Pieter J Hoekstra

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. pmc Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study
    Yingfang Tian
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    BMC Med Genomics 5:49. 2012
  2. ncbi Tic disorders and obsessive-compulsive disorder: is autoimmunity involved?
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Centre, Groningen, The Netherlands
    Int Rev Psychiatry 17:497-502. 2005
  3. doi Plasma kynurenine and related measures in tic disorder patients
    Pieter J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, P O Box 660, 9700 AR, Groningen, The Netherlands
    Eur Child Adolesc Psychiatry 16:71-7. 2007
  4. pmc Risperidone-induced weight gain in referred children with autism spectrum disorders is associated with a common polymorphism in the 5-hydroxytryptamine 2C receptor gene
    Pieter J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 20:473-7. 2010
  5. doi Dopamine transporter gene moderates response to behavioral parent training in children with ADHD: a pilot study
    Barbara J van den Hoofdakker
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Dev Psychol 48:567-74. 2012
  6. doi Variants of the SLC6A3 (DAT1) polymorphism affect performance monitoring-related cortical evoked potentials that are associated with ADHD
    Monika Althaus
    Department of Psychiatry, University Medical Centre Groningen, University of Groningen, The Netherlands
    Biol Psychol 85:19-32. 2010
  7. pmc Perinatal risk factors interacting with catechol O-methyltransferase and the serotonin transporter gene predict ASD symptoms in children with ADHD
    Judith S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands
    J Child Psychol Psychiatry 51:1242-50. 2010
  8. ncbi Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Clin Psychopharmacol 27:52-7. 2007
  9. doi Baroreflex sensitivity during rest and executive functioning in attention-deficit/hyperactivity disorder. The TRAILS study
    Andrea Dietrich
    Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    Biol Psychol 90:249-57. 2012
  10. doi Long-term treatment with atomoxetine for attention-deficit/hyperactivity disorder symptoms in children and adolescents with autism spectrum disorder: an open-label extension study
    Myriam Harfterkamp
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 23:194-9. 2013

Detail Information

Publications33

  1. pmc Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study
    Yingfang Tian
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    BMC Med Genomics 5:49. 2012
    ..This study determined if gene expression in blood correlated significantly with IA and/or HI rating scale scores in participants with TS...
  2. ncbi Tic disorders and obsessive-compulsive disorder: is autoimmunity involved?
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Centre, Groningen, The Netherlands
    Int Rev Psychiatry 17:497-502. 2005
    ..Future longitudinal studies should be aimed at assessing the precise relationship between symptom exacerbations, infections, and immune parameters, possibly along with gene expression profiles...
  3. doi Plasma kynurenine and related measures in tic disorder patients
    Pieter J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, P O Box 660, 9700 AR, Groningen, The Netherlands
    Eur Child Adolesc Psychiatry 16:71-7. 2007
    ..In the present study, we examined plasma levels of kynurenine and related molecules in a group of tic disorder patients...
  4. pmc Risperidone-induced weight gain in referred children with autism spectrum disorders is associated with a common polymorphism in the 5-hydroxytryptamine 2C receptor gene
    Pieter J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 20:473-7. 2010
    ..Younger children and those treated with higher doses of risperidone may be at higher risk for weight gain...
  5. doi Dopamine transporter gene moderates response to behavioral parent training in children with ADHD: a pilot study
    Barbara J van den Hoofdakker
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Dev Psychol 48:567-74. 2012
    ....
  6. doi Variants of the SLC6A3 (DAT1) polymorphism affect performance monitoring-related cortical evoked potentials that are associated with ADHD
    Monika Althaus
    Department of Psychiatry, University Medical Centre Groningen, University of Groningen, The Netherlands
    Biol Psychol 85:19-32. 2010
    ..Only these two components discriminated between the DAT1 10/10R and 9R carriers. The 10/10R carriers showed a smaller Pe to errors and a smaller SPN in anticipation of negative feedback, particularly with learning...
  7. pmc Perinatal risk factors interacting with catechol O-methyltransferase and the serotonin transporter gene predict ASD symptoms in children with ADHD
    Judith S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands
    J Child Psychol Psychiatry 51:1242-50. 2010
    ....
  8. ncbi Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Clin Psychopharmacol 27:52-7. 2007
    ..Little is known about the role of CYP2D6 polymorphism in risperidone-induced prolactin release in children...
