M M Faas

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi request reprint Species differences in the effect of pregnancy on lymphocyte cytokine production between human and rat
    Marijke M Faas
    Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Leukoc Biol 78:946-53. 2005
  2. ncbi request reprint Monocyte activation, but not granulocyte activation, is inhibited in the presence of developing ovarian follicles
    M M Faas
    Transplantation Biology and Immunoendocrinology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Reprod Immunol 70:21-32. 2006
  3. doi request reprint Plasma from preeclamptic women activates endothelial cells via monocyte activation in vitro
    Marijke M Faas
    Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Reprod Immunol 87:28-38. 2010
  4. doi request reprint Extracellular ATP induces albuminuria in pregnant rats
    Marijke M Faas
    Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    Nephrol Dial Transplant 25:2468-78. 2010
  5. doi request reprint Plasma of pregnant and preeclamptic women activates monocytes in vitro
    M M Faas
    Department of Pathology and Laboratory Medicine, Transplantation Biology and Immunoendocrinology, Division of Medical Biology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Am J Obstet Gynecol 199:84.e1-8. 2008
  6. ncbi request reprint Cytokine production of in vitro stimulated peripheral lymphocytes during the course of pregnancy and pseudopregnancy in the rat
    M M Faas
    Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    Am J Reprod Immunol 55:282-90. 2006
  7. ncbi request reprint Total white blood cell counts and LPS-induced TNF alpha production by monocytes of pregnant, pseudopregnant and cyclic rats
    M M Faas
    Reproductive Immunology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    J Reprod Immunol 59:39-52. 2003
  8. ncbi request reprint The immune response during the luteal phase of the ovarian cycle: increasing sensitivity of human monocytes to endotoxin
    A Bouman
    Department of Obstetrics and Gynaecology, University and University Hospital Groningen, Groningen, The Netherlands
    Fertil Steril 76:555-9. 2001
  9. ncbi request reprint Superoxide-mediated glomerulopathy in the endotoxin-treated pregnant rat
    M M Faas
    Division of Reproductive Biology, Department of Obstetrics and Gynaecology, University of Groningen, The Netherlands
    Kidney Blood Press Res 21:432-7. 1998
  10. doi request reprint Effects of acute cytomegalovirus infection on rat islet allograft survival
    M J Smelt
    Department of Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cell Transplant 20:1271-83. 2011

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Species differences in the effect of pregnancy on lymphocyte cytokine production between human and rat
    Marijke M Faas
    Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Leukoc Biol 78:946-53. 2005
    ..In conclusion, although the data from humans concur with the Th1/Th2 paradigm, the data from rats do not concur with this paradigm. The present studies therefore challenge the classical Th1/Th2 paradigm during pregnancy...
  2. ncbi request reprint Monocyte activation, but not granulocyte activation, is inhibited in the presence of developing ovarian follicles
    M M Faas
    Transplantation Biology and Immunoendocrinology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Reprod Immunol 70:21-32. 2006
    ....
  3. doi request reprint Plasma from preeclamptic women activates endothelial cells via monocyte activation in vitro
    Marijke M Faas
    Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Reprod Immunol 87:28-38. 2010
    ..Our data suggest that plasma of preeclamptic women activates monocytes, and that these monocytes subsequently activate endothelial cells...
  4. doi request reprint Extracellular ATP induces albuminuria in pregnant rats
    Marijke M Faas
    Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    Nephrol Dial Transplant 25:2468-78. 2010
    ..As circulating plasma ATP concentrations are increased in pre-eclampsia, we tested whether increased plasma ATP is able to induce albuminuria during pregnancy...
  5. doi request reprint Plasma of pregnant and preeclamptic women activates monocytes in vitro
    M M Faas
    Department of Pathology and Laboratory Medicine, Transplantation Biology and Immunoendocrinology, Division of Medical Biology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Am J Obstet Gynecol 199:84.e1-8. 2008
    ..The objective of the study was to test the hypothesis that factors circulating in the plasma of pregnant women and women with preeclampsia activate monocytes...
