Research Topics
| P H PeetersSummaryAffiliation: University Medical Center Country: The Netherlands Publications
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Publications
Phytoestrogens and breast cancer risk. Review of the epidemiological evidenceP H M Peeters
Julius Center for Health Studies and Primary Care, University Medical Center Utrecht, The Netherlands
Breast Cancer Res Treat 77:171-83. 2003..None of them found protective effects. However, these prospective studies did not focus on 'age at consumption', which seems to be important based on results from dietary case control studies done so far...
Hypertension, antihypertensive drugs, and mortality from cancer among womenP H Peeters
Julius Center for Patient Oriented Research, Utrecht University, Medical School, Medical Hospital, The Netherlands
J Hypertens 16:941-7. 1998..To investigate whether hypertension and the use of antihypertensive drugs are associated with mortality from cancer among women...
Hypertension and breast cancer risk in a 19-year follow-up study (the DOM cohort). Diagnostic investigation into mammarian cancerP H Peeters
Julius Center for Patient Oriented Research, University Medical Center, Utrecht, The Netherlands
J Hypertens 18:249-54. 2000..To investigate whether hypertension and the use of anti-hypertensive drugs are associated with breast cancer risk...
Prospect-EPIC Utrecht: study design and characteristics of the cohort population. European Prospective Investigation into Cancer and NutritionL K Boker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Eur J Epidemiol 17:1047-53. 2001....
Impact of stereotactic large-core needle biopsy on diagnosis and surgical treatment of nonpalpable breast cancerH M Verkooijen
Department of Surgery, University Medical Center Utrecht, The Netherlands
Eur J Surg Oncol 27:244-9. 2001..In this prospective study, the impact of the introduction of this technique on diagnosis and surgical treatment of nonpalpable breast cancer was assessed in two hospitals in The Netherlands...
Cost comparison between stereotactic large-core-needle biopsy versus surgical excision biopsy in The NetherlandsT Buijs-van der Woude
Julius Center for General Practice and Patient Oriented Research, University Medical Center Utrecht, HP D01.335, PO Box 85500, 3508 GA, Utrecht, The Netherlands
Eur J Cancer 37:1736-45. 2001..Therefore, centralisation of stereotactic equipment for core-needle biopsies would be advisable from an economic perspective...
Seventeen-year evaluation of breast cancer screening: the DOM project, The Netherlands. Diagnostisch Onderzoek (investigation) MammacarcinoomG A Miltenburg
Julius Centre for Patient Oriented Research, Medical School, Utrecht University, The Netherlands
Br J Cancer 78:962-5. 1998..Bias due to the study design may slightly overestimate the protective effect. A screening programme with a 2-yearly, or smaller, interval between successive screens will improve the protection of screening...
The value of 3.0Tesla diffusion-weighted MRI for pelvic nodal staging in patients with early stage cervical cancerW M Klerkx
Department of Gynecology and Obstetrics, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
Eur J Cancer 48:3414-21. 2012....
Determinants of circulating insulin-like growth factor (IGF)-I and IGF binding proteins 1-3 in premenopausal women: physical activity and anthropometry (Netherlands)D W Voskuil
Julius Center for Patient Oriented Research, Utrecht Medical Center, The Netherlands
Cancer Causes Control 12:951-8. 2001..We did confirm that a lean body shape is associated with higher concentrations of IGFBP-1 and IGFBP-2, and possibly also with lower concentrations of IGF-I and IGFBP-3...
Risk factors for cancellation of stereotactic large core needle biopsy on a prone biopsy tableH M Verkooijen
Department of Surgery, Julius Center for Patient Oriented Research, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
Br J Radiol 74:1007-12. 2001..The risk of cancellation of the stereotacic biopsy procedure is considerable in cases of very dense breast tissue or the presence of multiple risk factors...
Consumption of dairy products in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort: data from 35 955 24-hour dietary recalls in 10 European countriesA Hjartåker
Section of Medical Statistics, University of Oslo, PO Box 1122, Blindern, N 0317 Norway
Public Health Nutr 5:1259-71. 2002..To describe and compare the consumption of dairy products in cohorts included in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Increase in breast size after menopause: prevalence and determinantsI Den Tonkelaar
International Health Foundation, Utrecht, The Netherlands
Maturitas 48:51-7. 2004..CONCLUSION: About one in five women experienced an increase in breast size after menopause. The most important factor associated with such an increase was found to be weight gain...