  9. doi Baroreflex sensitivity during rest and executive functioning in attention-deficit/hyperactivity disorder. The TRAILS study
    Andrea Dietrich
    Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    Biol Psychol 90:249-57. 2012
    ..Findings suggest afferent influences of the body's visceral state on higher-order cognitive functioning and imply energetic state dysregulation in ADHD...
  10. doi Long-term treatment with atomoxetine for attention-deficit/hyperactivity disorder symptoms in children and adolescents with autism spectrum disorder: an open-label extension study
    Myriam Harfterkamp
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 23:194-9. 2013
    ..The efficacy and tolerability of long-term treatment with atomoxetine for symptoms of attention-deficit/hyperactivity disorder (ADHD) in children with autism spectrum disorder (ASD) has not been established...
  11. ncbi Long-term effects of risperidone in children with autism spectrum disorders: a placebo discontinuation study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Am Acad Child Adolesc Psychiatry 44:1137-44. 2005
    ..The short-term benefit of risperidone in ameliorating severe disruptive behavior in pediatric patients with autism spectrum disorders is well established; however, only one placebo-controlled, long-term study of efficacy is available...
  12. doi A randomized double-blind study of atomoxetine versus placebo for attention-deficit/hyperactivity disorder symptoms in children with autism spectrum disorder
    Myriam Harfterkamp
    University Medical Center Groningen, The Netherlands
    J Am Acad Child Adolesc Psychiatry 51:733-41. 2012
    ..The efficacy of atomoxetine as treatment of symptoms of attention-deficit/hyperactivity disorder (ADHD) in patients with autism spectrum disorder (ASD) has not been established...
  13. doi The DRD4 gene and severity of tics and comorbid symptoms: main effects and interactions with delivery complications
    Netty G P Bos-Veneman
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Mov Disord 25:1470-6. 2010
    ....
  14. doi Cortisol in the morning and dimensions of anxiety, depression, and aggression in children from a general population and clinic-referred cohort: An integrated analysis. The TRAILS study
    Andrea Dietrich
    Child and Adolescent Psychiatry, Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Psychoneuroendocrinology 38:1281-98. 2013
    ..Therefore, the present results shed doubt on the relevance of single day cortisol measurements for problem behaviors in the milder range. Associations may be stronger in more severe or persistent psychopathology...
  15. ncbi Atomoxetine for attention-deficit/hyperactivity disorder symptoms in children with pervasive developmental disorders: a pilot study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 16:611-9. 2006
    ..This pilot study examined the effects of atomoxetine on attention-deficit/hyperactivity disorder (ADHD) symptoms and autistic features in children with pervasive developmental disorders (PDD)...
  16. ncbi Neuropsychological effects of risperidone in children with pervasive developmental disorders: a blinded discontinuation study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 16:561-73. 2006
    ..Little is known about the neuropsychological effects of risperidone in children with pervasive developmental disorders...
  17. pmc Validity of the Children's Social Behavior Questionnaire (CSBQ) in children with intellectual disability: comparing the CSBQ with ADI-R, ADOS, and clinical DSM-IV-TR classification
    Annelies de Bildt
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Autism Dev Disord 39:1464-70. 2009
    ..The CSBQ may be used as a signaling, screening, or describing instrument for children with ASD and ID, as it complements other methods by adding unique information about the clinical presentation...
  18. doi Differential effects of 5-HTTLPR and DRD2/ANKK1 polymorphisms on electrocortical measures of error and feedback processing in children
    Monika Althaus
    Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Clin Neurophysiol 120:93-107. 2009
    ....
  19. pmc Identifying loci for the overlap between attention-deficit/hyperactivity disorder and autism spectrum disorder using a genome-wide QTL linkage approach
    Judith S Nijmeijer
    University Medical Center Groningen, Groningen, The Netherlands
    J Am Acad Child Adolesc Psychiatry 49:675-85. 2010
    ..The genetic basis for autism spectrum disorder (ASD) symptoms in children with attention-deficit/hyperactivity disorder (ADHD) was addressed using a genome-wide linkage approach...
  20. ncbi Association of common cold with exacerbations in pediatric but not adult patients with tic disorder: a prospective longitudinal study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 15:285-92. 2005
    ..Thus, this study points to a hitherto unknown association of common viral infections with tic exacerbations in children, which may support the involvement of immune dysregulation in tic disorders...
