Mathias Prokop

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi Principles of image processing in digital chest radiography
    Mathias Prokop
    The Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht NL 3508 GA, The Netherlands
    J Thorac Imaging 18:148-64. 2003
  2. ncbi Multislice CT: technical principles and future trends
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Eur Radiol 13:M3-13. 2003
  3. ncbi Contrast-enhanced MR Angiography of the renal arteries: blinded multicenter crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3508 GA, The Netherlands
    Radiology 234:399-408. 2005
  4. ncbi General principles of MDCT
    Mathias Prokop
    University Medical Center Utrecht, Department of Radiology, Heidelberglaan 100, NL 3508 GA, Utrecht, The Netherlands
    Eur J Radiol 45:S4-10. 2003
  5. ncbi New challenges in MDCT
    Mathias Prokop
    University Medical Center Utrecht, Department of Radiology, Heidelberglaan 100, Utrecht NL 3508 GA, The Netherlands
    Eur Radiol 15:E35-45. 2005
  6. ncbi Cancer screening with CT: dose controversy
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Eur Radiol 15:D55-61. 2005
  7. doi Dynamic aortic changes in patients with thoracic aortic aneurysms evaluated with electrocardiography-triggered computed tomographic angiography before and after thoracic endovascular aneurysm repair: preliminary results
    Joffrey van Prehn
    Department of Vascular Surgery, University Medical Center, Utrecht, The Netherlands
    Ann Vasc Surg 23:291-7. 2009
  8. doi Lung cancer screening CT-based prediction of cardiovascular events
    Onno M Mets
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    JACC Cardiovasc Imaging 6:899-907. 2013
  9. doi Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up
    Dong Ming Xu
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, Postbus 30 001, 9700 RB Groningen, The Netherlands
    Radiology 250:264-72. 2009
  10. ncbi Does slice thickness affect diagnostic performance of 64-slice CT coronary angiography in stable and unstable angina patients with a positive calcium score?
    Matthijs F L Meijs
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Acta Radiol 51:427-30. 2010

Detail Information

Publications121 found, 100 shown here

  1. ncbi Principles of image processing in digital chest radiography
    Mathias Prokop
    The Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht NL 3508 GA, The Netherlands
    J Thorac Imaging 18:148-64. 2003
    ..Principles of the various algorithms will be explained and their impact on image appearance will be illustrated by clinical examples. Optimum and sub-optimum parameter settings are discussed and pitfalls will be explained...
  2. ncbi Multislice CT: technical principles and future trends
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Eur Radiol 13:M3-13. 2003
    ..Functional and perfusion imaging, as well as advanced image processing and computer-aided diagnosis programs, will add to the possibilities of the next generation of multislice CT scanners...
  3. ncbi Contrast-enhanced MR Angiography of the renal arteries: blinded multicenter crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3508 GA, The Netherlands
    Radiology 234:399-408. 2005
    ..To prospectively and intraindividually compare 0.1 mmol/kg gadobenate dimeglumine with 0.2 mmol/kg gadopentetate dimeglumine for contrast material-enhanced magnetic resonance (MR) angiography of the renal arteries...
  4. ncbi General principles of MDCT
    Mathias Prokop
    University Medical Center Utrecht, Department of Radiology, Heidelberglaan 100, NL 3508 GA, Utrecht, The Netherlands
    Eur J Radiol 45:S4-10. 2003
    ..The article describes how reconstruction of thick multiplanar reformations can be used to take advantage of the 3D capabilities of multislice CT while keep radiation exposure to a minimum...
  5. ncbi New challenges in MDCT
    Mathias Prokop
    University Medical Center Utrecht, Department of Radiology, Heidelberglaan 100, Utrecht NL 3508 GA, The Netherlands
    Eur Radiol 15:E35-45. 2005
    ..Faster effective rotation speeds together with improved dose efficiency of image reconstruction will become the main challenges for cardiac CT imaging...
  6. ncbi Cancer screening with CT: dose controversy
    Mathias Prokop
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Eur Radiol 15:D55-61. 2005
    ..If performed in a dose-conscious fashion, individual risks with lung and colon cancer screening are very small, but estimated population risks are non-negligible...
  7. doi Dynamic aortic changes in patients with thoracic aortic aneurysms evaluated with electrocardiography-triggered computed tomographic angiography before and after thoracic endovascular aneurysm repair: preliminary results
    Joffrey van Prehn
    Department of Vascular Surgery, University Medical Center, Utrecht, The Netherlands
    Ann Vasc Surg 23:291-7. 2009
    ..This may have major implications for correct sizing of the endograft as well as for stent-graft design and durability as the forces on the stents may be much larger after implantation than initially anticipated by stent manufacturers...
