T Plosch

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi request reprint Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice
    Torsten Plosch
    Center for Liver, Digestive, and Metabolic Diseases, Laboratory of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Physiol Gastrointest Liver Physiol 291:G414-23. 2006
  2. ncbi request reprint Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter
    Torsten Plosch
    Center for Liver, Digestive and Metabolic Diseases, Laboratory of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands
    J Nutr 136:2135-40. 2006
  3. ncbi request reprint Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?
    T Plosch
    Center for Liver, Digestive and Metabolic Diseases, Laboratory of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Placenta 28:604-10. 2007
  4. doi request reprint Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice
    Esther M E van Straten
    Dept of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Physiol Endocrinol Metab 297:E1171-8. 2009
  5. doi request reprint The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells: a reason for alterations in preeclampsia?
    T Plosch
    Dept Pediatrics, University Medical Center Groningen, University of Groningen, Center for Liver, Digestive and Metabolic Diseases, Groningen, The Netherlands
    Placenta 31:910-8. 2010
  6. doi request reprint Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism
    E M E Van Straten
    Dept of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen
    Am J Physiol Endocrinol Metab 295:E1341-8. 2008
  7. ncbi request reprint Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice
    V W Bloks
    Departments of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, Groningen University Institute for Drug Exploration, University Hospital Groningen, 9700 RB Groningen, The Netherlands
    J Lipid Res 42:41-50. 2001

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice
    Torsten Plosch
    Center for Liver, Digestive, and Metabolic Diseases, Laboratory of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Physiol Gastrointest Liver Physiol 291:G414-23. 2006
    ..However, our data demonstrate that Abcg5/Abcg8 heterodimer-independent, inducible routes exist that can significantly contribute to total hepatobiliary cholesterol output...
  2. ncbi request reprint Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter
    Torsten Plosch
    Center for Liver, Digestive and Metabolic Diseases, Laboratory of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands
    J Nutr 136:2135-40. 2006
    ..Our data indicate that dietary plant sterols and stanols inhibit cholesterol absorption within the intestinal lumen independently of LXR...
  3. ncbi request reprint Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?
    T Plosch
    Center for Liver, Digestive and Metabolic Diseases, Laboratory of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Placenta 28:604-10. 2007
    ..Here we discuss the potential role of the placenta in the regulation of fetal cholesterol homeostasis and strategies to influence maternal-fetal cholesterol transfer...
  4. doi request reprint Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice
    Esther M E van Straten
    Dept of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Physiol Endocrinol Metab 297:E1171-8. 2009
    ..Despite the profound changes during fetal life, long-term effects appeared to be rather mild and sex selective without modulating the lipid response to a high-fat diet...
  5. doi request reprint The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells: a reason for alterations in preeclampsia?
    T Plosch
    Dept Pediatrics, University Medical Center Groningen, University of Groningen, Center for Liver, Digestive and Metabolic Diseases, Groningen, The Netherlands
    Placenta 31:910-8. 2010
    ..The aim of this study was to characterize the role of LXR alpha/beta in the human placenta under normal physiological circumstances and in preeclampsia...
  6. doi request reprint Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism
    E M E Van Straten
    Dept of Pediatrics, Univ Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen
    Am J Physiol Endocrinol Metab 295:E1341-8. 2008
    ..Despite massive changes in fetal cholesterol metabolism, regulatory mechanisms involved in cholesterol metabolism return to a "normal" state in offspring and allow coping with a high-fat/high-cholesterol diet...
  7. ncbi request reprint Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice
    V W Bloks
    Departments of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, Groningen University Institute for Drug Exploration, University Hospital Groningen, 9700 RB Groningen, The Netherlands
    J Lipid Res 42:41-50. 2001
    ..van Goor, H. Roelofsen, J. Baller, R. Havinga, H. J. Verkade, A. van Tol, P. L. M. Jansen, and F. Kuipers. Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice. J. Lipid Res. 2001. 42: 41;-50...