Research Topics
| Robert LandeweSummaryAffiliation: University Hospital Maastricht Country: The Netherlands Publications
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Detail Information
Publications
Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritisDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands
Arthritis Res Ther 9:R62. 2007..The change in size of erosion was also picked up by independent readers applying the van der Heijde-modified Sharp scoring method and was reflected in their scores...
COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief interventionRobert B M Landewe
Department of Internal Medicine Rheumatology, PO Box 5800, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 46:347-56. 2002..The current study was conducted to investigate whether the benefits of COBRA therapy were sustained over time, and to determine which baseline factors could predict outcome...- Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritisRobert Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 50:1390-9. 2004.... - Disconnect between inflammation and joint destruction after treatment with etanercept plus methotrexate: results from the trial of etanercept and methotrexate with radiographic and patient outcomesRobert Landewe
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 54:3119-25. 2006.... - Arthritis instantaneously causes collagen type I and type II degradation in patients with early rheumatoid arthritis: a longitudinal analysisR B M Landewé
Department of Internal Medicine Rheumatology, University Hospital Maastricht, Netherlands
Ann Rheum Dis 65:40-4. 2006..Markers of collagen type I (CTX-1) and type II (CTX-II) degradation, reflecting bone and cartilage breakdown, appear to predict long term radiographic progression in chronic persistent arthritis... - Scoring sacroiliac joints by magnetic resonance imaging. A multiple-reader reliability experimentRobert B M Landewe
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, University Maastricht, 6202 AZ Maastricht, The Netherlands
J Rheumatol 32:2050-5. 2005.... 
Physical function in ankylosing spondylitis is independently determined by both disease activity and radiographic damage of the spineR Landewe
Department of Internal Medicine, Maastricht University Medical Centre, The Netherlands
Ann Rheum Dis 68:863-7. 2009..Univariate correlations were calculated on baseline values using the Spearman rank correlation. Multivariate associations were investigated by generalised estimating equations (GEE) on baseline and 2-year data...- Presentation and analysis of radiographic data in clinical trials and observational studiesR Landewe
University Hospital Maastricht, Department of Internal Medicine Rheumatology, PO Box 5800, 6202AZ Maastricht, The Netherlands
Ann Rheum Dis 64:iv48-51. 2005.... - Radiographic progression in rheumatoid arthritisRobert Landewe
University Hospital Maastricht, Department Internal Medicine Rheumatology, P O Box 5800, 6202AZ Maastricht, The Netherlands
Clin Exp Rheumatol 23:S63-8. 2005.... - The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28Robert Landewe
University Hospital Maastricht, Department of Internal Medicine Rheumatology, Maastricht, The Netherlands
Arthritis Res Ther 8:107. 2006..This commentary elaborates on how such a measure of severity should be validated to determine whether it is appropriate for practical use... - Which patients with ankylosing spondylitis should be treated with tumour necrosis factor inhibiting therapy? A survey among Dutch rheumatologistsR Landewe
University Hospital Maastricht, Department of Internal Medicine Rheumatology, Maastricht, Netherlands
Ann Rheum Dis 63:530-4. 2004..To determine the criteria considered important by Dutch rheumatologists in judging whether a patient with ankylosing spondylitis should start tumour necrosis factor (TNF) blocking therapy... - Primer: challenges in randomized and observational studiesRobert Landewe
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Nat Clin Pract Rheumatol 3:661-6. 2007..This Review compares RCTs and observational studies with regard to particular limitations, and explains how the credibility of results from observational studies can be improved by making use of advanced analytical techniques... - Follow up studies in rheumatoid arthritisR Landewe
University Hospital, Department of Internal Medicine Rheumatology, Maastricht, The Netherlands
Ann Rheum Dis 61:479-81. 2002 - Twenty-eight-joint counts invalidate the DAS28 remission definition owing to the omission of the lower extremity joints: a comparison with the original DAS remissionR Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, Netherlands
Ann Rheum Dis 65:637-41. 2006..To compare 28 joint disease activity score (DAS28) remission with comprehensive joint count DAS remission in rheumatoid arthritis... - Principles of assessment from a clinical perspectiveRobert B M Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, P O Box 5800, 6202 AZ Maastricht, The Netherlands
Best Pract Res Clin Rheumatol 17:365-79. 2003..The former perspective incorporates test-specific characteristics, such as sensitivity, specificity, accuracy and cut-off levels, and the latter deals with individual probabilities from a 'Bayesian' concept... - Early rheumatoid arthritis: toward tailor-made therapyRobert B M Landewe