  8. doi Lung cancer screening CT-based prediction of cardiovascular events
    Onno M Mets
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    JACC Cardiovasc Imaging 6:899-907. 2013
    ..The aim of this study was to derivate and validate a prediction model for cardiovascular events based on quantification of coronary and aortic calcium volume in lung cancer screening chest computed tomography (CT)...
  9. doi Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up
    Dong Ming Xu
    Department of Radiology, University Medical Center Groningen, Hanzeplein 1, Postbus 30 001, 9700 RB Groningen, The Netherlands
    Radiology 250:264-72. 2009
    ....
  10. ncbi Does slice thickness affect diagnostic performance of 64-slice CT coronary angiography in stable and unstable angina patients with a positive calcium score?
    Matthijs F L Meijs
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Acta Radiol 51:427-30. 2010
    ..Coronary calcification can lead to over-estimation of the degree of coronary stenosis...
  11. ncbi Automated aortic calcium scoring on low-dose chest computed tomography
    Ivana Isgum
    Image Sciences Institute, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    Med Phys 37:714-23. 2010
    ..The authors developed and evaluated a computer-aided system for automatic detection and quantification of aortic calcifications in low-dose noncontrast-enhanced chest CT...
  12. pmc Is there a role for CT coronary angiography in patients with symptomatic angina? Effect of coronary calcium score on identification of stenosis
    Matthijs F L Meijs
    Department of Cardiology, Utrecht University Medical Center, Heidelberglaan 100, Utrecht, The Netherlands
    Int J Cardiovasc Imaging 25:847-54. 2009
    ..In patients with CS <10, CTCA provides excellent diagnostic performance...
  13. doi Comparing coronary artery calcium and thoracic aorta calcium for prediction of all-cause mortality and cardiovascular events on low-dose non-gated computed tomography in a high-risk population of heavy smokers
    Peter C Jacobs
    Julius Center for Health Sciences and Primary Care, Department of Radiology, University Medical Center Utrecht, Netherlands
    Atherosclerosis 209:455-62. 2010
    ..This study compared CAC and TAC as independent predictors of all-cause mortality and cardiovascular events in a population of heavy smokers using low-dose, non-gated CT...
  14. ncbi Automatic segmentation of the pulmonary lobes from fissures, airways, and lung borders: evaluation of robustness against missing data
    Eva M van Rikxoort
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Med Image Comput Comput Assist Interv 12:263-71. 2009
    ..In a second experiment on 100 chest CT scans with incomplete fissures, the method is shown to perform well...
  15. ncbi Toward endografting of the ascending aorta: insight into dynamics using dynamic cine-CTA
    Joffrey van Prehn
    Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands
    J Endovasc Ther 14:551-60. 2007
    ..To evaluate pulsatility and movement along the ascending thoracic aorta using dynamic electrocardiographically-gated 64-slice cine computed tomographic angiography (CTA)...
  16. pmc Diagnosis of chronic obstructive pulmonary disease in lung cancer screening Computed Tomography scans: independent contribution of emphysema, air trapping and bronchial wall thickening
    Onno M Mets
    Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Respir Res 14:59. 2013
    ..Therefore, this study aims to determine the independent diagnostic value of CT emphysema, CT air trapping and CT bronchial wall thickness for COPD in low-dose screening CT scans...
  17. pmc CT air trapping is independently associated with lung function reduction over time
    Onno M Mets
    Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS ONE 8:e61783. 2013
    ..We aimed to study the association between lung function decline and quantitative computed tomography (CT) air trapping...
  18. pmc Unrequested information from routine diagnostic chest CT predicts future cardiovascular events
    Peter C Jacobs
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    Eur Radiol 21:1577-85. 2011
    ..This is the first follow-up study to investigate the prognostic relevance of subclinical coronary (CAC) and aortic calcification (TAC) as contained in routine diagnostic chest CT in a clinical care population...
  19. ncbi Relation of epicardial and pericoronary fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography
    Petra M Gorter
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Cardiol 102:380-5. 2008
    ..Fat surrounding coronary arteries may be involved in the process of coronary atherosclerosis, although this is different for patients with low and high BMIs...
  20. ncbi Image subtraction facilitates assessment of volume and density change in ground-glass opacities in chest CT
    Marius Staring
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Invest Radiol 44:61-6. 2009
    ..To study the impact of image subtraction of registered images on the detection of change in pulmonary ground-glass nodules identified on chest CT...