Urinary endogenous sex hormone levels in postmenopausal women after caloric restriction in young adulthoodS G Elias
Julius Center for Health Sciences and Primary Care, University Medical Center, PO Box 85500, Utrecht 3508 GA, The Netherlands
Br J Cancer 90:115-7. 2004..Urinary sex hormone concentrations showed modest elevations with increasing famine exposure. Effects were absent in parous women, but more pronounced in women who had never given birth...
Reproducibility over time of measurements of androgens, estrogens and hydroxy estrogens in urine samples from post-menopausal womenS Rinaldi
International Agency for Research on Cancer, Hormones and Cancer Group, 69372 Lyon, France
Eur J Epidemiol 18:417-24. 2003..85), acceptable for E2, E1 and ADIOL (r > 0.55), but low for 2(OH)-E, 16alpha(OH)-E1 and their ratio (r < 0.46). The adjustment for creatinine concentrations did not increase these correlations...
Urinary endogenous sex hormone levels and the risk of postmenopausal breast cancerN C Onland-Moret
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Room D 01 335, PO Box 85500, 3508 GA Utrecht, The Netherlands
Br J Cancer 88:1394-9. 2003..0-2.3; IRR(testosterone)=1.6, 95% CI: 1.0-2.4; IRR(5alpha-androstane-3alpha, 17beta-diol)=1.7, 95% CI: 1.1-2.7). In conclusion, women with higher excretion levels of both oestrogens and androgens have an increased risk of breast cancer...
Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutritionR Kaaks
International Agency for Research on Cancer IARC WHO, Lyon, France
Endocr Relat Cancer 12:1071-82. 2005..The results from this study caution against the use of DHEA(S), or other androgens, for postmenopausal androgen replacement therapy...
Patterns of alcohol consumption in 10 European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) projectS Sieri
Epidemiology Unit, National Cancer Institute, Via Venezian 1, 20133 Milan, Italy
Public Health Nutr 5:1287-96. 2002..These centres, in 10 European countries, are characterised by widely differing drinking habits and frequencies of alcohol-related diseases...
Heritable aspects of dysplastic breast glandular tissue (DY)G Haars
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
Breast Cancer Res Treat 87:149-56. 2004..These result indicate a substantial genetic influence on DY, but with a possible modifying ability of other factors, such as parity...
Age at menarche in relation to adult height: the EPIC studyN C Onland-Moret
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Epidemiol 162:623-32. 2005..13-0.50 cm). Based on time trends, more recent birth cohorts have their menarche earlier and grow taller. However, women with earlier menarche reach a shorter adult height compared with women who have menarche at a later age...
Plasma carotenoids as biomarkers of intake of fruits and vegetables: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)W K Al-Delaimy
Nutrition and Hormones Group, International Agency for Research on Cancer (IARC-WHO, Lyon, France
Eur J Clin Nutr 59:1397-408. 2005..Fruits and vegetables measured by 24HDR were generally better able to predict plasma carotenoids at the ecological level...
IGF-I, IGFBP-3 and breast cancer risk in women: The European Prospective Investigation into Cancer and Nutrition (EPIC)S Rinaldi
International Agency for Research on Cancer (IARC-WHO, 150 cours Albert Thomas, 69372 Lyon, , France
Endocr Relat Cancer 13:593-605. 2006....
Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European womenT Norat
International Agency for Research on Cancer, Lyon, France
Eur J Clin Nutr 61:91-8. 2007..The aim of this study was to examine the relationship of diet with serum insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in women...
HFE mutations and risk of coronary heart disease in middle-aged womenD L van der A
University Medical Center Utrecht, The Netherlands
Eur J Clin Invest 36:682-90. 2006..We used data of a cohort of 15 236 Dutch middle-aged women to investigate whether C282Y carriers and H63D carriers are at increased risk of coronary heart disease compared with non-carriers...