  6. ncbi request reprint Cytokine production of in vitro stimulated peripheral lymphocytes during the course of pregnancy and pseudopregnancy in the rat
    M M Faas
    Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
    Am J Reprod Immunol 55:282-90. 2006
    ..Does maternal lymphocyte cytokine production after in vitro stimulation vary with the stage of pregnancy in the rat?..
  7. ncbi request reprint Total white blood cell counts and LPS-induced TNF alpha production by monocytes of pregnant, pseudopregnant and cyclic rats
    M M Faas
    Reproductive Immunology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    J Reprod Immunol 59:39-52. 2003
    ..For the post-implantation phase of pregnancy, this is once more stressed by the increased numbers of WBC and PMN...
  8. ncbi request reprint The immune response during the luteal phase of the ovarian cycle: increasing sensitivity of human monocytes to endotoxin
    A Bouman
    Department of Obstetrics and Gynaecology, University and University Hospital Groningen, Groningen, The Netherlands
    Fertil Steril 76:555-9. 2001
    ..To test the hypothesis that during the luteal phase of the human ovarian cycle, as compared with the follicular phase, the percentage of cytokines producing peripheral monocytes after in vitro stimulation with endotoxin is increased...
  9. ncbi request reprint Superoxide-mediated glomerulopathy in the endotoxin-treated pregnant rat
    M M Faas
    Division of Reproductive Biology, Department of Obstetrics and Gynaecology, University of Groningen, The Netherlands
    Kidney Blood Press Res 21:432-7. 1998
    ....
  10. doi request reprint Effects of acute cytomegalovirus infection on rat islet allograft survival
    M J Smelt
    Department of Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cell Transplant 20:1271-83. 2011
    ..Also, our data demonstrate that new approaches for preventing virus-induced islet allograft failure may be required...
  11. ncbi request reprint Glomerular immunoglobulin deposits induce glomerular inflammation in pregnant but not in non-pregnant rats
    M M Faas
    Reproductive Immunology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, Groningen, The Netherlands
    Am J Reprod Immunol 49:57-63. 2003
    ..Does an inflammatory stimulus evoke a more intense inflammatory response in pregnant rats as compared with non-pregnant rats?..
  12. doi request reprint Hydrogen sulfide producing enzymes in pregnancy and preeclampsia
    K M Holwerda
    Department of Pathology and Medical Biology, Division of Pathology, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9713 GZ Groningen, The Netherlands
    Placenta 33:518-21. 2012
    ..002) in early-onset preeclampsia, while CSE mRNA is unchanged. Thus, down regulation of CBS during early-onset preeclampsia may result in less H(2)S-production and may aid in the anti-angiogenic state...
  13. doi request reprint LPS promotes pre-osteoclast activity by up-regulating CXCR4 via TLR-4
    Q Xing
    Department of Orthodontics, University Medical Centre Groningen, University of Groningen, Hanzeplein 1 triade 24, 9700 RB Groningen, The Netherlands
    J Dent Res 90:157-62. 2011
    ..In conclusion, the present study demonstrated, for the first time, that the up-regulated expression of CXCR4 in pre-osteoclasts by LPS stimulation is involved in LPS-induced bone resorption...
  14. ncbi request reprint Corticosterone treatment of pregnant low dose endotoxin-treated rats: inhibition of the inflammatory response
    M M Faas
    Department of Obstetrics and Gynecology, University of Groningen, The Netherlands
    Am J Reprod Immunol 44:178-83. 2000
    ..Can the endotoxin-induced inflammatory response, underlying experimental pre-eclampsia, in pregnant rats be inhibited by corticosterone?..
  15. pmc Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism
    M J Smelt
    Transplantation Biology and Immunoendocrinology, Section of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, 9700 RB Groningen, The Netherlands
    Exp Diabetes Res 2008:165360. 2008
    ..This method is also a fast and reliable method to measure beta cell functional viability. A conceivable application is assessing beta cell viability before transplantation...
