Willem M Lijfering

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi Mesenteric vein thrombosis associated with primary cytomegalovirus infection: a case report
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, University Medical Center Groningen, Groningen, The Netherlands
    Blood Coagul Fibrinolysis 18:509-11. 2007
  2. doi Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives
    Willem M Lijfering
    Department of Hematology, University Medical Center Groningen, The Netherlands
    Blood 113:5314-22. 2009
  3. doi Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A
    Willem M Lijfering
    Division of Hemostasis and Thrombosis, Department of Hematology, University Medical Center Groningen, The Netherlands
    Circulation 121:1706-12. 2010
  4. doi Clinical relevance of decreased free protein S levels: results from a retrospective family cohort study involving 1143 relatives
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Blood 113:1225-30. 2009
  5. doi Relationship between progression to AIDS and thrombophilic abnormalities in HIV infection
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology and Division of Infectious Diseases, Department of Internal Medicine, University Medical Center Groningen UMCG, Groningen, The Netherlands
    Clin Chem 54:1226-33. 2008
  6. doi Possible contribution of cytomegalovirus infection to the high risk of (recurrent) venous thrombosis after renal transplantation
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Thromb Haemost 99:127-32. 2008
  7. ncbi The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Haematologica 92:1703-6. 2007
  8. ncbi The risk of venous and arterial thrombosis in hyperhomocysteinaemia is low and mainly depends on concomitant thrombophilic defects
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Thromb Haemost 98:457-63. 2007
  9. doi Associations between high factor VIII and low free protein S levels with traditional arterial thrombotic risk factors and their risk on arterial thrombosis: results from a retrospective family cohort study
    Rene Mulder
    Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, The Netherlands
    Thromb Res 126:e249-54. 2010
  10. pmc Different risk of deep vein thrombosis and pulmonary embolism in carriers with factor V Leiden compared with non-carriers, but not in other thrombophilic defects. Results from a large retrospective family cohort study
    Anja B U Mäkelburg
    Division of Hemostasis and Thrombosis, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Haematologica 95:1030-3. 2010

Collaborators

Detail Information

Publications15

  1. ncbi Mesenteric vein thrombosis associated with primary cytomegalovirus infection: a case report
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, University Medical Center Groningen, Groningen, The Netherlands
    Blood Coagul Fibrinolysis 18:509-11. 2007
    ..We discuss the possible mechanisms of cytomegalovirus-related venous thrombosis...
  2. doi Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives
    Willem M Lijfering
    Department of Hematology, University Medical Center Groningen, The Netherlands
    Blood 113:5314-22. 2009
    ....
  3. doi Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A
    Willem M Lijfering
    Division of Hemostasis and Thrombosis, Department of Hematology, University Medical Center Groningen, The Netherlands
    Circulation 121:1706-12. 2010
    ..Homozygous or double heterozygous factor V Leiden and/or prothrombin G20210A is a rare inherited thrombophilic trait. Whether individuals with this genetic background have an increased risk of recurrent venous thrombosis is uncertain...
  4. doi Clinical relevance of decreased free protein S levels: results from a retrospective family cohort study involving 1143 relatives
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Blood 113:1225-30. 2009
    ..03-8.5) and 3.4 (95% CI, 1.1-10.3). In conclusion, free protein S level can identify young subjects at risk for venous thrombosis in thrombophilic families, although the cutoff level lies far below the normal range in healthy volunteers...
  5. doi Relationship between progression to AIDS and thrombophilic abnormalities in HIV infection
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology and Division of Infectious Diseases, Department of Internal Medicine, University Medical Center Groningen UMCG, Groningen, The Netherlands
    Clin Chem 54:1226-33. 2008
    ..We hypothesized that acquired thrombophilic abnormalities that could predispose to thrombosis are most pronounced in patients in advanced stages of HIV infection...
  6. doi Possible contribution of cytomegalovirus infection to the high risk of (recurrent) venous thrombosis after renal transplantation
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Thromb Haemost 99:127-32. 2008
    ..Prospective studies are warranted to establish this observation, which suggests that CMV infection influences the high risk of (recurrent) venous thrombosis in renal transplant recipients...
  7. ncbi The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Haematologica 92:1703-6. 2007
    ..3 (CI 0.2-9.8) and no relatives had arterial thrombosis. We conclude that it is likely that the increased risk of venous and arterial thrombosis in hyperhomocysteinemia is mainly related to elevated FVIII levels...
  8. ncbi The risk of venous and arterial thrombosis in hyperhomocysteinaemia is low and mainly depends on concomitant thrombophilic defects
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Thromb Haemost 98:457-63. 2007
    ..Concomitant thrombophilic defects are probably main determinants on the risk of venous thrombosis, rather than hyperhomocysteinaemia itself...
  9. doi Associations between high factor VIII and low free protein S levels with traditional arterial thrombotic risk factors and their risk on arterial thrombosis: results from a retrospective family cohort study
    Rene Mulder
    Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, The Netherlands
    Thromb Res 126:e249-54. 2010
    ..Whether high factor (F)VIII and low free protein S levels are risk factors for arterial thrombosis is unclarified...
  10. pmc Different risk of deep vein thrombosis and pulmonary embolism in carriers with factor V Leiden compared with non-carriers, but not in other thrombophilic defects. Results from a large retrospective family cohort study
    Anja B U Mäkelburg
    Division of Hemostasis and Thrombosis, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Haematologica 95:1030-3. 2010
    ..5-14.4) for pulmonary embolism. For other thrombophilic defects no such effect was observed. Thus the FVL paradox was confirmed in our study. However, a similar paradox in carriers of other thrombophilic defects was not observed...
  11. doi A lower risk of recurrent venous thrombosis in women compared with men is explained by sex-specific risk factors at time of first venous thrombosis in thrombophilic families
    Willem M Lijfering
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Groningen, The Netherlands
    Blood 114:2031-6. 2009
    ....
  12. ncbi High long-term absolute risk of recurrent venous thromboembolism in patients with hereditary deficiencies of protein S, protein C or antithrombin
    Jan Leendert P Brouwer
    Division of Haemostasis, Thrombosis and Rheology, Department of Hematology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Thromb Haemost 101:93-9. 2009
    ..This risk is increased after a first spontaneous event, and by concomitance of other thrombophilic defects...
  13. doi Venous thromboembolism in HIV-positive women during puerperium: a case series
    J Marije Jansen
    Department of Obstetrics and Gynaecology, University Medical Center Groningen, Groningen, The Netherlands
    Blood Coagul Fibrinolysis 19:95-7. 2008
    ..Further clinical studies are warranted to assess its implications for pregnancy and postpartum management in HIV-infected women...
  14. doi Increased risk of arterial thromboembolism after a prior episode of venous thromboembolism: results from the Prevention of REnal and Vascular ENd stage Disease (PREVEND) Study
    Inge M van Schouwenburg
    Division of Haemostasis and Thrombosis, Department of Haematology, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, Groningen, The Netherlands
    Br J Haematol 159:216-22. 2012
    ..This study showed that subjects with venous thromboembolism are at increased risk for arterial thromboembolism, particularly in the first year after venous thromboembolism and after an unprovoked event...
  15. doi Statin use in patients with nephrotic syndrome is associated with a lower risk of venous thromboembolism
    Mohammad Resh
    Division of Hemostasis and Thrombosis, Department of Hematology, University Medical Center Groningen, The Netherlands
    Thromb Res 127:395-9. 2011
    ..In non-renal populations, statins are associated with lower risk of VTE. Hence, we set up this single-center retrospective cohort study to assess whether statin use influenced VTE risk in NS subjects...