Karina de Leeuw

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. pmc Increased B-type natriuretic peptide and decreased proteinuria might reflect decreased capillary leakage and is associated with a better outcome in patients with severe burns
    Karina de Leeuw
    Department of Internal Medicine, Martini Hospital, van Swietenplein 1, 9700 RM Groningen, The Netherlands
    Crit Care 15:R161. 2011
  2. ncbi request reprint Accelerated atherosclerosis in patients with systemic autoimmune diseases
    Karina de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Hospital, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Ann N Y Acad Sci 1051:362-71. 2005
  3. doi request reprint Longitudinal study on premature atherosclerosis in patients with systemic lupus erythematosus
    Karina de Leeuw
    Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Atherosclerosis 206:546-50. 2009
  4. doi request reprint Skin capillary permeability in the diabetic foot with critical limb ischaemia: the effects of a phVEGF165 gene product
    K de Leeuw
    Department of Internal Medicine, Divisions of Rheumatology and Clinical Immunology, University Medical Center, Groningen, Groningen, The Netherlands
    Diabet Med 25:1241-4. 2008
  5. doi request reprint Vascular responsiveness in the microcirculation of patients with systemic lupus erythematosus is not impaired
    K de Leeuw
    Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, University Medical Center, Groningen, The Netherlands
    Lupus 17:1010-7. 2008
  6. ncbi request reprint "Acute liver failure": the heart may be the matter
    K de Leeuw
    Department of Internal Medicine, Division of Rheumatology and Clinical Immunology, University Medical Centre Groningen, The Netherlands
    Acta Clin Belg 66:236-9. 2011
  7. ncbi request reprint Accumulation of advanced glycation endproducts in patients with systemic lupus erythematosus
    K de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Medical Centre Groningen, Groningen, The Netherlands
    Rheumatology (Oxford) 46:1551-6. 2007
  8. ncbi request reprint Traditional and non-traditional risk factors contribute to the development of accelerated atherosclerosis in patients with systemic lupus erythematosus
    K de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Lupus 15:675-82. 2006
  9. ncbi request reprint Patients with Wegener's granulomatosis: a long-term follow-up study
    Karina de Leeuw
    Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, The Netherlands
    Clin Exp Rheumatol 28:18-23. 2010
  10. ncbi request reprint Enhanced endothelium-dependent microvascular responses in patients with Wegener's granulomatosis
    Hans L A Nienhuis
    Department of Internal Medicine, Division of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Rheumatol 34:1875-81. 2007

