Mijna Hadders-Algra

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. doi request reprint Prenatal and early postnatal supplementation with long-chain polyunsaturated fatty acids: neurodevelopmental considerations
    Mijna Hadders-Algra
    Department of Pediatrics, Developmental Neurology, University Medical Center, Groningen, Netherlands
    Am J Clin Nutr 94:1874S-1879S. 2011
  2. ncbi request reprint Discussion on the clinical relevance of activity-dependent plasticity after an insult to the developing brain
    Mijna Hadders-Algra
    Department of Neurology, Institute of Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 31:1213-9. 2007
  3. ncbi request reprint Putative neural substrate of normal and abnormal general movements
    Mijna Hadders-Algra
    Department of Neurology, Institute of Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 31:1181-90. 2007
  4. doi request reprint Challenges and limitations in early intervention
    Mijna Hadders-Algra
    Department of Pediatrics, Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:52-5. 2011
  5. pmc Effect of long-chain polyunsaturated fatty acid supplementation on neurodevelopmental outcome in full-term infants
    Mijna Hadders-Algra
    Department of Pediatrics Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Nutrients 2:790-804. 2010
  6. ncbi request reprint Prenatal and early postnatal fatty acid status and neurodevelopmental outcome
    Mijna Hadders-Algra
    Department of Neurology Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    J Perinat Med 35:S28-34. 2007
  7. ncbi request reprint Effect of seat surface inclination on postural control during reaching in preterm children with cerebral palsy
    Mijna Hadders-Algra
    Department of Developmental Neurology, University Medical Centre Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands
    Phys Ther 87:861-71. 2007
  8. doi request reprint The assessment of minor neurological dysfunction in infancy using the Touwen Infant Neurological Examination: strengths and limitations
    Mijna Hadders-Algra
    Department of Paediatrics and Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:87-92. 2010
  9. doi request reprint Prenatal long-chain polyunsaturated fatty acid status: the importance of a balanced intake of docosahexaenoic acid and arachidonic acid
    Mijna Hadders-Algra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    J Perinat Med 36:101-9. 2008
  10. doi request reprint Reduced variability in motor behaviour: an indicator of impaired cerebral connectivity?
    Mijna Hadders-Algra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Early Hum Dev 84:787-9. 2008

Collaborators

Detail Information

Publications94

  1. doi request reprint Prenatal and early postnatal supplementation with long-chain polyunsaturated fatty acids: neurodevelopmental considerations
    Mijna Hadders-Algra
    Department of Pediatrics, Developmental Neurology, University Medical Center, Groningen, Netherlands
    Am J Clin Nutr 94:1874S-1879S. 2011
    ....
  2. ncbi request reprint Discussion on the clinical relevance of activity-dependent plasticity after an insult to the developing brain
    Mijna Hadders-Algra
    Department of Neurology, Institute of Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 31:1213-9. 2007
  3. ncbi request reprint Putative neural substrate of normal and abnormal general movements
    Mijna Hadders-Algra
    Department of Neurology, Institute of Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 31:1181-90. 2007
    ....
  4. doi request reprint Challenges and limitations in early intervention
    Mijna Hadders-Algra
    Department of Pediatrics, Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:52-5. 2011
    ....
  5. pmc Effect of long-chain polyunsaturated fatty acid supplementation on neurodevelopmental outcome in full-term infants
    Mijna Hadders-Algra
    Department of Pediatrics Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Nutrients 2:790-804. 2010
    ..It is conceivable that effects of LCPUFA supplementation first emerge or re-emerge at school age when more complex neural functions are expressed...
  6. ncbi request reprint Prenatal and early postnatal fatty acid status and neurodevelopmental outcome
    Mijna Hadders-Algra
    Department of Neurology Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    J Perinat Med 35:S28-34. 2007
    ....
  7. ncbi request reprint Effect of seat surface inclination on postural control during reaching in preterm children with cerebral palsy
    Mijna Hadders-Algra
    Department of Developmental Neurology, University Medical Centre Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands
    Phys Ther 87:861-71. 2007
    ..Because it is debatable whether seat surface inclination improves motor function in children with cerebral palsy (CP), the effect of seat surface tilting on postural control and quality of reaching was studied...
  8. doi request reprint The assessment of minor neurological dysfunction in infancy using the Touwen Infant Neurological Examination: strengths and limitations
    Mijna Hadders-Algra
    Department of Paediatrics and Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:87-92. 2010
    ..This study aimed to evaluate the inter-assessor reliability of the assessment of MND with the Touwen Infant Neurological Examination (TINE) and the construct and predictive validity of MND in infancy...
