W M Gommans

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. ncbi Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill
    W M Gommans
    Department of Therapeutic Gene Modulation, University of Groningen A. Deusinglaan 1, Groningen, The Netherlands
    J Control Release 116:e64-6. 2006
  2. ncbi An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents
    M G Rots
    Department of Therapeutic Gene Modulation, Groningen University Institute for Drug Exploration, 9713 AV Groningen, The Netherlands
    J Gene Med 8:35-41. 2006
  3. ncbi The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context
    W M Gommans
    Department of Therapeutic Gene Modulation, University Center for Pharmacy, University Groningen, Groningen, The Netherlands
    Cancer Gene Ther 13:150-8. 2006
  4. ncbi Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter
    W M Gommans
    Department of Therapeutic Gene Modulation, Groningen University Institute for Drug Exploration, The Netherlands
    J Control Release 117:1-10. 2007

Detail Information

Publications4

  1. ncbi Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill
    W M Gommans
    Department of Therapeutic Gene Modulation, University of Groningen A. Deusinglaan 1, Groningen, The Netherlands
    J Control Release 116:e64-6. 2006
  2. ncbi An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents
    M G Rots
    Department of Therapeutic Gene Modulation, Groningen University Institute for Drug Exploration, 9713 AV Groningen, The Netherlands
    J Gene Med 8:35-41. 2006
    ..We present a clinically relevant tissue slice technology to preclinically test improved vector characteristics...
  3. ncbi The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context
    W M Gommans
    Department of Therapeutic Gene Modulation, University Center for Pharmacy, University Groningen, Groningen, The Netherlands
    Cancer Gene Ther 13:150-8. 2006
    ..This study demonstrates the value of the EGP-2 promoter to restrict transgene expression to a broad range of tumor types, thereby preventing liver toxicity...
  4. ncbi Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter
    W M Gommans
    Department of Therapeutic Gene Modulation, Groningen University Institute for Drug Exploration, The Netherlands
    J Control Release 117:1-10. 2007
    ..This report clearly shows the potency of the EGP-2 promoter to mediate highly efficient and specific adenoviral replication for carcinoma gene therapy...