  21. doi Environmental factors in Tourette syndrome
    Pieter J Hoekstra
    Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 37:1040-9. 2013
    ..New studies on large prospective cohorts of patients of different age and the identification of reliable biomarkers or endophenotypes indicating early, prenatal exposure to environmental insults are needed...
  22. pmc Altered immunoglobulin profiles in children with Tourette syndrome
    Netty G P Bos-Veneman
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    Brain Behav Immun 25:532-8. 2011
    ..Post-infectious autoimmunity and immune deficiency have been implicated in the pathogenesis of Tourette syndrome (TS). We asked here whether B cell immunity of patients with TS differs from healthy subjects...
  23. doi Role of perinatal adversities on tic severity and symptoms of attention deficit/hyperactivity disorder in children and adolescents with a tic disorder
    Netty G P Bos-Veneman
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Dev Behav Pediatr 31:100-6. 2010
    ..To investigate the role of perinatal adversities with regard to tic severity and comorbid attention deficit/hyperactivity disorder (ADHD) symptoms in children with a tic disorder...
  24. ncbi Relative contribution of attention-deficit hyperactivity disorder, obsessive-compulsive disorder, and tic severity to social and behavioral problems in tic disorders
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Dev Behav Pediatr 25:272-9. 2004
    ..There was no significant correlation between tic severity and ADHD severity. Thus, in patients with a tic disorder, the presence and severity of ADHD are the main predictors of associated behavioral and social problems...
  25. ncbi Attention-deficit/hyperactivity disorder and social dysfunctioning
    Judith S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Clin Psychol Rev 28:692-708. 2008
    ..Future research should address the exact nature and long-term consequences of social dysfunctioning in children with ADHD, and focus on development of effective treatment strategies...
  26. doi Cytokines and soluble adhesion molecules in children and adolescents with a tic disorder
    Netty G P Bos-Veneman
    Department of Psychiatry, University Medical Center Groningen, P O Box 660, 9700 AR, Groningen, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 34:1390-5. 2010
    ..Dysregulation of the immune system may play a role in tic disorders. We screened for immune disturbances by investigating serum levels of cytokines and soluble adhesion molecules in patients with a tic disorder...
  27. doi Behavioral parent training as an adjunct to routine care in children with attention-deficit/hyperactivity disorder: moderators of treatment response
    Barbara J van den Hoofdakker
    University Center of Child and Adolescent Psychiatry, P O Box 660, 9700 AR Groningen, The Netherlands
    J Pediatr Psychol 35:317-26. 2010
    ..To investigate predictors and moderators of outcome of behavioral parent training (BPT) as adjunct to ongoing routine clinical care (RCC), versus RCC alone...
  28. doi Association of childhood attention-deficit/hyperactivity disorder with atopic diseases and skin infections? A matched case-control study using the General Practice Research Database
    Eelko Hak
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Ann Allergy Asthma Immunol 111:102-106.e2. 2013
    ..Data to support the hypothesis of a relationship between attention-deficit/hyperactivity disorder (ADHD) and allergies are conflicting...
  29. doi Effects of controlled discontinuation of long-term used antipsychotics on weight and metabolic parameters in individuals with intellectual disability
    Gerda de Kuijper
    Vanboeijen, Intellectual Disability Center, Assen, The Netherlands
    J Clin Psychopharmacol 33:520-4. 2013
    ..In conclusion, results of the study show the beneficial effects of discontinuation of long-term used antipsychotics on metabolic outcomes...
  30. doi Antibodies to infectious agents and the positive symptom dimension of subclinical psychosis: The TRAILS study
    Hao Wang
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Schizophr Res 129:47-51. 2011
    ....
  31. ncbi Lack of effect of intravenous immunoglobulins on tics: a double-blind placebo-controlled study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Clin Psychiatry 65:537-42. 2004
    ..No data are available on the effectiveness of intravenous immunoglobulins (IVIG) on tic severity in unselected tic disorder patients...
  32. ncbi Elevated binding of D8/17-specific monoclonal antibody to B lymphocytes in Tic disorder patients
    Pieter J Hoekstra
    Am J Psychiatry 161:1501-2. 2004
  33. ncbi Increased seroreactivity in tic disorder patients to a 60 kDa protein band from a neuronal cell line
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Neuroimmunol 141:118-24. 2003
    ..0%) and healthy controls (41.9%). Sequence analysis of the 60 kDa protein band identified this as a ubiquitous heat shock protein. However, the involvement of other autoantigens with a molecular weight of 60 kDa cannot be excluded...