  9. doi request reprint Prenatal long-chain polyunsaturated fatty acid status: the importance of a balanced intake of docosahexaenoic acid and arachidonic acid
    Mijna Hadders-Algra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    J Perinat Med 36:101-9. 2008
    ..Caution is warranted for an unbalanced high DHA intake during the first two trimesters of pregnancy, i.e., DHA without additional AA supplementation...
  10. doi request reprint Reduced variability in motor behaviour: an indicator of impaired cerebral connectivity?
    Mijna Hadders-Algra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Early Hum Dev 84:787-9. 2008
    ..e., in a reduction of movement complexity and variation, whereas reduction in long-distance cortical connectivity, as described in children with ASD, is associated with reduced variability, in which movement complexity may be conserved...
  11. doi request reprint Quality of general movements and psychiatric morbidity at 9 to 12 years
    Mijna Hadders-Algra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Developmental Neurology, Groningen, The Netherlands
    Early Hum Dev 85:1-6. 2009
    ..The quality of GMs may predict neurological outcome, but little is known about relationships between GM-quality and behavioral problems, including those resulting in overt psychiatric morbidity...
  12. doi request reprint Variation and variability: key words in human motor development
    Mijna Hadders-Algra
    Department of Pediatrics Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Phys Ther 90:1823-37. 2010
    ..The possible applications of variation and variability in diagnostics in children with or at risk for a developmental motor disorder are discussed...
  13. ncbi request reprint The neuromotor examination of the preschool child and its prognostic significance
    Mijna Hadders-Algra
    Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Ment Retard Dev Disabil Res Rev 11:180-8. 2005
    ..This means that further research on applicability and validity of preschool neuromotor assessment is urgently needed...
  14. ncbi request reprint Postural control during reaching in preterm children with cerebral palsy
    Jolanda C van der Heide
    Department of Neurology, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 46:253-66. 2004
    ..Postural dysfunctions were correlated to some extent with the degree of disability in everyday activities as assessed by the Pediatric Evaluation of Disability Inventory...
  15. doi request reprint Development of proximal arm muscle control during reaching in young infants: from variation to selection
    Hanneke Bakker
    Department Paediatrics Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Infant Behav Dev 33:30-8. 2010
    ..BB as prime mover at 6 months was related to a larger transport MU. Conclusion: Between 4 and 6 months BB prime mover dominance emerges which is related to relatively efficient reaching characteristics...
  16. ncbi request reprint Lower fetal status of docosahexaenoic acid, arachidonic acid and essential fatty acids is associated with less favorable neonatal neurological condition
    D A Janneke Dijck-Brouwer
    Pathology and Laboratory Medicine, University Hospital Groningen DAJD B, FAJM, Hanzeplein 1, 9714 GZ Gronigen, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 72:21-8. 2005
    ..2% of the NOS variance. Early postnatal neurological condition seems negatively influenced by lower fetal DHA, AA and EFA status. C18 trans fatty acids and 18:2omega6 may exert negative effects by impairment of LCP status...
  17. doi request reprint Supplementation of DHA but not DHA with arachidonic acid during pregnancy and lactation influences general movement quality in 12-week-old term infants
    Saskia A van Goor
    Laboratory Medicine, University Medical Center Groningen, Internal postal code EA22, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Br J Nutr 103:235-42. 2010
    ..008) and 34 % in the DHA+AA group (P = 0.015). We conclude that general movement quality at 12 weeks is sensitive to the maternal dietary DHA/AA balance...
  18. doi request reprint Reliability and concurrent validity of the Infant Motor Profile
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 55:539-45. 2013
    ..The aim of this study was to assess interobserver reliability and concurrent validity of the IMP with the Alberta Infant Motor Scale (AIMS) and an age-specific neurological examination...
  19. doi request reprint Construct validity of the Infant Motor Profile: relation with prenatal, perinatal, and neonatal risk factors
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:e209-15. 2010
    ....
  20. doi request reprint The Groningen assisted reproductive technologies cohort study: developmental status and behavior at 2 years
    Marjolein Jongbloed-Pereboom
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Fertil Steril 95:2283-9. 2011
    ..To evaluate whether children's cognitive and psychomotor development and behavior at 2 years are affected by ovarian hyperstimulation and the IVF laboratory procedures or subfertility...