  16. doi request reprint Altered expression of immune-associated genes in first-trimester human decidua of pregnancies later complicated with hypertension or foetal growth restriction
    J R Prins
    Department of Obstetrics and Gynaecology, University Medical Center Groningen, P O Box 30001, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Placenta 33:453-5. 2012
    ..Lower Gata3 (Th2) mRNA expression was found in deciduas of pregnancies with later foetal growth restriction. Our results suggest that adverse pregnancy outcomes are associated with immunological disturbances in first-trimester deciduas...
  17. pmc Monocyte intracellular cytokine production during human endotoxaemia with or without a second in vitro LPS challenge: effect of RWJ-67657, a p38 MAP-kinase inhibitor, on LPS-hyporesponsiveness
    M M Faas
    Reproductive Immunology, Medical Biology Branch, Department of Pathology, University of Groningen, The Netherlands
    Clin Exp Immunol 127:337-43. 2002
    ..Whether this result can be extended to the clinical situation remains to be elucidated. Patients with sepsis or an otherwise high risk for multi-organ failure are potential study groups...
  18. ncbi request reprint The immunology of successful pregnancy
    A L Veenstra van Nieuwenhoven
    Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands
    Hum Reprod Update 9:347-57. 2003
    ..Yet, the question of why the semi-allogeneic fetus is not rejected by the mother remains unresolved. The present review provides an update of current knowledge on the subject of the so-called 'immunological paradox of pregnancy'...
  19. ncbi request reprint Developing ovarian follicles inhibit the endotoxin-induced glomerular inflammatory reaction in pseudopregnant rats
    Marijke M Faas
    Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, The Netherlands
    Am J Reprod Immunol 51:385-9. 2004
    ..We tested the hypothesis that developing ovarian follicles produce factors inhibiting the endotoxin induced inflammatory response...
  20. ncbi request reprint Plasma hemopexin activity in pregnancy and preeclampsia
    Winston W Bakker
    Departments of Pathology and Laboratory Medicine, University Medical Center of Groningen and University of Groningen Groningen The Netherlands
    Hypertens Pregnancy 26:227-39. 2007
    ..Plasma hemopexin activity, associated with increased vascular permeability, was evaluated in healthy pregnant and non-pregnant women and in pre-eclamptic women...
  21. ncbi request reprint The incidence of pregnancy-induced hypertension and smoking: an alternative explanation?
    Winston W Bakker
    Am J Obstet Gynecol 197:556; author reply 556-7. 2007
  22. doi request reprint Cytokine production by monocytes, NK cells, and lymphocytes is different in preeclamptic patients as compared with normal pregnant women
    Angelique L Veenstra van Nieuwenhoven
    Department of Obstetrics and Gynecology, University Medical Centre Groningen, Groningen, The Netherlands
    Hypertens Pregnancy 27:207-24. 2008
    ..To measure cytokine production in ex vivo stimulated leukocyte populations of women with normal pregnancy and those with preeclampsia...
  23. ncbi request reprint Towards stem-cell therapy in the endocrine pancreas
    Shanti T Gangaram-Panday
    Transplantation Biology and Immunoendocrinology, Section of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Groningen, The Netherlands
    Trends Mol Med 13:164-73. 2007
    ....
  24. ncbi request reprint Absence of in vivo generalized pro-inflammatory endothelial activation in severe, early-onset preeclampsia
    Rogier B Donker
    Department of Obstetrics and Gynecology, Groningen University Institute for Drug Exploration, University Medical Center Groningen, Groningen, The Netherlands
    J Soc Gynecol Investig 12:518-28. 2005
    ..Therefore, this study aimed to investigate the presence of generalized proinflammatory endothelial activation in severe, early-onset preeclampsia in vivo...
  25. ncbi request reprint Alginate-based microcapsules for immunoisolation of pancreatic islets
    Paul De Vos
    Department of Pathology and Laboratory Medicine, Division of Medical Biology, University Hospital of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Biomaterials 27:5603-17. 2006
    ..New approaches in which newly discovered inflammatory responses are silenced bring the technology of transplantation of immunoisolated cells close to clinical application...
