Research Topics
| Maarten BoersSummaryAffiliation: University Hospital Vrije Universiteit Country: The Netherlands Publications
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Publications
[Roaming through methodology. XXV. Outcome measures, surrogate outcomes, and intermediate measures]M Boers
Academisch Ziekenhuis Vrije Universiteit, Afd Klinische Epidemiologie en Biostatistiek, Amsterdam
Ned Tijdschr Geneeskd 144:1949-52. 2000..the applicability of a measure can be simply appraised by answering 3 questions: 'Is the measure truthful (relevant, unbiased)?'; 'Does it discriminate between situations that are of interest?'; 'Is the measure feasible in my setting?'..
Deriving an operational definition of low disease activity state in rheumatoid arthritisMaarten Boers
VU University Medical Centre, Amsterdam, The Netherlands
J Rheumatol 30:1112-4. 2003..Once a few candidate definitions have been selected, their usefulness and prognostic validity can be tested in longitudinal datasets...
Helicobacter pylori eradication in patients on long-term treatment with NSAIDs reduces the severity of gastritis: a randomized controlled trialHelena T J I de Leest
Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
J Clin Gastroenterol 43:140-6. 2009....
Remission in early rheumatoid arthritis defined by 28 joint counts: limited consequences of residual disease activity in the forefeet on outcomeLilian H D van Tuyl
VU University Medical Centre, Department of Rheumatology, ZH 3A 56, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
Ann Rheum Dis 71:33-7. 2012..A study was undertaken to study the consequences of remission misclassification due to residual disease activity in the feet on physical function and joint damage in the subsequent year in an observational early disease cohort...
[Rheumatoid arthritis: an equally strong risk factor for cardiovascular disease as diabetes mellitus]Mike J L Peters
Vrije Universiteit Medisch Centrum, afd Reumatologie, Amsterdam, The Netherlands
Ned Tijdschr Geneeskd 154:A1469. 2010..16 (95% CI: 1.28-3.63) and 2.04 (95% CI: 1.12-3.67) respectively. CONCLUSION: RA is associated with an increased risk of CVD and this risk is similar to that associated with DM2...
Baseline RANKL:OPG ratio and markers of bone and cartilage degradation predict annual radiological progression over 11 years in rheumatoid arthritisLilian H D van Tuyl
VU University Medical Center, Department of Rheumatology, De Boelelaan 1117, Amsterdam, The Netherlands
Ann Rheum Dis 69:1623-8. 2010....
Relapse-remission and remission-relapse switches in rheumatoid arthritis patients were modeled by random effectsJohannes Berkhof
Department of Clinical Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, The Netherlands
J Clin Epidemiol 62:1085-94. 2009..To compare statistical models for the analysis of two-state disease processes...
A new graph and scoring system simplified analysis of changing states: disease remissions in a rheumatoid arthritis clinical trialMaarten Boers
Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
J Clin Epidemiol 63:633-7. 2010..However, this approach is complex and not intuitive to clinicians. In this paper we propose a simple scoring system and a graph that can enhance the information about the remission experience in a trial or cohort study...
Aggressive therapy in patients with early arthritis results in similar outcome compared with conventional care: the STREAM randomized trialIzhar C van Eijk
Jan van Breemen Research Institute Reade, Dr Jan van Breemenstraat 2, 1056 AB, Amsterdam, The Netherlands
Rheumatology (Oxford) 51:686-94. 2012..To compare the effects of aggressive tight control therapy and conventional care on radiographic progression and disease activity in patients with early mild inflammatory arthritis...
Evidence for predictive validity of remission on long-term outcome in rheumatoid arthritis: a systematic reviewLilian H D van Tuyl
Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
Arthritis Care Res (Hoboken) 62:108-17. 2010..As part of an undertaking to redefine remission, the current review describes the relationship between remission and long-term structural outcome...
Indirect and total costs of early rheumatoid arthritis: a randomized comparison of combined step-down prednisolone, methotrexate, and sulfasalazine with sulfasalazine aloneIngeborg Korthals-de Bos
Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
J Rheumatol 31:1709-16. 2004..CONCLUSION: COBRA therapy adds additional disease control (improvements in disease activity, physical function, and rate of damage progression) at lower or equal cost compared to SSZ in early RA...
Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective studyMike J L Peters
VU Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 61:1571-9. 2009..We prospectively assessed the incidence of CVD in patients with RA compared with patients with type 2 diabetes mellitus (DM) and the general population...
