Research Topics
| M M FaasSummaryAffiliation: University Medical Center Groningen Country: The Netherlands Publications
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Detail Information
Publications
Species differences in the effect of pregnancy on lymphocyte cytokine production between human and ratMarijke M Faas
Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
J Leukoc Biol 78:946-53. 2005..In conclusion, although the data from humans concur with the Th1/Th2 paradigm, the data from rats do not concur with this paradigm. The present studies therefore challenge the classical Th1/Th2 paradigm during pregnancy...- Monocyte activation, but not granulocyte activation, is inhibited in the presence of developing ovarian folliclesM M Faas
Transplantation Biology and Immunoendocrinology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
J Reprod Immunol 70:21-32. 2006.... 
Plasma from preeclamptic women activates endothelial cells via monocyte activation in vitroMarijke M Faas
Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
J Reprod Immunol 87:28-38. 2010..Our data suggest that plasma of preeclamptic women activates monocytes, and that these monocytes subsequently activate endothelial cells...- Extracellular ATP induces albuminuria in pregnant ratsMarijke M Faas
Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
Nephrol Dial Transplant 25:2468-78. 2010..As circulating plasma ATP concentrations are increased in pre-eclampsia, we tested whether increased plasma ATP is able to induce albuminuria during pregnancy... - Plasma of pregnant and preeclamptic women activates monocytes in vitroM M Faas
Department of Pathology and Laboratory Medicine, Transplantation Biology and Immunoendocrinology, Division of Medical Biology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
Am J Obstet Gynecol 199:84.e1-8. 2008..The objective of the study was to test the hypothesis that factors circulating in the plasma of pregnant women and women with preeclampsia activate monocytes... - Cytokine production of in vitro stimulated peripheral lymphocytes during the course of pregnancy and pseudopregnancy in the ratM M Faas
Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
Am J Reprod Immunol 55:282-90. 2006..Does maternal lymphocyte cytokine production after in vitro stimulation vary with the stage of pregnancy in the rat?.. - Total white blood cell counts and LPS-induced TNF alpha production by monocytes of pregnant, pseudopregnant and cyclic ratsM M Faas
Reproductive Immunology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
J Reprod Immunol 59:39-52. 2003..For the post-implantation phase of pregnancy, this is once more stressed by the increased numbers of WBC and PMN... - The immune response during the luteal phase of the ovarian cycle: increasing sensitivity of human monocytes to endotoxinA Bouman
Department of Obstetrics and Gynaecology, University and University Hospital Groningen, Groningen, The Netherlands
Fertil Steril 76:555-9. 2001..To test the hypothesis that during the luteal phase of the human ovarian cycle, as compared with the follicular phase, the percentage of cytokines producing peripheral monocytes after in vitro stimulation with endotoxin is increased... - Superoxide-mediated glomerulopathy in the endotoxin-treated pregnant ratM M Faas
Division of Reproductive Biology, Department of Obstetrics and Gynaecology, University of Groningen, The Netherlands
Kidney Blood Press Res 21:432-7. 1998.... - Effects of acute cytomegalovirus infection on rat islet allograft survivalM J Smelt
Department of Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
Cell Transplant 20:1271-83. 2011..Also, our data demonstrate that new approaches for preventing virus-induced islet allograft failure may be required... - Glomerular immunoglobulin deposits induce glomerular inflammation in pregnant but not in non-pregnant ratsM M Faas
Reproductive Immunology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, Groningen, The Netherlands
Am J Reprod Immunol 49:57-63. 2003..Does an inflammatory stimulus evoke a more intense inflammatory response in pregnant rats as compared with non-pregnant rats?.. - Hydrogen sulfide producing enzymes in pregnancy and preeclampsiaK M Holwerda
Department of Pathology and Medical Biology, Division of Pathology, University Medical Center Groningen, Hanzeplein 1, PO Box 30001, 9713 GZ Groningen, The Netherlands
Placenta 33:518-21. 2012..002) in early-onset preeclampsia, while CSE mRNA is unchanged. Thus, down regulation of CBS during early-onset preeclampsia may result in less H(2)S-production and may aid in the anti-angiogenic state... - LPS promotes pre-osteoclast activity by up-regulating CXCR4 via TLR-4Q Xing
Department of Orthodontics, University Medical Centre Groningen, University of Groningen, Hanzeplein 1 triade 24, 9700 RB Groningen, The Netherlands
J Dent Res 90:157-62. 2011..In conclusion, the present study demonstrated, for the first time, that the up-regulated expression of CXCR4 in pre-osteoclasts by LPS stimulation is involved in LPS-induced bone resorption... - Corticosterone treatment of pregnant low dose endotoxin-treated rats: inhibition of the inflammatory responseM M Faas
Department of Obstetrics and Gynecology, University of Groningen, The Netherlands
Am J Reprod Immunol 44:178-83. 2000..Can the endotoxin-induced inflammatory response, underlying experimental pre-eclampsia, in pregnant rats be inhibited by corticosterone?.. 
Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolismM J Smelt
Transplantation Biology and Immunoendocrinology, Section of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, 9700 RB Groningen, The Netherlands
Exp Diabetes Res 2008:165360. 2008..This method is also a fast and reliable method to measure beta cell functional viability. A conceivable application is assessing beta cell viability before transplantation...- Altered expression of immune-associated genes in first-trimester human decidua of pregnancies later complicated with hypertension or foetal growth restrictionJ R Prins
Department of Obstetrics and Gynaecology, University Medical Center Groningen, P O Box 30001, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Placenta 33:453-5. 2012..Lower Gata3 (Th2) mRNA expression was found in deciduas of pregnancies with later foetal growth restriction. Our results suggest that adverse pregnancy outcomes are associated with immunological disturbances in first-trimester deciduas... - Monocyte intracellular cytokine production during human endotoxaemia with or without a second in vitro LPS challenge: effect of RWJ-67657, a p38 MAP-kinase inhibitor, on LPS-hyporesponsivenessM M Faas
Reproductive Immunology, Medical Biology Branch, Department of Pathology, University of Groningen, The Netherlands
Clin Exp Immunol 127:337-43. 2002..Whether this result can be extended to the clinical situation remains to be elucidated. Patients with sepsis or an otherwise high risk for multi-organ failure are potential study groups... - The immunology of successful pregnancyA L Veenstra van Nieuwenhoven
Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands
Hum Reprod Update 9:347-57. 2003..Yet, the question of why the semi-allogeneic fetus is not rejected by the mother remains unresolved. The present review provides an update of current knowledge on the subject of the so-called 'immunological paradox of pregnancy'... - Developing ovarian follicles inhibit the endotoxin-induced glomerular inflammatory reaction in pseudopregnant ratsMarijke M Faas
Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, The Netherlands
Am J Reprod Immunol 51:385-9. 2004..We tested the hypothesis that developing ovarian follicles produce factors inhibiting the endotoxin induced inflammatory response... - Plasma hemopexin activity in pregnancy and preeclampsiaWinston W Bakker
Departments of Pathology and Laboratory Medicine, University Medical Center of Groningen and University of Groningen Groningen The Netherlands
Hypertens Pregnancy 26:227-39. 2007..Plasma hemopexin activity, associated with increased vascular permeability, was evaluated in healthy pregnant and non-pregnant women and in pre-eclamptic women... - The incidence of pregnancy-induced hypertension and smoking: an alternative explanation?Winston W Bakker
Am J Obstet Gynecol 197:556; author reply 556-7. 2007 - Cytokine production by monocytes, NK cells, and lymphocytes is different in preeclamptic patients as compared with normal pregnant womenAngelique L Veenstra van Nieuwenhoven
Department of Obstetrics and Gynecology, University Medical Centre Groningen, Groningen, The Netherlands
Hypertens Pregnancy 27:207-24. 2008..To measure cytokine production in ex vivo stimulated leukocyte populations of women with normal pregnancy and those with preeclampsia... - Towards stem-cell therapy in the endocrine pancreasShanti T Gangaram-Panday
Transplantation Biology and Immunoendocrinology, Section of Medical Biology, Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Groningen, The Netherlands
Trends Mol Med 13:164-73. 2007.... - Absence of in vivo generalized pro-inflammatory endothelial activation in severe, early-onset preeclampsiaRogier B Donker
Department of Obstetrics and Gynecology, Groningen University Institute for Drug Exploration, University Medical Center Groningen, Groningen, The Netherlands
J Soc Gynecol Investig 12:518-28. 2005..Therefore, this study aimed to investigate the presence of generalized proinflammatory endothelial activation in severe, early-onset preeclampsia in vivo... - Alginate-based microcapsules for immunoisolation of pancreatic isletsPaul De Vos
