Research Topics
| Maurine A Leverstein-van HallSummaryAffiliation: University Medical Center Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Extensive hospital-wide spread of a multidrug-resistant enterobacter cloacae clone, with late detection due to a variable antibiogram and frequent patient transferMaurine A Leverstein-van Hall
Eijkman Winkler Institute for Microbiology, Infectious Disease and Inflammation, University Hospital Utrecht, Rm G 04 614, PO 855000, 3508 GA Utrecht, The Netherlands
J Clin Microbiol 44:518-24. 2006..These findings suggest that computerized tools for surveillance may recognize resistance trends that are too complex to be detected by manual review and indicate the need for prospective evaluation of such algorithms...
Multidrug resistance among Enterobacteriaceae is strongly associated with the presence of integrons and is independent of species or isolate originMaurine A Leverstein-van Hall
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Centre, Utrecht, The Netherlands
J Infect Dis 187:251-9. 2003..The acquisition of resistance genes is not random, and the transfer of integron-carrying elements plays a dominant role in the development of MDR by Enterobacteriaceae...- Evaluation of the Etest ESBL and the BD Phoenix, VITEK 1, and VITEK 2 automated instruments for detection of extended-spectrum beta-lactamases in multiresistant Escherichia coli and Klebsiella sppMaurine A Leverstein-van Hall
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center Utrecht, Room G04 614, PO Box 85000, 3508 GA Utrecht, The Netherlands
J Clin Microbiol 40:3703-11. 2002.... - Presence of integron-associated resistance in the community is widespread and contributes to multidrug resistance in the hospitalM A Leverstein-Van Hall
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center, Utrecht, The Netherlands
J Clin Microbiol 40:3038-40. 2002.... - Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant Enterobacteriaceae in a clinical settingMaurine A Leverstein-van Hall
Eijkman Winkler Institute for Microbiology, Infectious Diseases, and Inflammation, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
J Infect Dis 186:49-56. 2002..These findings provide strong evidence that the horizontal transfer of resistance genes contributed largely to the emergence of multidrug-resistant Enterobacteriaceae in this clinical setting... - Control of nosocomial multiresistant Enterobacteriaceae using a temporary restrictive antibiotic agent policyM A Leverstein-Van Hall
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Centre Utrecht, The Netherlands
Eur J Clin Microbiol Infect Dis 20:785-91. 2001..In the years since, the incidence has remained at this low level, and the antibiotic costs have decreased to a level lower than before intervention... 
The role of intestinal colonization with gram-negative bacteria as a source for intensive care unit-acquired bacteremiaEvelien A N Oostdijk
Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 39:961-6. 2011..We quantified the role of intestinal tract carriage with gram-negative bacteria and intensive care unit-acquired gram-negative bacteremia...- Failure to control an outbreak of qnrA1-positive multidrug-resistant Enterobacter cloacae infection despite adequate implementation of recommended infection control measuresArmand Paauw
Eijkman Winkler Center for Microbiology, Infectious Diseases and Inflammation, Department of Hospital Hygiene and Infection Prevention, University Medical Center Utrecht, Utrecht, The Netherlands
J Clin Microbiol 45:1420-5. 2007..Strategies to identify such strains in an early phase and adapted guidelines for such "superbugs" are needed to prevent these clones from becoming endemic... - Enterobacter cloacae outbreak and emergence of quinolone resistance gene in Dutch hospitalArmand Paauw
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
Emerg Infect Dis 12:807-12. 2006..On the same plasmid, 2 other class 1 integrons were present. One was a new integron associated with the bla(CTX-M-9) extended-spectrum beta-lactamase... - Identification of resistance and virulence factors in an epidemic Enterobacter hormaechei outbreak strainArmand Paauw
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
Microbiology 155:1478-88. 2009..The high number of genes detected in the EHOS that were related to transferable elements reflects the genomic plasticity of the E. cloacae complex and may explain the emergence of the EHOS in the hospital environment... - Antibiotic exposure and resistance development in Pseudomonas aeruginosa and Enterobacter species in intensive care unitsDavid S Y Ong
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 39:2458-63. 2011..We quantified the association between antibiotic exposure and acquisition of antibiotic resistance in Pseudomonas aeruginosa and Enterobacter species in intensive care unit patients... - Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strainsM A Leverstein-Van Hall
Department of Medical Microbiology, University Medical Centre Utrecht, The Netherlands
Clin Microbiol Infect 17:873-80. 2011..coli genotypes also present in human samples. These findings are suggestive for transmission of ESBL genes, plasmids and E. coli isolates from poultry to humans, most likely through the food chain... - Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover studyAnne Marie G A de Smet
Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
Lancet Infect Dis 11:372-80. 2011..In this analysis, we aimed to assess effectiveness of these interventions for prevention of respiratory tract colonisation and bacteraemia with highly resistant microorganisms acquired in intensive-care units... - Detection of carbapenemase-producing Enterobacteriaceae with a commercial DNA microarrayJames Cohen Stuart
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
