Casper Jansen

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. doi request reprint Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients
    C Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, The Netherlands
    Neuropathol Appl Neurobiol 35:272-82. 2009
  2. ncbi request reprint [Eleven years of autopsy on account of Creutzfeldt-Jakob disease in the Netherlands]
    Casper Jansen
    Universitair Medisch Centrum Utrecht, Nederlands Surveillance Centrum voor Prionziekten, afd Pathologie, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 153:A172. 2009
  3. pmc Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 7:e36333. 2012
  4. pmc Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, 3584 CX Utrecht, The Netherlands
    Acta Neuropathol 119:189-97. 2010
  5. doi request reprint Inherited Creutzfeldt-Jakob disease in a Dutch patient with a novel five octapeptide repeat insertion and unusual cerebellar morphology
    C Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 80:1386-9. 2009
  6. pmc A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Acta Neuropathol 121:59-68. 2011
  7. doi request reprint The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype
    C Jansen
    Department of Pathology, Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 81:1052-5. 2010
  8. doi request reprint A second case of Gerstmann-Sträussler-Scheinker disease linked to the G131V mutation in the prion protein gene in a Dutch patient
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neuropathol Exp Neurol 70:698-702. 2011
  9. ncbi request reprint [The first patient with the new variant of Creutzfeldt-Jakob's disease in The Netherlands]
    C Jansen
    afd Pathologie, Universitair Medisch Centrum Utrecht, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 149:2949-54. 2005

Detail Information

Publications9

  1. doi request reprint Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients
    C Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, The Netherlands
    Neuropathol Appl Neurobiol 35:272-82. 2009
    ..PECJD has rarely been described in Caucasians and debate continues on its classification and pathogenesis. We describe our experience of PECJD over a 14-year period of surveillance for CJD in the Netherlands and the UK...
  2. ncbi request reprint [Eleven years of autopsy on account of Creutzfeldt-Jakob disease in the Netherlands]
    Casper Jansen
    Universitair Medisch Centrum Utrecht, Nederlands Surveillance Centrum voor Prionziekten, afd Pathologie, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 153:A172. 2009
    ..To describe our experience with the diagnostics of Creutzfeldt-Jakob disease (CJD) and other prion diseases in the Netherlands over a period of 11 years (1997-2007)...
  3. pmc Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 7:e36333. 2012
    ..The unusual incidence of the VV2 sCJD subtype compared to that reported to date in other Western countries deserves further investigation...
  4. pmc Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, 3584 CX Utrecht, The Netherlands
    Acta Neuropathol 119:189-97. 2010
    ..Furthermore, it confirms that the absence of the glycosylphosphatidylinositol anchor in PrP predisposes to amyloid plaque formation...
  5. doi request reprint Inherited Creutzfeldt-Jakob disease in a Dutch patient with a novel five octapeptide repeat insertion and unusual cerebellar morphology
    C Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 80:1386-9. 2009
    ....
  6. pmc A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Acta Neuropathol 121:59-68. 2011
    ....
  7. doi request reprint The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype
    C Jansen
    Department of Pathology, Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 81:1052-5. 2010
    ..Our report on the first Dutch patient with PSPr further expands the spectrum of prionopathies and exemplifies the need to re-evaluate cases of atypical prion disease...
  8. doi request reprint A second case of Gerstmann-Sträussler-Scheinker disease linked to the G131V mutation in the prion protein gene in a Dutch patient
    Casper Jansen
    Dutch Surveillance Centre for Prion Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neuropathol Exp Neurol 70:698-702. 2011
    ..To our knowledge, this is the second family worldwide in which this mutation has been identified. Gerstmann-Sträussler-Scheinker disease should be considered in patients with a clinical diagnosis of familial frontotemporal dementia...
  9. ncbi request reprint [The first patient with the new variant of Creutzfeldt-Jakob's disease in The Netherlands]
    C Jansen
    afd Pathologie, Universitair Medisch Centrum Utrecht, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 149:2949-54. 2005
    ..In patients with rapidly progressive psychiatric symptoms and unexplained neurological signs, particularly sensory complaints, one must consider the possibility of vCJD...