  21. doi request reprint The Groningen LCPUFA study: no effect of postnatal long-chain polyunsaturated fatty acids in healthy term infants on neurological condition at 9 years
    Corina de Jong
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Centre Groningen, Groningen, The Netherlands
    Br J Nutr 104:566-72. 2010
    ..The study confirmed that breast-fed infants have a slightly better neurodevelopmental outcome than formula-fed infants...
  22. ncbi request reprint Neurologic condition of healthy term infants at 18 months: positive association with venous umbilical DHA status and negative association with umbilical trans-fatty acids
    Hylco Bouwstra
    Department of Neurology, University of Groningen, Perinatal Nutrition and Development Unit, University Medical Center Groningen, 9700 RB, Groningen, The Netherlands
    Pediatr Res 60:334-9. 2006
    ..In conclusion, neonates with a relatively low DHA status and those with high trans-fatty acid levels have a less favorable neurologic condition at 18 mo...
  23. ncbi request reprint Postural adjustments and reaching in 4- and 6-month-old infants: an EMG and kinematical study
    Victorine B de Graaf-Peters
    Department of Neurology Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Exp Brain Res 181:647-56. 2007
    ..Nevertheless, already from 4 months onwards a better postural control is associated with a larger success and a better quality of reaching...
  24. doi request reprint Predictive value of definitely abnormal general movements in the general population
    Hylco Bouwstra
    Beatrix Children s Hospital Developmental Neurology, University Medical Centre Groningen, 9713 GZ Groningen, The Netherlands
    Dev Med Child Neurol 52:456-61. 2010
    ..This study aimed to assess predictive values of definitely abnormal general movements at 3 months for serious neurodevelopmental impairment in a representative sample of the general population...
  25. doi request reprint Development of a quantitative tool to assess the content of physical therapy for infants
    Cornill H Blauw-Hospers
    Department of Pediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Pediatr Phys Ther 22:189-97. 2010
    ..The study aim was to describe and quantify physical therapy interventions for infants at high risk for developmental disorders...
  26. ncbi request reprint Kinematic characteristics of reaching movements in preterm children with cerebral palsy
    Jolanda C van der Heide
    Department of Neurology, University of Groningen, 9713 GZ Groningen, The Netherlands
    Pediatr Res 57:883-9. 2005
    ..The last indicates that movements of the dominant arm in children with spastic hemiplegia and Bi-CP deserve clinical attention...
  27. doi request reprint Does physiotherapeutic intervention affect motor outcome in high-risk infants? An approach combining a randomized controlled trial and process evaluation
    Tjitske Hielkema
    Division of Developmental Neurology, Department of Paediatrics, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:e8-15. 2011
    ....
  28. doi request reprint The influence of supplemental docosahexaenoic and arachidonic acids during pregnancy and lactation on neurodevelopment at eighteen months
    Saskia A van Goor
    Laboratory Medicine, University Medical Center Groningen, Groningen, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 84:139-46. 2011
    ..We conclude that relatively short-term maternal DHA or DHA+AA supplementation does not influence neurodevelopment at toddler age, although some parameters of brain development are related to perinatal DHA and AA status...
  29. doi request reprint Infant Motor Profile and cerebral palsy: promising associations
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:40-5. 2011
    ..Furthermore, we evaluated the predictive ability of IMP scores throughout infancy for CP...
  30. ncbi request reprint Relationship between umbilical cord essential fatty acid content and the quality of general movements of healthy term infants at 3 months
    Hylco Bouwstra
    Department of Neurology, University Hospital Groningen, 9700 RB, Groningen, The Netherlands
    Pediatr Res 59:717-22. 2006
    ..Multivariate analyses confirmed these findings. We conclude that mildly abnormal GMs are associated with a less favorable EFA status in the umbilical artery...
  31. ncbi request reprint General movements: A window for early identification of children at high risk for developmental disorders
    Mijna Hadders-Algra
    Department of Neurology Developmental Neurology, University of Groningen, Groningen, The Netherlands
    J Pediatr 145:S12-8. 2004
    ..This implies that definitely abnormal GMs at fidgety age are an indication for early physiotherapeutic intervention...
  32. doi request reprint Assessment of specific characteristics of abnormal general movements: does it enhance the prediction of cerebral palsy?
    Elisa G Hamer
    Division of Developmental Neurology, Department of Paediatrics, University Medical Centre Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:751-6. 2011
    ..We aimed to determine whether specific movement characteristics can improve the predictive power of definitely abnormal general movements...
