptosis of human neutrophils
    J M van den Berg
    Central Laboratory of The Netherlands, Blood Transfusion Service Academic Medical Center, University of Amsterdam
    J Leukoc Biol 69:467-73. 2001
    ..These dual, concentration-dependent effects of TNF-alpha provide an explanation for previous controversial reports and support a dominant role for TNF-alpha in neutrophil apoptosis...
  41. ncbi A 40-base-pair duplication in the gp91-phox gene leading to X-linked chronic granulomatous disease
    H Rabbani
    Center for Biotechnology, Karolinska Institute, Novum, Stockholm, Sweden
    Eur J Haematol 51:218-22. 1993
    ..However, the great-grandmother proved to have normal oxidative functions, suggesting that the mutation occurred three generations ago. This is the first description of a nucleotide duplication leading to CGD...