Research Topics
| Merel KindtSummaryAffiliation: University of Amsterdam Country: The Netherlands Publications
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Detail Information
Publications
Peritraumatic dissociation and posttraumatic stress after pregnancy loss: a prospective studyIris M Engelhard
Department of Medical, Clinical and Experimental Psychology, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
Behav Res Ther 41:67-78. 2003..It also predicted chronic PTSD symptoms, and this relation was mediated by acute PTSD symptoms...- Treatment of PTSD: a comparison of imaginal exposure with and without imagery rescriptingArnoud Arntz
Department of Clinical Psychological Science, University of Maastricht, PO Box 616, NL 6200 MD Maastricht, The Netherlands
J Behav Ther Exp Psychiatry 38:345-70. 2007..Results suggest that the addition of rescripting to IE makes the treatment more acceptable for both patients and therapists, and leads to better effects on non-fear problems like anger and guilt... 
Dissociating response systems: erasing fear from memoryMarieke Soeter
Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Neurobiol Learn Mem 94:30-41. 2010..From a clinical and ethical perspective, disrupting reconsolidation points to promising interventions persistently erasing fear responses from trauma memory without affecting the actual recollection...- Reconsolidation in a human fear conditioning study: a test of extinction as updating mechanismMerel Kindt
Department of Clinical Psychology, Faculty of Social and Behavioural Sciences, University of Amsterdam, Weesperplein 4, 1018 XA Amsterdam, The Netherlands
Biol Psychol 92:43-50. 2013..These conflicting results ask for further critical testing given the potential impact on the field of emotional memory and its application to clinical practice... - Dissociation related to subjective memory fragmentation and intrusions but not to objective memory disturbancesMerel Kindt
Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
J Behav Ther Exp Psychiatry 36:43-59. 2005.... - Beyond extinction: erasing human fear responses and preventing the return of fearMerel Kindt
Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Nat Neurosci 12:256-8. 2009..Disrupting the reconsolidation of fear memory opens up new avenues for providing a long-term cure for patients with emotional disorders... - Perceptual and conceptual processing as predictors of treatment outcome in PTSDMerel Kindt
Department of Clinical Psychology, Faculty of Social and Behavioural Sciences, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
J Behav Ther Exp Psychiatry 38:491-506. 2007..The results suggest that imaginal reliving during CBT is not crucial for symptom reduction, but it may promote conceptual processing, which in itself predicts a better treatment outcome... - The influence of data-driven versus conceptually-driven processing on the development of PTSD-like symptomsMerel Kindt
Faculty of Social and Behavioural Sciences, Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
J Behav Ther Exp Psychiatry 39:546-57. 2008..The data support the viability of the distinction between data-driven/conceptually-driven processing for the understanding of the development of PTSD... - Interpretation bias for heart sensations in congenital heart disease and its relation to quality of lifePetra A Karsdorp
Department of Psychology, University of Amsterdam, The Netherlands
Int J Behav Med 15:232-40. 2008..Previous studies have shown that patients with congenital heart disease (ConHD) report a diminished health-related quality of life... 