  33. ncbi request reprint Kinematic characteristics of postural control during reaching in preterm children with cerebral palsy
    Jolanda C van der Heide
    Department of Neurology, University Hospital Groningen, The Netherlands
    Pediatr Res 58:586-93. 2005
    ..This suggests that physiotherapeutic guidance of children with CP should focus rather on the latter postural parameters than on the different sitting posture of pelvis and trunk...
  34. doi request reprint The Infant Motor Profile: a standardized and qualitative method to assess motor behaviour in infancy
    Kirsten R Heineman
    Department of Neurology, Institute of Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 50:275-82. 2008
    ..005). This means that the IMP may be a promising tool to evaluate neurological integrity during infancy, a suggestion that needs confirmation by means of assessment of larger groups of infants with heterogeneous neurological conditions...
  35. doi request reprint Mental, psychomotor, neurologic, and behavioral outcomes of 2-year-old children born after preimplantation genetic screening: follow-up of a randomized controlled trial
    Karin J Middelburg
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center, Groningen, The Netherlands
    Fertil Steril 96:165-9. 2011
    ..To evaluate the effect of preimplantation genetic screening (PGS) on neurodevelopmental outcomes in children...
  36. doi request reprint Effects of long-chain polyunsaturated fatty acid supplementation of infant formula on cognition and behaviour at 9 years of age
    Corina de Jong
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 54:1102-8. 2012
    ..Special attention was paid to the potentially modifying effect of maternal smoking during pregnancy...
  37. ncbi request reprint Test-retest, inter-assessor and intra-assessor reliability of the modified Touwen examination
    Lieke H J Peters
    Department of Neurology Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Eur J Paediatr Neurol 12:328-33. 2008
    ..Whether reliability is similarly good in populations of children with minor developmental disorders has to be determined...
  38. pmc Development of postural adjustments during reaching in typically developing infants from 4 to 18 months
    Lieke C van Balen
    Department of Paediatrics, Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Exp Brain Res 220:109-19. 2012
    ..Already from 4 months onwards, infants are-within the variation-sometimes able to select muscle recruitment strategies that are optimal to the task at hand...
  39. pmc Development of postural control during the first 18 months of life
    Mijna Hadders-Algra
    Department of Neurology, Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neural Plast 12:99-108; discussion 263-72. 2005
    ..The major transition occurs at 6 months, when infants move from the phase of non-adaptive, primary variability to the phase of adaptive, secondary variability...
  40. doi request reprint Human milk arachidonic acid and docosahexaenoic acid contents increase following supplementation during pregnancy and lactation
    Saskia A van Goor
    Pathology and Laboratory Medicine, UMCG, University Medical Center Groningen, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 80:65-9. 2009
    ..Maternal diet influences milk DHA, whereas milk AA seems rather constant. We investigated milk AA, DHA and DHA/AA after supplementation of AA plus DHA, or DHA alone during pregnancy and lactation...
  41. ncbi request reprint Long-chain polyunsaturated fatty acids in maternal and infant nutrition
    Frits A J Muskiet
    Pathology and Laboratory Medicine, University Medical Center Groningen, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 75:135-44. 2006
    ..Subtle signs of dysbalanced maternal glucose homeostasis may be important and observations from current Western societies may not provide us with an adequate basis for dietary recommendations...
  42. ncbi request reprint Development of postural control in typically developing children and children with cerebral palsy: possibilities for intervention?
    Victorine B de Graaf-Peters
    Department Neurology and Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 31:1191-200. 2007
    ....
  43. ncbi request reprint Long-chain polyunsaturated fatty acids have a positive effect on the quality of general movements of healthy term infants
    Hylco Bouwstra
    Department of Neurology, University of Groningen, Groningen, The Netherlands
    Am J Clin Nutr 78:313-8. 2003
    ..Whether long-chain polyunsaturated fatty acids (LCPs) play a role in the development of the young nervous system in term infants is debated...
  44. doi request reprint Ovarian hyperstimulation and the in vitro fertilization procedure do not influence early neuromotor development; a history of subfertility does
    Karin J Middelburg
    Division of Developmental Neurology, Department of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Fertil Steril 93:544-53. 2010
    ..To evaluate specific effects of ovarian hyperstimulation, the in vitro procedure, and a history of subfertility on neuromotor development at 3 months of age...
  45. ncbi request reprint Development of postural adjustments during reaching in sitting children
    Jolanda C van der Heide
    Department of Neurology, University of Groningen, Groningen, The Netherlands
    Exp Brain Res 151:32-45. 2003
    ..In addition, the study suggested that, in terms of postural control, the forward-tilted position is the most efficient one...
