Elbert Geuze

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi request reprint Neural correlates of associative learning and memory in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, PO Box 90 000, 3509AA Utrecht, The Netherlands
    J Psychiatr Res 42:659-69. 2008
  2. ncbi request reprint Precuneal activity during encoding in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Ministry of Defense, Utrecht, The Netherlands
    Prog Brain Res 167:293-7. 2008
  3. ncbi request reprint Thinner prefrontal cortex in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre, Military Mental Healthcare, Ministry of Defence, Utrecht, The Netherlands
    Neuroimage 41:675-81. 2008
  4. doi request reprint Glucocorticoid receptor number predicts increase in amygdala activity after severe stress
    Elbert Geuze
    Research Centre, Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1837-44. 2012
  5. doi request reprint Neuropsychological performance is related to current social and occupational functioning in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Depress Anxiety 26:7-15. 2009
  6. ncbi request reprint Altered pain processing in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Arch Gen Psychiatry 64:76-85. 2007
  7. ncbi request reprint Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder
    E Geuze
    Research Centre Military Mental Healthcare, Ministry of Defense, Utrecht, The Netherlands
    Mol Psychiatry 13:74-83, 3. 2008
  8. ncbi request reprint Neuroimaging of pain perception in Dutch veterans with and without posttraumatic stress disorder: preliminary results
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan, 100 3584, CX, Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:401-4. 2006
  9. doi request reprint Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1822-36. 2012
  10. doi request reprint A prospective study on personality and the cortisol awakening response to predict posttraumatic stress symptoms in response to military deployment
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    J Psychiatr Res 45:713-9. 2011

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Neural correlates of associative learning and memory in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, PO Box 90 000, 3509AA Utrecht, The Netherlands
    J Psychiatr Res 42:659-69. 2008
    ..Deficits in memory performance in PTSD appear to be related to altered activity in fronto-temporal areas during both the encoding and retrieval phase of memory processing...
  2. ncbi request reprint Precuneal activity during encoding in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Ministry of Defense, Utrecht, The Netherlands
    Prog Brain Res 167:293-7. 2008
    ..The precuneus was less activated in veterans with PTSD, which correlated significantly with the severity of PTSD. Like fronto-temporal regions the precuneus is differentially activated during memory formation in veterans with PTSD...
  3. ncbi request reprint Thinner prefrontal cortex in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre, Military Mental Healthcare, Ministry of Defence, Utrecht, The Netherlands
    Neuroimage 41:675-81. 2008
    ..Cortical thickness correlated with memory measures in the veterans without PTSD, but not in the veterans with PTSD. Cortical thinning in these regions may thus correspond to functional abnormalities observed in patients with PTSD...
  4. doi request reprint Glucocorticoid receptor number predicts increase in amygdala activity after severe stress
    Elbert Geuze
    Research Centre, Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1837-44. 2012
    ..However, to the best of our knowledge, no previous study has investigated GR number in PBMCs and amygdala function in humans...
  5. doi request reprint Neuropsychological performance is related to current social and occupational functioning in veterans with posttraumatic stress disorder
    Elbert Geuze
    Research Centre Military Mental Health, Ministry of Defense, Utrecht, The Netherlands
    Depress Anxiety 26:7-15. 2009
    ..However, most of these studies had several methodological disadvantages. None of these studies assessed parameters related to social or occupational functioning...
  6. ncbi request reprint Altered pain processing in veterans with posttraumatic stress disorder
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Arch Gen Psychiatry 64:76-85. 2007
    ..Several brain areas related to pain processing are implicated in PTSD. To our knowledge, no functional imaging study has discussed whether patients with PTSD experience and process pain in a different way than control subjects...
  7. ncbi request reprint Reduced GABAA benzodiazepine receptor binding in veterans with post-traumatic stress disorder
    E Geuze
    Research Centre Military Mental Healthcare, Ministry of Defense, Utrecht, The Netherlands
    Mol Psychiatry 13:74-83, 3. 2008
    ....
  8. ncbi request reprint Neuroimaging of pain perception in Dutch veterans with and without posttraumatic stress disorder: preliminary results
    Elbert Geuze
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan, 100 3584, CX, Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:401-4. 2006
    ..Fixed affects analysis demonstrated that stimuli subjectively perceived as more painful resulted in increased activation of the caudal ACC, whereas less painful stimuli resulted in increased activation of the rostral ACC in both groups...
  9. doi request reprint Glucocorticoid sensitivity of leukocytes predicts PTSD, depressive and fatigue symptoms after military deployment: A prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychoneuroendocrinology 37:1822-36. 2012
    ..e. dexamethasone: DEX) assessed before military deployment predicts high levels of PTSD, depressive, and/or fatigue symptoms 6 months after return from deployment...
  10. doi request reprint A prospective study on personality and the cortisol awakening response to predict posttraumatic stress symptoms in response to military deployment
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center Utrecht, Utrecht, The Netherlands
    J Psychiatr Res 45:713-9. 2011
    ..However, the number of previous deployments was not related to development of PTSD symptoms. The total model explained 24% of variance in PTSD symptoms after military deployment...
  11. pmc IL-1β reactivity and the development of severe fatigue after military deployment: a longitudinal study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands
    J Neuroinflammation 9:205. 2012
    ..Based on this concept, we assessed the reactivity of peripheral blood cells to IL-1β in vitro as a novel approach to investigate whether severe fatigue is associated with increased pro-inflammatory signaling...