Stimulation of the noradrenergic system during memory formation impairs extinction learning but not the disruption of reconsolidationMarieke Soeter
Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands
Neuropsychopharmacology 37:1204-15. 2012..Given that the noradrenergic strengthening of fear memory impaired extinction learning but not the disruption of reconsolidation, our findings may have implications for the treatment of anxiety disorders...- False heart rate feedback and the perception of heart symptoms in patients with congenital heart disease and anxietyPetra A Karsdorp
Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
Int J Behav Med 16:81-8. 2009..In the present study, it was suggested that a combination of high trait anxiety and disease history increases the perception of heart symptoms... - Instructed extinction differentially affects the emotional and cognitive expression of associative fear memoryDieuwke Sevenster
Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands
Psychophysiology 49:1426-35. 2012..Although the manipulation facilitated extinction learning, it did not prevent the recovery of the startle response. The present findings are better explained by a dual- rather than a single-process account of fear learning... - Noradrenergic enhancement of associative fear memory in humansMarieke Soeter
Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Neurobiol Learn Mem 96:263-71. 2011..The present findings suggest that noradrenaline may play an important role in the etiology and maintenance of anxiety disorders... - Disrupting reconsolidation: pharmacological and behavioral manipulationsMarieke Soeter
Department of Clinical Psychology, University of Amsterdam, 1018 WB Amsterdam, The Netherlands
Learn Mem 18:357-66. 2011..Our findings demonstrate that disrupting reconsolidation by pharmacological manipulations, although selective, undermines the generalization of fear, a key feature of anxiety disorders... - Fear generalization in humans: impact of verbal instructionsBram Vervliet
University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Behav Res Ther 48:38-43. 2010..Hence, the same learning experience can have opposite effects in terms of fear generalization, depending on verbally transmitted information about the relative importance of individual stimulus features... - Preattentive processing of heart cues and the perception of heart symptoms in congenital heart diseasePetra A Karsdorp
Department of Psychology, Faculty of Social and Behavioural Sciences, University of Amsterdam, Roetersstraat 15, Amsterdam, The Netherlands
Behav Res Ther 45:1893-902. 2007..Preattentive processing of harmless heart cues may easily elicit overperception of heart symptoms in highly trait anxious patients with ConHD... - Neural substrates of individual differences in human fear learning: evidence from concurrent fMRI, fear-potentiated startle, and US-expectancy dataSonja van Well
University of Amsterdam, Amsterdam, The Netherlands
Cogn Affect Behav Neurosci 12:499-512. 2012..Our study provides the first evidence for the potential of examining startle potentiation in concurrent fMRI research on fear learning... - Retrieval per se is not sufficient to trigger reconsolidation of human fear memoryDieuwke Sevenster
Department of Clinical Psychology, University of Amsterdam, Weesperplein 4, 1018 XA Amsterdam, The Netherlands
Neurobiol Learn Mem 97:338-45. 2012..Second, mere retrieval of the fear memory is not sufficient to induce its labilization and reconsolidation... - Fear generalization in humans: Impact of prior non-fearful experiencesBram Vervliet
Department of Clinical Psychology, University of Amsterdam, The Netherlands
Behav Res Ther 48:1078-84. 2010..The results show significantly less generalization in this group, suggesting that prior non-fearful experiences can protect against fear generalization. These results may inspire novel ways to prevent the development of clinical anxiety... - Erasing fear for an imagined threat eventMarieke Soeter
Department of Clinical Psychology, University of Amsterdam, Weesperplein 4, 1018 XA Amsterdam, The Netherlands
Psychoneuroendocrinology 37:1769-79. 2012.... - The effects of noradrenergic blockade on extinction in humansMarieke G N Bos
Department of Clinical Psychology, University of Amsterdam, The Netherlands
Biol Psychol 89:598-605. 2012..These findings indicate that careful selection of timing parameters is essential to ensure that pharmacological agents interfere with the intended memory process to reduce fear... - Psychological and cognitive functioning in children and adolescents with congenital heart disease: a meta-analysisPetra A Karsdorp
University of Amsterdam, The Netherlands
J Pediatr Psychol 32:527-41. 2007..The aim of the present study was to systematically review this empirical body of literature... - Trained interpretive bias and anxietyElske Salemink
Department of Clinical Psychology, Utrecht University, P O Box 80140, 3508 TC Utrecht, The Netherlands