Risk of acute ischemic heart disease in postmenopausal women depends on von Willebrand factor and fibrinogen concentrations, and blood group genotypeM Roest
J Thromb Haemost 5:189-91. 2007
Hormone replacement therapy, mammography screening and changing age-specific incidence rates of breast cancer: an ecological study comparing two European populationsH M Verkooijen
Geneva Cancer Registry, Institute for Social and Preventive Medicine, Geneva University, 55 Boulevard de la Cluse, Geneva 1205, Switzerland
Breast Cancer Res Treat 107:389-95. 2008....
Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST)J B A Crusius
Laboratory of Immunogenetics, Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
Ann Oncol 19:1894-902. 2008..The relative contribution to gastric cancer (GC) risk of variants in genes that determine the inflammatory response remains mostly unknown and results from genotyping studies are inconsistent...
Consumption of added fats and oils in the European Prospective Investigation into Cancer and Nutrition (EPIC) centres across 10 European countries as assessed by 24-hour dietary recallsJ Linseisen
Unit of Human Nutrition and Cancer Prevention, Technical University of Munich, Alte Akademie 16, D 85350 Freising Weihenstephan, Germany
Public Health Nutr 5:1227-42. 2002..To evaluate the consumption of added fats and oils across the European centres and countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Soy product consumption in 10 European countries: the European Prospective Investigation into Cancer and Nutrition (EPIC) studyL Keinan-Boker
Julius Center for General Practice and Patient Oriented Research, DO1 335, University Medical Centre Utrecht UMCU, PO Box 85500, The Netherlands
Public Health Nutr 5:1217-26. 2002..A subsidiary aim was to characterise the pattern of soy consumption among a sub-group of participants with a habitual health-conscious lifestyle (HHL), i.e. non-meat eaters who are fish eaters, vegetarians and vegans...
The 1944-1945 Dutch famine and age at natural menopause--the value and validity of individual exposure assessmentS G Elias
Julius Center for General Practice and Patient Oriented Research, University Medical Center Utrecht, The Netherlands
IARC Sci Publ 156:311-3. 2002
Consumption of soy products in 10 European countriesBoker L Keinan
Julius Center for General Practice and Patient Oriented Research, Utrecht, The Netherlands
IARC Sci Publ 156:105-8. 2002
Consumption of soy products among European consumers of a health-conscious dietBoker L Keinan
Julius Center for General Practice and Patient Oriented Research, Utrecht, The Netherlands
IARC Sci Publ 156:109-12. 2002
Age at menarche in relation to adult height in the EPIC cohortN C Moret
Julius Center for General Practice and Patient Oriented Research, UMC Utrecht, The Netherlands
IARC Sci Publ 156:307-9. 2002
Phytoestrogens and breast cancer risk: review of the epidemiological evidenceP H M Peeters
Julius Center for General Practice and Patient-Oriented Research, University Medical Center Utrecht, The Netherlands
IARC Sci Publ 156:331-6. 2002
Age at exposure to the Dutch famine of 1944-1945 has opposing effects on adult mammographic density (DY); a study in the DOM cohortP A H van Noord
Julius Center for General Practice and Patient-Oriented Research, University Medical Center Utrecht, Utrecht, The Netherlands
IARC Sci Publ 156:541-2. 2002
Cooking of meat and fish in Europe--results from the European Prospective Investigation into Cancer and Nutrition (EPIC)S Rohrmann
Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Eur J Clin Nutr 56:1216-30. 2002..Since data on food cooking methods are scarce, the aim of this study was to describe the variation in meat and fish cooking methods in different parts of Europe...
European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collectionE Riboli
Unit of Nutrition and Cancer, International Agency for Research on Cancer IARC WHO, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
Public Health Nutr 5:1113-24. 2002..The present paper provides a description of the EPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort...
Food sources of carbohydrates in a European cohort of adultsE Wirfalt
Department of Medicine, Lund University, Malmo, SE 20502 Sweden
Public Health Nutr 5:1197-215. 2002..To describe the average consumption of carbohydrate-providing food groups among study centres of the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Trends in self-reported past alcoholic beverage consumption and ethanol intake from 1950 to 1995 observed in eight European countries participating in the European Investigation into Cancer and Nutrition (EPIC)K Klipstein-Grobusch
Department of Epidemiology, German Institute of Human Nutrition, Arthur Scheunert Allee 114 116, D 14558 Potsdam Rehbrücke, Germany
Public Health Nutr 5:1297-310. 2002..To describe the trends of self-reported past consumption of alcoholic beverages and ethanol intake from 1950 to 1995 within the European Prospective Investigation into Cancer and Nutrition (EPIC)...