Direct medical costs of traumatic thoracolumbar spine fracturesNicole van der Roer
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Acta Orthop 76:662-6. 2005..The costs and cost-effectiveness of treatment of thoracolumbar fractures are poorly known...
Development of a standardized method of assessment of radiographs and radiographic change in juvenile idiopathic arthritis: introduction of the Dijkstra composite scoreMarion A J van Rossum
Emma Children s Hospital AMC, Pediatric Rheumatology, Amsterdam, The Netherlands
Arthritis Rheum 52:2865-72. 2005..To evaluate the sensitivity to change of a newly developed radiologic assessment tool, the Dijkstra score, and to develop a numeric composite score and progressor classification scheme to apply in juvenile idiopathic arthritis (JIA) trials...
Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviewsBeverley J Shea
EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
BMC Med Res Methodol 7:10. 2007..Our objective was to develop an instrument to assess the methodological quality of systematic reviews, building upon previous tools, empirical evidence and expert consensus...
Patient perspective on remission in rheumatoid arthritisLilian H D van Tuyl
VU University Medical Center, Amsterdam, The Netherlands
J Rheumatol 38:1735-8. 2011....
Defining remission in rheumatoid arthritis: results of an initial American College of Rheumatology/European League Against Rheumatism consensus conferenceLilian H D van Tuyl
VU University Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 61:704-10. 2009..The need for a uniform definition of remission is vital for research findings to be correctly interpreted...
Glucocorticoids in rheumatoid arthritis: a senescent research agenda on the brink of rejuvenation?Maarten Boers
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Best Pract Res Clin Rheumatol 18:21-9. 2004..This chapter focuses on the research agenda in urgent need of execution: to define conclusively the benefit/harm trade-offs and pin down the place of these agents in the treatment cascade...
A first step to assess harm and benefit in clinical trials in one scaleMaarten Boers
Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
J Clin Epidemiol 63:627-32. 2010..Several systems have been developed for assessment, but few attempt to incorporate both benefit and risk in the same metric while retaining enough simplicity to aid patients and clinicians in their decision making...
The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patientsHennie G Raterman
Department of Rheumatology, VU University Medical Center, De Boelelaan 1117, Amsterdam, 1081HV, The Netherlands
Arthritis Res Ther 14:R95. 2012..However, approximately 40% to 50% of rituximab (RTX) treated RA patients have a poor response. We investigated whether baseline gene expression levels can discriminate between clinical non-responders and responders to RTX...
Repeatability of 18F-FDG uptake measurements in tumors: a metaanalysisAdrianus J de Langen
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands
J Nucl Med 53:701-8. 2012..Therefore, we determined the repeatability of different standardized uptake value (SUV) measurements using the available data...
Minimally important change determined by a visual method integrating an anchor-based and a distribution-based approachHenrica C W de Vet
EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
Qual Life Res 16:131-42. 2007..Minimally important changes (MIC) in scores help interpret results from health status instruments. Various distribution-based and anchor-based approaches have been proposed to assess MIC...
Comparison of long-term clinical outcome with etanercept treatment and adalimumab treatment of rheumatoid arthritis with respect to immunogenicityCharlotte L Krieckaert
Jan van Breemen Research Institute Reade, Amsterdam, The Netherlands
Arthritis Rheum 64:3850-5. 2012....
[Prednisone for rheumatoid arthritis: the detriment of the doubt]Maarten Boers
VU Medisch Centrum, afd Epidemiologie and Biostatistiek, Amsterdam, The Netherlands
Ned Tijdschr Geneeskd 155:A5069. 2012..Existing treatment guidelines need to be urgently updated to reflect these findings...
Posttraumatic stress in aging World War II survivors after a fireworks disaster: a controlled prospective studyInge Bramsen
VU University Medical Center, Amsterdam, The Netherlands
J Trauma Stress 19:291-300. 2006..This unique controlled observation suggests that disasters do increase the levels of posttraumatic stress, and that reactivation of previous traumatic events generally occurs. However, the vulnerability hypothesis was not supported...
Practice, efficacy, and costs of thyroid nodule evaluation: a retrospective study in a Dutch university hospitalLotty Hooft
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Thyroid 14:287-93. 2004..Thyroid scintigraphy proved most productive in the inadequate FNA category. Improvement of the diagnostic process using immunohistochemistry and/or imaging is needed from the patient's and society's perspective...
