Eelko Hak

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. pmc Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma: bidirectional crossover study using the general practice research database
    Eelko Hak
    Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University Groningen, Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    Drug Saf 36:1097-104. 2013
  2. pmc Prevalence and predictors of over-the-counter medication use among pregnant women: a cross-sectional study in the Netherlands
    Gwenny Mpj Verstappen
    University Center for Pharmacy, Pharmacoepidemiology and Pharmacoeconomics, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    BMC Public Health 13:185. 2013
  3. doi request reprint Association of childhood attention-deficit/hyperactivity disorder with atopic diseases and skin infections? A matched case-control study using the General Practice Research Database
    Eelko Hak
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Ann Allergy Asthma Immunol 111:102-106.e2. 2013
  4. doi request reprint Association of infant pneumococcal vaccination with pneumococcal pneumonia among mothers: a nested case-control study using the GPRD
    Eelko Hak
    Unit of Pharmaco epidemiology and Pharmaco economics, Department of Pharmacy, University Groningen, The Netherlands
    Vaccine 31:1590-6. 2013
  5. pmc Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial
    Janna M Munster
    University of Groningen, University Centre for Pharmacy, Pharmacoepidemiology and Pharmacoeconomics, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    BMC Womens Health 10:32. 2010
  6. doi request reprint Assessing the effect of a guideline change on drug use prevalence by including the birth cohort dimension: the case of benzodiazepines
    Maarten J Bijlsma
    Unit Pharmacoepidemiology and Pharmacoeconomics PE2, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Pharmacoepidemiol Drug Saf 22:933-41. 2013
  7. ncbi request reprint Cost-effectiveness of statins for primary prevention in patients newly diagnosed with type 2 diabetes in the Netherlands
    Folgerdiena M de Vries
    Department of Pharmacy, Unit of PharmacoEpidemiology and PharmacoEconomics PE2, University of Groningen, Groningen, The Netherlands Electronic address
    Value Health 17:223-30. 2014
  8. pmc Planning and process evaluation of a multi-faceted influenza vaccination implementation strategy for health care workers in acute health care settings
    Josien Riphagen-Dalhuisen
    Department of Pharmacoepidemiology and Pharmacoeconomics, University Centre of Pharmacy, University of Groningen, A Deusinglaan 1, P O Box XB45, Groningen 9713 AV, The Netherlands
    BMC Infect Dis 13:235. 2013
  9. ncbi request reprint Cost effectiveness of pneumococcal vaccination among Dutch infants: economic analysis of the seven valent pneumococcal conjugated vaccine and forecast for the 10 valent and 13 valent vaccines
    Mark H Rozenbaum
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, Netherlands
    BMJ 340:c2509. 2010
  10. pmc Contributing factors to influenza vaccine uptake in general hospitals: an explorative management questionnaire study from the Netherlands
    Josien Riphagen-Dalhuisen
    Department of Pharmacy, Division of Pharmacoepidemiology and Pharmacoeconomics, University of Groningen, Antonius Deusinglaan 1, Groningen, The Netherlands
    BMC Public Health 12:1101. 2012

Detail Information

Publications27

  1. pmc Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma: bidirectional crossover study using the general practice research database
    Eelko Hak
    Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University Groningen, Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    Drug Saf 36:1097-104. 2013
    ..Recent studies have reported an association between maternal use of gastric acid-suppressive drugs during pregnancy and asthma in the offspring, but the association could have been confounded by unmeasured risk factors...
  2. pmc Prevalence and predictors of over-the-counter medication use among pregnant women: a cross-sectional study in the Netherlands
    Gwenny Mpj Verstappen
    University Center for Pharmacy, Pharmacoepidemiology and Pharmacoeconomics, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    BMC Public Health 13:185. 2013
    ..To successfully counsel the patient it is important to know if the patient is at risk. In this study possible predictors for OTC-medication use were identified and a model was designed to predict OTC-medication use during pregnancy...
  3. doi request reprint Association of childhood attention-deficit/hyperactivity disorder with atopic diseases and skin infections? A matched case-control study using the General Practice Research Database
    Eelko Hak
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Ann Allergy Asthma Immunol 111:102-106.e2. 2013
    ..Data to support the hypothesis of a relationship between attention-deficit/hyperactivity disorder (ADHD) and allergies are conflicting...
  4. doi request reprint Association of infant pneumococcal vaccination with pneumococcal pneumonia among mothers: a nested case-control study using the GPRD
    Eelko Hak
    Unit of Pharmaco epidemiology and Pharmaco economics, Department of Pharmacy, University Groningen, The Netherlands
    Vaccine 31:1590-6. 2013
    ..Though there is a chance of bias inherent to observational studies, the study findings support close monitoring of adult pneumococcal disease and potential role of adult vaccination needs to be explored...
  5. pmc Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial
    Janna M Munster
    University of Groningen, University Centre for Pharmacy, Pharmacoepidemiology and Pharmacoeconomics, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    BMC Womens Health 10:32. 2010
    ..We designed a trial to assess the (cost-)effectiveness of a screening program for Q fever in pregnant women living in risks areas in The Netherlands...
