C Kemner

Summary

Affiliation: University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Normal P50 gating in children with autism
    Chantal Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Clin Psychiatry 63:214-7. 2002
  2. doi request reprint Smooth pursuit eye movement (SPEM) in patients with multiple complex developmental disorder (MCDD), a subtype of the pervasive developmental disorder
    Bertine E Lahuis
    Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, and the Rudolph Magnus Institute of Neurosciences, The Netherlands
    World J Biol Psychiatry 10:905-12. 2009
  3. ncbi request reprint In search of neurophysiological markers of pervasive developmental disorders: smooth pursuit eye movements?
    C Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Neural Transm 111:1617-26. 2004
  4. ncbi request reprint Open-label study of olanzapine in children with pervasive developmental disorder
    Chantal Kemner
    University Medical Center Utrecht, Department of Child and Adolescent Psychiatry, The Netherlands
    J Clin Psychopharmacol 22:455-60. 2002
  5. ncbi request reprint Are abnormal event-related potentials specific to children with ADHD? A comparison with two clinical groups
    C Kemner
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht University, The Netherlands
    Percept Mot Skills 87:1083-90. 1998
  6. ncbi request reprint Perceptual and response interference in children with attention-deficit hyperactivity disorder, and the effects of methylphenidate
    L M Jonkman
    Faculty of Pharmacy, Department of Psychopharmacology, Rudolf Magnus Institute for Neurosciences, Utrecht University, The Netherlands
    Psychophysiology 36:419-29. 1999
  7. ncbi request reprint Attentional capacity, a probe ERP study: differences between children with attention-deficit hyperactivity disorder and normal control children and effects of methylphenidate
    L M Jonkman
    Faculty of Pharmacy, Department of Psychopharmacology, Utrecht University, The Netherlands
    Psychophysiology 37:334-46. 2000
  8. ncbi request reprint Differences in plasma concentrations of the D- and L-threo methylphenidate enantiomers in responding and non-responding children with attention-deficit hyperactivity disorder
    L M Jonkman
    Faculty of Social Sciences, Department of Psychonomics, Utrecht University, The Netherlands
    Psychiatry Res 78:115-8. 1998
  9. ncbi request reprint Eye movements, visual attention, and autism: a saccadic reaction time study using the gap and overlap paradigm
    J N van der Geest
    Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, The Netherlands
    Biol Psychiatry 50:614-9. 2001
  10. ncbi request reprint Effects of object complexity and type on the gaze behavior of children with pervasive developmental disorder
    C Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht and Rudolf Magnus Institute for Neurosciences, Utrecht University, Utrecht, The Netherlands
    Brain Cogn 65:107-11. 2007

Detail Information

Publications49

  1. ncbi request reprint Normal P50 gating in children with autism
    Chantal Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Clin Psychiatry 63:214-7. 2002
    ..For this reason, sensory filtering was measured in children with autism using the P50 gating paradigm...
  2. doi request reprint Smooth pursuit eye movement (SPEM) in patients with multiple complex developmental disorder (MCDD), a subtype of the pervasive developmental disorder
    Bertine E Lahuis
    Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, and the Rudolph Magnus Institute of Neurosciences, The Netherlands
    World J Biol Psychiatry 10:905-12. 2009
    ..The question was addressed whether patients with MCDD show the same psychophysiological abnormalities as seen in patients with schizophrenia...
  3. ncbi request reprint In search of neurophysiological markers of pervasive developmental disorders: smooth pursuit eye movements?
    C Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Neural Transm 111:1617-26. 2004
    ..Thus abnormalities in SPEM would appear not to be a marker of PDD. The earlier reported abnormalities in visual motion processing might need to be reinterpreted...
  4. ncbi request reprint Open-label study of olanzapine in children with pervasive developmental disorder
    Chantal Kemner
    University Medical Center Utrecht, Department of Child and Adolescent Psychiatry, The Netherlands
    J Clin Psychopharmacol 22:455-60. 2002
    ..Thus, while olanzapine was a relatively safe medication in children, its clinical relevance in children with pervasive developmental disorder may be limited...
