H Dolstra

Summary

Affiliation: University Medical Center Nijmegen
Country: The Netherlands

Publications

  1. pmc A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia
    H Dolstra
    Department of Hematology, University Hospital Nijmegen, 6500 HB Nijmegen, The Netherlands
    J Exp Med 189:301-8. 1999
  2. ncbi request reprint Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytes
    Harry Dolstra
    Central Hematology Laboratory, University Medical Center St Radboud, Geert Grooteplein 8, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur J Immunol 32:2748-58. 2002
  3. ncbi request reprint Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms
    F Maas
    Central Hematology Laboratory, University Medical Center St Radboud, Nijmegen, The Netherlands
    Leukemia 17:630-3. 2003
  4. ncbi request reprint TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells
    H Dolstra
    Department of Hematology, University Medical Center St Radboud, Nijmegen, The Netherlands
    Bone Marrow Transplant 27:1087-93. 2001
  5. ncbi request reprint Multiple myeloma patients receiving pre-emptive donor lymphocyte infusion after partial T-cell-depleted allogeneic stem cell transplantation show a long progression-free survival
    H Levenga
    Department of Hematology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands
    Bone Marrow Transplant 40:355-9. 2007
  6. ncbi request reprint Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms
    F Maas
    Central Hematology Laboratory, University Medical Center St Radboud, Nijmegen, The Netherlands
    Leukemia 17:621-9. 2003
  7. ncbi request reprint Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens
    Bjorn de Rijke
    Central Hematology Laboratory, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Immunol Methods 329:125-37. 2008
  8. pmc A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia
    Bjorn de Rijke
    Central Hematology Laboratory, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Clin Invest 115:3506-16. 2005
  9. ncbi request reprint Quantification of the HA-1 gene product at the RNA level; relevance for immunotherapy of hematological malignancies
    Martina Wilke
    Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
    Hematol J 4:315-20. 2003
  10. ncbi request reprint Generation of autologous cytotoxic and helper T-cell responses against the B-cell leukemia-associated antigen HB-1: relevance for precursor B-ALL-specific immunotherapy
    Bjorn de Rijke
    Central Hematology Laboratory and Department of Hematology, University Medical Center St Radboud, 6500 HB Nijmegen, The Netherlands
    Blood 102:2885-91. 2003

Collaborators

Detail Information

Publications15

  1. pmc A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia
    H Dolstra
    Department of Hematology, University Hospital Nijmegen, 6500 HB Nijmegen, The Netherlands
    J Exp Med 189:301-8. 1999
    ....
  2. ncbi request reprint Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytes
    Harry Dolstra
    Central Hematology Laboratory, University Medical Center St Radboud, Geert Grooteplein 8, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur J Immunol 32:2748-58. 2002
    ..HB-1 is the first human mHag described that induces bi-directional allogeneic CTL responses that may contribute to a specific graft-versus-leukemia response following allogeneic stem cell transplantation...
  3. ncbi request reprint Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms
    F Maas
    Central Hematology Laboratory, University Medical Center St Radboud, Nijmegen, The Netherlands
    Leukemia 17:630-3. 2003
  4. ncbi request reprint TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells
    H Dolstra
    Department of Hematology, University Medical Center St Radboud, Nijmegen, The Netherlands
    Bone Marrow Transplant 27:1087-93. 2001
    ..2(+) TCR gamma delta CTL. Such KIR-regulated CTL reactivity may have a role in the GVL response without affecting normal tissues of the host and leading to GVHD...
  5. ncbi request reprint Multiple myeloma patients receiving pre-emptive donor lymphocyte infusion after partial T-cell-depleted allogeneic stem cell transplantation show a long progression-free survival
    H Levenga
    Department of Hematology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands
    Bone Marrow Transplant 40:355-9. 2007
    ..Although myeloablative SCT in MM induces high toxicity, we show that the concept of T-cell depletion followed by pDLI is promising and needs to be investigated in a reduced-intensity conditioning setting...
  6. ncbi request reprint Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms
    F Maas
    Central Hematology Laboratory, University Medical Center St Radboud, Nijmegen, The Netherlands
    Leukemia 17:621-9. 2003
    ....
  7. ncbi request reprint Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens
    Bjorn de Rijke
    Central Hematology Laboratory, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Immunol Methods 329:125-37. 2008
    ..Application of these optimized molecular approaches will lead to more rapid and reliable molecular identification of hematopoietic-restricted mHAgs...
  8. pmc A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia
    Bjorn de Rijke
    Central Hematology Laboratory, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Clin Invest 115:3506-16. 2005
    ..These findings illustrate that the P2X5-encoded mHAg LRH-1 could be an attractive target for specific immunotherapy to treat hematological malignancies recurring after allogeneic stem cell transplantation...
  9. ncbi request reprint Quantification of the HA-1 gene product at the RNA level; relevance for immunotherapy of hematological malignancies
    Martina Wilke
    Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
    Hematol J 4:315-20. 2003
    ..Thus, the mHag HA-1 can function as an excellent target antigen for immunotherapy of hematological malignancies with no or low risk of GvHD...
  10. ncbi request reprint Generation of autologous cytotoxic and helper T-cell responses against the B-cell leukemia-associated antigen HB-1: relevance for precursor B-ALL-specific immunotherapy
    Bjorn de Rijke
    Central Hematology Laboratory and Department of Hematology, University Medical Center St Radboud, 6500 HB Nijmegen, The Netherlands
    Blood 102:2885-91. 2003
    ..These present data, that HB-1 induces both helper and cytotoxic T-cell responses, indicate that the HB-1 antigen is a candidate target to induce T-cell-mediated antitumor immunity in patients...
  11. ncbi request reprint Monitoring of developing graft-versus-host disease mediated by herpes simplex virus thymidine kinase gene-transduced T cells
    Sebastianus Kolen
    Department of Hematology, University Medical Center St Radboud, 6500 HB Nijmegen, The Netherlands
    Hum Gene Ther 14:341-51. 2003
    ..Furthermore, we showed the potential use to study specific cause-effect relationships in a broad range of animal and clinical studies involving genetically engineered cells...
  12. ncbi request reprint Biodistribution and retention time of retrovirally labeled T lymphocytes in mice is strongly influenced by the culture period before infusion
    Sebastianus Kolen
    Department of Hemotology, University Medical Center St Radboud, Nijmegen, The Netherlands
    J Immunother 25:385-95. 2002
    ..We showed that accurate monitoring of transferred cells is feasible, which may contribute to understanding response to adoptive immunotherapy...
  13. ncbi request reprint Cellular adoptive immunotherapy after allogeneic stem cell transplantation
    Anton V M B Schattenberg
    Department of Hematology and Central Hematology Laboratory, Radboud University Nijmegen Medical Centre, The Netherlands
    Curr Opin Oncol 17:617-21. 2005
    ..This review presents the role of donor lymphocyte infusion, natural killer cells, and dendritic cells in cellular immunotherapy after allogeneic stem cell transplantation...
  14. pmc Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations
    Eric Spierings
    Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
    PLoS Genet 3:e103. 2007
    ..Significant differences in minor H antigen frequencies were observed between the ethnic populations, some of which appeared to be geographically correlated...
  15. doi request reprint Expression of P2X5 in lymphoid malignancies results in LRH-1-specific cytotoxic T-cell-mediated lysis
    Ingrid M Overes
    Central Haematology Laboratory, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Br J Haematol 141:799-807. 2008
    ..These findings indicate that MiHA LRH-1 is a potential therapeutic target for cellular immunotherapy of lymphoid malignancies...