  46. ncbi request reprint Quality of general movements and the development of minor neurological dysfunction at toddler and school age
    Mijna Hadders-Algra
    Department of Neurology, University of Groningen, The Netherlands
    Clin Rehabil 18:287-99. 2004
    ..To evaluate the reliability of assessing infants' general movements (GMs) using a new classification and its validity in predicting complex minor neurological dysfunction (MND) at toddler and at school age...
  47. doi request reprint Minor neurological dysfunction and IQ in 9-year-old children born at term
    Hedwig K Kikkert
    Department of Paediatrics Developmental Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 53:e16-25. 2011
    ..The aim of this study was to examine the relationship between the severity and type of minor neurological dysfunction (MND) and IQ in 9-year-old children born at term...
  48. doi request reprint Differences between the family-centered "COPCA" program and traditional infant physical therapy based on neurodevelopmental treatment principles
    Tineke Dirks
    Department of Pediatrics Developmental Neurology, Beatrix Children s Hospital, University Medical Center Groningen, Groningen, The Netherlands
    Phys Ther 91:1303-22. 2011
    ..The COPCA coach uses principles of coaching to encourage the family's own capacities for solving problems of daily care and incorporating variation, along with trial and error in daily activities...
  49. ncbi request reprint General movements in early infancy predict neuromotor development at 9 to 12 years of age
    Sabina E Groen
    Centre of Rehabilitation, University Medical Center, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 47:731-8. 2005
    ..1, p=0.01) and fine manipulative disability (Fisher, p<0.05) at 9 to 12 years. This finding supports the notion that the quality of GMs may provide information on the integrity of complex supraspinal circuitries...
  50. pmc Increased time to pregnancy is associated with suboptimal neurological condition of 2-year-olds
    Jorien Seggers
    Department of Paediatrics, Division of Developmental Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Arch Dis Child Fetal Neonatal Ed 98:F434-6. 2013
    ..To evaluate whether time to pregnancy (TTP) is associated with neurological condition of 2-year-old children born to subfertile parents...
  51. doi request reprint Use and functioning of the affected limb in children with unilateral congenital below-elbow deficiency during infancy and preschool age: a longitudinal observational multiple case study
    Mijna Hadders-Algra
    Dept of Paediatrics Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Early Hum Dev 89:49-54. 2013
    ..Little is known on the performance of daily activities in very young children with UCBED, usage of their affected arm with or without prosthesis during play, and neurological condition...
  52. doi request reprint Movement variation in infants born following IVF/ICSI with and without ovarian hyperstimulation
    Pamela Schendelaar
    Dept of Paediatrics, Div of Developmental Neurology CA 85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Early Hum Dev 89:507-13. 2013
    ..It includes the evaluation of movement variation (i.e. movement repertoire size), a parameter reflecting the integrity of cortical connectivity...
  53. doi request reprint Dysmorphic features in 2-year-old IVF/ICSI offspring
    Jorien Seggers
    Dept Pediatrics, Div Developmental Neurology, University Medical Center Groningen, The Netherlands
    Early Hum Dev 88:823-9. 2012
    ..This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of dysmorphic features...
  54. doi request reprint Handwriting, visuomotor integration, and neurological condition at school age
    Jessika F van Hoorn
    Center for Rehabilitation, University Medical Center Groningen, University of Groningen, Netherlands
    Dev Med Child Neurol 52:941-7. 2010
    ..the study investigated the relationships between handwriting, visuomotor integration, and neurological condition. We paid particular attention to the presence of minor neurological dysfunction (MND)...
  55. pmc Postural muscle dyscoordination in children with cerebral palsy
    Jolanda C van der Heide
    Department of Neurology, University of Groningen, The Netherlands
    Neural Plast 12:197-203; discussion 263-72. 2005
    ..This might imply that both stereotypies might be regarded as functional strategies to compensate for the dysfunctional capacity to modulate subtly postural activity...
  56. doi request reprint Pediatric physical therapy in infancy: from nightmare to dream? A two-arm randomized trial
    Cornill H Blauw-Hospers
    Department of Pediatrics Developmental Neurology, Beatrix Children s Hospital, University Medical Center Groningen, Groningen, The Netherlands
    Phys Ther 91:1323-38. 2011
    ....
  57. doi request reprint Evaluation of neuromotor function in infancy-A systematic review of available methods
    Kirsten R Heineman
    Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    J Dev Behav Pediatr 29:315-23. 2008
    ..The assessments may also be used to monitor intervention. The present article will review the psychometric properties of methods to assess neuromotor function in infancy...
