B M Th Burgering

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Mdm2 induces mono-ubiquitination of FOXO4
    Arjan B Brenkman
    Department of Physiological Chemistry and Centre for Biomedical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 3:e2819. 2008
  2. pmc Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
    Astrid Eijkelenboom
    Department of Molecular Cancer Research, University Medical Centre, Utrecht, The Netherlands
    Mol Syst Biol 9:638. 2013
  3. doi request reprint A brief introduction to FOXOlogy
    B M Th Burgering
    Laboratory of Physiological Chemistry, University Medical Center Utrecht, Stratenum, Utrecht, The Netherlands
    Oncogene 27:2258-62. 2008

Collaborators

Detail Information

Publications3

  1. pmc Mdm2 induces mono-ubiquitination of FOXO4
    Arjan B Brenkman
    Department of Physiological Chemistry and Centre for Biomedical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS ONE 3:e2819. 2008
    ..For example, the de-ubiquitinating enzyme USP7 removes ubiquitin from both FOXO and p53. However, Skp2 has been identified as E3 ligase for FOXO1, whereas Mdm2 is the prime E3 ligase for p53...
  2. pmc Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
    Astrid Eijkelenboom
    Department of Molecular Cancer Research, University Medical Centre, Utrecht, The Netherlands
    Mol Syst Biol 9:638. 2013
    ..Combined, our data elucidate how FOXOs regulate gene transcription and provide insight into mechanisms by which FOXOs can induce different gene expression programs depending on chromatin architecture...
  3. doi request reprint A brief introduction to FOXOlogy
    B M Th Burgering
    Laboratory of Physiological Chemistry, University Medical Center Utrecht, Stratenum, Utrecht, The Netherlands
    Oncogene 27:2258-62. 2008
    ..With this perspective, further studies on FOXO function and regulation may shed light on how age impacts on the onset and progression of disease...