Department of Pathology and Laboratory Medicine, Division of Medical Biology, University Hospital of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Biomaterials 27:5603-17. 2006..New approaches in which newly discovered inflammatory responses are silenced bring the technology of transplantation of immunoisolated cells close to clinical application... - Factors influencing insulin secretion from encapsulated isletsBart J de Haan
Immunoendocrinology, Department of Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Cell Transplant 12:617-25. 2003..We conclude that capsules containing small islets (90-120 microm) and a membrane with a lower permeability than routinely applied is preferred in order to obtain a graft with adequate glucose-induced insulin responses... - The effect of testosterone on cytokine production in the specific and non-specific immune responseElske Posma
Department of Obstetrics and Gynaecology, University Hospital Groningen, Groningen, The Netherlands
Am J Reprod Immunol 52:237-43. 2004.... - Altered monocyte function in experimental preeclampsia in the ratMarijke M Faas
Transplantation Biology and Immunoendocrinology, Division of Medical Biology, Department of Pathology and Laboratory Medicine, University of Groningen, Groningen, The Netherlands
Am J Obstet Gynecol 191:1192-8. 2004..Increased WBC counts and granulocyte numbers in these rats also point to an activated inflammatory response... - Factors influencing functional survival of microencapsulated islet graftsPaul De Vos
Transplantation Biology and Immunoendocrinology, Department of Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Cell Transplant 13:515-24. 2004..Our observations indicate that we should focus on reduction of macrophage activation and on improving the nutrition of encapsulated islets to prevent islet cell death... - Gender difference in the non-specific and specific immune response in humansAnnechien Bouman
Department of Obstetrics and Gynecology, University Hospital Groningen, Groningen, The Netherlands
Am J Reprod Immunol 52:19-26. 2004..The purpose of this present ex vivo study is to get insight in the sex differences of the basic non-specific and specific immune response... - Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycleAngelique L Veenstra van Nieuwenhoven
Department of Obstetrics and Gynecology, University Hospital, Groningen, The Netherlands
Fertil Steril 77:1032-7. 2002.... - Factors influencing isolation of functional pancreatic rat isletsBart J de Haan
Transplantation Biology and Immunoendocrinology, Pathology and Laboratory Medicine, Section of Medical Biology, University of Groningen, Groningen, The Netherlands
Pancreas 29:e15-22. 2004..Our observations indicate that strain and weight of the rat donor, the source of bovine serum albumin, and the culture conditions of islets are pertinent factors in efficacious isolation of islets... - Monocyte cytokine production during pregnancyMarijke M Faas
J Leukoc Biol 75:153-4; author reply 155-6. 2004 - Endotoxin-induced cytokine production of monocytes of third-trimester pregnant women compared with women in the follicular phase of the menstrual cycleAngelique L Veenstra van Nieuwenhoven
Department of Obstetrics and Gynecology, University Hospital Groningen, The Netherlands
Am J Obstet Gynecol 188:1073-7. 2003..Little is known about the function of the innate immune response during pregnancy. We therefore investigated monocyte cytokine production, as a measure of monocyte function, in pregnant women compared with nonpregnant women... - Chemistry and the biological response against immunoisolating alginate-polycation capsules of different compositionSara Ponce
Faculty of Pharmacy, Laboratory of Pharmacy and Pharmaceutical Technology, University of the Basque Country, Vitoria-Gasteiz, Spain
Biomaterials 27:4831-9. 2006..Our results suggest that PLL is the best option available and that we should avoid using PLO and PDL in its present form since it is our goals to produce capsules that lack overgrowth and do not induce an immunological response as such... - Zeta-potentials of alginate-PLL capsules: a predictive measure for biocompatibility?Paul De Vos
Department of Pathology and Laboratory Medicine, Section of Medical Biology, Division of Immunoendocrinology, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
J Biomed Mater Res A 80:813-9. 2007..Our results suggest that we should not only consider the capsule properties under physiological circumstances to explain bioincompatibility but also the capsule features during common pathophysiological situations...