  6. doi request reprint Assessing the effect of a guideline change on drug use prevalence by including the birth cohort dimension: the case of benzodiazepines
    Maarten J Bijlsma
    Unit Pharmacoepidemiology and Pharmacoeconomics PE2, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Pharmacoepidemiol Drug Saf 22:933-41. 2013
    ..The aim of this study was to investigate whether including the birth cohort dimension in time series analysis leads to a more accurate estimation of the (long-term) effect of a guideline change on the trend of benzodiazepine use...
  7. ncbi request reprint Cost-effectiveness of statins for primary prevention in patients newly diagnosed with type 2 diabetes in the Netherlands
    Folgerdiena M de Vries
    Department of Pharmacy, Unit of PharmacoEpidemiology and PharmacoEconomics PE2, University of Groningen, Groningen, The Netherlands Electronic address
    Value Health 17:223-30. 2014
    ..Statins are lipid-lowering drugs that reduce the risk of cardiovascular events in patients with diabetes...
  8. pmc Planning and process evaluation of a multi-faceted influenza vaccination implementation strategy for health care workers in acute health care settings
    Josien Riphagen-Dalhuisen
    Department of Pharmacoepidemiology and Pharmacoeconomics, University Centre of Pharmacy, University of Groningen, A Deusinglaan 1, P O Box XB45, Groningen 9713 AV, The Netherlands
    BMC Infect Dis 13:235. 2013
    ..This study explores the use of intervention strategies and methods to improve influenza vaccination rates among HCWs in an acute care setting...
  9. ncbi request reprint Cost effectiveness of pneumococcal vaccination among Dutch infants: economic analysis of the seven valent pneumococcal conjugated vaccine and forecast for the 10 valent and 13 valent vaccines
    Mark H Rozenbaum
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, Netherlands
    BMJ 340:c2509. 2010
    ....
  10. pmc Contributing factors to influenza vaccine uptake in general hospitals: an explorative management questionnaire study from the Netherlands
    Josien Riphagen-Dalhuisen
    Department of Pharmacy, Division of Pharmacoepidemiology and Pharmacoeconomics, University of Groningen, Antonius Deusinglaan 1, Groningen, The Netherlands
    BMC Public Health 12:1101. 2012
    ..As there is a lack of research about management factors we assessed factors reported by administrators of general hospitals that are associated with the influenza vaccine uptake among health care workers...
  11. ncbi request reprint Angiotensin-converting enzyme inhibitor treatment and the development of urinary tract infections: a prescription sequence symmetry analysis
    Koen B Pouwels
    Unit of PharmacoEpidemiology and PharmacoEconomics PE, Department of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    Drug Saf 36:1079-86. 2013
    ..Since bacterial clearance from the urinary tract is dependent on urine output, it was hypothesized that ACEi may also increase the risk of urinary tract infections (UTIs)...
  12. doi request reprint Observed differences in invasive pneumococcal disease epidemiology after routine infant vaccination
    Mark H Rozenbaum
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Expert Rev Vaccines 10:187-99. 2011
    ..We conclude that the health and economic impact should be addressed in light of the country specific pneumoccocal disease epidemiology to support decisions on immunization programs...
  13. doi request reprint Cost-effectiveness of vaccination of the elderly against herpes zoster in The Netherlands
    Pieter T de Boer
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Netherlands
    Vaccine 31:1276-83. 2013
    ..A large randomized clinical trial, labelled the Shingles Prevention study (SPS), demonstrated that a live attenuated VZV vaccine can reduce the incidence of HZ and PHN...
  14. pmc Using spatial analysis to predict health care use at the local level: a case study of type 2 diabetes medication use and its association with demographic change and socioeconomic status
    Aletta Dijkstra
    Unit of PharmacoEpidemiology and PharmacoEconomics PE2, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    PLoS ONE 8:e72730. 2013
    ..The findings demonstrate the added value of spatial analysis in predicting health care use at local level. ..
  15. pmc Comparatively low attendance during Human Papillomavirus catch-up vaccination among teenage girls in the Netherlands: Insights from a behavioral survey among parents
    Giedre Gefenaite
    Department of Pharmacy, PharmacoEpidemiology and PharmacoEconomics PE2, University of Groningen, Groningen, The Netherlands
    BMC Public Health 12:498. 2012
    ..The Dutch Human Papillomavirus (HPV) catch-up vaccination program in 2009 appeared less successful than expected. We aimed to identify the most important determinants of refusing the vaccination...
  16. doi request reprint Results of a cohort model analysis of the cost-effectiveness of routine immunization with 13-valent pneumococcal conjugate vaccine of those aged > or =65 years in the Netherlands
    Mark H Rozenbaum
    Department of Pharmacy, University of Groningen, The Netherlands
    Clin Ther 32:1517-32. 2010
    ..Community-acquired pneumonia and invasive pneumococcal disease are common among older people (ie, those aged > or =65 years). A new 13-valent pneumococcal conjugate vaccine (PCV-13) is under study in the Netherlands...