  26. ncbi request reprint Factors influencing insulin secretion from encapsulated islets
    Bart J de Haan
    Immunoendocrinology, Department of Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Cell Transplant 12:617-25. 2003
    ..We conclude that capsules containing small islets (90-120 microm) and a membrane with a lower permeability than routinely applied is preferred in order to obtain a graft with adequate glucose-induced insulin responses...
  27. ncbi request reprint The effect of testosterone on cytokine production in the specific and non-specific immune response
    Elske Posma
    Department of Obstetrics and Gynaecology, University Hospital Groningen, Groningen, The Netherlands
    Am J Reprod Immunol 52:237-43. 2004
    ..In the present study, we investigated whether testosterone may explain these differences...
  28. ncbi request reprint Altered monocyte function in experimental preeclampsia in the rat
    Marijke M Faas
    Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, Groningen, The Netherlands
    Am J Obstet Gynecol 191:1192-8. 2004
    ..In the present study, we evaluated functional activity of monocytes in experimental preeclampsia induced by low-dose endotoxin infusion...
  29. ncbi request reprint Factors influencing functional survival of microencapsulated islet grafts
    Paul De Vos
    Transplantation Biology and Immunoendocrinology, Department of Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    Cell Transplant 13:515-24. 2004
    ..Our observations indicate that we should focus on reduction of macrophage activation and on improving the nutrition of encapsulated islets to prevent islet cell death...
  30. ncbi request reprint Gender difference in the non-specific and specific immune response in humans
    Annechien Bouman
    Department of Obstetrics and Gynecology, University Hospital Groningen, Groningen, The Netherlands
    Am J Reprod Immunol 52:19-26. 2004
    ..The purpose of this present ex vivo study is to get insight in the sex differences of the basic non-specific and specific immune response...
  31. ncbi request reprint Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycle
    Angelique L Veenstra van Nieuwenhoven
    Department of Obstetrics and Gynecology, University Hospital, Groningen, The Netherlands
    Fertil Steril 77:1032-7. 2002
    ....
  32. ncbi request reprint Factors influencing isolation of functional pancreatic rat islets
    Bart J de Haan
    Transplantation Biology and Immunoendocrinology, Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Groningen, The Netherlands
    Pancreas 29:e15-22. 2004
    ..Our observations indicate that strain and weight of the rat donor, the source of bovine serum albumin, and the culture conditions of islets are pertinent factors in efficacious isolation of islets...
  33. ncbi request reprint Monocyte cytokine production during pregnancy
    Marijke M Faas
    J Leukoc Biol 75:153-4; author reply 155-6. 2004
  34. ncbi request reprint Endotoxin-induced cytokine production of monocytes of third-trimester pregnant women compared with women in the follicular phase of the menstrual cycle
    Angelique L Veenstra van Nieuwenhoven
    Department of Obstetrics and Gynecology, University Hospital Groningen, The Netherlands
    Am J Obstet Gynecol 188:1073-7. 2003
    ..Little is known about the function of the innate immune response during pregnancy. We therefore investigated monocyte cytokine production, as a measure of monocyte function, in pregnant women compared with nonpregnant women...
  35. ncbi request reprint Chemistry and the biological response against immunoisolating alginate-polycation capsules of different composition
    Sara Ponce
    Faculty of Pharmacy, Laboratory of Pharmacy and Pharmaceutical Technology, University of the Basque Country, Vitoria Gasteiz, Spain
    Biomaterials 27:4831-9. 2006
    ..Our results suggest that PLL is the best option available and that we should avoid using PLO and PDL in its present form since it is our goals to produce capsules that lack overgrowth and do not induce an immunological response as such...
  36. ncbi request reprint Zeta-potentials of alginate-PLL capsules: a predictive measure for biocompatibility?
    Paul De Vos
    Department of Pathology and Laboratory Medicine, Section of Medical Biology, Division of Immunoendocrinology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    J Biomed Mater Res A 80:813-9. 2007
    ..Our results suggest that we should not only consider the capsule properties under physiological circumstances to explain bioincompatibility but also the capsule features during common pathophysiological situations...