Gerry Jager

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Cannabis use and memory brain function in adolescent boys: a cross-sectional multicenter functional magnetic resonance imaging study
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    J Am Acad Child Adolesc Psychiatry 49:561-72, 572.e1-3. 2010
  2. ncbi Long-term consequences of adolescent cannabis exposure on the development of cognition, brain structure and function: an overview of animal and human research
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, The Netherlands
    Curr Drug Abuse Rev 1:114-23. 2008
  3. ncbi Incidental use of ecstasy: no evidence for harmful effects on cognitive brain function in a prospective fMRI study
    Gerry Jager
    Department of Neurosurgery, A 01 126, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychopharmacology (Berl) 193:403-14. 2007
  4. ncbi Assessment of cognitive brain function in ecstasy users and contributions of other drugs of abuse: results from an FMRI study
    Gerry Jager
    Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neuropsychopharmacology 33:247-58. 2008
  5. ncbi Effects of frequent cannabis use on hippocampal activity during an associative memory task
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Eur Neuropsychopharmacol 17:289-97. 2007
  6. ncbi Long-term effects of frequent cannabis use on working memory and attention: an fMRI study
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Psychopharmacology (Berl) 185:358-68. 2006
  7. doi Effects of Δ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI study
    Matthijs G Bossong
    University Medical Center Utrecht, The Netherlands
    J Cogn Neurosci 24:588-99. 2012
  8. ncbi The endocannabinoid system and emotional processing: a pharmacological fMRI study with ∆9-tetrahydrocannabinol
    Matthijs G Bossong
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands Institute of Psychiatry, Department of Psychosis Studies PO67, King s College London, 16 De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Eur Neuropsychopharmacol 23:1687-97. 2013
  9. doi Evidence for involvement of the insula in the psychotropic effects of THC in humans: a double-blind, randomized pharmacological MRI study
    Hendrika H Van Hell
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Neuropsychopharmacol 14:1377-88. 2011
  10. doi Effects of δ9-tetrahydrocannabinol on human working memory function
    Matthijs G Bossong
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Biol Psychiatry 71:693-9. 2012