Making an impact on mortality in rheumatoid arthritis: targeting cardiovascular comorbidityMaarten Boers
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 50:1734-9. 2004
Use of the American College of Rheumatology N (ACR-N) index of improvement in rheumatoid arthritis: argument in oppositionMaarten Boers
VU University Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 52:1642-5. 2005
Quantitative radiographic features of early knee osteoarthritis: development over 5 years and relationship with symptoms in the CHECK cohortMargot B Kinds
Rheumatology and Clinical Immunology, the Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
J Rheumatol 40:58-65. 2013....
Eradication of Helicobacter pylori does not reduce the incidence of gastroduodenal ulcers in patients on long-term NSAID treatment: double-blind, randomized, placebo-controlled trialHelena T J I de Leest
Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
Helicobacter 12:477-85. 2007..Helicobacter pylori and nonsteroidal antiinflammatory drugs (NSAIDs) are the major causes of gastroduodenal ulcers. Studies on the benefit of eradication of H. pylori in NSAID users yielded conflicting results...
Scope for improvement in the quality of reporting of systematic reviews. From the Cochrane Musculoskeletal GroupBeverley Shea
EMGO Institute, Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
J Rheumatol 33:9-15. 2006..To assess the quality of reporting in Cochrane musculoskeletal systematic reviews (excluding back and injury reviews)...
Delphi process yielded consensus on terminology and research agenda for therapeutic footwear for neuropathic footRutger Dahmen
Jan van Breemen Institute, Amsterdam, The Netherlands
J Clin Epidemiol 61:819-26. 2008..To investigate areas of consensus and disagreement among Dutch physiatrists concerning prescription of therapeutic footwear for the neuropathic foot and to develop a research agenda...
Progression of radiologic damage in patients with rheumatoid arthritis in clinical remissionEsmeralda T H Molenaar
VU University Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 50:36-42. 2004..This suggests the need for markers that predict progression during periods of low disease activity and for drugs that prevent damage that is independent of disease activity...
Traditional versus up-front [18F] fluorodeoxyglucose-positron emission tomography staging of non-small-cell lung cancer: a Dutch cooperative randomized studyGerarda J M Herder
Department of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands
J Clin Oncol 24:1800-6. 2006..CONCLUSION: Up-front 18FDG-PET in patients with (suspected) lung cancer does not reduce the overall number of diagnostic test, but it maintains quality of TNM staging with the use of less invasive surgery...
A call for pragmatic treatment trials in rheumatoid arthritisMaarten Boers
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Nat Clin Pract Rheumatol 4:292-3. 2008
Costs of treating bleeding and perforated peptic ulcers in The NetherlandsHelena de Leest
Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
J Rheumatol 31:788-91. 2004..We estimated the direct costs of hospital treatment of bleeding and perforated ulcers in a university hospital, from data in discharge letters and the hospital management information system...
Add-on or step-up trials for new drug development in rheumatoid arthritis: a new standard?Maarten Boers
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Arthritis Rheum 48:1481-3. 2003
Prevention or retardation of joint damage in rheumatoid arthritis: issues of definition, evaluation and interpretation of plain radiographsMaarten Boers
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands
Drugs 62:1717-24. 2002....
Is there a preferred method for scoring activity of the spine by magnetic resonance imaging in ankylosing spondylitis?Desiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht and CAPHRI Research Institute, University Maastricht, The Netherlands d vanderheijde kpnplanet nl
J Rheumatol 34:871-3. 2007..The Berlin and SPARCC methods were preferred most frequently. The development of a new method combining the best elements of all methods is an additional possibility...
Rationale and strategies for reevaluating the ACR20David T Felson
Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Rheumatol 34:1184-7. 2007..To assess whether the American College of Rheumatology response criteria ACR20 should be replaced by another definition of response with enhanced discriminant validity...
Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disordersFlorence Tubach
Département d Epidémiologie, Biostatistique et Recherche Clinique, Hopital Bichat, Paris, France
J Rheumatol 34:1188-93. 2007..The purpose of this SIG at OMERACT 8 was to inform participants of the MCII and PASS concepts and to agree on MCII and PASS values for pain, patient global assessment, and functional impairment...
Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatmentMarion A J van Rossum
Emma Children s Hospital AMC, Paediatric Rheumatology, G8 205, PO Box 22660, 1100 DD Amsterdam, The Netherlands
Ann Rheum Dis 66:1518-24. 2007..The current study determines the long-term outcome of the trial participants and evaluates whether the benefits of SSZ allocation are sustained over time...