  21. ncbi Limited value of shape, margin and CT density in the discrimination between benign and malignant screen detected solid pulmonary nodules of the NELSON trial
    Dong Ming Xu
    Department of Radiology, University Medical Center Groningen, University of Groningen, The Netherlands
    Eur J Radiol 68:347-52. 2008
    ..To evaluate prospectively the value of size, shape, margin and density in discriminating between benign and malignant CT screen detected solid non-calcified pulmonary nodules...
  22. doi Coronary artery calcification scoring in low-dose ungated CT screening for lung cancer: interscan agreement
    Peter C A Jacobs
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    AJR Am J Roentgenol 194:1244-9. 2010
    ..We evaluated the interscan agreement of CAC scores from two consecutive low-dose ungated MDCT examinations...
  23. ncbi Automatic segmentation of pulmonary lobes robust against incomplete fissures
    Eva M van Rikxoort
    Image Sciences Institute, 3584 CX, Utrecht, The Netherlands
    IEEE Trans Med Imaging 29:1286-96. 2010
    ..When the fissures are incomplete, an observer study shows agreement of the automatically determined lobe borders with a radiologist for 81% of the lobe borders on average...
  24. doi Early identification of small airways disease on lung cancer screening CT: comparison of current air trapping measures
    Onno M Mets
    Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, HP E01 132, Postbus 85500, 3508 GA, Utrecht, The Netherlands
    Lung 190:629-33. 2012
    ..We studied which of the currently suggested measures is most suitable for detecting functionally relevant air trapping on low-dose computed tomography (CT) in a population of subjects with early-stage disease...
  25. doi Acute pulmonary embolism: effect of a computer-assisted detection prototype on diagnosis--an observer study
    Rianne Wittenberg
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Radiology 262:305-13. 2012
    ..To assess the effect of a computer-assisted detection (CAD) prototype on observer performance for detection of acute pulmonary embolism (PE) with computed tomographic (CT) pulmonary angiography...
  26. ncbi Automatic segmentation of intracranial arteries and veins in four-dimensional cerebral CT perfusion scans
    Adriënne Mendrik
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Med Phys 37:2956-66. 2010
    ..An additional CT perfusion (CTP) scan is acquired of these patients to assess the perfusion of the cerebral tissue. The aim of this study is to extend the diagnostic yield of the CTP scans to also include vascular information...
  27. ncbi Use of dynamic computed tomography to evaluate pre- and postoperative aortic changes in AAA patients undergoing endovascular aneurysm repair
    Arno Teutelink
    Departments of Vascular Surgery, University Medical Center, Utrecht, The Netherlands
    J Endovasc Ther 14:44-9. 2007
    ..To utilize dynamic computed tomographic angiography (CTA) on pre- and postoperative endovascular aneurysm repair (EVAR) patients to characterize cardiac-induced aortic motion within the aneurysm neck, an essential EVAR sealing zone...
  28. doi Distribution of emphysema in heavy smokers: impact on pulmonary function
    Hester A Gietema
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Respir Med 104:76-82. 2010
    ..To investigate impact of distribution of computed tomography (CT) emphysema on severity of airflow limitation and gas exchange impairment in current and former heavy smokers participating in a lung cancer screening trial...
  29. ncbi Computed tomography-quantified emphysema distribution is associated with lung function decline
    Firdaus A A Mohamed Hoesein
    Division of Heart and Lungs Dept of Respiratory Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Eur Respir J 40:844-50. 2012
    ..Heavy (former) smokers with upper lobe-predominant CT-quantified emphysema have a more rapid decrease in lung function than those with lower lobe-predominant CT-quantified emphysema...
  30. ncbi Detection of coronary calcifications from computed tomography scans for automated risk assessment of coronary artery disease
    Ivana Isgum
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Med Phys 34:1450-61. 2007
    ..1 false positives per scan. A calcium score was computed for each scan and subjects were assigned one of four risk categories based on this score. The method assigned the correct risk category to 93.4% of all scans...
  31. ncbi Semiquantitative assessment of cardiovascular disease markers in multislice computed tomography of the chest: interobserver and intraobserver agreements
    Peter C A Jacobs
    Department of Radiology, Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Comput Assist Tomogr 34:279-84. 2010
    ....
  32. doi Computer-aided detection of lung cancer on chest radiographs: effect on observer performance
    Bartjan de Hoop
    Department of Radiology and Image Sciences Institute, University Medical Center, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Radiology 257:532-40. 2010
    ..To assess how computer-aided detection (CAD) affects reader performance in detecting early lung cancer on chest radiographs...
  33. doi Screening for lung cancer with digital chest radiography: sensitivity and number of secondary work-up CT examinations
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 255:629-37. 2010
    ..To estimate the performance of digital chest radiography for detection of lung cancer...