Collaborators

Detail Information

Publications21

  1. pmc Cannabis use and memory brain function in adolescent boys: a cross-sectional multicenter functional magnetic resonance imaging study
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    J Am Acad Child Adolesc Psychiatry 49:561-72, 572.e1-3. 2010
    ..Prefrontal and temporal regions are critically involved in these functions. Maturational processes leave these brain areas prone to the potentially harmful effects of cannabis use...
  2. ncbi Long-term consequences of adolescent cannabis exposure on the development of cognition, brain structure and function: an overview of animal and human research
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, The Netherlands
    Curr Drug Abuse Rev 1:114-23. 2008
    ....
  3. ncbi Incidental use of ecstasy: no evidence for harmful effects on cognitive brain function in a prospective fMRI study
    Gerry Jager
    Department of Neurosurgery, A 01 126, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychopharmacology (Berl) 193:403-14. 2007
    ..There is concern that even a single dose of 3,4-methylenedioxymethamphetamine may be neurotoxic, but very little is known about the consequences of a low dose of ecstasy for cognitive brain function...
  4. ncbi Assessment of cognitive brain function in ecstasy users and contributions of other drugs of abuse: results from an FMRI study
    Gerry Jager
    Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neuropsychopharmacology 33:247-58. 2008
    ..This could be related to the different neurotransmitter systems these drugs predominantly act upon, that is, serotonin (ecstasy) vs dopamine (amphetamine) systems...
  5. ncbi Effects of frequent cannabis use on hippocampal activity during an associative memory task
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Eur Neuropsychopharmacol 17:289-97. 2007
    ..Therefore, lower brain activation may not signify neurocognitive impairment, but could be the expression of a non-cognitive variable related to frequent cannabis use, for example changes in cerebral perfusion or differences in vigilance...
  6. ncbi Long-term effects of frequent cannabis use on working memory and attention: an fMRI study
    Gerry Jager
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, A 01 126, University Medical Center, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Psychopharmacology (Berl) 185:358-68. 2006
    ..It is not clear, however, whether these effects also occur with moderate, recreational use of cannabis. Furthermore, little is known about underlying brain correlates...
  7. doi Effects of Δ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI study
    Matthijs G Bossong
    University Medical Center Utrecht, The Netherlands
    J Cogn Neurosci 24:588-99. 2012
    ..These results further emphasize the eCB system as a potential novel target for treatment of memory disorders and a promising target for development of new therapies to reduce memory deficits in humans...
  8. ncbi The endocannabinoid system and emotional processing: a pharmacological fMRI study with ∆9-tetrahydrocannabinol
    Matthijs G Bossong
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands Institute of Psychiatry, Department of Psychosis Studies PO67, King s College London, 16 De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    Eur Neuropsychopharmacol 23:1687-97. 2013
    ..Our findings also suggest a possible role for the endocannabinoid system in abnormal emotional processing, and may thus be relevant for psychiatric disorders such as major depression. ..
  9. doi Evidence for involvement of the insula in the psychotropic effects of THC in humans: a double-blind, randomized pharmacological MRI study
    Hendrika H Van Hell
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Neuropsychopharmacol 14:1377-88. 2011
    ..These changes may represent the THC-induced neurophysiological correlates of feeling high. The alterations in baseline brain perfusion and activity also have relevance for studies on task-related effects of THC on brain function...
  10. doi Effects of δ9-tetrahydrocannabinol on human working memory function
    Matthijs G Bossong
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Biol Psychiatry 71:693-9. 2012
    ..These findings suggest the possibility that the eCB system is also involved in WM deficits in schizophrenia. In the present study, we examined if perturbation of the eCB system can induce abnormal WM activity in healthy subjects...
  11. pmc Involvement of the endocannabinoid system in reward processing in the human brain
    Hendrika H Van Hell
    Department of Neurology and Neurosurgery, G 03 124, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Psychopharmacology (Berl) 219:981-90. 2012
    ..The endocannabinoid (eCB) system has been implicated in reward processing in animals, but in humans, the relation between eCB functioning and reward is less clear...
  12. doi Methods of the pharmacological imaging of the cannabinoid system (PhICS) study: towards understanding the role of the brain endocannabinoid system in human cognition
    Hendrika H Van Hell
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Int J Methods Psychiatr Res 20:10-27. 2011
    ....
  13. pmc Default mode network in the effects of Δ9-Tetrahydrocannabinol (THC) on human executive function
    Matthijs G Bossong
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS ONE 8:e70074. 2013
    ..This may be relevant for psychiatric disorders associated with executive function deficits, such as schizophrenia and ADHD. ..
  14. doi Chronic effects of cannabis use on the human reward system: an fMRI study
    Hendrika H Van Hell
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, Section Brain Function and Plasticity, University Medical Center, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 20:153-63. 2010
    ..Our findings imply that chronic cannabis use as well as nicotine, may cause an altered brain response to rewarding stimuli...
  15. ncbi Automatization and working memory capacity in schizophrenia
    Tamar R van Raalten
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, The Netherlands
    Schizophr Res 100:161-71. 2008
    ..This suggests that inefficient WM function and reduced capacity may be related to an inability to process information requiring frequent updating...
  16. ncbi Sex differences for selective forms of spatial memory
    Albert Postma
    Psychological Laboratory, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
    Brain Cogn 54:24-34. 2004
    ..Together, these findings provide further insight in the specificity of sex differences in spatial memory and in the functional architecture of spatial memory. Implications for the relevant evolutionary basis are discussed...
  17. ncbi On the hemispheric specialization for categorical and coordinate spatial relations: a review of the current evidence
    Gerry Jager
    Psychological Laboratory, Utrecht University, Heidelberglaan 2, NL 3584 CS, Utrecht, The Netherlands
    Neuropsychologia 41:504-15. 2003
    ..The pattern appears to be critically linked to receptive field properties of the two hemispheres and as such is modulated by certain elementary visual characteristics of the displayed stimuli...
  18. ncbi Cognition in novice ecstasy users with minimal exposure to other drugs: a prospective cohort study
    Thelma Schilt
    Amsterdam Institute for Addiction Research, The Netherlands
    Arch Gen Psychiatry 64:728-36. 2007
    ..However, owing to the cross-sectional and retrospective nature of currently available studies, questions remain regarding the causal direction and clinical relevance of these findings...
  19. ncbi Ecstasy use and self-reported depression, impulsivity, and sensation seeking: a prospective cohort study
    Maartje M L de Win
    Department of Radiology, University of Amsterdam, Academic Medical Center, The Netherlands
    J Psychopharmacol 20:226-35. 2006
    ..However, low level ecstasy use may increase (certain aspects of) sensation seeking...
  20. ncbi A prospective cohort study on sustained effects of low-dose ecstasy use on the brain in new ecstasy users
    Maartje M L de Win
    Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neuropsychopharmacology 32:458-70. 2007
    ..Additional studies are needed to replicate these findings...
  21. ncbi The Netherlands XTC Toxicity (NeXT) study: objectives and methods of a study investigating causality, course, and clinical relevance
    Maartje M L de Win
    Department of Radiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Int J Methods Psychiatr Res 14:167-85. 2005
    ..The combined results will lead to conclusions that can be used in prevention messages, clinical decision making, and the development of an (inter)national ecstasy policy...