European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study: rationale, design and population characteristicsN Slimani
Unit of Nutrition and Cancer, International Agency for Research on Cancer IARC WHO, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
Public Health Nutr 5:1125-45. 2002..The overall results suggest that, after adjustment for age, dietary intakes estimated from calibration samples can reasonably be interpreted as representative of the main cohorts in most of the EPIC centres...
Consumption of vegetables, fruit and other plant foods in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countriesA Agudo
Department of Epidemiology, Catalan Institute of Oncology ICO, 08907 L Hospitalet de Llobregat, Barcelona, Spain
Public Health Nutr 5:1179-96. 2002..To describe and compare the consumption of the main groups and sub-groups of vegetables and fruits (V&F) in men and women from the centres participating in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Interobserver variability between general and expert pathologists during the histopathological assessment of large-core needle and open biopsies of non-palpable breast lesionsH M Verkooijen
Department of Surgery, University Medical Center Utrecht, The Netherlands
Eur J Cancer 39:2187-91. 2003..Additionally, the risk of benign/malignant inconsistencies between general pathologists and experts was approximately 1 in 55 for both needle and open biopsies...
Reliability of biomarkers of iron status, blood lipids, oxidative stress, vitamin D, C-reactive protein and fructosamine in two Dutch cohortsW K Al-Delaimy
International Agency for Research on Cancer IARC WHO, Lyon, France
Biomarkers 11:370-82. 2006..With the exception of a few gender-specific differences, most of the 20 biomarkers performed well and can be considered to have sufficient reliability to be used in future cohort studies...
Physical activity of subjects aged 50-64 years involved in the European Prospective Investigation into Cancer and Nutrition (EPIC)M Haftenberger
German Institute of Human Nutrition, Department of Epidemiology, Arthur Scheunert Allee 114 116, D 14558 Potsdam Rehbrücke, Germany
Public Health Nutr 5:1163-76. 2002..To describe physical activity of participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Stereotactic large core needle biopsy for all nonpalpable breast lesions?L E Hoorntje
Department of Surgery, University Medical Centre, Utrecht, The Netherlands
Breast Cancer Res Treat 73:177-82. 2002..We studied differences in cancer prevalence between a group of women referred through the national screening program and a non-screening group, and assessed whether the validity of SLCNB differed between these groups...
The EPIC nutrient database project (ENDB): a first attempt to standardize nutrient databases across the 10 European countries participating in the EPIC studyN Slimani
Nutrition and Hormones Group, International Agency for Research on Cancer, Lyon, France
Eur J Clin Nutr 61:1037-56. 2007..This was required because there is currently no European reference NDB available...
Diagnosing non-palpable breast disease: short-term impact on quality of life of large-core needle biopsy versus open breast biopsyH M Verkooijen
Department of Surgery, University Medical Center, Utrecht, The Netherlands
Surg Oncol 10:177-81. 2002..In this prospective study, the quality of life of patients undergoing large-core needle biopsy was compared with that of patients undergoing open breast biopsy prior to learning the definitive diagnosis...
Relationship of serum antimüllerian hormone concentration to age at menopauseJ van Disseldorp
University Medical Center Utrecht, Utrecht, The Netherlands
J Clin Endocrinol Metab 93:2129-34. 2008..However, AMH, unlike antral follicle counts, has not been tested as yet as a predictor of reproductive status. By relating AMH levels to the age distribution of reproductive events like onset of menopause, we tested this hypothesis...
Introduction of sentinel node biopsy and stage migration of breast cancerM van der Heiden-van der Loo
Comprehensive Cancer Centre Middle Netherlands, Postbus 19079, 3501 DB Utrecht, The Netherlands
Eur J Surg Oncol 32:710-4. 2006....
[Stereotactic large core needle biopsy for the diagnosis of nonpalpable breast lesions: reliable without additional excision biopsy]L E Hoorntje
afd. Heelkunde, Universitair Medisch Centrum Utrecht, Postbus 85.500, 3508 GA Utrecht
Ned Tijdschr Geneeskd 147:868-73. 2003..CONCLUSION: No malignancies were missed during the limited follow-up period, and therefore, to date, the sensitivity of SLCNB seems to be comparable to that estimated in the study setting...
