Genomes and Genes


Albert K Groen


Affiliation: University Medical Center Groningen
Country: The Netherlands


  1. van der Geest R, Ouweneel A, van der Sluis R, Groen A, Van Eck M, Hoekstra M. Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice. Toxicol Appl Pharmacol. 2016;306:1-7 pubmed publisher
    ..In conclusion, we have shown that endogenous glucocorticoids exacerbate the liver injury and hypercholesterolemia associated with acute cholestasis in mice. ..
  2. Groen A, Kuipers F. Bile acid look-alike controls life span in C. elegans. Cell Metab. 2013;18:151-2 pubmed publisher
    ..Magner et al. (2013) now show that, in C. elegans, the nuclear receptor NHR-8 is key in regulation of cholesterol balance and production of dafachronic acid, a bile acid-like steroid that controls longevity. ..
  3. Out C, Patankar J, Doktorova M, Boesjes M, Bos T, de Boer S, et al. Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4. J Hepatol. 2015;63:697-704 pubmed publisher
    ..Our studies expand current knowledge on the bacterial control of bile acid homeostasis. ..