Outcomes from the Patient Perspective Workshop at OMERACT 6John Kirwan
University of Bristol Rheumatology Unit, Bristol Royal Infirmary, Bristol, UK
J Rheumatol 30:868-72. 2003....
Minimal disease activity, remission, and the long-term outcomes of rheumatoid arthritisFrederick Wolfe
National Data Bank for Rheumatic Diseases, Wichita, Kansas 67214, USA
Arthritis Rheum 57:935-42. 2007....
Why publish a secondary analysis of only one treatment group in the Behandelstrategieën voor Reumatoide Artritis trial? Comment on the article by van der Bijl et alMaarten Boers
Arthritis Rheum 56:3876; author reply 2876-7. 2007
Studying the benefit/risk ratio of glucocorticoids in rheumatoid arthritisMaarten Boers
J Rheumatol 34:661-3. 2007
Why are Dutch rheumatologists reluctant to use the COBRA treatment strategy in early rheumatoid arthritis?Lilian H D van Tuyl
Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, PO Box 7057, 1053 MB Amsterdam, The Netherlands
Ann Rheum Dis 66:974-6. 2007..In addition, 5 years of follow-up proved that COBRA therapy results in sustained reduction of the rate of radiological progression. Despite this evidence, Dutch rheumatologists seem reluctant to prescribe COBRA therapy...
Assessing single joints in arthritis clinical trialsJon T Giles
Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21224, USA
J Rheumatol 34:641-7. 2007..At OMERACT 8, the group developed a research agenda to perform additional validation studies of clinical and functional indices, imaging, synovial histopathology, and soluble biomarkers...
MCID/Low Disease Activity State Workshop: low disease activity state in rheumatoid arthritisGeorge Wells
Department of Clinical Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
J Rheumatol 30:1110-1. 2003..This article describes the process of the MCID/Low Disease Activity State Workshop at OMERACT 6 to develop such a definition...
Repair of erosions in rheumatoid arthritis does occur. Results from 2 studies by the OMERACT Subcommittee on Healing of ErosionsJohn T Sharp
University of Washington, Seattle, Washington, USA
J Rheumatol 30:1102-7. 2003..This study provides evidence that repair of bone damage in RA does occur, resulting in some degree of improvement, which was recognized by a majority of a panel of experts...
Can progression of radiographic joint damage be predicted early in rheumatoid arthritis?Alexandre E Voskuyl
J Rheumatol 30:905-7. 2003
Economic evaluation of programs or interventions in the management of rheumatoid arthritis: defining a consensus-based reference caseAndreas Maetzel
Division of Clinical Decision Making and Health Care Research, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
J Rheumatol 30:891-6. 2003..We provide the rationale for each element and discuss how each element has been addressed in published economic evaluations of DMARD...
OMERACT 6 Economics Working Group report: a proposal for a reference case for economic evaluation in rheumatoid arthritisSherine Gabriel
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
J Rheumatol 30:886-90. 2003..Through these efforts, the OMERACT Economics Working Group aims to expedite and enhance the conduct and dissemination of methodological research in economic analyses in the rheumatic diseases...
Radiologic features in juvenile idiopathic arthritis: a first step in the development of a standardized assessment methodMarion A J van Rossum
Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 48:507-15. 2003....
Association of baseline levels of markers of bone and cartilage degradation with long-term progression of joint damage in patients with early rheumatoid arthritis: the COBRA studyPatrick Garnero
INSERM Research Unit 403, and Synarc, Lyon, France
Arthritis Rheum 46:2847-56. 2002....
Detecting radiological changes in rheumatoid arthritis that are considered important by clinical experts: influence of reading with or without known sequenceKarin Bruynesteyn
Division of Rheumatology, Maastricht University, Maastricht, The Netherlands
J Rheumatol 29:2306-12. 2002....
Contribution of progression of erosive damage in previously eroded joints in early rheumatoid arthritis trials: COBRA trial as an exampleKarin Bruynesteyn
University of Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:532-6. 2002..The aim of this study is to evaluate the relative contribution of separate components of the erosion score of the modified Sharp/van der Heijde method in early RA...
How to report radiographic data in randomized clinical trials in rheumatoid arthritis: guidelines from a roundtable discussionDesiree van der Heijde
Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:215-8. 2002
Determination of the minimal clinically important difference in rheumatoid arthritis joint damage of the Sharp/van der Heijde and Larsen/Scott scoring methods by clinical experts and comparison with the smallest detectable differenceKarin Bruynesteyn
Maastricht University, Maastricht, The Netherlands
Arthritis Rheum 46:913-20. 2002....