Body mass index, waist circumference and waist-hip ratio and serum levels of IGF-I and IGFBP-3 in European womenI T Gram
Institute of Community Medicine, School of Medicine, University of Troms, Troms, Norway
Int J Obes (Lond) 30:1623-31. 2006..Serum IGFBP-3 was positively related to central adiposity. These suggest that bioavailable IGF-I levels could be lower in obese compared to non-obese women and inversely related to central adiposity...
Diagnostic accuracy for different strategies of image-guided breast intervention in cases of nonpalpable breast lesionsR M Pijnappel
Department of Radiology, Martini Hospital, locatie Van Swieten, PO Box 30033, 9700 RM Groningen, The Netherlands
Br J Cancer 90:595-600. 2004..Ultrasound-guided intervention can be performed in a large percentage of nonpalpable lesions. Lesions consisting only of microcalcifications on mammography need special attention...
Reproducibility of mammographic classifications for non-palpable suspect lesions with microcalcificationsR M Pijnappel
Department of Radiology, Martini Hospital, locatie Van Swieten, PO Box 30033, 9700 RM Groningen, The Netherlands
Br J Radiol 77:312-4. 2004..The clinical management (follow-up or biopsy) of non-palpable lesions consisting of microcalcifications depending upon radiological classification in the groups BI-RADS 3 (follow-up) and BI-RADS 4 (biopsy) is therefore debatable...
Total and cause specific mortality among Swedish women with cosmetic breast implants: prospective studyV C M Koot
Julius Centre for Health Sciences and Primary Care, University Medical Centre, Box 85500, 3508 GA Utrecht, Netherlands
BMJ 326:527-8. 2003
Warthin's tumour and smokingJ A de Ru
Department of Otolaryngology - Head and Neck Surgery, University Medical Centre, Utrecht, Netherlands
B-ENT 1:63-6. 2005..6 for the pleomorphic adenoma group. CONCLUSION: The mean age for the development of a Warthin's tumour is ten years older than for a pleomorphic adenoma. Furthermore, the development seems to be closely related to smoking habits...
Vacuum-assisted breast biopsy: a critical reviewL E Hoorntje
Department of Surgery, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Eur J Cancer 39:1676-83. 2003..The results of this review indicate that vacuum-assisted biopsy can decrease the high-risk and DCIS underestimate rates, but it is unclear whether it can also decrease the miss-rates of cancer...
Overweight, obesity and fat distribution in 50- to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)M Haftenberger
Department of Epidemiology, German Institute of Human Nutrition, Arthur Scheunert Allee 114 116, D 14558 Potsdam Rehbrücke, Germany
Public Health Nutr 5:1147-62. 2002..To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC)...
Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)W K Al-Delaimy
International Agency for Research on Cancer (IARC-WHO, Lyon, France
Eur J Clin Nutr 59:1387-96. 2005..At individual subject levels, FQ measurements of fruits, root vegetables and carrots, and tomato products are, respectively, good predictors of beta-cryptoxanthin, alpha-carotene, and lycopene in plasma...
Diagnostic strategies in non-palpable breast lesionsR M Pijnappel
Department of Radiology, Martini Hospital, locatie Van Swieten, PO Box 30033, 9700 RM, Groningen, The Netherlands
Eur J Cancer 38:550-5. 2002..These figures obtained from routine daily practice show the importance of protocols in order to standardise diagnostic procedures and prevent unnecessary surgery...
Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC studyF Canzian
International Agency for Research on Cancer, Lyon, France
Br J Cancer 94:299-307. 2006..Common genetic variation in these candidate genes does not play a major role in altering breast cancer risk in Caucasians...
Relationship of alcohol intake and sex steroid concentrations in blood in pre- and post-menopausal women: the European Prospective Investigation into Cancer and NutritionS Rinaldi
International Agency for Research on Cancer, 150 cours Albert Thomas, 69372, Lyon Cedex, France
Cancer Causes Control 17:1033-43. 2006....
Research Grants
- Variations in plasma phytoestrogen levels in EuropePetra Peeters; Fiscal Year: 2004..This pilot study will determine whether the variation of phytoestrogen concentrations in the European EPIC population is sufficient to justify further large-scale prospective nested case-control studies. ..
