Amalia M Dolga

Summary

Affiliation: University of Groningen
Country: The Netherlands

Publications

  1. doi TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels
    Amalia M Dolga
    Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands
    J Neurochem 107:1158-67. 2008
  2. ncbi Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways
    Amalia M Dolga
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, Kerklaan 30, 9751 NN, Haren, The Netherlands
    J Alzheimers Dis 13:111-22. 2008
  3. doi Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction
    Amalia M Dolga
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, Haren, The Netherlands
    J Alzheimers Dis 17:327-36. 2009
  4. doi Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation
    Ingrid M Nijholt
    Department of Molecular Neurobiology, University of Groningen, 9750 AA, Haren, The Netherlands
    Cell Signal 20:1715-24. 2008
  5. doi KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation
    Maria M Alves
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hum Mol Genet 19:3642-51. 2010
  6. doi Inflammation and NF-kappaB in Alzheimer's disease and diabetes
    Ivica Granic
    Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands
    J Alzheimers Dis 16:809-21. 2009
  7. ncbi A-kinase anchoring protein 150 in the mouse brain is concentrated in areas involved in learning and memory
    Anghelus Ostroveanu
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands
    Brain Res 1145:97-107. 2007
  8. doi Statins: mechanisms of neuroprotection
    Peter J van der Most
    Department of Molecular Neurobiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    Prog Neurobiol 88:64-75. 2009
  9. doi Identification and characterization of a novel, shorter isoform of the small conductance Ca2+ -activated K+ channel SK2
    Saravana R K Murthy
    Max Planck Institute for Experimental Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96813, USA
    J Neurochem 106:2312-21. 2008

Collaborators

Detail Information

Publications9

  1. doi TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels
    Amalia M Dolga
    Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands
    J Neurochem 107:1158-67. 2008
    ..We conclude that treatment of primary cortical neurons with TNF-alpha leads to increased K(Ca)2.2 channel expression which renders neurons more resistant to excitotoxic cell death...
  2. ncbi Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways
    Amalia M Dolga
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, Kerklaan 30, 9751 NN, Haren, The Netherlands
    J Alzheimers Dis 13:111-22. 2008
    ..Thus, lovastatin-induced neuroprotection against glutamate-excitotoxicity via activation of TNF-R2-signaling pathways...
  3. doi Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction
    Amalia M Dolga
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, Haren, The Netherlands
    J Alzheimers Dis 17:327-36. 2009
    ..From these studies we conclude that treatment with lovastatin may provide protection against neuronal injury in excitotoxic conditions associated with neurodegenerative diseases including Alzheimer's disease...
  4. doi Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation
    Ingrid M Nijholt
    Department of Molecular Neurobiology, University of Groningen, 9750 AA, Haren, The Netherlands
    Cell Signal 20:1715-24. 2008
    ..From experiments using PKA-binding deficient AKAP150 and peptides disrupting PKA anchoring to AKAPs, we conclude that AKAP150 acts as a key regulator in the two cAMP pathways to control PKB/Akt phosphorylation...
  5. doi KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation
    Maria M Alves
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Hum Mol Genet 19:3642-51. 2010
    ..Thus, our data indicate that KBP is involved in neuronal differentiation and that the central and enteric nervous system defects seen in GOSHS are likely caused by microtubule-related defects...
  6. doi Inflammation and NF-kappaB in Alzheimer's disease and diabetes
    Ivica Granic
    Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands
    J Alzheimers Dis 16:809-21. 2009
    ..Here, we review the literature on how inflammation and the inducible nuclear factor NF-kappaB might be involved in both diabetes mellitus and Alzheimer's disease and whether these factors can link both diseases...
  7. ncbi A-kinase anchoring protein 150 in the mouse brain is concentrated in areas involved in learning and memory
    Anghelus Ostroveanu
    Department of Molecular Neurobiology, Graduate School of Behavioral and Cognitive Neurosciences, University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands
    Brain Res 1145:97-107. 2007
    ..In general we observed that AKAP150 is strongly expressed in mouse brain regions involved in learning and memory. These data support its suggested role in synaptic plasticity and memory processes...
  8. doi Statins: mechanisms of neuroprotection
    Peter J van der Most
    Department of Molecular Neurobiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    Prog Neurobiol 88:64-75. 2009
    ..The final section deals with the effects of statins on the central nervous system, particularly during Alzheimer's and Parkinson's disease, stroke and multiple sclerosis...
  9. doi Identification and characterization of a novel, shorter isoform of the small conductance Ca2+ -activated K+ channel SK2
    Saravana R K Murthy
    Max Planck Institute for Experimental Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96813, USA
    J Neurochem 106:2312-21. 2008
    ..Thus, SK2-sh as a downstream target of cytokines, provide a promising target for additional investigation regarding potential therapeutic intervention...