  58. doi request reprint GMFM in infancy: age-specific limitations and adaptations
    Tjitske Hielkema
    Departments of Paediatrics Developmental Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Pediatr Phys Ther 25:168-76; discussion 177. 2013
    ..To evaluate longitudinal applicability of the gross motor function measure (GMFM) in infants younger than 2 years...
  59. pmc LEARN 2 MOVE 0-2 years: effects of a new intervention program in infants at very high risk for cerebral palsy; a randomized controlled trial
    Tjitske Hielkema
    Beatrix Children s Hospital Division of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    BMC Pediatr 10:76. 2010
    ..The objective is to evaluate the effects of both intervention programs on motor, cognitive and daily functioning of the child and the family and to get insight in the working elements of early intervention methods...
  60. doi request reprint Limited motor performance and minor neurological dysfunction at school age
    Lieke H J Peters
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, University of Groningen, The Netherlands
    Acta Paediatr 100:271-8. 2011
    ..To investigate the relationship between motor performance and minor neurological dysfunction (MND) at school age...
  61. doi request reprint The Groningen LCPUFA study: No effect of short-term postnatal long-chain polyunsaturated fatty acids in healthy term infants on cardiovascular and anthropometric development at 9 years
    Corina de Jong
    Department of Paediatrics, University Medical Center Groningen, Groningen 9700RB, The Netherlands
    Pediatr Res 70:411-6. 2011
    ..In conclusion, the study suggests that short-term LCPUFA supplementation does not influence cardiovascular and anthropometric development at 9 y...
  62. ncbi request reprint Does surgical management of the hand in children with spastic unilateral cerebral palsy affect functional outcome?
    Judith C van Munster
    Centre for Rehabilitation, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 49:385-9. 2007
    ..Future research should address the question: does surgery improve hand function and, if so, is this due solely to a better hand position or does change in muscle coordination play an additional role?..
  63. doi request reprint Maternal anxiety is related to infant neurological condition, paternal anxiety is not
    Hedwig K Kikkert
    Dept of Paediatrics, Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Early Hum Dev 86:171-7. 2010
    ..Parental anxiety and stress may have consequences for infant neurological development...
  64. doi request reprint Age at first prosthetic fitting and later functional outcome in children and young adults with unilateral congenital below-elbow deficiency: a cross-sectional study
    Karin Huizing
    Department of Rehabilitation, University Medical Center Groningen, Groningen, The Netherlands
    Prosthet Orthot Int 34:166-74. 2010
    ..The video assessments showed impaired movement adaptation to some tasks in six subjects. In conclusion, early prosthetic fitting seems to have a limited impact on prosthesis use during later stages of life...
  65. doi request reprint Neurological condition of infants born after in vitro fertilization with preimplantation genetic screening
    Karin J Middelburg
    Departments of Pediatrics, University Medical Center Groningen, The Netherlands
    Pediatr Res 67:430-4. 2010
    ..The small sample size precludes the conclusion that PGS is not associated with less favorable neurologic outcome. Safety of new assisted reproductive techniques should be evaluated before large-scale implementation...
  66. ncbi request reprint Specific postural support promotes variation in motor behaviour of infants with minor neurological dysfunction
    Victorine B de Graaf-Peters
    Department of Neurology, Developmental Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 48:966-72. 2006
    ..001). Our results demonstrate that specific postural support promotes variation in motor behaviour of young infants. This is particularly true for infants with MND...
  67. pmc Developmental coordination disorder: is clumsy motor behavior caused by a lesion of the brain at early age?
    Mijna Hadders-Algra
    Department of Neurology Developmental Neurology, University of Groningen, Groningen, The Netherlands
    Neural Plast 10:39-50. 2003
    ..In line with this idea is the finding that complex MND shows a strong correlation with attention and learning problems...
  68. ncbi request reprint Impaired maternal glucose homeostasis during pregnancy is associated with low status of long-chain polyunsaturated fatty acids (LCP) and essential fatty acids (EFA) in the fetus
    D A Janneke Dijck-Brouwer
    Pathology and Laboratory Medicine, Room Y1 165, Groningen University Hospital, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 73:85-7. 2005
    ..We conclude that children born to mothers with poor glucose homeostasis have lower EFA and LCP status, which is consistent with a 'relative deficiency' deriving from augmented de novo fatty acid synthesis from the abundant glucose...