  34. ncbi Multi-atlas-based segmentation with local decision fusion--application to cardiac and aortic segmentation in CT scans
    Ivana Isgum
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 28:1000-10. 2009
    ..Moreover, the additional atlas selection step led to a faster segmentation at a comparable performance...
  35. doi Identification of chronic obstructive pulmonary disease in lung cancer screening computed tomographic scans
    Onno M Mets
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Postbus 85500, 3508GA Utrecht, The Netherlands
    JAMA 306:1775-81. 2011
    ..Smoking is a major risk factor for both cancer and chronic obstructive pulmonary disease (COPD). Computed tomography (CT)-based lung cancer screening may provide an opportunity to detect additional individuals with COPD at an early stage...
  36. ncbi Variability of coronary calcium scores throughout the cardiac cycle: implications for the appropriate use of electrocardiogram-dose modulation with retrospectively gated computed tomography
    Annemarieke Rutten
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan, Utrecht, The Netherlands
    Invest Radiol 43:187-94. 2008
    ....
  37. doi Change in abdominal obesity and risk of coronary calcification
    Siamak Sabour
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Epidemiol Community Health 65:287-8. 2011
    ..A prospective follow-up study was conducted to examine the relationship between 9&emsp14;year change in abdominal obesity and risk of coronary artery calcification (CAC)...
  38. ncbi Potential value of aneurysm sac volume measurements in addition to diameter measurements after endovascular aneurysm repair
    Jasper W van Keulen
    Departments of Vascular Surgery, University Medical Center Utrecht, The Netherlands
    J Endovasc Ther 16:506-13. 2009
    ..To investigate the value of aneurysm sac volume measurement in addition to diameter measurements based on computed tomographic angiography (CTA) after endovascular aneurysm repair (EVAR)...
  39. doi Pulmonary ground-glass nodules: increase in mass as an early indicator of growth
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 255:199-206. 2010
    ..To compare manual measurements of diameter, volume, and mass of pulmonary ground-glass nodules (GGNs) to establish which method is best for identifying malignant GGNs by determining change across time...
  40. ncbi CT-quantified emphysema in male heavy smokers: association with lung function decline
    Firdaus A A Mohamed Hoesein
    Division of Heart and Lungs, Department of Respiratory Medicine, University Medical Centre Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Thorax 66:782-7. 2011
    ..The association between the extent of emphysema in male current and former smokers and lung function decline was investigated...
  41. doi Timing-invariant imaging of collateral vessels in acute ischemic stroke
    Ewoud J Smit
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Stroke 44:2194-9. 2013
    ..We postulate that in these cases collateral vessels are present though not visible on standard imaging techniques that are based on a single time frame...
  42. doi Toward automatic regional analysis of pulmonary function using inspiration and expiration thoracic CT
    Keelin Murphy
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands keelinm gmail com
    Med Phys 39:1650-62. 2012
    ....
  43. doi Pulmonary perifissural nodules on CT scans: rapid growth is not a predictor of malignancy
    Bartjan de Hoop
    Department of Radiology, Rijnstate Hospital, Wagnerlaan 55, 6815 AD, Arnhem, The Netherlands
    Radiology 265:611-6. 2012
    ..To assess the prevalence, natural course, and malignancy rate of perifissural nodules (PFNs) in smokers participating in a lung cancer screening trial...
  44. doi Timing-invariant reconstruction for deriving high-quality CT angiographic data from cerebral CT perfusion data
    Ewoud J Smit
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    Radiology 263:216-25. 2012
    ..To suggest a simple and robust technique used to reconstruct high-quality computed tomographic (CT) angiographic images from CT perfusion data and to compare it with currently used CT angiography techniques...
  45. ncbi Pulmonary nodules: sensitivity of maximum intensity projection versus that of volume rendering of 3D multidetector CT data
    Philipp Peloschek
    Department of Radiology, Vienna Medical University, Wahringer Gurtel 18 20, A 1090 Vienna, Austria Department of Radiology, Utrecht Medical Center, Utrecht, The Netherlands
    Radiology 243:561-9. 2007
    ..To prospectively compare maximum intensity projection (MIP) and volume rendering (VR) of multidetector computed tomographic (CT) data for the detection of small intrapulmonary nodules...
  46. ncbi Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women
    Alexander M de Vos
    Department of Cardiology, University Medical Centre Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
    Eur Heart J 29:777-83. 2008
    ..To determine whether peri-coronary epicardial adipose tissue (EAT) is associated with vascular risk factors and coronary atherosclerosis...