Department of Internal Medicine and Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Curr Rheumatol Rep 5:287-93. 2003.... - Is radiographic progression a realistic outcome measure in clinical trials with early inflammatory arthritis?R Landewe
Department Internal Medicine Rheumatology, University Hospital, P O Box 5800, 6202 AZ Maastricht, The Netherlands
Clin Exp Rheumatol 21:S37-41. 2003..We propose here a number of recommendations for the use of radiographic progression as one of the obligatory outcome measures in clinical trials with EIA... - Presentation and analysis of data on radiographic outcome in clinical trials: experience from the TEMPO studyDesiree van der Heijde
Rheumatology Department, University Hospital, Maastricht, The Netherlands
Arthritis Rheum 52:49-60. 2005..To evaluate different methods of presentation and analysis of radiographic data in a rheumatoid arthritis (RA) randomized controlled trial... - High or low intensity aerobic fitness training in fibromyalgia: does it matter?Marijke van Santen
Department of Internal Medicine, University Hospital, Maastricht, The Netherlands
J Rheumatol 29:582-7. 2002..To determine the efficacy of training in fibromyalgia (FM), we compared the effects of high intensity fitness training (HIF) and low intensity fitness training (LIF)... - Is there a preferred method for scoring activity of the spine by magnetic resonance imaging in ankylosing spondylitis?Desiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht and CAPHRI Research Institute, University Maastricht, The Netherlands d vanderheijde kpnplanet nl
J Rheumatol 34:871-3. 2007..The Berlin and SPARCC methods were preferred most frequently. The development of a new method combining the best elements of all methods is an additional possibility... - Automated measurement of joint space width in small joints of patients with rheumatoid arthritisCédric Lukas
University of Maastricht, Maastricht, The Netherlands
J Rheumatol 35:1288-93. 2008..Comparison of performances of 5 (semi)automated methods in measuring joint space width (JSW) in rheumatoid arthritis... - Scoring inflammatory activity of the spine by magnetic resonance imaging in ankylosing spondylitis: a multireader experimentCédric Lukas
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, The Netherlands
J Rheumatol 34:862-70. 2007..We investigated feasibility, inter-reader reliability, sensitivity to change, and discriminatory ability of 3 different scoring methods for MRI activity and change in activity of the spine in patients with AS... - How do the EQ-5D, SF-6D and the well-being rating scale compare in patients with ankylosing spondylitis?Annelies Boonen
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Ann Rheum Dis 66:771-7. 2007..Purpose: To compare aspects of validity of EuroQol-5 Dimensions (EQ-5D) and Short-Form-6 Dimensions (SF-6D), two indirect utility instruments, and the well-being rating scale (RS) in ankylosing spondylitis (AS)... - How should treatment effect on spinal radiographic progression in patients with ankylosing spondylitis be measured?Desiree van der Heijde
University Hospital Maastricht and CAPHRI Research Institute, Maastricht, The Netherlands
Arthritis Rheum 52:1979-85. 2005 - Measurement of spinal mobility in ankylosing spondylitis: comparison of occiput-to-wall and tragus-to-wall distanceLiesbeth Heuft-Dorenbosch
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 31:1779-84. 2004..To investigate if the tragus-to-wall distance (TWD) is more reliable compared to the occiput-to-wall distance (OWD) as a measurement for thoracic spine extension in patients with ankylosing spondylitis (AS)... - Are syndesmophytes most prevalent in the lumbar or in the cervical spine in patients with ankylosing spondylitis and do they develop in a specific direction?Astrid van Tubergen
Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Rheumatology (Oxford) 51:1432-9. 2012..To describe the distribution of prevalent syndesmophytes and bridges, and the occurrence of new ones in a prevalence cohort of patients with AS... - The influence of peripheral arthritis on disease activity in ankylosing spondylitis patients as measured with the Bath Ankylosing Spondylitis Disease Activity IndexLiesbeth Heuft-Dorenbosch
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 51:154-9. 2004..To investigate whether scores on the BASDAI change by omitting the 2 questions on peripheral disease... - Cost effectiveness of combined spa-exercise therapy in ankylosing spondylitis: a randomized controlled trialAstrid van Tubergen
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:459-67. 2002.... - Development of new syndesmophytes and bridges in ankylosing spondylitis and their predictors: a longitudinal studyAstrid van Tubergen
Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, The Netherlands
Ann Rheum Dis 71:518-23. 2012..Structural damage of the spine in ankylosing spondylitis (AS) is associated with worse physical function and impaired spinal mobility. Knowledge about predictors of new syndesmophyte formation is limited... - Magnetic resonance imaging changes of sacroiliac joints in patients with recent-onset inflammatory back pain: inter-reader reliability and prevalence of abnormalitiesLiesbeth Heuft-Dorenbosch
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, The Netherlands
Arthritis Res Ther 8:R11. 2006..About one-third of patients with recent-onset inflammatory back pain show inflammation, and about one-sixth show structural changes in at least one SI joint... - Assessment of fatigue in patients with ankylosing spondylitis: a psychometric analysisAstrid van Tubergen