  69. ncbi request reprint The role of long-chain polyunsaturated fatty acids (LCPUFA) in growth and development
    Mijna Hadders-Algra
    Dept of Neurology Developmental Neurology, University Hospital Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Adv Exp Med Biol 569:80-94. 2005
    ..Thus it is possible that LCPUFA might have a long lasting beneficial effect on neurodevelopmental outcome at school-age and beyond. This hypothesis urgently needs testing...
  70. doi request reprint Risk factors for emergence and progression of scoliosis in children with severe cerebral palsy: a systematic review
    Marianne J B Loeters
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, Groningen, The Netherlands
    Dev Med Child Neurol 52:605-11. 2010
    ..This systematic review aims to the assess the risk factors associated with the emergence and progression of scoliosis in children with CP functioning at level IV or V of the Gross Motor Function Classification System (GMFCS)...
  71. ncbi request reprint A systematic review of the effects of early intervention on motor development
    Cornill H Blauw-Hospers
    Department of Neurology Developmental Neurology, University of Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 47:421-32. 2005
    ..After term age, intervention by means of specific or general developmental programmes has a positive effect on motor development...
  72. ncbi request reprint Two distinct forms of minor neurological dysfunction: perspectives emerging from a review of data of the Groningen Perinatal Project
    Mijna Hadders-Algra
    Department of Neurology, University of Groningen, The Netherlands
    Dev Med Child Neurol 44:561-71. 2002
  73. doi request reprint Prevalence of abnormal general movements in three-month-old infants
    Hylco Bouwstra
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Early Hum Dev 85:399-403. 2009
    ..The quality of general movements (GMs) is a sensitive tool to measure neurodevelopmental condition in early infancy. No information is available on prevalence rates of abnormal GMs in the general population...
  74. ncbi request reprint Development of postural adjustments in sitting position during the first half year of life
    Asa Hedberg
    Neuropaediatric Research Unit, Q2 07, Karolinska Institutet, Department of Woman and Child Health, Astrid Lindgrens Children s Hospital, 171 76 Stockholm, Sweden
    Dev Med Child Neurol 47:312-20. 2005
    ..After this transition, direction-specific postural activity was correlated with spontaneous motor behaviour. This was true, in particular, for dorsal postural activity. The clinical relevance of these findings is discussed...
  75. ncbi request reprint Postural adjustments in preterm infants at 4 and 6 months post-term during voluntary reaching in supine position
    Bjorg Fallang
    Oslo University College, Health Sciences, Physiotherapy Programme, Pilestredet 52, 0167 Oslo, Norway
    Pediatr Res 54:826-33. 2003
    ..We concluded that "still" postural behavior is an adequate postural strategy of preterm infants. But it might be that this postural behavior is an indicator of later dysfunction...
  76. ncbi request reprint Kinematic quality of reaching movements in preterm infants
    Bjørg Fallang
    Oslo University College, Health Sciences, Physiotherapy Programme, Norway
    Pediatr Res 53:836-42. 2003
    ..At the age of 6 mo, the advantage of the low-risk group in reaching behavior had disappeared and a disadvantage in the form of nonoptimal reaching behavior of the high-risk group emerged...
  77. ncbi request reprint Acid-base status at birth, spontaneous motor behaviour at term and 3 months and neurodevelopmental outcome at age 4 years in full-term infants
    Janny Wildschut
    Department of Child Neurology, University Hospital Maastricht, The Netherlands
    Early Hum Dev 81:535-44. 2005
    ....
  78. ncbi request reprint Early development of postural adjustments in standing with and without support
    Asa Hedberg
    Neuropediatric Research Unit Q2 07, Department of Woman and Child Health, Karolinska Institutet, Astrid Lindgrens Children s Hospital, 171 76 Stockholm, Sweden
    Exp Brain Res 178:439-49. 2007
    ....
  79. ncbi request reprint Quality of reaching and postural control in young preterm infants is related to neuromotor outcome at 6 years
    Bjørg Fallang
    Oslo University College, Health Sciences, Physiotherapy Programme, 0130 Oslo, Norway
    Pediatr Res 58:347-53. 2005
    ..This suggests that a relatively immobile postural behavior points to a mild form of brain dysfunction...
  80. pmc Postural dysfunction in children with cerebral palsy: some implications for therapeutic guidance
    Eva Brogren Carlberg
    Department of Woman and Child Health, Neuropediatric Research Unit, Astrid Lindgren Children s Hospital, Stockholm, Sweden
    Neural Plast 12:221-8; discussion 263-72. 2005
    ..The challenge facing us now is to provide evidence about the efficacy of specific treatment approaches facilitating that children reach an optimal level of functioning in daily life...