  47. pmc Computer-assisted detection of pulmonary embolism: evaluation of pulmonary CT angiograms performed in an on-call setting
    Rianne Wittenberg
    Department of Radiology, Academic Medical Centre, Amsterdam, The Netherlands
    Eur Radiol 20:801-6. 2010
    ..The purpose of the study was to assess the stand-alone performance of computer-assisted detection (CAD) for evaluation of pulmonary CT angiograms (CTPA) performed in an on-call setting...
  48. doi A comparison of six software packages for evaluation of solid lung nodules using semi-automated volumetry: what is the minimum increase in size to detect growth in repeated CT examinations
    Bartjan de Hoop
    Department of Radiology, University Medical Center, Utrecht, The Netherlands
    Eur Radiol 19:800-8. 2009
    ..5%-25.6%). Segmented volumes of each package were compared to each of the other packages. Systematic volume differences were detected in 11/15 comparisons. This hampers comparison of nodule volumes between software packages...
  49. doi Comparing and combining algorithms for computer-aided detection of pulmonary nodules in computed tomography scans: The ANODE09 study
    Bram van Ginneken
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Med Image Anal 14:707-22. 2010
    ..A method to combine the output of multiple systems is proposed. Results show a substantial performance difference between algorithms, and demonstrate that combining the output of algorithms leads to marked performance improvements...
  50. doi Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD
    Firdaus A A Mohamed Hoesein
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Respir Med 108:136-43. 2014
    ..We hypothesized that it would be possible to discriminate emphysematous, large airway wall thickening and small airways disease dominant phenotypes...
  51. pmc Variation in quantitative CT air trapping in heavy smokers on repeat CT examinations
    Onno M Mets
    Radiology, University Medical Center Utrecht, Heidelberglaan 100, Postbus 85500, 3508 GA, Utrecht, The Netherlands
    Eur Radiol 22:2710-7. 2012
    ..To determine the variation in quantitative computed tomography (CT) measures of air trapping in low-dose chest CTs of heavy smokers...
  52. pmc Visual versus automated evaluation of chest computed tomography for the presence of chronic obstructive pulmonary disease
    Onno M Mets
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS ONE 7:e42227. 2012
    ..We aimed to determine the diagnostic performance of human observers to visually evaluate COPD presence on CT images, in comparison to automated evaluation using quantitative CT measures...
  53. ncbi Monitoring of smoking-induced emphysema with CT in a lung cancer screening setting: detection of real increase in extent of emphysema
    Hester A Gietema
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 244:890-7. 2007
    ....
  54. ncbi Local noise weighted filtering for emphysema scoring of low-dose CT images
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:451-63. 2006
    ..NOVA filtering of a CT image of typically 400 x 512 x 512 voxels takes only a couple of minutes which makes it suitable for routine use in clinical practice...
  55. ncbi Nodule management protocol of the NELSON randomised lung cancer screening trial
    Dong Ming Xu
    Department of Radiology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Lung Cancer 54:177-84. 2006
    ..Furthermore, the quality assurance measures and the NELSON management system (NMS) are presented...
  56. doi Automatic segmentation of pulmonary segments from volumetric chest CT scans
    Eva M van Rikxoort
    Image Sciences Institute, Utrecht, The Netherlands
    IEEE Trans Med Imaging 28:621-30. 2009
    ..The method was able to segment the pulmonary segments with high accuracy (77%), comparable to both interobserver and intraobserver accuracy (74% and 80%, respectively)...
  57. pmc Biphasic contrast medium injection in cardiac CT: moderate versus high concentration contrast material at identical iodine flux and iodine dose
    Annemarieke Rutten
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Radiol 20:1917-25. 2010
    ..To prospectively investigate the influence of contrast material concentration on enhancement in cardiac CT by using a biphasic single-injection protocol...
  58. doi Comparison of frequency of calcified versus non-calcified coronary lesions by computed tomographic angiography in patients with stable versus unstable angina pectoris
    Matthijs F L Meijs
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Cardiol 104:305-11. 2009
    ..No significant relation was found between remodeling index or spotty calcification and UAP. In conclusion, noncalcified plaques and large noncalcified culprit plaques are more frequently found in patients with UAP than in those with SAP...
  59. ncbi Fatty foci in the myocardium in patients with tuberous sclerosis complex: common finding at CT
    Miraude E A P M Adriaensen
    Department of Radiology, Atrium Medical Center, Henri Dunantstraat 5, 6419 PC Heerlen, The Netherlands
    Radiology 253:359-63. 2009
    ..To examine the morphologic characteristics of focal fatty foci in the myocardium of patients with tuberous sclerosis complex (TSC) at computed tomography (CT)...