  12. pmc Cytokine production by leukocytes of military personnel with depressive symptoms after deployment to a combat-zone: a prospective, longitudinal study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease NIDOD, University Medical Center, Utrecht, Utrecht, The Netherlands
    PLoS ONE 6:e29142. 2011
    ..In addition, deployment to a combat-zone affects the capacity of T-cells and monocytes to produce cytokines and chemokines until at least 6 months after return...
  13. ncbi request reprint Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study
    Mirjam van Zuiden
    Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 71:309-16. 2012
    ..We investigated whether glucocorticoid receptor (GR) pathway components assessed in leukocytes before military deployment represent preexisting vulnerability factors for development of PTSD symptoms...
  14. ncbi request reprint Pharmacotherapeutic treatment of nightmares and insomnia in posttraumatic stress disorder: an overview of the literature
    Saskia van Liempt
    Rudolf Magnus Institute of Neurosciences and Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Ann N Y Acad Sci 1071:502-7. 2006
    ..Objective parameters for insomnia and nightmares need to be identified for understanding underlying mechanisms of disturbed sleep in PTSD, and for evaluating therapy...
  15. ncbi request reprint Deployment-related severe fatigue with depressive symptoms is associated with increased glucocorticoid binding to peripheral blood mononuclear cells
    Mirjam van Zuiden
    Laboratory of Psychoneuroimmunology, University Medical Center Utrecht, Utrecht, The Netherlands
    Brain Behav Immun 23:1132-9. 2009
    ..These results indicate that high glucocorticoid binding to PBMCs might represent a vulnerability factor for the development of severe fatigue with depressive symptoms after a sustained period of stress, such as deployment...
  16. ncbi request reprint Differences in the response to the combined DEX-CRH test between PTSD patients with and without co-morbid depressive disorder
    Carien DE Kloet
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Psychoneuroendocrinology 33:313-20. 2008
    ....
  17. ncbi request reprint Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review
    C S de Kloet
    Department of Military Psychiatry, Central Military Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Psychiatr Res 40:550-67. 2006
    ....
  18. doi request reprint Neural correlates of personality: an integrative review
    Mitzy Kennis
    Research Centre Military Mental Healthcare, Lundlaan 1, 3584 EZ Utrecht, The Netherlands
    Neurosci Biobehav Rev 37:73-95. 2013
    ..Further research is proposed to potentially reveal new insight in the neural subsystems governing basic human behavior...
  19. ncbi request reprint Self-reported early trauma as a predictor of adult personality: a study in a military sample
    Arthur R Rademaker
    Utrecht University, and Research Institute for Psychology and Health and Research Centre Military Mental Healthcare, Utrecht, The Netherlands
    J Clin Psychol 64:863-75. 2008
    ..They show that early trauma may become ingrained in personality and hamper the potential to effectively engage in social interactions, increasing the risk of emotional and cognitive problems...
  20. ncbi request reprint Enhanced cortisol suppression in response to dexamethasone administration in traumatized veterans with and without posttraumatic stress disorder
    C S de Kloet
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Psychoneuroendocrinology 32:215-26. 2007
    ..While enhanced cortisol suppression in response to dexamethasone is one of the most consistent biological findings in posttraumatic stress disorder (PTSD), the relative contribution of trauma exposure to this finding remains unclear...
  21. ncbi request reprint Leukocyte glucocorticoid receptor expression and immunoregulation in veterans with and without post-traumatic stress disorder
    C S de Kloet
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Mol Psychiatry 12:443-53. 2007
    ..DEX resistance of in vitro immune activity was not a general phenomenon, but was restricted to specific immune functions...
  22. ncbi request reprint Elevated plasma arginine vasopressin levels in veterans with posttraumatic stress disorder
    C S de Kloet
    Department of Military Psychiatry, Central Military Hospital, Magnus Institute of Neuroscience, Utrecht, The Netherlands
    J Psychiatr Res 42:192-8. 2008
    ..In order to evaluate the effect of trauma and PTSD on central AVP secretion we assessed plasma AVP levels in equally trauma exposed veterans with and without PTSD and a non-traumatized healthy control group...
  23. ncbi request reprint Pharmacotherapy for disordered sleep in post-traumatic stress disorder: a systematic review
    Saskia van Liempt
    Department of Military Psychiatry, Central Military Hospital, Utrecht, The Netherlands
    Int Clin Psychopharmacol 21:193-202. 2006
    ..Some recent studies show promising results, especially for alpha1-adrenoceptor and 5-HT2 receptor antagonists. However, randomized controlled trials with larger populations need to be conducted...
  24. doi request reprint Attachment representations in Dutch veterans with and without deployment-related PTSD
    D Harari
    Psychotrauma Diagnostic Centre, Utrecht, The Netherlands
    Attach Hum Dev 11:515-36. 2009
    ..AAI unresolved state of mind with respect to deployment related trauma and PTSD correlate strongly, due to the common core phenomenon of lack of integration...
  25. ncbi request reprint MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders
    E Geuze
    Department of Military Psychiatry, Central Military Hospital, Utrecht, Rudolf Magnus Institute of Neuroscience, Mailbox B 01 2 06, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Mol Psychiatry 10:160-84. 2005
    ..Possible mechanisms of hippocampal volume loss in neuropsychiatric disorders are discussed...
  26. ncbi request reprint MR-based in vivo hippocampal volumetrics: 1. Review of methodologies currently employed
    E Geuze
    Department of Military Psychiatry, Central Military Hospital, Utrecht, Rudolf Magnus Institute of Neuroscience, Mailbox B 01 2 06, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Mol Psychiatry 10:147-59. 2005
    ..The findings are discussed in relation to optimizing determination of hippocampal volume...