Detail Information
Publications
A systematic review of analytical methods used to study subgroups in (individual patient data) meta-analysesLaura Koopman
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
J Clin Epidemiol 60:1002-9. 2007..To determine whether individual patient data meta-analyses (IPDMA) are used to perform subgroup analyses and to study whether the analytical methods regarding subgroup analyses differ between IPDMA and conventional meta-analyses (CMA)...
Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis mediaLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Epidemiol 167:540-5. 2008..In the authors' empirical example, imputation within trials appears to be the most appropriate approach of handling missing data in individual patient data meta-analyses...
Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient dataLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 134:128-32. 2008..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children...
Empirical comparison of subgroup effects in conventional and individual patient data meta-analysesLaura Koopman
University Medical Center Utrecht, Utrecht, The Netherlands
Int J Technol Assess Health Care 24:358-61. 2008..Our objective is to compare such subgroup effects using the data of six trials (n = 1,643) on the effectiveness of antibiotics in children with acute otitis media (AOM)...