  17. pmc Cost-effectiveness of rotavirus vaccination in the Netherlands; the results of a consensus model
    Mark H Rozenbaum
    Unit of PharmacoEpidemiology and PharmacoEconomics PE2, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    BMC Public Health 11:462. 2011
    ..We aimed to investigate which factors had a major impact on cost-effectiveness and were primarily responsible for the large differences in previously estimated cost-effectiveness ratios...
  18. pmc Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination
    Giedre Gefenaite
    Department of Pharmacy, Unit of PharmacoEpidemiology and PharmacoEconomics PE2, University of Groningen, Groningen, The Netherlands
    PLoS ONE 8:e66125. 2013
    ..Because of variability in published A(H1N1)pdm09 influenza vaccine effectiveness estimates, we conducted a study in the adults belonging to the risk groups to assess the A(H1N1)pdm09 MF59-adjuvanted influenza vaccine effectiveness...
  19. doi request reprint Predictors of seasonal influenza vaccination among healthcare workers in hospitals: a descriptive meta-analysis
    Josien Riphagen-Dalhuisen
    University of Groningen, Department of Pharmacy, Division of Pharmacoepidemiology and Pharmacoeconomics, PO Box XB45, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    Occup Environ Med 69:230-5. 2012
    ..The objective of this meta-analysis was to determine the most important predictors of seasonal influenza vaccine acceptance among HCWs in hospitals...
  20. doi request reprint A systematic review of the application of spatial analysis in pharmacoepidemiologic research
    Aletta Dijkstra
    Unit of PharmacoEpidemiology and PharmacoEconomics PE 2, Department of Pharmacy, University of Groningen, The Netherlands
    Ann Epidemiol 23:504-14. 2013
    ....
  21. pmc How to develop a program to increase influenza vaccine uptake among workers in health care settings?
    Ingrid Looijmans-Van den Akker
    University of Groningen, Department of Pharmacy, Pharmacoepidemiology and Pharmacoeconomy, A, Deusinglaan 1, 9713 AV, Groningen, The Netherlands
    Implement Sci 6:47. 2011
    ..Here, we report in detail the process of the development of the implementation program to enable researchers and practitioners to develop intervention programs tailored to their setting...
  22. ncbi request reprint [Influenza vaccination of hospital healthcare staff from the perspective of the employer: a positive balance]
    Eelko Hak
    Rijksuniversiteit Groningen, Groningen Research Institute for Pharmacy GRIP, unit Farmaco epidemiologie and Farmaco economie FE2, Groningen, The Netherlands
    Ned Tijdschr Geneeskd 154:A1188. 2010
    ..To assess the annual productivity loss among hospital healthcare workers attributable to influenza and to estimate the costs and economic benefits of a vaccination programme from the perspective of the the employer...
  23. doi request reprint Seasonal influenza vaccine effectiveness against influenza in 2012-2013: a hospital-based case-control study in Lithuania
    Giedre Gefenaite
    Department of Pharmacy, Unit of PharmacoEpidemiology and PharmacoEconomics PE2, University of Groningen, A Deusinglaan 1, P O Box XB45, 9713AV Groningen, The Netherlands Department of Epidemiology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, P O Box 30 001, FA40, 9700RB Groningen, The Netherlands Electronic address
    Vaccine 32:857-63. 2014
    ....
  24. doi request reprint Inclusion of the birth cohort dimension improved description and explanation of trends in statin use
    Maarten J Bijlsma
    Unit PharmacoEpidemiology and PharmacoEconomics PE 2, Department of Pharmacy, University of Groningen, A Deusinglaan 1, Groningen 9713 AV, The Netherlands
    J Clin Epidemiol 65:1052-60. 2012
    ..We investigated the effect of including the birth cohort dimension in trend studies of prescription drug use by studying prevalence of statin use among adults...
  25. doi request reprint Primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis
    Folgerdiena M de Vries
    Unit of PharmacoEpidemiology PharmacoEconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Drugs 72:2365-73. 2012
    ..Individual trials have shown varying data on the efficacy of treatment with lipid-lowering statin therapy in the primary prevention of such events in diabetes...
  26. pmc Effect of pravastatin and fosinopril on recurrent urinary tract infections
    Koen B Pouwels
    Unit of Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    J Antimicrob Chemother 68:708-14. 2013
    ..Animal experiments and in vitro studies indicate that statins might prevent recurrent UTIs. We assessed the effects of pravastatin on UTI antibiotic prescribing among adults...
  27. doi request reprint Huge impact of assumptions on indirect effects on the cost-effectiveness of routine infant vaccination with 7-valent conjugate vaccine (Prevnar)
    Mark H Rozenbaum
    Unit of PharmacoEpidemiology and PharmacoEconomics PE 2, Department of Pharmacy, University of Groningen, Groningen, The Netherlands
    Vaccine 28:2367-9. 2010
    ....