  60. doi Focal fatty areas in the myocardium of patients with tuberous sclerosis complex: a unique finding
    Miraude E A P M Adriaensen
    Department of Radiology, Atrium Medical Center, Heerlen, The Netherlands
    J Thorac Imaging 26:W12-3. 2011
    ..With this collection of computed tomography and magnetic resonance images, we illustrate a recently described novel finding in the myocardium of patients with tuberous sclerosis complex...
  61. doi Effect of nodule characteristics on variability of semiautomated volume measurements in pulmonary nodules detected in a lung cancer screening program
    Ying Wang
    Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Radiology 248:625-31. 2008
    ..To retrospectively assess volume measurement variability in solid pulmonary nodules (volume, 15-500 mm(3)) detected at lung cancer screening and to quantify the independent effects of nodule morphology, size, and location...
  62. pmc Semi-automatic quantification of subsolid pulmonary nodules: comparison with manual measurements
    Ernst Th Scholten
    Department of Radiology, University Medical Centre Utrecht, Utrecht, The Netherlands Department of Radiology, Kennemer Gasthuis, Haarlem, The Netherlands
    PLoS ONE 8:e80249. 2013
    ..SSNs were previously quantified with time-consuming manual measurements. The aim of the present study is to test the feasibility of semi-automatic SSNs measurements and to compare the results to the manual measurements...
  63. pmc Non-solid lung nodules on low-dose computed tomography: comparison of detection rate between 3 visualization techniques
    Ernst Th Scholten
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Cancer Imaging 13:150-4. 2013
    ..To compare various visualization techniques for the detection of non-solid nodules in low-dose lung cancer screening computed tomography (CT) scans...
  64. ncbi Automatic lung segmentation from thoracic computed tomography scans using a hybrid approach with error detection
    Eva M van Rikxoort
    Image Sciences Institute, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Med Phys 36:2934-47. 2009
    ..In a large quantitative evaluation on a database of 150 scans from different sources, the hybrid method is shown to perform substantially better than a conventional approach at a relatively low increase in computational cost...
  65. doi Frequency and consequences of early in-stent lesions after carotid artery stent placement
    Lisa M Jongen
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan, The Netherlands
    J Vasc Interv Radiol 20:573-9. 2009
    ..To examine the prevalence of in-stent lesions 1 month after carotid artery stent placement with multidetector computed tomography (CT) angiography and to evaluate their possible causes and their consequences during 1-year follow-up...
  66. ncbi Fast noise reduction in computed tomography for improved 3-D visualization
    Michiel Schaap
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 27:1120-9. 2008
    ....
  67. doi Impact of image quality on the performance of computer-aided detection of pulmonary embolism
    Rianne Wittenberg
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands
    AJR Am J Roentgenol 196:95-101. 2011
    ....
  68. ncbi Computer-aided detection of interstitial abnormalities in chest radiographs using a reference standard based on computed tomography
    Yulia Arzhaeva
    Images Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Med Phys 34:4798-809. 2007
    ..The system performance does not significantly differ from that of the observers, when the perihilar regions are excluded from evaluation, and reaches A(z) = 0.85 for the system, with A(z) = 0.88 for both observers...
  69. doi Mature fat cells in the myocardium of patients with tuberous sclerosis complex
    Miraude E A P M Adriaensen
    Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    J Clin Pathol 64:244-5. 2011
    ..The purpose of this study was to investigate if areas of abnormal myocardium in patients with TSC could also be found in post-mortem specimens...
  70. doi TIPS bilateral noise reduction in 4D CT perfusion scans produces high-quality cerebral blood flow maps
    Adriënne M Mendrik
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Phys Med Biol 56:3857-72. 2011
    ..Furthermore, the TIPS bilateral filter is computationally faster than both the 3D and 4D bilateral filters...
  71. doi Detection of occult endoleaks after endovascular treatment of abdominal aortic aneurysm using magnetic resonance imaging with a blood pool contrast agent: preliminary observations
    Sandra A P Cornelissen
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Invest Radiol 45:548-53. 2010
    ..To determine whether blood pool contrast agent-enhanced magnetic resonance imaging (MRI) can visualize endoleaks that are occult on computed tomography (CT) in patients with nonshrinking aneurysms after endovascular aneurysm repair...
  72. ncbi Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syndrome in patients suspected of coronary artery disease
    Petra M Gorter
    Department of Vascular Medicine, University Medical Center Utrecht, F02 126, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Atherosclerosis 197:896-903. 2008
    ..Additionally, we estimated their relationship with obesity and metabolic syndrome in patients suspected of coronary artery disease (CAD)...
