Research Topics
Species | E CorpeleijnSummaryAffiliation: University Medical Center Groningen Country: The Netherlands Publications
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Detail Information
Publications
Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyleE Corpeleijn
Department of Human Biology, The Nutrition and Toxicology Research Institute NUTRIM, Maastricht University, Maastricht, The Netherlands
Obes Rev 10:178-93. 2009..Lifestyle changes in dietary fat intake, physical activity and weight loss may improve metabolic flexibility in skeletal muscle, and thereby contribute to the prevention of type 2 diabetes...
Oxidation of intramyocellular lipids is dependent on mitochondrial function and the availability of extracellular fatty acidsEva Corpeleijn
Department of Human Biology, Maastricht University, Nutrition and Toxicology Research Institute Maastricht, Maastricht, The Netherlands
Am J Physiol Endocrinol Metab 299:E14-22. 2010..02). In conclusion, the rate of ICL(OX) is dependent on the availability of extracellular fatty acids and mitochondrial function rather than mitochondrial mass...
Predictors of lifestyle intervention outcome and dropout: the SLIM studyC Roumen
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, NUTRIM, Maastricht University, Maastricht, The Netherlands
Eur J Clin Nutr 65:1141-7. 2011..To evaluate the effect of a 4.1-year (range 3-6 years) lifestyle intervention according to general public health recommendations on glucose tolerance and dropout in a Dutch population with impaired glucose tolerance (IGT)...
Impact of 3-year lifestyle intervention on postprandial glucose metabolism: the SLIM studyC Roumen
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, NUTRIM, Maastricht University, Maastricht, The Netherlands
Diabet Med 25:597-605. 2008....
Insulin acutely upregulates protein expression of the fatty acid transporter CD36 in human skeletal muscle in vivoE Corpeleijn
From the Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
J Physiol Pharmacol 59:77-83. 2008..We conclude that also in obese humans the FAT/CD36 protein content in skeletal muscle is dynamically regulated by insulin in vivo on the short term...
Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistanceE Corpeleijn
Department of Medicine and Endocrinology, Cardiovascular Research Institute CARIM, University Hospital Maastricht, Maastricht, The Netherlands
Diabet Med 23:907-11. 2006..Genetic variation in the CD36 gene may contribute to the aetiology of diabetes...
Expression of genes involved in lipid metabolism in men with impaired glucose tolerance: impact of insulin stimulation and weight lossE Konings
Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands
J Nutrigenet Nutrigenomics 3:9-17. 2010..Conclusions:SREBP-2 shows altered insulin responsiveness in IGT men compared with NGT men, while there were no differences in basal gene expression...
Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities: the SLIM studyE Corpeleijn
Department of Human Biology, The Nutrition and Toxicology Research Institute NUTRIM, Maastricht University, Maastricht, The Netherlands
Diabetologia 49:2392-401. 2006....
