W Korver

Summary

Affiliation: University Medical Center
Country: The Netherlands

Publications

  1. pmc The winged-helix transcription factor Trident is expressed in cycling cells
    W Korver
    Department of Immunology, University Hospital Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Nucleic Acids Res 25:1715-9. 1997
  2. ncbi request reprint The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization
    W Korver
    Department of Immunology, University Hospital Utrecht, The Netherlands
    Genomics 46:435-42. 1997
  3. ncbi request reprint The winged-helix transcription factor Trident is expressed in actively dividing lymphocytes
    W Korver
    Department of Immunology, University Hospital Utrecht, The Netherlands
    Immunobiology 198:157-61. 1997
  4. ncbi request reprint The Sox-13 gene: structure, promoter characterization, and chromosomal localization
    J Roose
    Department of Immunology, University Hospital Utrecht, Utrecht, 3508 GA, The Netherlands
    Genomics 57:301-5. 1999
  5. pmc High expression of the HMG box factor sox-13 in arterial walls during embryonic development
    J Roose
    Department of Immunology, University Hospital, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Nucleic Acids Res 26:469-76. 1998
  6. ncbi request reprint Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident
    W Korver
    Department of Immunology University Hospital Utrecht P O Box 85500 3508 GA Utrecht The Netherlands DNAX Research Institute 901 California Avenue Palo Alto California 94304 USA
    Curr Biol 8:1327-30. 1998
  7. ncbi request reprint The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
    A O Walter
    DNAX Research Institute, Palo Alto, California 94304, USA
    Oncogene 19:4906-16. 2000

Collaborators

Detail Information

Publications7

  1. pmc The winged-helix transcription factor Trident is expressed in cycling cells
    W Korver
    Department of Immunology, University Hospital Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Nucleic Acids Res 25:1715-9. 1997
    ..PCR-mediated selection of optimal binding sites yielded a consensus motif resembling that of other family members. These results identify Trident as a transcription factor, which is likely involved in cell cycle-specific gene regulation...
  2. ncbi request reprint The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization
    W Korver
    Department of Immunology, University Hospital Utrecht, The Netherlands
    Genomics 46:435-42. 1997
    ..The winged-helix DNA-binding domain is encoded on three exons. Analysis of the promoter in synchronized Rat-1 fibroblasts revealed a fragment of 300 bases responsible for the cell cycle-specific expression of the TRIDENT gene...
  3. ncbi request reprint The winged-helix transcription factor Trident is expressed in actively dividing lymphocytes
    W Korver
    Department of Immunology, University Hospital Utrecht, The Netherlands
    Immunobiology 198:157-61. 1997
    ..In peripheral blood lymphocytes, expression of Trident mRNA was absent, but could be induced upon stimulation with mitogens in vitro. These observations imply a function for Trident in dividing lymphocytes...
  4. ncbi request reprint The Sox-13 gene: structure, promoter characterization, and chromosomal localization
    J Roose
    Department of Immunology, University Hospital Utrecht, Utrecht, 3508 GA, The Netherlands
    Genomics 57:301-5. 1999
    ..To determine the chromosomal localization of the human gene, a human SOX13 cDNA was isolated with 75% homology to the mouse Sox-13. FISH analysis mapped the human SOX13 gene to chromosome 1 band q32...
  5. pmc High expression of the HMG box factor sox-13 in arterial walls during embryonic development
    J Roose
    Department of Immunology, University Hospital, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Nucleic Acids Res 26:469-76. 1998
    ..The Sox-13 protein binds to the consensus HMG box motif, AACAAAG, but does not transactivate transcription through a concatamer of this motif. Sox-13, like other members of the Sox family likely plays an important role in development...
  6. ncbi request reprint Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident
    W Korver
    Department of Immunology University Hospital Utrecht P O Box 85500 3508 GA Utrecht The Netherlands DNAX Research Institute 901 California Avenue Palo Alto California 94304 USA
    Curr Biol 8:1327-30. 1998
    ..Our results indicate that expression of Trident is required to prevent multiple rounds of S phase in the heart and the liver. Trident therefore appears to have a role in preventing DNA re-replication during the G2 and M phases...
  7. ncbi request reprint The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
    A O Walter
    DNAX Research Institute, Palo Alto, California 94304, USA
    Oncogene 19:4906-16. 2000
    ..Our experiments suggest that phosphorylation of T288 is important for regulation of the Aurora2 kinase both for its activity and its stability...