  5. ncbi request reprint Are abnormal event-related potentials specific to children with ADHD? A comparison with two clinical groups
    C Kemner
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht University, The Netherlands
    Percept Mot Skills 87:1083-90. 1998
    ..It was concluded that a smaller amplitude of this peak is specific to children with ADHD...
  6. ncbi request reprint Perceptual and response interference in children with attention-deficit hyperactivity disorder, and the effects of methylphenidate
    L M Jonkman
    Faculty of Pharmacy, Department of Psychopharmacology, Rudolf Magnus Institute for Neurosciences, Utrecht University, The Netherlands
    Psychophysiology 36:419-29. 1999
    ..The conclusion that methylphenidate did not influence response processes contrasts sharply with findings reported by authors using the Sternberg memory search task...
  7. ncbi request reprint Attentional capacity, a probe ERP study: differences between children with attention-deficit hyperactivity disorder and normal control children and effects of methylphenidate
    L M Jonkman
    Faculty of Pharmacy, Department of Psychopharmacology, Utrecht University, The Netherlands
    Psychophysiology 37:334-46. 2000
    ..Furthermore, methylphenidate had enhancing effects on performance and ERPs, but did not improve the capacity-allocation deficit...
  8. ncbi request reprint Differences in plasma concentrations of the D- and L-threo methylphenidate enantiomers in responding and non-responding children with attention-deficit hyperactivity disorder
    L M Jonkman
    Faculty of Social Sciences, Department of Psychonomics, Utrecht University, The Netherlands
    Psychiatry Res 78:115-8. 1998
    ..Non-responders showed significantly higher plasma concentrations of both D- and L-threo MPH enantiomers...
  9. ncbi request reprint Eye movements, visual attention, and autism: a saccadic reaction time study using the gap and overlap paradigm
    J N van der Geest
    Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, The Netherlands
    Biol Psychiatry 50:614-9. 2001
    ..CONCLUSIONS: We concluded that autistic children show a lower level of attentional engagement...
  10. ncbi request reprint Effects of object complexity and type on the gaze behavior of children with pervasive developmental disorder
    C Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht and Rudolf Magnus Institute for Neurosciences, Utrecht University, Utrecht, The Netherlands
    Brain Cogn 65:107-11. 2007
    ..The results show no evidence for specific abnormalities in looking behavior to either faces or to complex stimuli in high functioning children with PDD...
  11. ncbi request reprint Face processing in Pervasive Developmental Disorder (PDD): the roles of expertise and spatial frequency
    M A Boeschoten
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    J Neural Transm 114:1619-29. 2007
    ..Importantly, present results argue against the idea that this is due to a reduced face expertise on the part of the children with PDD, but instead support an abnormality in spatial frequency processing...
  12. ncbi request reprint Abnormal spatial frequency processing in high-functioning children with pervasive developmental disorder (PDD)
    M A Boeschoten
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Clin Neurophysiol 118:2076-88. 2007
    ..Therefore, the present study investigated the existence of deficits in spatial frequency processing at an early sensory level in children with PDD...
  13. ncbi request reprint The relationship between local and global processing and the processing of high and low spatial frequencies studied by event-related potentials and source modeling
    M A Boeschoten
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Brain Res Cogn Brain Res 24:228-36. 2005
    ..Thereby, present results extend former results showing that global and local processing is dependent on spatial frequency and mapped retinotopically in the visual cortex...
  14. ncbi request reprint Dose-related effect of methylphenidate on stopping and changing in children with attention-deficit/hyperactivity disorder
    Marijn Lijffijt
    Department of Psychopharmacology, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands
    Eur Psychiatry 21:544-7. 2006
    ..The effect of methylphenidate (MPH) on inhibitory control as assessed by the stop task in children with attention-deficit/hyperactivity disorder (ADHD) could be influenced by task difficulty and may be mediated by attention...
  15. ncbi request reprint Integrity of lateral and feedbackward connections in visual processing in children with pervasive developmental disorder
    C Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht and Rudolf Magnus Institute for Neurosciences, Utrecht, The Netherlands
    Neuropsychologia 45:1293-8. 2007
    ..This effect did not reach significance, which could be due to the small N of the study. Therefore, the data need replication in a study with larger samples before more definitive conclusions can be drawn...
