Candida F Pereira

Summary

Affiliation: University Medical Center
Country: The Netherlands

Publications

  1. ncbi Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions
    C F Pereira
    Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center, Utrecht, The Netherlands
    J Leukoc Biol 68:423-8. 2000
  2. ncbi Enhanced expression of fractalkine in HIV-1 associated dementia
    C F Pereira
    Neuroimmunology Section, Eijkman Winkler Institute, University Medical Center, HpG04 614, Heidelberglaan 100, NL 3584 CX, Utrecht, Netherlands
    J Neuroimmunol 115:168-75. 2001
  3. ncbi APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    J Antimicrob Chemother 51:1181-9. 2003
  4. ncbi Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication
    Candida F Pereira
    Eijkman Winkler Center, HpG04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584, CX Utrecht, The Netherlands
    Antiviral Res 58:253-63. 2003
  5. ncbi Anti-HIV drug development--an overview
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Curr Pharm Des 10:4005-37. 2004
  6. ncbi Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    Int J Antimicrob Agents 25:419-26. 2005

Detail Information

Publications6

  1. ncbi Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions
    C F Pereira
    Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center, Utrecht, The Netherlands
    J Leukoc Biol 68:423-8. 2000
    ..Thus, interactions between HIV-infected monocytes and brain endothelium result in COX-2 expression and, as such, might contribute to the neuropathogenesis of HIV infection...
  2. ncbi Enhanced expression of fractalkine in HIV-1 associated dementia
    C F Pereira
    Neuroimmunology Section, Eijkman Winkler Institute, University Medical Center, HpG04 614, Heidelberglaan 100, NL 3584 CX, Utrecht, Netherlands
    J Neuroimmunol 115:168-75. 2001
    ..We propose that fractalkine produced during interactions between astrocytes and HIV-infected macrophages plays a role in HAD by regulating the trafficking of monocytic cells in the brain parenchyma...
  3. ncbi APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    J Antimicrob Chemother 51:1181-9. 2003
    ..Because of the increasing prevalence of RTI- and PI-resistant HIV-1 strains, the second aim of this study was to assess the antiviral activity of APHS against drug-resistant HIV-1 strains in vitro...
  4. ncbi Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication
    Candida F Pereira
    Eijkman Winkler Center, HpG04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584, CX Utrecht, The Netherlands
    Antiviral Res 58:253-63. 2003
    ..However, APHS did inhibit gag DNA synthesis during reverse transcription in primary cells, which indicates that APHS may target the reverse transcription process...
  5. ncbi Anti-HIV drug development--an overview
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Curr Pharm Des 10:4005-37. 2004
    ....
  6. ncbi Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)
    Candida F Pereira
    Eijkman Winkler Center, HP G04 614, University Medical Center Utrecht, Heidelberglaan 100, NL 3584 CX Utrecht, The Netherlands
    Int J Antimicrob Agents 25:419-26. 2005
    ..These results suggest that APHS is a NNRTI of HIV-1 replication, but not HIV-2 replication, and that APHS is an inhibitor of both HSV-1 and HSV-2 replication...