Behav Res Ther 45:329-40. 2007..Effects of trained interpretive bias on anxiety were only marginal and absent on anxiety vulnerability. It appears that interpretive bias can be trained reliably, but its effects on mood and vulnerability require further explanation... - Prediction error governs pharmacologically induced amnesia for learned fearDieuwke Sevenster
Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands
Science 339:830-3. 2013..Insight into the process of memory updating is crucial for understanding the optimal and boundary conditions on reconsolidation and provides a clear guide for the development of reconsolidation-based treatments... - Worrying affects associative fear learning: a startle fear conditioning studyFemke J Gazendam
Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands
PLoS ONE 7:e34882. 2012..The implication of our findings is that they show how worry may contribute to the development of anxiety disorders by affecting associative fear learning... - Salivary alpha amylase and cortisol responses to different stress tasks: impact of sexAnda H van Stegeren
University of Amsterdam, Department of Clinical Psychology and Cognitive Science Center Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Int J Psychophysiol 69:33-40. 2008..Men had higher sAA levels than women during the complete course of the study, but men and women were comparable in their responsivity to the tasks. No strong correlations between sAA and CORT responses were found... - Contextual control of human fear associations in a renewal paradigmMarieke Effting
Department of Clinical Psychology, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Behav Res Ther 45:2002-18. 2007..In contrast to the model, the findings suggest that in humans not only extinction learning, but also fear acquisition is controlled by its current context... - Trauma processing and the development of posttraumatic stress disorderMerel Kindt
Department of Clinical Psychology, University of Amsterdam, Faculty of Social and Behavioural Sciences, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands. m
J Behav Ther Exp Psychiatry 36:69-76. 2005 - Compulsive perseveration: empirical criticism on the mood-as-input modelMarcel van den Hout
Department of Clinical Psychology, Utrecht University, The Netherlands
Behav Res Ther 45:1221-30. 2007..The findings raise questions about the validity of the paradigm as a model of OC perseveration... - Effects of positive interpretive bias modification in highly anxious individualsElske Salemink
Department of Clinical and Health Psychology, Utrecht University, PO Box 80140, 3508 TC Utrecht, The Netherlands
J Anxiety Disord 23:676-83. 2009..No effects were observed on social anxiety and stress vulnerability. The mixed pattern of findings renders them rather inconclusive, leaving interpretations of the potential therapeutic merits of CBM-I open for future research... - How does Cognitive Bias Modification affect anxiety? Mediation analyses and experimental dataElske Salemink
Utrecht University, The Netherlands
Behav Cogn Psychother 38:59-66. 2010..A crucial assumption is that the effect of the procedure on anxiety is mediated by change in interpretive bias rather than being a direct effect of the procedure. Surprisingly, this had not previously been tested... - Blocking mineralocorticoid receptors prior to retrieval reduces contextual fear memory in miceMing Zhou
Center for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands
PLoS ONE 6:e26220. 2011..We tested here whether blockade of MRs or GRs during retrieval also affects subsequent expression of fear memory... - Interacting noradrenergic and corticosteroid systems shift human brain activation patterns during encodingAnda H van Stegeren
University of Amsterdam, Department of Clinical Psychology, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Neurobiol Learn Mem 93:56-65. 2010.... - Stress-induced heart symptoms and perceptual biases in patients with congenital heart diseasePetra A Karsdorp
Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
Int J Cardiol 114:352-7. 2007..The present study tested the hypothesis that the combination of ConHD and high trait anxiety increases the perception of heart symptoms during acute stress... - Associative learning increases trial-by-trial similarity of BOLD-MRI patternsRenee M Visser
Department of Clinical Psychology, University of Amsterdam, 1018 WB Amsterdam, The Netherlands
J Neurosci 31:12021-8. 2011..We conclude that trial-by-trial MVPA is a useful tool for examining how the human brain encodes relevant associations and forms new associative networks... - Neural pattern similarity predicts long-term fear memoryRenee M Visser
Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands
Nat Neurosci 16:388-90. 2013..We found that the long-term behavioral expression of fear memory could be predicted from neural patterns at the time of learning... - Psychophysiological response patterns to affective film stimuliMarieke G N Bos
Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands Cognitive Science Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands
PLoS ONE 8:e62661. 2013..We discuss the important value of ASR in psychophysiological research on emotion and speculate on HRV as a potential biological marker for demarcating adaptive from maladaptive responding... - What's wrong with fear conditioning?Tom Beckers
University of Amsterdam, Department of Clinical Psychology, Weesperplein 4, 1018 XA Amsterdam, The Netherlands
Biol Psychol 92:90-6. 2013..We present preliminary data that illustrate these ideas and discuss the importance of response systems divergence in understanding individual differences in vulnerability for the development of pathological anxiety... - Deficient safety learning characterizes high trait anxious individualsFemke J Gazendam
Department of Clinical Psychology, University of Amsterdam, Weesperplein 4, 1018 XA Amsterdam, The Netherlands Electronic address
Biol Psychol 92:342-52. 2013..We conclude that high trait anxiety may be characterized by deficient safety learning which in turn may promote persistent and generalized fear responses... - Selective attention and threat: quick orienting versus slow disengagement and two versions of the dot probe taskElske Salemink
Clinical Psychology, Faculty of Social and Behavioural Sciences, Utrecht University, P O Box 80140, 3508 TC Utrecht, The Netherlands
Behav Res Ther 45:607-15. 2007..Concerning the relative merits of the two dot probe task versions, the results suggest that the detection task may be superior to the differentiation task. Implications for past and future research are discussed... - Dissociation and memory fragmentation: experimental effects on meta-memory but not on actual memory performanceMerel Kindt
Department of Medical, Clinical and Experimental Psychology, Maastricht University, 6200 MD, Maastricht, The Netherlands
Behav Res Ther 41:167-78. 2003..The present findings suggest that the claim that dissociation induces memory fragmentation may have to be confined to meta-memory. Implications of this divergence between actual memory and meta-memory are discussed... - Phenomenological validity of an OCD-memory model and the remember/know distinctionMarcel van den Hout
Maastricht University, Postbus 616, 6200 MD Maastricht, The Netherlands
Behav Res Ther 41:369-78. 2003..The latter does not reduce distrust but rather increases distrust and the patient may get trapped in a spiral of mutually reinforcing checking behavior and memory distrust... - Emotional reasoning and parent-based reasoning in normal childrenMattijn Morren
Department of Medical, Clinical and Experimental Psychology, Maastricht University, The Netherlands
Child Psychiatry Hum Dev 35:3-20. 2004..High levels of anxiety and depression were significantly associated with the tendency to rely on anxiety-response information, but only in the case of safety scripts... - Emotional memory is perceptualArnoud Arntz
Department of Medical, Clinical and Experimental Psychology, Maastricht University, P O Box 616, NL 6200 MD Maastricht, The Netherlands
J Behav Ther Exp Psychiatry 36:19-34. 2005..This might be related to the prominent position of perceptual memories in traumatic memory, manifest in intrusions, nightmares and reliving experiences... - Cognitive mechanisms and posttraumatic stress disorder: clinical and analogue researchIris M Engelhard
J Behav Ther Exp Psychiatry 36:1-2. 2005 - Instructed neutralization, spontaneous neutralization and prevented neutralization after an obsession-like thoughtMarcel van den Hout
Department of Medical, Clinical and Experimental Psychology, Maastricht University, PO Box 616, NL 6200 MD Maastricht, Netherlands
J Behav Ther Exp Psychiatry 33:177-89. 2002..Yet, contrary to expectation, this increase in anxiety did not discriminate the "neutralization prevention" group from the other two groups. Limitations of the paradigm as a model for clinical obsessions are discussed... - Repeated checking causes memory distrustMarcel van den Hout
Department of Medical, Clinical and Experimental Psychology, University of Maastricht, P O Box 616, 6200 MD Maastricht, Netherlands
Behav Res Ther 41:301-16. 2003..OCD checking may be motivated by the wish to reduce uncertainty, but checking appears to be a counter-productive safety strategy. Rather than reducing doubt, checking fosters doubt and ironically increases meta-memory problems... - Obsessive-compulsive disorder and the paradoxical effects of perseverative behaviour on experienced uncertaintyMarcel van den Hout
Utrecht University, Postbus 80140, 3508 TC Utrecht, The Netherlands
J Behav Ther Exp Psychiatry 35:165-81. 2004..The experimental preparation may be used as a model for OCD checking. The study suggests that repeated checking is sufficient to cause paradoxical effects on memory trust and that repeated checking is a counterproductive safety strategy... - Trained interpretive bias: validity and effects on anxietyElske Salemink
Department of Clinical and Health Psychology, Utrecht University, P O Box 80140, 3508 TC Utrecht, The Netherlands
J Behav Ther Exp Psychiatry 38:212-24. 2007..Moreover, evidence was found for effects of biased interpretations on anxiety. This demonstrates the viability of the present paradigm, which has implications for clinical practice...