  81. ncbi request reprint Predicting additional care in young children with neurodevelopmental disability: a systematic literature review
    Anke Meester-Delver
    Department of Rehabilitation, Academic Medical Centre, Amsterdam, The Netherlands
    Dev Med Child Neurol 48:143-50. 2006
    ..However, comprehensive instruments providing such information are currently lacking and, thus, need to be developed...
  82. ncbi request reprint Fetal onset of general movements
    Annemarie B Lüchinger
    Department of Obstetrics and Gynaecology, VU University Medical Centre, 1007 MB, Amsterdam, The Netherlands
    Pediatr Res 63:191-5. 2008
    ..006). The data suggest that initial simple fetal motility is generated by spinal and brainstem circuitries, and the emergence of complex and variable GMs denotes the onset of supraspinal modulation of this spinal and brainstem activity...
  83. pmc Associations of maternal fish intake during pregnancy and breastfeeding duration with attainment of developmental milestones in early childhood: a study from the Danish National Birth Cohort
    Emily Oken
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Clin Nutr 88:789-96. 2008
    ..Few studies have examined the overall effect of maternal fish intake during pregnancy on child development or examined whether the developmental benefits of maternal fish intake are greater in infants breastfed for a shorter duration...
  84. ncbi request reprint Trans isomeric octadecenoic acids are related inversely to arachidonic acid and DHA and positively related to mead acid in umbilical vessel wall lipids
    Tamas Decsi
    Department of Paediatrics, University of Pecs, H 7623 Pecs, Hungary
    Lipids 37:959-65. 2002
    ..01) and vein (r = +0.31, P< 0.01) wall lipids. The present results obtained in a large group of full-term infants suggest that maternal trans FA intake is inversely associated with long-chain PUFA status of the infant at birth...
  85. ncbi request reprint How much loss to follow-up is acceptable in long-term randomised trials and prospective studies?
    Mary S Fewtrell
    Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK
    Arch Dis Child 93:458-61. 2008
  86. doi request reprint How well do care providers know the children with developmental disabilities they care for?
    Anke Meester-Delver
    Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands
    Acta Paediatr 97:608-12. 2008
    ..To assess the knowledge from memory of caregivers about the most significant impairments contributing to additional care needs in children with developmental disabilities in therapeutic toddler groups...
  87. ncbi request reprint The Capacity Profile: a method to classify additional care needs in children with neurodevelopmental disabilities
    Anke Meester-Delver
    Department of Rehabilitation, Academic Medical Center, Amsterdam, The Netherlands
    Dev Med Child Neurol 49:355-60. 2007
    ..The preliminary evidence for the stability over time of such needs according to the CAP should be validated in a prospective study...
  88. ncbi request reprint Test-retest and inter- and intrareliability of the quality of the upper-extremity skills test in preschool-age children with cerebral palsy
    Nienke Haga
    Revalidatie Friesland, Beetsterzwaag, The Netherlands
    Arch Phys Med Rehabil 88:1686-9. 2007
    ..To investigate the test-retest, inter-, and intraobserver reliability of the Quality of Upper Extremity Skills Test (QUEST) in young children with cerebral palsy (CP)...
  89. ncbi request reprint Postural adjustments due to external perturbations during sitting in 1-month-old infants: evidence for the innate origin of direction specificity
    Asa Hedberg
    Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Exp Brain Res 157:10-7. 2004
    ..The finding of a variable repertoire of muscle response patterns, including the 'complete' pattern, refutes the idea that the development of postural adjustments results from gradual addition of appropriate muscles to the synergies...
  90. ncbi request reprint The Kozijavkin method: giving parents false hope?
    Mijna Hadders-Algra
    Lancet 365:842. 2005
  91. ncbi request reprint Atypical performance: how do we deal with that?
    Mijna Hadders-Algra
    Dev Med Child Neurol 49:403. 2007
  92. pmc Postural behavior in children born preterm
    Bjørg Fallang
    Oslo University College, Health Sciences, Physiotherapy Programme, 0130 Oslo, Norway
    Neural Plast 12:175-82; discussion 263-72. 2005
    ....
  93. ncbi request reprint Deficient coordination of associated postural adjustments during a lifting task in children with neurodevelopmental disorders
    Aurelija Jucaite
    Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden
    Dev Med Child Neurol 45:731-42. 2003
    ..Results indicate that children with ADHD and DCD show a spectrum of neural dysfunctions underlying poor motor coordination, which are not specific to the clinical disorder...