Collaborators

Detail Information

Publications15

  1. pmc Increased B-type natriuretic peptide and decreased proteinuria might reflect decreased capillary leakage and is associated with a better outcome in patients with severe burns
    Karina de Leeuw
    Department of Internal Medicine, Martini Hospital, van Swietenplein 1, 9700 RM Groningen, The Netherlands
    Crit Care 15:R161. 2011
    ..This study investigates whether combining BNP and proteinuria can be used as a guide for individualized resuscitation and as a predictor of outcome in patients with severe burns...
  2. ncbi request reprint Accelerated atherosclerosis in patients with systemic autoimmune diseases
    Karina de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Hospital, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Ann N Y Acad Sci 1051:362-71. 2005
    ..This review updates information on the factors that contribute to accelerated atherosclerosis in patients with systemic autoimmune diseases, such as disease-related factors, inflammatory mediators, and advanced glycation end products...
  3. doi request reprint Longitudinal study on premature atherosclerosis in patients with systemic lupus erythematosus
    Karina de Leeuw
    Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Atherosclerosis 206:546-50. 2009
    ..To determine risk factors of accelerated atherosclerosis and progression of intima-media thickness (IMT) in patients with systemic lupus erythematosus (SLE)...
  4. doi request reprint Skin capillary permeability in the diabetic foot with critical limb ischaemia: the effects of a phVEGF165 gene product
    K de Leeuw
    Department of Internal Medicine, Divisions of Rheumatology and Clinical Immunology, University Medical Center, Groningen, Groningen, The Netherlands
    Diabet Med 25:1241-4. 2008
    ....
  5. doi request reprint Vascular responsiveness in the microcirculation of patients with systemic lupus erythematosus is not impaired
    K de Leeuw
    Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, University Medical Center, Groningen, The Netherlands
    Lupus 17:1010-7. 2008
    ..Therefore, LDF of the microcirculation seems not to be the appropriate method to distinguish those SLE patients with an increased risk to develop CVD...
  6. ncbi request reprint "Acute liver failure": the heart may be the matter
    K de Leeuw
    Department of Internal Medicine, Division of Rheumatology and Clinical Immunology, University Medical Centre Groningen, The Netherlands
    Acta Clin Belg 66:236-9. 2011
    ..In conclusion, when the cause of acute liver dysfunction is unclear, hypoxic hepatitis due to heart failure should be considered and echocardiography should be performed, even when symptoms are non-specific for heart failure...
  7. ncbi request reprint Accumulation of advanced glycation endproducts in patients with systemic lupus erythematosus
    K de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Medical Centre Groningen, Groningen, The Netherlands
    Rheumatology (Oxford) 46:1551-6. 2007
    ....
  8. ncbi request reprint Traditional and non-traditional risk factors contribute to the development of accelerated atherosclerosis in patients with systemic lupus erythematosus
    K de Leeuw
    Department of Internal Medicine, Division of Clinical Immunology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Lupus 15:675-82. 2006
    ..Non-traditional risk factors, such as endothelial activation, altered vascular remodelling and disease duration, might play an additional role...
  9. ncbi request reprint Patients with Wegener's granulomatosis: a long-term follow-up study
    Karina de Leeuw
    Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, The Netherlands
    Clin Exp Rheumatol 28:18-23. 2010
    ..Atherosclerosis is accelerated in Wegener's granulomatosis (WG) patients. This study was aimed to assess which factors can predict progression of atherosclerosis in WG...
  10. ncbi request reprint Enhanced endothelium-dependent microvascular responses in patients with Wegener's granulomatosis
    Hans L A Nienhuis
    Department of Internal Medicine, Division of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Rheumatol 34:1875-81. 2007
    ..To assess endothelial cell (EC) function of the cutaneous microcirculation in patients with Wegener's granulomatosis (WG) and to relate EC function to EC activation and presence of atherosclerosis...
  11. pmc Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness
    Hans L A Nienhuis
    Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, 9713 GZ, The Netherlands
    Arthritis Res Ther 12:R181. 2010
    ....
  12. pmc Early atherosclerosis in systemic sclerosis and its relation to disease or traditional risk factors
    Martha E Hettema
    Department of Internal Medicine, Division of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30, 001, 9700 RB Groningen, The Netherlands
    Arthritis Res Ther 10:R49. 2008
    ..We compared patients with SSc to healthy controls for signs of early atherosclerosis by measuring intima-media thickness (IMT) of the common carotid artery in relation to traditional risk factors and markers of endothelial activation...
  13. pmc Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus
    Jan Renier A J Moonen
    Department of Pathology and Laboratory Medicine, University Medical Center Groningen, University of Groningen, The Netherlands
    Arthritis Res Ther 9:R84. 2007
    ..003). We conclude that CPC numbers are reduced in SLE patients and functionality is partly impaired. We suggest these findings reflect increased susceptibility to apoptosis of CPCs from SLE patients...
  14. ncbi request reprint Skin autofluorescence is elevated in patients with stable coronary artery disease and is associated with serum levels of neopterin and the soluble receptor for advanced glycation end products
    Douwe J Mulder
    Department of Internal Medicine, University Medical Center Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Atherosclerosis 197:217-23. 2008
    ....
  15. pmc Standardised assessment of membrane proteinase 3 expression. Analysis in ANCA-associated vasculitis and controls
    Andre P van Rossum
    Department of Rheumatology and Clinical Immunology, Groningen University Medical Centre, University of Groningen, The Netherlands
    Ann Rheum Dis 66:1350-5. 2007
    ..Using neutrophils before and after priming with TNFalpha, we assessed percentages of mPR3(+) neutrophils in patients with AAV and in disease and healthy controls...