W Cahn

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi Brain morphology in antipsychotic-naïve schizophrenia: a study of multiple brain structures
    W Cahn
    Department of Psychiatry, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Br J Psychiatry Suppl 43:s66-72. 2002
  2. doi Brain volume reductions in medication-naive patients with schizophrenia in relation to intelligence quotient
    M Rais
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychol Med 42:1847-56. 2012
  3. doi Psychosis and brain volume changes during the first five years of schizophrenia
    W Cahn
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 19:147-51. 2009
  4. doi Cigarette smoking and progressive brain volume loss in schizophrenia
    N E M Van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, The Netherlands
    Eur Neuropsychopharmacol 20:454-8. 2010
  5. doi Symptom dimensions are associated with progressive brain volume changes in schizophrenia
    G Collin
    University Medical Center Utrecht, Department of Psychiatry, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Schizophr Res 138:171-6. 2012
  6. doi Schizophrenia as a progressive brain disease
    N E M Van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Eur Psychiatry 23:245-54. 2008
  7. ncbi Brain volume changes in the first year of illness and 5-year outcome of schizophrenia
    W Cahn
    Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584 GX Utrecht, The Netherlands
    Br J Psychiatry 189:381-2. 2006
  8. doi Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial
    T W Scheewe
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Acta Psychiatr Scand 127:464-73. 2013
  9. doi The course of brain abnormalities in schizophrenia: can we slow the progression?
    N E van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Psychopharmacol 26:8-14. 2012
  10. doi The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder
    H van Welie
    Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands
    Schizophr Res 143:354-7. 2013

Collaborators

Detail Information

Publications17

  1. ncbi Brain morphology in antipsychotic-naïve schizophrenia: a study of multiple brain structures
    W Cahn
    Department of Psychiatry, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Br J Psychiatry Suppl 43:s66-72. 2002
    ..Although brain volume changes are found in schizophrenia, only a limited number of structural magnetic resonance imaging studies have exclusively examined antipsychotic-naïve patients...
  2. doi Brain volume reductions in medication-naive patients with schizophrenia in relation to intelligence quotient
    M Rais
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Psychol Med 42:1847-56. 2012
    ..Whether these changes are dependent on medication use or related to intelligence quotient (IQ) is still debated...
  3. doi Psychosis and brain volume changes during the first five years of schizophrenia
    W Cahn
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 19:147-51. 2009
    ..These findings strongly suggest that psychosis contributes to brain volume reductions found in schizophrenia...
  4. doi Cigarette smoking and progressive brain volume loss in schizophrenia
    N E M Van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, The Netherlands
    Eur Neuropsychopharmacol 20:454-8. 2010
    ..Moreover, smoking was not associated with brain volume change over time in the healthy subjects. However, extremely heavy smoking may contribute to excessive gray matter volume loss in schizophrenia...
  5. doi Symptom dimensions are associated with progressive brain volume changes in schizophrenia
    G Collin
    University Medical Center Utrecht, Department of Psychiatry, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Schizophr Res 138:171-6. 2012
    ..e. negative, positive, disorganization, mania and depression)...
  6. doi Schizophrenia as a progressive brain disease
    N E M Van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Eur Psychiatry 23:245-54. 2008
    ..One of the main challenges for the coming years, however, will be the search for gene-by-environment interactions on the progressive brain changes in schizophrenia...
  7. ncbi Brain volume changes in the first year of illness and 5-year outcome of schizophrenia
    W Cahn
    Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584 GX Utrecht, The Netherlands
    Br J Psychiatry 189:381-2. 2006
    ..These findings suggest that early dynamic brain volume changes are related to the disease process and predict the longer-term outcome of schizophrenia...
  8. doi Exercise therapy improves mental and physical health in schizophrenia: a randomised controlled trial
    T W Scheewe
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Acta Psychiatr Scand 127:464-73. 2013
    ..The objective of this multicenter randomised clinical trial was to examine the effect of exercise versus occupational therapy on mental and physical health in schizophrenia patients...
  9. doi The course of brain abnormalities in schizophrenia: can we slow the progression?
    N E van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Psychopharmacol 26:8-14. 2012
    ..Before being able to intervene with therapies and prevent the brain from shrinking, one has to understand the underlying mechanism of the progressive changes in the brains of schizophrenia patients...
  10. doi The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder
    H van Welie
    Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands
    Schizophr Res 143:354-7. 2013
    ..6%, OR=1.6, p=0.007). Our findings support the hypothesis of a familial, possibly genetic, link between DM and non-affective psychotic disorders...
  11. doi Confounders of excessive brain volume loss in schizophrenia
    N E van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, The Netherlands Electronic address
    Neurosci Biobehav Rev 37:2418-23. 2013
    ..Atypical antipsychotics have been found to be related to smaller decreases in tissue loss. Moreover, independent of antipsychotic medication intake, the brain volume abnormalities appear associated to the outcome of the illness...
  12. doi Schizophrenia genetic variants are not associated with intelligence
    A F Terwisscha van Scheltinga
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Psychol Med 43:2563-70. 2013
    ..Therefore, we hypothesized that genetic variants associated with schizophrenia, including copy number variants (CNVs) and a polygenic schizophrenia (risk) score (PSS), may influence intelligence...
  13. ncbi Excessive recruitment of neural systems subserving logical reasoning in schizophrenia
    N F Ramsey
    Functional Imaging Section, Department of Psychiatry, University Medical Center of Utrecht, Utrecht, The Netherlands
    Brain 125:1793-807. 2002
    ..The reported association between performance and brain activity is relevant to clinical imaging studies in general...
  14. doi Age at onset of non-affective psychosis in relation to cannabis use, other drug use and gender
    N Dekker
    Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Psychol Med 42:1903-11. 2012
    ..The aim of the present study was to examine whether this association is confounded by gender or other substance use in a large cohort of patients with a non-affective psychotic disorder...
  15. ncbi CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy
    J I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Mol Psychiatry 13:261-6. 2008
    ..Our data thus confirm an association of CNTNAP2 to epilepsy outside the Old Order Amish population and suggest that dosage alteration of this gene may lead to a complex phenotype of schizophrenia, epilepsy and cognitive impairment...
  16. ncbi Cannabis and brain morphology in recent-onset schizophrenia
    W Cahn
    Schizophr Res 67:305-7. 2004
  17. ncbi Focal white matter density changes in schizophrenia: reduced inter-hemispheric connectivity
    Hilleke E Hulshoff Pol
    Neuroscience Division, A01 126, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands
    Neuroimage 21:27-35. 2004
    ..These findings suggest aberrant inter-hemispheric connectivity of anterior cortical and sub-cortical brain regions in schizophrenia, reflecting decreased hemispheric specialisation in schizophrenia...