Research Topics
| Matthijs G BossongSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Delta 9-tetrahydrocannabinol induces dopamine release in the human striatumMatthijs G Bossong
Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Neuropsychopharmacology 34:759-66. 2009..Further, it implies that the endogenous cannabinoid system is involved in regulating striatal dopamine release. This allows new directions in research on the effects of THC in neuropsychiatric disorders, such as schizophrenia...
mCPP: an undesired addition to the ecstasy marketM G Bossong
Drug Information and Monitoring System DIMS, Trimbos Institute for Mental Health and Addiction, Utrecht, The Netherlands
J Psychopharmacol 24:1395-401. 2010..In addition, the reports of users concerning the effects of mCPP are predominantly negative. All these aspects together lead to the conclusion that mCPP is an undesired addition to the ecstasy market from the user's perspective...
Effects of Δ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI studyMatthijs G Bossong
University Medical Center Utrecht, The Netherlands
J Cogn Neurosci 24:588-99. 2012..These results further emphasize the eCB system as a potential novel target for treatment of memory disorders and a promising target for development of new therapies to reduce memory deficits in humans...
Evidence for involvement of the insula in the psychotropic effects of THC in humans: a double-blind, randomized pharmacological MRI studyHendrika H Van Hell
Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands
Int J Neuropsychopharmacol 14:1377-88. 2011..These changes may represent the THC-induced neurophysiological correlates of feeling high. The alterations in baseline brain perfusion and activity also have relevance for studies on task-related effects of THC on brain function...
Effects of δ9-tetrahydrocannabinol on human working memory functionMatthijs G Bossong
Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
Biol Psychiatry 71:693-9. 2012..These findings suggest the possibility that the eCB system is also involved in WM deficits in schizophrenia. In the present study, we examined if perturbation of the eCB system can induce abnormal WM activity in healthy subjects...
Involvement of the endocannabinoid system in reward processing in the human brainHendrika H Van Hell
Department of Neurology and Neurosurgery, G 03 124, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Psychopharmacology (Berl) 219:981-90. 2012..The endocannabinoid (eCB) system has been implicated in reward processing in animals, but in humans, the relation between eCB functioning and reward is less clear...
Methods of the pharmacological imaging of the cannabinoid system (PhICS) study: towards understanding the role of the brain endocannabinoid system in human cognitionHendrika H Van Hell
Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
Int J Methods Psychiatr Res 20:10-27. 2011....
Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophreniaMatthijs G Bossong
Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Prog Neurobiol 92:370-85. 2010....
Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography studyBart N Van Berckel
Department of Psychiatry, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Biol Psychiatry 64:820-2. 2008..Microglia activation can be quantified in vivo using (R)-[(11)C]PK11195 and positron emission tomography (PET). The purpose of this study was to investigate whether microglia activation occurs in patients with recent-onset schizophrenia...
