Marinus A J Borgdorff

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. doi request reprint Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children s Hospital, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands
    Eur J Heart Fail 14:1067-74. 2012
  2. doi request reprint Distinct loading conditions reveal various patterns of right ventricular adaptation
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, Groningen, The Netherlands
    Am J Physiol Heart Circ Physiol 305:H354-64. 2013
  3. ncbi request reprint A cornerstone of heart failure treatment is not effective in experimental right ventricular failure
    Marinus A Borgdorff
    Center For Congenital Heart Diseases, Pediatric Cardiology, Beatrix Children s Hospital, University of Groningen, University Medical Center Groningen, The Netherlands Electronic address
    Int J Cardiol 169:183-9. 2013
  4. doi request reprint The role of disturbed blood flow in the development of pulmonary arterial hypertension: lessons from preclinical animal models
    Michael G Dickinson
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 305:L1-14. 2013

Detail Information

Publications4

  1. doi request reprint Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children s Hospital, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands
    Eur J Heart Fail 14:1067-74. 2012
    ..We aimed to demonstrate that the phosphodiesterase 5A inhibitor sildenafil can prevent adverse remodelling and improve function in chronic abnormal RV overload, independent from effects on the pulmonary vasculature...
  2. doi request reprint Distinct loading conditions reveal various patterns of right ventricular adaptation
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, Groningen, The Netherlands
    Am J Physiol Heart Circ Physiol 305:H354-64. 2013
    ..We conclude that different types of loading result in distinct patterns of RV adaptation. This is of importance for the approach to patients with chronically increased RV load and for experimental studies in various types of RV failure. ..
  3. ncbi request reprint A cornerstone of heart failure treatment is not effective in experimental right ventricular failure
    Marinus A Borgdorff
    Center For Congenital Heart Diseases, Pediatric Cardiology, Beatrix Children s Hospital, University of Groningen, University Medical Center Groningen, The Netherlands Electronic address
    Int J Cardiol 169:183-9. 2013
    ..We investigated the effects of combination treatment of aldosterone-blocker eplerenone+angiotensin II receptor blocker losartan (Ep/Lo) on RV remodeling and function in a model of RV failure due to increased pressure load...
  4. doi request reprint The role of disturbed blood flow in the development of pulmonary arterial hypertension: lessons from preclinical animal models
    Michael G Dickinson
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 305:L1-14. 2013
    ..In this review we will summarize the current knowledge obtained from PAH animal models associated with disturbed pulmonary blood flow and address questions for future treatment strategies for PAH. ..