Annelien L Bredenoord

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. doi request reprint Nuclear transfer to prevent mitochondrial DNA disorders: revisiting the debate on reproductive cloning
    A L Bredenoord
    Maastricht University and University Medical Center, Utrecht, The Netherlands
    Reprod Biomed Online 22:200-7. 2011
  2. doi request reprint Ethics of intergenerational (father-to-son) sperm donation
    Annelien L Bredenoord
    Julius Center, Department of Medical Ethics, University Medical Center Utrecht, Stratenum 6 131, 3508 GA Utrecht, The Netherlands
    Hum Reprod 27:1286-91. 2012
  3. doi request reprint Ethics of modifying the mitochondrial genome
    A L Bredenoord
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum, 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Med Ethics 37:97-100. 2011
  4. pmc Preimplantation genetic diagnosis for mitochondrial DNA disorders: ethical guidance for clinical practice
    Annelien Bredenoord
    Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Eur J Hum Genet 17:1550-9. 2009
  5. doi request reprint Reproductive decision-making in the context of mitochondrial DNA disorders: views and experiences of professionals
    A L Bredenoord
    Maastricht University, Faculty of Health, Medicine and Life Sciences, Health, Ethics and Society, Research Institutes GROW and CAPHRI, Maastricht, The Netherlands
    Clin Genet 77:10-7. 2010
  6. doi request reprint Avoiding transgenerational risks of mitochondrial DNA disorders: a morally acceptable reason for sex selection?
    Annelien L Bredenoord
    Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Research Institute GROW and CAPHRI, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Hum Reprod 25:1354-60. 2010
  7. doi request reprint Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy
    Annelien L Bredenoord
    Department of Medical Ethics, University Medical Center Utrecht, Division Julius Center, Utrecht, The Netherlands
    Hum Mutat 32:861-7. 2011
  8. doi request reprint Disclosure of individual genetic data to research participants: the debate reconsidered
    Annelien L Bredenoord
    University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Department of Medical Ethics, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Trends Genet 27:41-7. 2011
  9. pmc Inclusion of residual tissue in biobanks: opt-in or opt-out?
    Noor A A Giesbertz
    Department of Medical Humanities, Julius Center, University Medical Center Utrecht, The Netherlands
    PLoS Biol 10:e1001373. 2012
  10. doi request reprint Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology
    Martijn P Lolkema
    University Medical Center Utrecht, The Netherlands
    J Clin Oncol 31:1842-8. 2013

Collaborators

Detail Information

Publications13

  1. doi request reprint Nuclear transfer to prevent mitochondrial DNA disorders: revisiting the debate on reproductive cloning
    A L Bredenoord
    Maastricht University and University Medical Center, Utrecht, The Netherlands
    Reprod Biomed Online 22:200-7. 2011
    ..Nevertheless, as it may lead to more complex ethical appraisals than the other variants, researchers should initially focus on the development of the other types of nuclear transfer to prevent mtDNA disorders...
  2. doi request reprint Ethics of intergenerational (father-to-son) sperm donation
    Annelien L Bredenoord
    Julius Center, Department of Medical Ethics, University Medical Center Utrecht, Stratenum 6 131, 3508 GA Utrecht, The Netherlands
    Hum Reprod 27:1286-91. 2012
    ..We will conclude the paper with recommendations for a morally sound practice of IMAR...
  3. doi request reprint Ethics of modifying the mitochondrial genome
    A L Bredenoord
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum, 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Med Ethics 37:97-100. 2011
    ..If nuclear transfer to prevent mtDNA disorders becomes safe and effective, then dismissing it because it involves germ-line modification is unjustified...
  4. pmc Preimplantation genetic diagnosis for mitochondrial DNA disorders: ethical guidance for clinical practice
    Annelien Bredenoord
    Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Eur J Hum Genet 17:1550-9. 2009
    ..Fifth, we discuss whether follow-up studies should be conducted, particularly the genetic testing of children born after IVF/PGD. Finally, we offer the main information that is required to obtain a truly informed consent...
  5. doi request reprint Reproductive decision-making in the context of mitochondrial DNA disorders: views and experiences of professionals
    A L Bredenoord
    Maastricht University, Faculty of Health, Medicine and Life Sciences, Health, Ethics and Society, Research Institutes GROW and CAPHRI, Maastricht, The Netherlands
    Clin Genet 77:10-7. 2010
    ..Insight into the experiences of professionals may contribute to a further improvement of reproductive genetic counseling in the context of mtDNA disorders...
  6. doi request reprint Avoiding transgenerational risks of mitochondrial DNA disorders: a morally acceptable reason for sex selection?
    Annelien L Bredenoord
    Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Research Institute GROW and CAPHRI, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Hum Reprod 25:1354-60. 2010
    ..To start an IVF/PGD-cycle especially for this purpose would be disproportional. The alternative approach of preconceptional sex selection may be morally justified as a means to increase the chances of obtaining male embryos...
  7. doi request reprint Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy
    Annelien L Bredenoord
    Department of Medical Ethics, University Medical Center Utrecht, Division Julius Center, Utrecht, The Netherlands
    Hum Mutat 32:861-7. 2011
    ..We appeal to the genetics community to make a joint effort to further refine the packages and set thresholds for result selection...
  8. doi request reprint Disclosure of individual genetic data to research participants: the debate reconsidered
    Annelien L Bredenoord
    University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Department of Medical Ethics, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Trends Genet 27:41-7. 2011
    ....
  9. pmc Inclusion of residual tissue in biobanks: opt-in or opt-out?
    Noor A A Giesbertz
    Department of Medical Humanities, Julius Center, University Medical Center Utrecht, The Netherlands
    PLoS Biol 10:e1001373. 2012
    ..We suggest that further interdisciplinary debate should answer the question when to opt-in or when to opt-out...
  10. doi request reprint Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology
    Martijn P Lolkema
    University Medical Center Utrecht, The Netherlands
    J Clin Oncol 31:1842-8. 2013
    ..We also provide a framework for returning these genetic results by proposing a design for a qualified disclosure policy...
  11. doi request reprint Ooplasmic and nuclear transfer to prevent mitochondrial DNA disorders: conceptual and normative issues
    A L Bredenoord
    Maastricht University, Health, Ethics and Society and Research Institute GROW, Maastricht, The Netherlands
    Hum Reprod Update 14:669-78. 2008
    ..Both OT and NT are radical in the sense that they do not entail genetic selection, but genetic intervention to correct the genetic cause of the disease...
  12. doi request reprint PGD to reduce reproductive risk: the case of mitochondrial DNA disorders
    A L Bredenoord
    Maastricht University, Health, Ethics and Society, Maastricht, The Netherlands
    Hum Reprod 23:2392-401. 2008
    ..Nevertheless, introducing this new application of PGD in clinical practice will raise further complex issues of determining conditions for its responsible use...
  13. ncbi request reprint Dealing with uncertainties: ethics of prenatal diagnosis and preimplantation genetic diagnosis to prevent mitochondrial disorders
    A L Bredenoord
    Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands
    Hum Reprod Update 14:83-94. 2008
    ....