Research Topics
| Gerry JagerSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Cannabis use and memory brain function in adolescent boys: a cross-sectional multicenter functional magnetic resonance imaging studyGerry Jager
Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
J Am Acad Child Adolesc Psychiatry 49:561-72, 572.e1-3. 2010..Prefrontal and temporal regions are critically involved in these functions. Maturational processes leave these brain areas prone to the potentially harmful effects of cannabis use...
Long-term consequences of adolescent cannabis exposure on the development of cognition, brain structure and function: an overview of animal and human researchGerry Jager
Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, The Netherlands
Curr Drug Abuse Rev 1:114-23. 2008....- Incidental use of ecstasy: no evidence for harmful effects on cognitive brain function in a prospective fMRI studyGerry Jager
Department of Neurosurgery, A 01 126, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Psychopharmacology (Berl) 193:403-14. 2007..There is concern that even a single dose of 3,4-methylenedioxymethamphetamine may be neurotoxic, but very little is known about the consequences of a low dose of ecstasy for cognitive brain function... - Assessment of cognitive brain function in ecstasy users and contributions of other drugs of abuse: results from an FMRI studyGerry Jager
Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
Neuropsychopharmacology 33:247-58. 2008..This could be related to the different neurotransmitter systems these drugs predominantly act upon, that is, serotonin (ecstasy) vs dopamine (amphetamine) systems... - Effects of frequent cannabis use on hippocampal activity during an associative memory taskGerry Jager
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Eur Neuropsychopharmacol 17:289-97. 2007..Therefore, lower brain activation may not signify neurocognitive impairment, but could be the expression of a non-cognitive variable related to frequent cannabis use, for example changes in cerebral perfusion or differences in vigilance... - Long-term effects of frequent cannabis use on working memory and attention: an fMRI studyGerry Jager
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Psychopharmacology (Berl) 185:358-68. 2006..It is not clear, however, whether these effects also occur with moderate, recreational use of cannabis. Furthermore, little is known about underlying brain correlates... 
Effects of Δ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI studyMatthijs G Bossong
University Medical Center Utrecht, The Netherlands
J Cogn Neurosci 24:588-99. 2012..These results further emphasize the eCB system as a potential novel target for treatment of memory disorders and a promising target for development of new therapies to reduce memory deficits in humans...- Evidence for involvement of the insula in the psychotropic effects of THC in humans: a double-blind, randomized pharmacological MRI studyHendrika H Van Hell
Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
Int J Neuropsychopharmacol 14:1377-88. 2011..These changes may represent the THC-induced neurophysiological correlates of feeling high. The alterations in baseline brain perfusion and activity also have relevance for studies on task-related effects of THC on brain function... - Effects of δ9-tetrahydrocannabinol on human working memory functionMatthijs G Bossong
Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
Biol Psychiatry 71:693-9. 2012..These findings suggest the possibility that the eCB system is also involved in WM deficits in schizophrenia. In the present study, we examined if perturbation of the eCB system can induce abnormal WM activity in healthy subjects... - Involvement of the endocannabinoid system in reward processing in the human brainHendrika H Van Hell
Department of Neurology and Neurosurgery, G 03 124, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Psychopharmacology (Berl) 219:981-90. 2012..The endocannabinoid (eCB) system has been implicated in reward processing in animals, but in humans, the relation between eCB functioning and reward is less clear... - Methods of the pharmacological imaging of the cannabinoid system (PhICS) study: towards understanding the role of the brain endocannabinoid system in human cognitionHendrika H Van Hell
Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
Int J Methods Psychiatr Res 20:10-27. 2011.... - Automatization and working memory capacity in schizophreniaTamar R van Raalten
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, The Netherlands
Schizophr Res 100:161-71. 2008..This suggests that inefficient WM function and reduced capacity may be related to an inability to process information requiring frequent updating... - Chronic effects of cannabis use on the human reward system: an fMRI studyHendrika H Van Hell
Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, Section Brain Function and Plasticity, University Medical Center, Utrecht, The Netherlands
Eur Neuropsychopharmacol 20:153-63. 2010..Our findings imply that chronic cannabis use as well as nicotine, may cause an altered brain response to rewarding stimuli... - Sex differences for selective forms of spatial memoryAlbert Postma
Psychological Laboratory, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
Brain Cogn 54:24-34. 2004..Together, these findings provide further insight in the specificity of sex differences in spatial memory and in the functional architecture of spatial memory. Implications for the relevant evolutionary basis are discussed... - On the hemispheric specialization for categorical and coordinate spatial relations: a review of the current evidenceGerry Jager
Psychological Laboratory, Utrecht University, Heidelberglaan 2, NL-3584 CS, Utrecht, The Netherlands
Neuropsychologia 41:504-15. 2003..The pattern appears to be critically linked to receptive field properties of the two hemispheres and as such is modulated by certain elementary visual characteristics of the displayed stimuli... - Ecstasy use and self-reported depression, impulsivity, and sensation seeking: a prospective cohort studyMaartje M L de Win
Department of Radiology, University of Amsterdam, Academic Medical Center, The Netherlands
J Psychopharmacol 20:226-35. 2006..However, low level ecstasy use may increase (certain aspects of) sensation seeking... - Cognition in novice ecstasy users with minimal exposure to other drugs: a prospective cohort studyThelma Schilt
Amsterdam Institute for Addiction Research, The Netherlands
Arch Gen Psychiatry 64:728-36. 2007..However, owing to the cross-sectional and retrospective nature of currently available studies, questions remain regarding the causal direction and clinical relevance of these findings... - A prospective cohort study on sustained effects of low-dose ecstasy use on the brain in new ecstasy usersMaartje M L de Win
Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Neuropsychopharmacology 32:458-70. 2007..Additional studies are needed to replicate these findings... - The Netherlands XTC Toxicity (NeXT) study: objectives and methods of a study investigating causality, course, and clinical relevanceMaartje M L de Win
Department of Radiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Int J Methods Psychiatr Res 14:167-85. 2005..The combined results will lead to conclusions that can be used in prevention messages, clinical decision making, and the development of an (inter)national ecstasy policy...