J Peter H Burbach
Affiliation: University Medical Center Utrecht
Country: The Netherlands
Burbach J, Hellemons A, Grant P, Pant H. The homeodomain transcription factor Phox2 in the stellate ganglion of the squid Loligo pealei. Biol Open. 2015;4:954-60 pubmed publisher
..Furthermore, the Fmrf upstream region contained putative Phox2a/b binding sites. These results suggest a role of lpPhox2 in the developmental specification of neuronal identity and regulation of neurons of the squid giant axon. ..
Oguro Ando A, Zuko A, Kleijer K, Burbach J. A current view on contactin-4, -5, and -6: Implications in neurodevelopmental disorders. Mol Cell Neurosci. 2017;81:72-83 pubmed publisher
..Finally, we highlight to role of protein-protein interactions in the potential mechanism of action of Cntn4, -5 and -6 and emphasize that complexes with other membrane proteins may play a role in neuronal developmental functions. ..
Kleijer K, Zuko A, Shimoda Y, Watanabe K, Burbach J. Contactin-5 expression during development and wiring of the thalamocortical system. Neuroscience. 2015;310:106-13 pubmed publisher
..Subtle alterations in the formation of the thalamocortical circuit may contribute to neurodevelopmental disorders, such as ASD. ..
Kleijer K, Huguet G, Tastet J, Bourgeron T, Burbach J. Anatomy and Cell Biology of Autism Spectrum Disorder: Lessons from Human Genetics. Adv Anat Embryol Cell Biol. 2017;224:1-25 pubmed publisher
..These current insights should lead to a rational design of interventions in molecular and cellular pathways of ASD pathogenesis that may be applied to affected individuals in the future. ..