J Med Microbiol 61:809-12. 2012..In conclusion, the CDT102 microarray is a rapid and accurate tool for the detection of carbapenemase and ESBL genes, although the array seems less suitable for epidemiology of ESBL genes... - A set of multiplex PCRs for genotypic detection of extended-spectrum β-lactamases, carbapenemases, plasmid-mediated AmpC β-lactamases and OXA β-lactamasesGuido M Voets
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
Int J Antimicrob Agents 37:356-9. 2011.... - Guideline for phenotypic screening and confirmation of carbapenemases in EnterobacteriaceaeJames Cohen Stuart
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
Int J Antimicrob Agents 36:205-10. 2010.... - Evolution in quantum leaps: multiple combinatorial transfers of HPI and other genetic modules in EnterobacteriaceaeArmand Paauw
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
PLoS ONE 5:e8662. 2010..Multiple combinatorial transfers of diverse combinations of the HPI and other genomic elements among Enterobacteriaceae may accelerate the generation of new pathogenic strains... - Evaluation of a commercial microarray as a confirmation test for the presence of extended-spectrum β-lactamases in isolates from the routine clinical settingT N Platteel
SALTRO, Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Microbiol Infect 17:1435-8. 2011..Using sequencing as the reference method the sensitivity of the microarray was 97% (237/245), the specificity 98% (97/99), the positive predictive value 99% (237/239) and the negative predictive value 92% (97/105)... - Changes in heart rate, mean arterial pressure, and oxygen saturation after open and closed endotracheal suctioning: a prospective observational studyIrene P Jongerden
Department of Intensive Care Medicine, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
J Crit Care 27:647-54. 2012..We, therefore, quantified changes in heart rate (HR), mean arterial pressure (MAP), and peripheral oxygen saturation (Spo(2)) in patients undergoing endotracheal suctioning (ES) with CSS and OSS... - Genomic diversity within the Enterobacter cloacae complexArmand Paauw
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
PLoS ONE 3:e3018. 2008..Identification of species based on currently available genotyping tools is already superior to phenotypic identification, but the taxonomy of isolates belonging to this complex is cumbersome... - A bundle approach to reduce the incidence of external ventricular and lumbar drain-related infectionsMaurine A Leverstein-van Hall
Department of Microbiology, Infectious Diseases and Inflammation, and Hospital Hygiene and Infection Prevention, Utrecht, The Netherlands
J Neurosurg 112:345-53. 2010..In 2003, a high rate (37%) of probable drain-related infections was identified at the authors' hospital. A multidisciplinary working group was installed to reduce this incidence to < 10% within 1.5 years... - Colistin resistance in gram-negative bacteria during prophylactic topical colistin use in intensive care unitsEvelien A N Oostdijk
Department of Medical Microbiology, University Medical Center Utrecht, G04 614, PO Box 85500, 3508 GA, Utrecht, The Netherlands
Intensive Care Med 39:653-60. 2013..We quantified effects of selective decontamination on acquisition of colistin-resistant gram-negative bacteria (GNB) using data from a cluster-randomized study and a single-centre cohort... - [Identical resistance genes and plasmids in Escherichia coli from Dutch patients, poultry and retail chicken meat]Maurine A Leverstein-van Hall
Universitair Medisch Centrum, Utrecht, Afd Medische Microbiologie, The Netherlands
Ned Tijdschr Geneeskd 155:A3401. 2011..coli isolates from patients in the Netherlands... - Detection of Candida spp. in blood cultures using nucleic acid sequence-based amplification (NASBA)A Borst
Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, University Medical Center, Utrecht, The Netherlands
Diagn Microbiol Infect Dis 39:155-60. 2001..In summary, using NASBA for the detection of yeast RNA in blood cultures, we have shown for the first time that it is possible to improve the detection rate of yeasts in blood cultures by using amplification technology... - Yersiniabactin reduces the respiratory oxidative stress response of innate immune cellsArmand Paauw
Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
PLoS ONE 4:e8240. 2009.... - Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in childrenErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
J Antimicrob Chemother 63:1011-6. 2009..The aim of this study was to test the hypothesis that trimethoprim/sulfamethoxazole selects for integron-positive and multidrug-resistant Enterobacteriaceae in the intestinal flora... - Influence of sampling technique on detection of potential pathogens in the nasopharynxErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:752-5. 2006..To determine the optimal approach for nasopharyngeal culture and to establish which approach children tolerate best... - Ecological effects of selective decontamination on resistant gram-negative bacterial colonizationEvelien A N Oostdijk
Department of Medical Microbiology, University Medical Center Utrecht, GA Utrecht, The Netherlands
Am J Respir Crit Care Med 181:452-7. 2010.... - Effect of open and closed endotracheal suctioning on cross-transmission with Gram-negative bacteria: a prospective crossover studyIrene P Jongerden
Department of Vital Functions, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 39:1313-21. 2011..The objective was to determine whether closed suction systems, as compared with open suction systems, reduce the incidence of cross-transmission of Gram-negative bacteria in intensive care units... - Decontamination of the digestive tract and oropharynx in ICU patientsA M G A de Smet
Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
N Engl J Med 360:20-31. 2009....