Janine Doorduin

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. pmc [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Mol Imaging Biol 11:386-98. 2009
  2. doi request reprint Evaluation of [11C]-DAA1106 for imaging and quantification of neuroinflammation in a rat model of herpes encephalitis
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Nucl Med Biol 37:9-15. 2010
  3. doi request reprint Neuroinflammation in schizophrenia-related psychosis: a PET study
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Nucl Med 50:1801-7. 2009
  4. doi request reprint Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study
    Erik F J de Vries
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Nucl Med Biol 35:459-66. 2008
  5. doi request reprint 18F-FEAnGA for PET of β-glucuronidase activity in neuroinflammation
    Inês F Antunes
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 53:451-8. 2012
  6. ncbi request reprint Evaluation of [(11)C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation
    Erik F J de Vries
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Nucl Med Biol 35:35-42. 2008
  7. ncbi request reprint PET imaging of the peripheral benzodiazepine receptor: monitoring disease progression and therapy response in neurodegenerative disorders
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Curr Pharm Des 14:3297-315. 2008
  8. ncbi request reprint Synthesis and preliminary evaluation of (S)-[11C]-exaprolol, a novel beta-adrenoceptor ligand for PET
    Aren van Waarde
    Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Neurochem Int 52:729-33. 2008
  9. ncbi request reprint Cerebral adenosine A₁ receptors are upregulated in rodent encephalitis
    Soumen Paul
    University of Groningen, University Medical Center Groningen, Nuclear Medicine and Molecular Imaging, Hanzeplein 1, 9713GZ Groningen, The Netherlands
    Neuroimage 92:83-9. 2014
  10. doi request reprint In vivo imaging of brain estrogen receptors in rats: a 16α-18F-fluoro-17β-estradiol PET study
    Mohammed A Khayum
    Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 55:481-7. 2014

Collaborators

Detail Information

Publications11

  1. pmc [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Mol Imaging Biol 11:386-98. 2009
    ..In this study, we evaluated the PET tracers [(11)C]-DPA-713 and [(18)F]-DPA-714 as agents for imaging of activated microglia in a rat model of herpes encephalitis...
  2. doi request reprint Evaluation of [11C]-DAA1106 for imaging and quantification of neuroinflammation in a rat model of herpes encephalitis
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Nucl Med Biol 37:9-15. 2010
    ..As a potentially more sensitive PET tracer for neuroinflammation, [(11)C]-N-(2,5-dimethoxybenzyl)-N-(4-fluoro-2-phenoxyphenyl)-acetamide (DAA1106) was evaluated in a rat model of herpes encephalitis...
  3. doi request reprint Neuroinflammation in schizophrenia-related psychosis: a PET study
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Nucl Med 50:1801-7. 2009
    ....
  4. doi request reprint Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study
    Erik F J de Vries
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Nucl Med Biol 35:459-66. 2008
    ..To clarify whether Pgp is involved in the sensitizing effect of celecoxib, we investigated in vivo whether celecoxib is a substrate of Pgp and whether it can affect the efflux activity of the pump...
  5. doi request reprint 18F-FEAnGA for PET of β-glucuronidase activity in neuroinflammation
    Inês F Antunes
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 53:451-8. 2012
    ..In this study, we investigated whether the PET tracer (18)F-FEAnGA was able to detect β-glucuronidase release during neuroinflammation in a rat model of herpes encephalitis...
  6. ncbi request reprint Evaluation of [(11)C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation
    Erik F J de Vries
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Nucl Med Biol 35:35-42. 2008
    ..This study aims to investigate [(11)C]rofecoxib as a positron emission tomography (PET) tracer for COX-2 expression...
  7. ncbi request reprint PET imaging of the peripheral benzodiazepine receptor: monitoring disease progression and therapy response in neurodegenerative disorders
    Janine Doorduin
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Curr Pharm Des 14:3297-315. 2008
    ..The imaging studies published so far showed that the PBR can be an important target for monitoring disease progression, therapy response and determining the optimal drug dose...
  8. ncbi request reprint Synthesis and preliminary evaluation of (S)-[11C]-exaprolol, a novel beta-adrenoceptor ligand for PET
    Aren van Waarde
    Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Neurochem Int 52:729-33. 2008
    ..The observed inhibition of tracer uptake in lung, spleen and erythrocytes seems due to an interaction of propranolol with amine transporters rather than beta-adrenoceptors...
  9. ncbi request reprint Cerebral adenosine A₁ receptors are upregulated in rodent encephalitis
    Soumen Paul
    University of Groningen, University Medical Center Groningen, Nuclear Medicine and Molecular Imaging, Hanzeplein 1, 9713GZ Groningen, The Netherlands
    Neuroimage 92:83-9. 2014
    ..Both the quantitative PET data and immunohistochemical analysis indicate that A1Rs are upregulated in brain areas where active virus is present...
  10. doi request reprint In vivo imaging of brain estrogen receptors in rats: a 16α-18F-fluoro-17β-estradiol PET study
    Mohammed A Khayum
    Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 55:481-7. 2014
    ....
  11. doi request reprint Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells
    Oliver C Neels
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    Cancer Res 68:7183-90. 2008
    ..This could be a consequence of the serotonin saturation of BON cells in the in vivo model...