  16. ncbi request reprint Somatotropic-axis deficiency affects brain substrates of selective attention in childhood-onset growth hormone deficient patients
    M Lijffijt
    Department of Psychopharmacology, Utrecht University, Sorbonnelaan 16, 3584 CA, Utrecht, The Netherlands
    Neurosci Lett 353:123-6. 2003
    ..Detection of occasional visual target patterns was impaired in patients. This was paralleled by a reduction in an attention-related brain potential, which has been associated previously with anterior cingulate cortex functioning...
  17. ncbi request reprint Electrocortical reflections of face and gaze processing in children with pervasive developmental disorder
    C Kemner
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    J Child Psychol Psychiatry 47:1063-72. 2006
    ..It is not clear whether the brain activity related to gaze processing is also normal in children with PDD...
  18. ncbi request reprint Time-varying differences in evoked potentials elicited by high versus low spatial frequencies: a topographical and source analysis
    M A Boeschoten
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Clin Neurophysiol 116:1956-66. 2005
    ..An additional question was whether and how a hemispheric balance in spatial frequency processing develops over time...
  19. pmc Inter-rater reliability and stability of diagnoses of autism spectrum disorder in children identified through screening at a very young age
    Emma van Daalen
    Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    Eur Child Adolesc Psychiatry 18:663-74. 2009
    ..In conclusion, the inter-rater reliability and stability of the diagnoses of ASD established at 23 months in this population-based sample of very young children are good...
  20. ncbi request reprint Effects of methylphenidate, desipramine, and L-dopa on attention and inhibition in children with Attention Deficit Hyperactivity Disorder
    C C E Overtoom
    Department of Psychopharmacology, Faculty of Pharmacy, Utrecht University, P O BOX 80082, 3508 TB, Utrecht, The Netherlands
    Behav Brain Res 145:7-15. 2003
    ..It is suggested that the effects of MPH on attention are due to a combination of noradrenergic and dopaminergic mechanisms. The improved inhibition under DMI could be serotonergically mediated...
  21. ncbi request reprint Larger brains in medication naive high-functioning subjects with pervasive developmental disorder
    Saskia J M C Palmen
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    J Autism Dev Disord 34:603-13. 2004
    ....
  22. ncbi request reprint Processing capacity in children and adolescents with pervasive developmental disorders
    Marco R Hoeksma
    Department of Child and Adolescent Psychiatry, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands
    J Autism Dev Disord 34:341-54. 2004
    ..The results suggest that autistic subjects show abnormal capacity allocation. Some of these abnormalities may dissolve over time, while others remain into adolescence...
  23. doi request reprint Cross-sensory gating in schizophrenia and autism spectrum disorder: EEG evidence for impaired brain connectivity?
    Maurice J C M Magnée
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, The Netherlands
    Neuropsychologia 47:1728-32. 2009
    ....
  24. ncbi request reprint Superior disembedding performance of high-functioning individuals with autism spectrum disorders and their parents: the need for subtle measures
    Maretha V de Jonge
    Department of Child and Adolescent Psychiatry, UMC Utrecht, HP B01 201, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Autism Dev Disord 36:677-83. 2006
    ....
  25. doi request reprint Audiovisual speech integration in pervasive developmental disorder: evidence from event-related potentials
    Maurice J C M Magnée
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center, Utrecht, The Netherlands
    J Child Psychol Psychiatry 49:995-1000. 2008
    ..It has been suggested that communicative impairments among individuals with pervasive developmental disorders (PDD) might be caused by an inability to integrate synchronously presented visual and auditory cues...
  26. pmc Brief report: eye movements during visual search tasks indicate enhanced stimulus discriminability in subjects with PDD
    Chantal Kemner
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Autism Dev Disord 38:553-7. 2008
    ..No evidence was found for a different search strategy between the groups. The data indicate an enhanced ability to discriminate between stimulus elements in PDD...
