J J Hoozemans

Summary

Affiliation: University Hospital Vrije Universiteit
Country: The Netherlands

Publications

  1. ncbi request reprint Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain
    J J Hoozemans
    Department of Pathology, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands
    Acta Neuropathol 101:2-8. 2001
  2. ncbi request reprint Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease
    J J Hoozemans
    Department of Psychiatry, Research Institute Neurosciences Vrije Universiteit, Vrije Universiteit, Amsterdam, The Netherlands
    Exp Gerontol 36:559-70. 2001
  3. ncbi request reprint Immunological aspects of alzheimer's disease: therapeutic implications
    J J Hoozemans
    Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    BioDrugs 15:325-37. 2001
  4. ncbi request reprint Complement C1-inhibitor expression in Alzheimer's disease
    R Veerhuis
    Department of Psychiatry, Research Institute Neurosciences Vrije Universiteit, Graduate School Neurosciences Amsterdam, The Netherlands
    Acta Neuropathol 96:287-96. 1998
  5. ncbi request reprint Establishment of microglial cell cultures derived from postmortem human adult brain tissue: immunophenotypical and functional characterization
    C J De Groot
    Research Institute Neurosciences Vrije Universiteit Amsterdam, Department of Pathology, University Hospital, Vrije Universiteit, The Netherlands
    Microsc Res Tech 54:34-9. 2001

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain
    J J Hoozemans
    Department of Pathology, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands
    Acta Neuropathol 101:2-8. 2001
    ..The different distribution patterns of COX-1 and COX-2 in AD could implicate that these enzymes are involved in different cellular processes in the pathogenesis of AD...
  2. ncbi request reprint Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease
    J J Hoozemans
    Department of Psychiatry, Research Institute Neurosciences Vrije Universiteit, Vrije Universiteit, Amsterdam, The Netherlands
    Exp Gerontol 36:559-70. 2001
    ..Although the physiological role of neuronal COX-2 still remains unclear, we suggest an interplay between glial derived IL-1 and neuronal upregulation of COX-2 expression in chronic neurodegenerative diseases, such as AD...
  3. ncbi request reprint Immunological aspects of alzheimer's disease: therapeutic implications
    J J Hoozemans
    Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    BioDrugs 15:325-37. 2001
    ..This review outlines the pathological and genetic evidence that an inflammatory mechanism is involved in AD and the therapeutic approaches based on inhibition or mediation of inflammation...
  4. ncbi request reprint Complement C1-inhibitor expression in Alzheimer's disease
    R Veerhuis
    Department of Psychiatry, Research Institute Neurosciences Vrije Universiteit, Graduate School Neurosciences Amsterdam, The Netherlands
    Acta Neuropathol 96:287-96. 1998
    ....
  5. ncbi request reprint Establishment of microglial cell cultures derived from postmortem human adult brain tissue: immunophenotypical and functional characterization
    C J De Groot
    Research Institute Neurosciences Vrije Universiteit Amsterdam, Department of Pathology, University Hospital, Vrije Universiteit, The Netherlands
    Microsc Res Tech 54:34-9. 2001
    ..Upon stimulation with lipopolysaccharide (LPS), microglial cells secreted pro- and antiinflammatory mediators, i.e., interleukin- (IL)-6, prostaglandin E2 (PGE2), and IL-10, indicating the functional capacity of cultured microglia...