  73. ncbi Changes in cerebral perfusion after revascularization of symptomatic carotid artery stenosis: CT measurement
    Annet Waaijer
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Radiology 245:541-8. 2007
    ....
  74. doi On combining computer-aided detection systems
    Meindert Niemeijer
    University Medical Center Utrecht, Image Sciences Institute, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 30:215-23. 2011
    ..For both applications, combination results in a large and significant increase in performance when compared to the best individual CAD system...
  75. pmc Digital chest radiography: an update on modern technology, dose containment and control of image quality
    Cornelia Schaefer-Prokop
    Department of Radiology, Academic Medical Center Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands
    Eur Radiol 18:1818-30. 2008
    ..The focus of the review is hereby on adult applications, the relationship between dose and image quality and the differences between the various detector systems...
  76. ncbi Coronary calcification: effect of small variation of scan starting position on Agatston, volume, and mass scores
    Annemarieke Rutten
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Room E01 132, 3584 CX Utrecht, The Netherlands
    Radiology 246:90-8. 2008
    ..To retrospectively evaluate the effect of a small variation of scan starting position on coronary artery calcium scores based on nonoverlapping 3-mm multidetector computed tomographic (CT) data sets...
  77. ncbi MDCT for the diagnosis of acute pulmonary embolism
    Cornelia Schaefer-Prokop
    Department of Radiology, Academic Medical Center AMC, University of Amsterdam, The Netherlands
    Eur Radiol 15:D37-41. 2005
    ..Diagnostic algorithms are outlined that describe the role of CT in context with the pretest probability, the D-Dimer, lower limb sonography and scintigraphy...
  78. ncbi Automated classification of hyperlucency, fibrosis, ground glass, solid, and focal lesions in high-resolution CT of the lung
    Ingrid C Sluimer
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Med Phys 33:2610-20. 2006
    ..70, 0.53+/-0.02, and 0.40+/-0.03, respectively. The question whether or not a class of abnormality was present in a slice could be answered by the computer system with an accuracy comparable to that of radiologists...
  79. ncbi Pulmonary nodules detected at lung cancer screening: interobserver variability of semiautomated volume measurements
    Hester A Gietema
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 241:251-7. 2006
    ..To retrospectively determine interobserver variability of semiautomated volume measurements of pulmonary nodules and the potential reasons for variability...
  80. ncbi Circle of Willis at CT angiography: dose reduction and image quality--reducing tube voltage and increasing tube current settings
    Annet Waaijer
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 242:832-9. 2007
    ..To prospectively assess the effects of lower tube voltage and various effective tube currents on image quality for computed tomographic (CT) angiography of the circle of Willis...
  81. doi Computer-aided diagnosis in chest radiography: beyond nodules
    Bram van Ginneken
    University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Eur J Radiol 72:226-30. 2009
    ..Recent work in these areas is surveyed, but we conclude that the amount of research devoted to these topics is modest. Reasons for the slow pace of CAD development in chest radiography beyond nodules are discussed...
  82. ncbi Contrast agents in X-ray computed tomography and its applications in oncology
    Annemarieke Rutten
    Department of Radiology, University Medical Center, Utrecht, The Netherlands
    Anticancer Agents Med Chem 7:307-16. 2007
    ..This paper provides a current overview of CT contrast media, CT contrast dynamics, and CT contrast applications with a special focus on oncological imaging...
  83. doi Overranging at multisection CT: an underestimated source of excess radiation exposure
    Arnold Schilham
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiographics 30:1057-67. 2010
    ..Finally, CT examinations should be planned in such a way that radiosensitive organs are as far as possible from the imaged volume...
  84. ncbi Computer analysis of computed tomography scans of the lung: a survey
    Ingrid Sluimer
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:385-405. 2006
    ..In addition, research trends and challenges are identified and directions for future research are discussed...
  85. ncbi Pilot study of dynamic cine CT angiography for the evaluation of abdominal aortic aneurysms: implications for endograft treatment
    Arno Teutelink
    Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands
    J Endovasc Ther 13:139-44. 2006
    ....
  86. ncbi High blood pressure in pregnancy and coronary calcification
    Siamak Sabour
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Hypertension 49:813-7. 2007
    ..04 to 2.37). After adjusting for age, the relation did not change (OR: 1.64; 95% CI: 1.07 to 2.53). We concluded that high blood pressure during pregnancy is associated with an increased risk of coronary calcification later in life...
  87. ncbi Pulmonary nodules: Interscan variability of semiautomated volume measurements with multisection CT-- influence of inspiration level, nodule size, and segmentation performance
    Hester A Gietema
    Department of Radiology, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Radiology 245:888-94. 2007
    ....