  27. doi request reprint Abnormal timing of visual feedback processing in young adults with schizophrenia
    Chantal Kemner
    Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    Neuropsychologia 47:3105-10. 2009
    ..However, there is little knowledge on the role of feedbackward processing in this group. This question is of importance, as recent studies indicate that feedback processing is critical in stimulus integration...
  28. doi request reprint Attentional effects of gaze shifts are influenced by emotion and spatial frequency, but not in autism
    Maartje Cathelijne de Jong
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Am Acad Child Adolesc Psychiatry 47:443-54. 2008
    ..e., local and global information)...
  29. doi request reprint Finding suitable phenotypes for genetic studies of schizophrenia: heritability and segregation analysis
    Maartje F Aukes
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 64:128-36. 2008
    ..Intermediate phenotypes or endophenotypes may facilitate genetic research if they display a simpler mode of transmission than schizophrenia itself, i.e., if they reflect more closely the underlying genetic effects...
  30. ncbi request reprint Coherent versus component motion perception in autism spectrum disorder
    Myriam W G Vandenbroucke
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, B01 201, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Autism Dev Disord 38:941-9. 2008
    ..A reconciliation of the different outcomes is proposed based on spatial frequency processing in ASD...
  31. ncbi request reprint Facial electromyographic responses to emotional information from faces and voices in individuals with pervasive developmental disorder
    Maurice J C M Magnée
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Child Psychol Psychiatry 48:1122-30. 2007
    ..We aimed to test both automatic processing of facial affect as well as the integration of auditory and visual emotion cues in individuals with PDD...
  32. doi request reprint A neural substrate for atypical low-level visual processing in autism spectrum disorder
    Myriam W G Vandenbroucke
    University Medical Centre Utrecht, Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    Brain 131:1013-24. 2008
    ..In addition, given the reconciliation between our findings and previous neuropathology and neurochemistry research, we suggest that atypical horizontal interactions might reflect a more general neural abnormality in this disorder...
  33. doi request reprint A new approach to the study of detail perception in Autism Spectrum Disorder (ASD): investigating visual feedforward, horizontal and feedback processing
    Myriam W G Vandenbroucke
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands
    Vision Res 49:1006-16. 2009
    ..Interestingly, performance improved in the ASD group when repeating the task two additional times, indicating a compensation for the imbalance between feedforward and feedback processing...
  34. ncbi request reprint Similar facial electromyographic responses to faces, voices, and body expressions
    Maurice J C M Magnée
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neuroreport 18:369-72. 2007
    ..We suggest that seeing a facial expression, an emotional body expression or hearing an emotional tone of voice all activate the affect program corresponding to the emotion displayed...
  35. ncbi request reprint Sources of auditory selective attention and the effects of methylphenidate in children with attention-deficit/hyperactivity disorder
    Chantal Kemner
    Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    Biol Psychiatry 55:776-8. 2004
    ....
  36. ncbi request reprint Inhibition in children with attention-deficit/hyperactivity disorder: a psychophysiological study of the stop task
    Carin C E Overtoom
    Faculty of Pharmacy, Department of Psychopharmacology, Rudolf Magnus Institute for Neurosciences, Utrecht University, P O BOX 80082, 3508 TB Utrecht, The Netherlands
    Biol Psychiatry 51:668-76. 2002
    ..The purpose of the study was to investigate and identify abnormal brain activity, as revealed by event-related potentials (ERPs) concurring with deficient inhibitory control in children with attention-deficit/hyperactivity disorder (ADHD)...
  37. ncbi request reprint Modulating sensorimotor gating in healthy volunteers: the effects of desipramine and haloperidol
    Bob Oranje
    Department of Psychopharmacology, Faculty of Pharmaceutical Sciences, Rudolf Magnus Institute for Neurosciences, Utrecht University, Utrecht, The Netherlands
    Psychiatry Res 127:195-205. 2004
    ..Since no effects on habituation were found, this suggests that neither enhanced noradrenergic nor decreased dopaminergic activity is involved in this process...