MCID/Low Disease Activity State Workshop: summary, recommendations, and research agendaGeorge Wells
Department of Clinical Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Rheumatol 30:1115-8. 2003..This article presents an overview of that workshop, including results of the voting, a summary of associated discussions, recommendations, and a proposed research agenda...
Understanding the window of opportunity concept in early rheumatoid arthritisMaarten Boers
Arthritis Rheum 48:1771-4. 2003
Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritisRobert Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 50:1390-9. 2004....
Development of draft validation criteria for a soluble biomarker to be regarded as a valid biomarker reflecting structural damage endpoints in rheumatoid arthritis and spondyloarthritis clinical trialsWalter P Maksymowych
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
J Rheumatol 34:634-40. 2007..Our objective was to develop validation criteria for a soluble biomarker to be regarded as a valid biomarker reflecting radiological endpoints in RA and SpA clinical trials...
Testing of the preliminary OMERACT validation criteria for a biomarker to be regarded as reflecting structural damage endpoints in rheumatoid arthritis clinical trials: the example of C-reactive proteinStephanie O Keeling
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
J Rheumatol 34:623-33. 2007..2) To assess the strength of recommendation for inclusion of individual criteria in the draft set...
Abatacept in rheumatoid arthritis: a new branch on the "biologics" treeMaarten Boers
Ann Intern Med 144:933-5. 2006
The benefit of low-dose glucocorticoid treatment in early rheumatoid arthritis may outweigh the risk: comment on the editorial by HarrisJohannes W G Jacobs
Arthritis Rheum 54:2031-2; author reply 2032. 2006
The relationship between disease activity and radiologic progression in patients with rheumatoid arthritis: a longitudinal analysisPaco M J Welsing
University Medical Center Nijmegen, Nijmegen, The Netherlands
Arthritis Rheum 50:2082-93. 2004..Fluctuations in disease activity are directly related to changes in radiologic progression, which supports the hypothesis that disease activity causes radiologic damage. This relationship might only exist in RF-positive patients...
Rationale and design of The Delphi Trial--I(RCT)2: international randomized clinical trial of rheumatoid craniocervical treatment, an intervention-prognostic trial comparing 'early' surgery with conservative treatment [ISRCTN65076841]Jasper F C Wolfs
Department of Neurosurgery, Leiden University Medical Center, The Netherlands
BMC Musculoskelet Disord 7:14. 2006..If signs and symptoms of myelopathy are present there is little chance of recovery to normal levels after surgery...
Current status of outcome measures in vasculitis: focus on Wegener's granulomatosis and microscopic polyangiitis. Report from OMERACT 7Peter A Merkel
Boston University School of Medicine, Boston, MA 02118, USA
J Rheumatol 32:2488-95. 2005....
Minimal disease activity for rheumatoid arthritis: a preliminary definitionGeorge A Wells
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
J Rheumatol 32:2016-24. 2005..This set of 2 definitions gained approval of 73% of the attendees. These (and other) definitions will now be subject to further validation in other databases...
The Sharp/van der Heijde method out-performed the Larsen/Scott method on the individual patient level in assessing radiographs in early rheumatoid arthritisKarin Bruynesteyn
Department of Internal Medicine, Division of Rheumatology, University of Maastricht, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands
J Clin Epidemiol 57:502-12. 2004..2%). The SvH also assessed changes in scores in individuals with less measurement error (SDCs 1.3-2.2%) than the LS (SDCs 2.3-3.9%). CONCLUSION: For early RA patients, the SvH seems preferable if analyses on individual level are included...
Variability of precision in scoring radiographic abnormalities in rheumatoid arthritis by experienced readersJohn T Sharp
University of Washington School of Medicine, Seattle, Washington, USA
J Rheumatol 31:1062-72. 2004..To determine the extent of precision and sources of variability among experts on scoring radiographic abnormalities in rheumatoid arthritis...
Evidence for interaction between disease severity and comorbidity in rheumatoid arthritis? comment on the article by Navarro-Cano et alMaarten Boers
Arthritis Rheum 50:1695; author reply 1696-7. 2004
COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief interventionRobert B M Landewe
Department of Internal Medicine Rheumatology, PO Box 5800, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 46:347-56. 2002..The current study was conducted to investigate whether the benefits of COBRA therapy were sustained over time, and to determine which baseline factors could predict outcome...