  88. ncbi Images in cardiovascular medicine. Multislice computed tomography evaluation 21 years after heterotopic heart transplantation
    Alexander M de Vos
    Heart Lung Center, University Medical Center Utrecht, Utrecht, The Netherlands
    Circulation 113:e57-8. 2006
  89. ncbi Toward automated segmentation of the pathological lung in CT
    Ingrid Sluimer
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:1025-38. 2005
    ..The refined registration scheme enjoys the additional benefit that it does not require pathological (hand-segmented) training data...
  90. doi Intraocular sarcoidosis: association of clinical characteristics of uveitis with positive chest high-resolution computed tomography findings
    Dominique S Clement
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Br J Ophthalmol 94:219-22. 2010
    ..To assess specific clinical criteria in patients with uveitis that are related to signs of sarcoidosis on high-resolution computed tomography (HRCT) of the chest...
  91. ncbi Pulmonary embolism: is multislice CT the method of choice? For
    Ieneke J C Hartmann
    University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Eur J Nucl Med Mol Imaging 32:103-7. 2005
  92. ncbi Computed tomography of the coronary arteries: an alternative?
    Matthijs F L Meijs
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Scand Cardiovasc J 41:277-86. 2007
    ..Although CTCA has clearly left the research environment, the precise role of CTCA in the diagnostic work-up of coronary artery disease needs further research...
  93. ncbi Dose reduction in CT while maintaining diagnostic confidence: diagnostic reference levels at routine head, chest, and abdominal CT--IAEA-coordinated research project
    Virginia Tsapaki
    CT Department, Konstantopoulio Agia Olga Hospital, 1 Ifaistou St, 14569 Anixi, Athens, Greece
    Radiology 240:828-34. 2006
    ..To measure radiation doses for computed tomography (CT) of the head, chest, and abdomen and compare them with the diagnostic reference levels, as part of the International Atomic Energy Agency Research coordination project...
  94. ncbi CT angiography of pulmonary arteries to detect pulmonary embolism: improvement of vascular enhancement with low kilovoltage settings
    Claudia Schueller-Weidekamm
    Department of Radiology, University Hospital of Vienna, Vienna, Austria
    Radiology 241:899-907. 2006
    ....
  95. ncbi Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners
    Marco Das
    Department of Diagnostic Radiology, RWTH Aachen University, Pauwelsstrasse 30, 52072 Aachen, Germany
    Eur Radiol 17:1979-84. 2007
    ..Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies...
  96. ncbi Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON)
    Carola A Van Iersel
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    Int J Cancer 120:868-74. 2007
    ..When pooling with Danish trial data (n = +/-4,000) NELSON is the only trial without screening in controls that is expected to have 80% power to show a lung cancer mortality reduction of at least 25% 10 years after randomisation...
  97. ncbi Comparison of an automatic versus a semiautomatic mode for gray-scale adaptation for digital chest radiography
    Johannes Sailer
    Department of Radiology, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Invest Radiol 39:325-33. 2004
    ..To compare image quality of digital chest radiographs using 2 modes of gradation adjustment...
  98. ncbi Digital radiography of the chest: detector techniques and performance parameters
    Cornelia Schaefer-Prokop
    Department of Radiology, Vienna General Hospital, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Thorac Imaging 18:124-37. 2003
    ..Especially in a PACS environment, CR and DR systems will increasingly substitute for conventional radiography with advantages for CR for bedside chest radiographs and for DR for high-end chest stands...
  99. doi Impact of computed tomography screening for lung cancer on participants in a randomized controlled trial (NELSON trial)
    Karien A M van den Bergh
    Department of Public Health, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Cancer 113:396-404. 2008
    ..In the current study, the authors assessed the discomfort associated with CT scanning and the subsequent wait for results and health-related quality of life (HRQoL) over time...
  100. ncbi Direct detector radiography versus dual reading computed radiography: feasibility of dose reduction in chest radiography
    Michael Gruber
    Department of Radiology and Ludwig Boltzmann Institute for Clinical and Experimental Radiologic Research, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Eur Radiol 16:1544-50. 2006
    ..A further dose reduction does not appear to be feasible for DR without significant loss of image quality...
  101. ncbi Detection of monitoring materials on bedside chest radiographs with the most recent generation of storage phosphor plates: dose increase does not improve detection performance
    Edith Eisenhuber
    Department of Radiology and Ludwig Boltzmann Institute for Clinical and Experimental Radiologic Research, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Radiology 227:216-21. 2003
    ..To evaluate the performance of the most recent generation of storage phosphor plates for the detection of low-contrast catheter material on bedside chest radiographs...