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:8-16. 2002.... - Repair in rheumatoid arthritis, current status. Report of a workshop at OMERACT 8Desiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, and CAPHRI Research Institute, University Maastricht, The Netherlands
J Rheumatol 34:884-8. 2007..e., not limited to sum scores of all joints together. The conclusions of the workshop mean a big step forward in the acceptance and assessment of repair... - Selection of a method for scoring radiographs for ankylosing spondylitis clinical trials, by the Assessment in Ankylosing Spondylitis Working Group and OMERACTDesiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, University Maastricht, 6202 AZ Maastricht, The Netherlands
J Rheumatol 32:2048-9. 2005..Finally, both the ASAS Working Group and OMERACT participants voted for the modified Stoke AS Spinal Score (mSASSS) as the preferred scoring method for use in clinical trials in AS... - Radiographic progression depicted by probability plots: presenting data with optimal use of individual valuesRobert Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht and Research Institute Caphri, University of Maastricht, Maastricht, The Netherlands
Arthritis Rheum 50:699-706. 2004 - Predictive markers in rapidly progressing rheumatoid arthritisRobert Landewe
Department of Internal Medicine Division of Rheumatology and Caphri Research Institute, University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol Suppl 80:8-15. 2007..The search for predictive markers of arthritis outcome has been and undoubtedly will continue to be the subject of many studies. This article will review both established and emerging predictive markers in RA... - Imaging in spondylitisDesiree van der Heijde
University Hospital Maastricht and CAPHRI Research Institute, Maastricht, The Netherlands
Curr Opin Rheumatol 17:413-7. 2005..The purpose of this review is to describe and evaluate recent findings with respect to imaging in ankylosing spondylitis. The review includes articles from the literature that were published in 2004... - The feasibility and efficacy of a multidisciplinary intervention with aftercare meetings for fibromyalgiaMariëlle Kroese
Department of Integrated Care, University Hospital Maastricht, PO Box 5800, Maastricht 6202 AZ, The Netherlands
Clin Rheumatol 28:923-9. 2009..Our 12-week multidisciplinary part-time daycare intervention with five aftercare meetings for FM patients is feasible and it is indicated that it can lead to sustained improvement in functional status and quality of life... - Multiple computer-based methods of measuring joint space width can discriminate between treatment arms in the COBRA trial -- Update of an ongoing OMERACT projectJohn T Sharp
Maastricht University Medical Center, Department of Internal Medicine, Subdivision of Rheumatology, Maastricht, The Netherlands
J Rheumatol 36:1825-8. 2009..98 or 0.99 for 4 programs. The smallest detectable change was < 0.2 mm for 4 of the 5 programs, representing 29%-36% of the change within the 99th percentile of measurements... - Use of a numerical rating scale as an answer modality in ankylosing spondylitis-specific questionnairesAstrid van Tubergen
Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:242-8. 2002..To assess the reproducibility and responsiveness of the instruments with the original scale and NRS... - Challenges in demonstrating the effectiveness of multidisciplinary treatment on quality of life, participation and health care utilisation in patients with fibromyalgia: a randomised controlled trialYvonne van Eijk-Hustings
Department of Integrated Care, Maastricht University Medical Centre, P O Box 5800, 6202 AZ Maastricht, The Netherlands
Clin Rheumatol 32:199-209. 2013..MD seemed to yield positive effects, but firm conclusions with regard to effectiveness cannot be formulated due to small between-group differences and limitations of the study... - Impact of ankylosing spondylitis on sick leave, presenteeism and unpaid productivity, and estimation of the societal costAnnelies Boonen
Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, P Debyelaan 25, Maastricht 6229HX, The Netherlands
Ann Rheum Dis 69:1123-8. 2010..To describe the influence of ankylosing apondylitis (AS) on sick leave, presenteeism and unpaid work restrictions and to estimate related productivity costs... - EULAR recommendations for the role of the nurse in the management of chronic inflammatory arthritisYvonne van Eijk-Hustings
Department of Integrated Care, Maastricht University Medical Centre, Postbox 5800, 6202 AZ Maastricht, The Netherlands
Ann Rheum Dis 71:13-9. 2012..The authors aim to develop European League Against Rheumatism recommendations for the role of the nurse in the management of patients with chronic inflammatory arthritis, to identify a research agenda and to determine an educational agenda... - A randomized clinical trial comparing fitness and biofeedback training versus basic treatment in patients with fibromyalgiaMarijke van Santen
Department of Internal Medicine, University Hospital Maastricht, The Netherlands
J Rheumatol 29:575-81. 2002..To compare the therapeutic effects of physical fitness training or biofeedback training with the results of usual care in patients with fibromyalgia (FM)...