R H H Groenwold

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi [Case-control study: the importance of selecting the right controls]
    Rolf H H Groenwold
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Gezondheidszorg, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A5697. 2013
  2. ncbi Progestogens to prevent preterm birth in twin pregnancies: an individual participant data meta-analysis of randomized trials
    Ewoud Schuit
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    BMC Pregnancy Childbirth 12:13. 2012
  3. ncbi [Bias in observational research: 'confounding']
    Rolf H H Groenwold
    Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Gezondheidszorg, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 156:A4221. 2012
  4. ncbi Dealing with missing outcome data in randomized trials and observational studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 175:210-7. 2012
  5. ncbi Balance measures for propensity score methods: a clinical example on beta-agonist use and the risk of myocardial infarction
    Rolf H H Groenwold
    Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 20:1130-7. 2011
  6. ncbi Selection of confounding variables should not be based on observed associations with exposure
    Rolf H H Groenwold
    Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands
    Eur J Epidemiol 26:589-93. 2011
  7. ncbi Reporting of treatment effects from randomized trials: a plea for multivariable risk ratios
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Contemp Clin Trials 32:399-402. 2011
  8. ncbi Confounding in publications of observational intervention studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center, Universiteitsweg 100, STR 6 118, 3584 GC, Utrecht, The Netherlands
    Eur J Epidemiol 22:413-5. 2007
  9. ncbi Subgroup effects despite homogeneous heterogeneity test results
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Med Res Methodol 10:43. 2010
  10. ncbi Sensitivity analyses to estimate the potential impact of unmeasured confounding in causal research
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Epidemiol 39:107-17. 2010

Collaborators

Detail Information

Publications19

  1. ncbi [Case-control study: the importance of selecting the right controls]
    Rolf H H Groenwold
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Gezondheidszorg, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A5697. 2013
    ..We illustrate the case-control study design by an example study into the relation between mobile phone use and the risk of traffic accidents, with a focus on the selection of controls...
  2. ncbi Progestogens to prevent preterm birth in twin pregnancies: an individual participant data meta-analysis of randomized trials
    Ewoud Schuit
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    BMC Pregnancy Childbirth 12:13. 2012
    ....
  3. ncbi [Bias in observational research: 'confounding']
    Rolf H H Groenwold
    Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Gezondheidszorg, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 156:A4221. 2012
    ..Research in the area of confounding is currently directed at the incorporation of external knowledge on unmeasured confounders, the evaluation of instrumental variables, and the impact of time-dependent confounding...
  4. ncbi Dealing with missing outcome data in randomized trials and observational studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 175:210-7. 2012
    ..Multiple imputation, in addition, can accommodate the missing-not-at-random scenario more flexibly, making it especially suited for sensitivity analyses...
  5. ncbi Balance measures for propensity score methods: a clinical example on beta-agonist use and the risk of myocardial infarction
    Rolf H H Groenwold
    Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 20:1130-7. 2011
    ..Our objective was to compare balance measures in clinical data and assessed the association between long-acting inhalation beta-agonist (LABA) use and myocardial infarction...
  6. ncbi Selection of confounding variables should not be based on observed associations with exposure
    Rolf H H Groenwold
    Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands
    Eur J Epidemiol 26:589-93. 2011
    ..80-1.26). Confounding variables should not be discarded based on balanced distributions among exposure groups, because residual confounding due to the omission of confounding variables from the adjustment model can be relevant...
  7. ncbi Reporting of treatment effects from randomized trials: a plea for multivariable risk ratios
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Contemp Clin Trials 32:399-402. 2011
    ..When odds ratios are used, adjustment for baseline covariates should be considered, also when these are well-balanced between the treatment groups...
  8. ncbi Confounding in publications of observational intervention studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center, Universiteitsweg 100, STR 6 118, 3584 GC, Utrecht, The Netherlands
    Eur J Epidemiol 22:413-5. 2007
    ..This study shows only 9% of all papers on observational intervention studies published in peer-reviewed medical journals mention any of the terms (confounding, adjustment, or bias) indicating appreciation of confounding...
  9. ncbi Subgroup effects despite homogeneous heterogeneity test results
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Med Res Methodol 10:43. 2010
    ..Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects...
  10. ncbi Sensitivity analyses to estimate the potential impact of unmeasured confounding in causal research
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Epidemiol 39:107-17. 2010
    ..Although several sensitivity analyses are available, these are used infrequently. This article is intended as a tutorial on sensitivity analyses, in which we discuss three methods to conduct sensitivity analysis...
  11. ncbi Instrumental variables in influenza vaccination studies: mission impossible?!
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, Department of Epidemiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Value Health 13:132-7. 2010
    ..Theoretically, analyses using IVs to control for both observed and unobserved confounding may provide unbiased estimates of influenza vaccine effects. We assessed the usefulness of IV analysis in influenza vaccination studies...
  12. ncbi Quantitative assessment of unobserved confounding is mandatory in nonrandomized intervention studies
    R H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    J Clin Epidemiol 62:22-8. 2009
    ..Our objective was to review methods to control for observed confounding, as well as unobserved confounding..
  13. ncbi Pooling of confounders did not induce residual confounding in influenza vaccination studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Ann Epidemiol 19:432-6. 2009
    ..It has been suggested, however, that the pooling of confounders induces residual confounding, although empirical evidence is scarce. We set out to study the effects of combining several confounders into classes of co-morbidity...
  14. ncbi Impact of influenza vaccination on mortality risk among the elderly
    R H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    Eur Respir J 34:56-62. 2009
    ..After taking unmeasured confounding into account, influenza vaccination is still associated with substantial reduction in mortality risk...
  15. ncbi Poor quality of reporting confounding bias in observational intervention studies: a systematic review
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Ann Epidemiol 18:746-51. 2008
    ..To systematically review observational studies on medical interventions to determine the quality of reporting of confounding...
  16. ncbi Quantifying the potential role of unmeasured confounders: the example of influenza vaccination
    R H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Int J Epidemiol 37:1422-9. 2008
    ....
  17. ncbi How to deal with measures of association: a short guide for the clinician
    M J Knol
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Cerebrovasc Dis 33:98-103. 2012
    ..By means of examples, we will discuss the different measures of association for the three main study designs used in clinical research: randomized controlled trial, observational cohort study and case-control study...
  18. ncbi Cause-specific long-term mortality rates in patients recovered from community-acquired pneumonia as compared with the general Dutch population
    A H W Bruns
    Department of Internal Medicine and Infectious Diseases, Division of Medicine, University Medical Centre, Utrecht, The Netherlands
    Clin Microbiol Infect 17:763-8. 2011
    ..After an episode of CAP, optimization of treatment of comorbidities, such as treatment for COPD, might improve long-term survival rates...
  19. ncbi Association between cannabis and psychiatric hospitalization
    C D Schubart
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
    Acta Psychiatr Scand 123:368-75. 2011
    ..To investigate the relationship between cannabis use and mental health...