  38. ncbi request reprint Variability in spatial normalization of pediatric and adult brain images
    Marco R Hoeksma
    Department of Psychopharmacology, Faculty of Pharmaceutical Sciences, Utrecht University, The Netherlands
    Clin Neurophysiol 116:1188-94. 2005
    ..In this paper we compared the outcome of a linear registration method for brain images of psychiatric and control groups of different ages in order to assess the relative adequacy of normalization in such diverse groups...
  39. ncbi request reprint Brain anatomy in non-affected parents of autistic probands: a MRI study
    Saskia J M C Palmen
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychol Med 35:1411-20. 2005
    ..Identifying structural brain abnormalities under genetic control is of particular importance as these could represent endophenotypes of autism...
  40. ncbi request reprint ERPs and eye movements reflect atypical visual perception in pervasive developmental disorder
    Chantal Kemner
    Rudolf Magnus Institute of Neuroscience, Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, The Netherlands
    J Autism Dev Disord 36:45-54. 2006
    ..It is suggested that subjects with PDD show abnormal activation of visual pathways dedicated to the processing of high and low spatial frequencies...
  41. ncbi request reprint Increased gray-matter volume in medication-naive high-functioning children with autism spectrum disorder
    Saskia J M C Palmen
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychol Med 35:561-70. 2005
    ....
  42. ncbi request reprint Abnormal selective attention normalizes P3 amplitudes in PDD
    Marco R Hoeksma
    Department of Psychopharmacology, Faculty of Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584CA, Utrecht, The Netherlands
    J Autism Dev Disord 36:643-54. 2006
    ..It was concluded that the abnormalities in selective attention in adolescents with PDD have a normalizing effect on P3, and possibly act as a compensatory process...
  43. ncbi request reprint Brief report: can you see what is not there? low-level auditory-visual integration in autism spectrum disorder
    Maarten J van der Smagt
    Experimental Psychology, Helmholtz Institute and Utrecht University, Heidelberglaan 2, Utrecht 3584 CS, The Netherlands
    J Autism Dev Disord 37:2014-9. 2007
    ..This finding implicates that any problems arising from integrating auditory and visual information must stem from higher processing stages in high-functioning adults with Autism Spectrum Disorder...
  44. doi request reprint Reduced error monitoring in children with autism spectrum disorder: an ERP study
    Petra H J M Vlamings
    Department of Neurocognition, Faculty of Psychology, Universiteit Maastricht, The Netherlands
    Eur J Neurosci 28:399-406. 2008
    ..This relates well to the perseverative behaviour that is seen in children with ASD. We discuss these results in terms of a general deficit in self-monitoring, underlying social disturbance in ASD and the involvement of the ACC...
  45. ncbi request reprint Mutation screening and association analysis of six candidate genes for autism on chromosome 7q
    Elena Bonora
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
    Eur J Hum Genet 13:198-207. 2005
    ..Association was also detected for several polymorphisms in the promoter and untranslated region of NRCAM, suggesting that alterations in expression of this gene may be linked to autism susceptibility...
  46. ncbi request reprint Processing speed in recurrent visual networks correlates with general intelligence
    Jacob Jolij
    Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
    Neuroreport 18:39-43. 2007
    ..The hypothesis that a smarter brain runs faster may need to be refined: a smarter brain's feedback connections run faster...
  47. ncbi request reprint Mapping autism risk loci using genetic linkage and chromosomal rearrangements
    Peter Szatmari
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
    Nat Genet 39:319-28. 2007
    ..Neurexins team with previously implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for contributing to ASDs...
  48. ncbi request reprint Autism and visual fixation
    Chantal Kemner
    Am J Psychiatry 160:1358-9; author reply 1359. 2003
  49. ncbi request reprint Methylphenidate improves deficient error evaluation in children with ADHD: an event-related brain potential study
    Lisa M Jonkman
    Faculty of Psychology, Department of Cognitive Neuroscience, Maastricht University, Maastricht, The Netherlands
    Biol Psychol 76:217-29. 2007
    ..Methylphenidate's ameliorating effects might be established through its influence on brain networks including posterior (parietal) cortex, enabling children with ADHD to allocate more attention to significant events...